Austrian “Kingdom of Serbia” (1718- 1739). The Infrastructural Innovations introduced by the Habsburg DominationFabrizio Rudi
From the Treaty of Passarowitz up to the Treaty of Belgrade, Austrian domination of Northern Serbia, and also of Posavina, Oltenia and Banat improved, although temporarily, the former Ottoman administrative apparatus even if only temporarily. While a Commissio Neoacquistica nominated the administrative personnel for the new acquired lands exclusively among the personalities of greater trust for the Viennese court, the local population knew some important infrastructural benefits whose effects weren’t completely cancelled after the 1739...
Litter decomposition mobilizes nutrients that sustain ecosystem productivity, but decomposition by-products may also hamper root proliferation by phytotoxicity. The aim of this study was to assess the litter substrate preferences of tropical tree seedlings in relation to litter chemical traits. We characterized 44 litter types (11 species at 4 decomposition ages; 0, 30, 90 and 180 days) for nutrients (N, P, K, Mg, Mn, Na, Fe and Zn) and proximate chemical parameters (cellulose, extractive, lignin...
Type 2 diabetes (T2D) is a global public health challenge. Whilst the advent of genome-wide association studies has identified >400 genetic variants associated with T2D, our understanding of its biological mechanisms and translational insights is still limited. The EPIC-InterAct project, centred in 8 countries in the European Prospective Investigations into Cancer and Nutrition study, is one of the largest prospective studies of T2D. Established as a nested case-cohort study to investigate the interplay between genetic...
Data from: A method for mapping morphological convergence on three-dimensional digital models: the case of the mammalian saber-toothPasquale Raia, Marina Melchionna, Antonio Profico, Silvia Castiglione, Carmela Serio, Alessandro Mondanaro, Maria Modafferi, Davide Tamagnini, Luigi Maiorano, Pasquale Raia, Stephen Wroe, Lawrence Witmer & Gabriele Sansalone
Morphological convergence can be assessed through a variety of statistical methods. None of the methods proposed to date enable the visualization of convergence. All are based on the assumption that the phenotypes either converge, or do not. However, between species, morphologically similar regions of a larger structure may behave differently. Previous approaches do not identify these regions within the larger structures or quantify the degree to which they may contribute to overall convergence. Here we...
Variation in the strength of allometry drives rates of evolution in primate brain shape - Supplementary MaterialGabriele Sansalone, Kari Allen, Justin Ledogar, Sarah Heinz Ledogar, D. Rex Mitchell, Antonio Profico, Silvia Castiglione, Marina Melchionna, Carmela Serio, Alessandro Mondanaro, Pasquale Raia & Stephen Wroe
Large brains are a defining feature of primates, as is a clear allometric trend between body mass and brain size. However, important questions on the macroevolution of brain shape in primates remain unanswered. Here we address two: (i), does the relationship between the brain size and its shape follow allometric trends and (ii), is this relationship consistent over evolutionary time? We employ three-dimensional geometric morphometrics and phylogenetic comparative methods to answer these questions, based on...
Rcodes and additional results from identifying trait-associated diversification with fossil phylogeniesPasquale Raia
There is solid theoretical reasoning but few statistical approaches available to test the hypothesis that phenotypic traits and phenotypic evolutionary rates could be associated to rates of taxonomic diversification. A positive relationship between phenotypic and taxonomic evolution is expected to occur during adaptive radiations, or when the acquisition of key innovations allows rapid expansion into new adaptive zones. Such patterns of trait-associated diversification are intensely studied under both neontological and paleontological approaches. However, albeit the...
Objective: To delineate the full phenotypic spectrum, discriminative features, piloting longitudinal progression data, and sample size calculations of RFC1-repeat expansions, recently identified as causing cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS). Methods: Multimodal RFC1 repeat screening (PCR, southern blot, whole-exome/genome (WES/WGS)-based approaches) combined with cross-sectional and longitudinal deep-phenotyping in (i) cross-European cohort A (70 families) with ≥2 features of CANVAS and/or ataxia-with-chronic-cough (ACC); and (ii) Turkish cohort B (105 families) with unselected late-onset ataxia. Results:...
Similitude methods are a set of tools which allow the design of scaled-up or scaled-down models of a full-scale structure called a prototype. In this way, the financial and temporal costs of experimental tests, and the problems associated with the set-up of too large (or small) test articles, may be overcome. This article provides a brief review of similitude methods applied to plates in a vibroacoustic field. Particularly, it is dedicated to a thorough analysis...
University of Naples Federico II8
University of New England2
Institut d'Investigació Biomédica de Bellvitge1
Instituto de Salud Pública de Navarra1
Institute of Genetics and Molecular and Cellular Biology1
Azienda Ospedaliera Citta' Della Salute E Della Scienza Di Torino1
Karolinska University Hospital1
University of Strasbourg1