126 Works

Data from: Hsp70 protein levels and thermotolerance in Drosophila subobscura: a reassessment of the thermal co-adaptation hypothesis

Gemma Calabria, Olga Dolgova, Carla Rego, Luís E. Castañeda, Enrico L. Rezende, Joan Balanyà, Marta Pascual, Jesper G. Sørensen, Volker Loeschcke & Mauro Santos
Theory predicts that geographic variation in traits and genes associated with climatic adaptation may be initially driven by the correlated evolution of thermal preference and thermal sensitivity. This assumes that an organism’s preferred body temperature corresponds with the thermal optimum in which performance is maximized; hence, shifts in thermal preferences affect the subsequent evolution of thermal-related traits. Drosophila subobscura evolved world-wide latitudinal clines in several traits including chromosome inversion frequencies, with some polymorphic inversions being...

Data from: Analysis of the porcine APOA2 gene expression in liver, polymorphisms identification and association with fatty acid composition traits

M. Ballester, M. Revilla, A. Puig-Oliveras, J. A. P. Marchesi, A. Castello, J. Corominas, A. I. Fernandez & J. M. Folch
APOA2 is a protein implicated in triglyceride, fatty acid and glucose metabolism. In pigs, the APOA2 gene is located on pig chromosome 4 (SSC4) in a QTL region affecting fatty acid composition, fatness and growth traits. In this study, we evaluated APOA2 as a candidate gene for meat quality traits in an Iberian × Landrace backcross population. The APOA2:c.131T>A polymorphism, located in exon 3 of APOA2 and determining a missense mutation, was associated with the...

Cortical microstructural correlates of astrocytosis in autosomal dominant Alzheimer disease

Eduard Vilaplana, Elena Rodriguez-Vieitez, Daniel Ferreira, Victor Montal, Ove Almkvist, Anders Wall, Alberto Lleo, Eric Westman, Caroline Graff, Juan Fortea & Agneta Nordberg
Objective To study the macrostructural and microstructural MRI correlates of brain astrocytosis, measured with 11C-deuterium-L-deprenyl (11C-DED)–PET, in familial autosomal dominant Alzheimer disease (ADAD). Methods The total sample (n = 31) comprised ADAD mutation carriers (n = 10 presymptomatic, 39.2 ± 10.6 years old; n = 3 symptomatic, 55.5 ± 2.0 years old) and noncarriers (n = 18, 44.0 ± 13.7 years old) belonging to families with mutations in either the presenilin-1 or amyloid precursor protein...

HDL particle size and cholesterol content in Heart Failure. Supplementary Material

Albert Teis, German Cediel, Nuria Amigo, Josep Julve, Julia Aranyo, Joan Andres, Carlos Puig-Jove, Esmeralda Castellblanco, Francisco Gual-Capllonch, Elena Ferrer-Sistach, Nuria Vallejo, Gladys Juncà, Jorge López-Ayerbe, Marta De Antonio, Mar Domingo, Evelyn Santiago-Vacas, Pau Codina, Didac Mauricio, Josep Lupón, Nuria Alonso & Antonio Bayes-Genis
Supplementary material corresponding to the article entitled Particle Size and Cholesterol Content of circulating HDL correlate with Cardiovascular Death in Chronic Heart Failure.

Data from: Abundance and morphometry changes across the high-mountain lake-size gradient in the tropical Andes of Southern Ecuador

Pablo V. Mosquera, Henrietta Hampel, Raúl F. Vázquez, Miguel Alonso & Jordi Catalan
The number, size, and shape of lakes are key determinants of the ecological functionality of a lake district. The lake area scaling relationships with lake number and volume enable upscaling biogeochemical processes and spatially considering organisms' metapopulation dynamics. These relationships vary regionally depending on the geomorphological context, particularly in the range of lake area <1 km2 and mountainous regions. The Cajas Massif (Southern Ecuador) holds a tropical mountain lake district with 5955 water bodies. The...

Solidarity Purchasing Groups in Italy: A critical assessment of their effects on the marginalisation of their suppliers.

Lara Ivana Maestripieri, Toa Giroletti & Antonello Podda
Over the last twenty years, Alternative Food Networks (AFN) have become increasingly successful at reducing the length of the chain that connects food production and consumption in an attempt to counteract the impact of the contradictions of the industrial food system and its supermarket-dominated distribution. Their grassroots actions, aimed at overcoming pre-existing socio-economic structures, are in line with social innovations, which have the objective of promoting the social participation of consumers and producers in food...

Genetic response to human‐induced habitat changes in the marine environment: A century of evolution of European sprat in Landvikvannet, Norway

María Quintela, Cecilie Kvamme, Dorte Bekkevold, Richard D. M. Nash, Eeva Jansson, Geir Dahle, Kevin A. Glover, Àlex Richter‐Boix, Florian Berg & François Besnier
Habitat changes represent one of the five most pervasive threats to biodiversity. However, anthropogenic activities also have the capacity to create novel niche spaces to which species respond differently. In 1880, one such habitat alterations occurred in Landvikvannet, a freshwater lake on the Norwegian coast of Skagerrak, which became brackish after being artificially connected to the sea. This lake is now home to the European sprat, a pelagic marine fish that managed to develop a...

Additional file 1 of A CT-based nomogram for differentiating invasive fungal disease of the lung from bacterial pneumonia

Meilin Gong, Jingmei Xu, Kang Li, Ke Li, Yuwei Xia, Yang Jing, Jiafei Chen, Jing Li, Jing Yang, Mingshan Du, Wenjing Hou, Yuan Ou, Lian Li & Wei Chen
Additional file 1. On the orininal data of the study.

sj-xlsx-2-tct-10.1177_15330338221124658 - Supplemental material for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia & Yujun Wang
Supplemental material, sj-xlsx-2-tct-10.1177_15330338221124658 for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells by Mike Y. Chen, Jing Li, Nianli Zhang and Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia, Yujun Wang in Technology in Cancer Research & Treatment

sj-xlsx-3-tct-10.1177_15330338221124658 - Supplemental material for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

Mike Y. Chen, Jing Li, Nianli Zhang, Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia & Yujun Wang
Supplemental material, sj-xlsx-3-tct-10.1177_15330338221124658 for In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells by Mike Y. Chen, Jing Li, Nianli Zhang and Erik I. Waldorff, James T. Ryaby, Philip Fedor, Yongsheng Jia, Yujun Wang in Technology in Cancer Research & Treatment

Association between healthy lifestyle and the occurrence of cardiometabolic multimorbidity in hypertensive patients: a prospective cohort study of UK Biobank

Hejian Xie, Jinchen Li, Xuanmeng Zhu, Jing Li, Jinghua Yin, Tianqi Ma, Yi Luo, Lingfang He, Yongping Bai, Guogang Zhang, Xunjie Cheng & Chuanchang Li
Abstract Background Cardiometabolic multimorbidity (CMM) is becoming increasingly common in patients with hypertension, and it is well established that healthy lifestyle plays a key role in the prevention of hypertension. However, the association between combined lifestyle factors and CMM in patients with hypertension is uncertain. Methods This prospective analysis included the data (obtained from the UK biobank) of participants with hypertension who did not have coronary heart disease (CHD), stroke, or diabetes. The outcome was...

Additional file 1 of Association between healthy lifestyle and the occurrence of cardiometabolic multimorbidity in hypertensive patients: a prospective cohort study of UK Biobank

Hejian Xie, Jinchen Li, Xuanmeng Zhu, Jing Li, Jinghua Yin, Tianqi Ma, Yi Luo, Lingfang He, Yongping Bai, Guogang Zhang, Xunjie Cheng & Chuanchang Li
Additional file 1: Figure S1. The relationship between a healthy lifestyle and CMM in subgroup analyses. Figure S2. The relationship between a healthy lifestyle and CMM in seven sensitivity analyses. Figure S3. The frequency distribution graph of the weighted healthy lifestyle score for the whole population. Figure S4. The frequency distribution graph of the weighted healthy lifestyle score for 2/3 of the population. Figure S5. The frequency distribution graph of the sum healthy lifestyle score...

Association between healthy lifestyle and the occurrence of cardiometabolic multimorbidity in hypertensive patients: a prospective cohort study of UK Biobank

Hejian Xie, Jinchen Li, Xuanmeng Zhu, Jing Li, Jinghua Yin, Tianqi Ma, Yi Luo, Lingfang He, Yongping Bai, Guogang Zhang, Xunjie Cheng & Chuanchang Li
Abstract Background Cardiometabolic multimorbidity (CMM) is becoming increasingly common in patients with hypertension, and it is well established that healthy lifestyle plays a key role in the prevention of hypertension. However, the association between combined lifestyle factors and CMM in patients with hypertension is uncertain. Methods This prospective analysis included the data (obtained from the UK biobank) of participants with hypertension who did not have coronary heart disease (CHD), stroke, or diabetes. The outcome was...

Interactions of CDKAL1 rs7747752 polymorphism and serum levels of L-carnitine and choline are related to increased risk of gestational diabetes mellitus

Hui Wang, Jing Li, Jinnan Liu, Junhong Leng, Weiqin Li, Zhijie Yu, Claudia H. T. Tam, Gang Hu, Ronald C. W. Ma, Zhongze Fang, Ying Wang & Xilin Yang
Abstract Background Interactions between genetic, metabolic, and environmental factors lead to gestational diabetes mellitus (GDM). We aimed to examine interactive effects of cyclin-dependent kinase 5 regulatory subunit-associated protein1-like 1(CDKAL1) rs7747752 polymorphism with low serum levels of L-carnitine, choline, and betaine for GDM. Methods A nested case-control study of 207 GDM women and their one-to-one, age-matched controls was organized from a prospective cohort of pregnant women in Tianjin, China. Conditional logistic regressions were used to test...

Additional file 1 of ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways

Jing Li, Haoran Du, Xin Ji, Yihan Chen, Yishuai Li, Boon Chin Heng & Jianguang Xu
Additional file 1: Figure S1. The mRNA level of CBFA1 in qRT-PCR (a) and RNA-Seq (b). *P < 0.05.

Additional file 4 of ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways

Jing Li, Haoran Du, Xin Ji, Yihan Chen, Yishuai Li, Boon Chin Heng & Jianguang Xu
Additional file 4: Figure S4. HE (scale bar = 50 μm) and Masson (scale bar = 50 μm) staining were performed to evaluate ectopic bone formation in nude mice (n=4).

Additional file 1 of Botulinum toxin treatment for bielschowsky acquired commitant esotropia in adults

Likun Ai, Xiaoli Chen, Ruilin Guo, Jing Li, Jinghui Wang, Yi Feng, Yiqin Guo & Jianan Wang
Supplementary Material 1

Additional file 1 of 5-Methoxyflavone-induced AMPKα activation inhibits NF-κB and P38 MAPK signaling to attenuate influenza A virus-mediated inflammation and lung injury in vitro and in vivo

Sushan Yang, Linxin Wang, Xiping Pan, Yueyun Liang, Yuehan Zhang, Jing Li & Beixian Zhou
Additional file 1. Original images for western blot.

Additional file 4 of Descriptive analyses of maternally-derived antibody levels against porcine circovirus 2 (PCV-2) in 3- and 21-day-old piglets from farms of four European countries using different vaccination protocols in sows

M. Sibila, A. Llorens, E. Huerta, C. Fablet, M. Faderl, L. Ferrari, N. Rose, A. Palzer, P. Martelli, M. C. Venegas-Vargas, D. Fredrickson, L. Taylor, M. Balasch, M. Bandrick & J. Segalés
Additional file 4. Table S4. Characteristics of the 30 Spanish Farms included in this study.

Data from: Universal and blocking primer mismatches limit the use of high-throughput DNA sequencing for the quantitative metabarcoding of arthropods

Josep Piñol, Gisela Mir, Priscila Gomez-Polo & Nuria Agusti
The quantification of the biological diversity in environmental samples using high-throughput DNA sequencing is hindered by the PCR bias caused by variable primer–template mismatches of the individual species. In some dietary studies, there is the added problem that samples are enriched with predator DNA, so often a predator-specific blocking oligonucleotide is used to alleviate the problem. However, specific blocking oligonucleotides could coblock nontarget species to some degree. Here, we accurately estimate the extent of the...

Data from: Relationships among taxonomic, functional, and phylogenetic ant diversity across the biogeographic regions of Europe

Xavier Arnan, Xim Cerdá & Javier Retana
Understanding how different biodiversity components are related across different environmental conditions is a major goal in macroecology and conservation biogeography. We investigated correlations among alpha and beta taxonomic (TD), phylogenetic (PD), and functional diversity (FD) in ant communities in the five biogeographic regions most representative of western Europe; we also examined the degree of niche conservatism. We combined data from 349 ant communities composed of 154 total species, which were characterized by 10 functional traits...

Data from: Combined exposure to sublethal concentrations of an insecticide and a fungicide affect feeding, ovary development and longevity in a solitary bee

Fabio Sgolastra, Xavier Arnan, Riccardo Cabbri, Gloria Isani, Piotr Medrzycki, Dariusz Teper & Jordi Bosch
Pollinators in agroecosystems are often exposed to pesticide mixtures. Even at low concentrations, the effects of these mixtures on bee populations are difficult to predict due to potential synergistic interactions. We orally exposed newly-emerged females of the solitary bee Osmia bicornis to environmentally-realistic levels of clothianidin (neonicotinoid insecticide) and propiconazole (fungicide), singly and in combination. The amount of feeding solution consumed was highest in bees exposed to the neonicotinoid, and lowest in bees exposed to...

Data from: Selection on structural allelic variation biases plasticity estimates

Mauro Santos, Margarida Matos, Sheng Pei Wang & David M Althoff
Wang and Althoff (2019) explored the capacity of Drosophila melanogaster to exhibit adaptive plasticity in a novel environment. In a full-sib, half-sib design, they scored the activity of the enzyme alcohol dehydrogenase (ADH) and plastic responses, measured as changes in ADH activity across ethanol concentrations in the range of 0-10% (natural variation) and 16% (the novel environment). ADH activity increased with alcohol concentration, and there was a positive association between larval viability and ADH activity...

Ecological network complexity scales with area

Nuria Galiana
Larger geographical areas contain more species–an observation raised to a law in ecology. Less explored is whether biodiversity changes are accompanied by a modification of interaction networks. We use data from 32 spatial interaction networks from different ecosystems to analyse how network structure changes with area. We find that basic community structure descriptors (number of species, links, and links per species) increase with area following a power-law. Yet, the distribution of links per species varies...

Divergence time estimation using ddRAD data and an isolation-with-migration model applied to water vole populations of Arvicola

Jose Castresana, Alfonso Balmori-De La Puente, Jacint Ventura, Marcos Miñarro, Aitor Somoano & Jody Hey
Molecular dating methods of population splits are crucial in evolutionary biology, but they present important difficulties due to the complexity of the genealogical relationships of genes and past migrations between populations. Using the double digest restriction-site associated DNA (ddRAD) technique and an isolation-with-migration (IM) model, we studied the evolutionary history of water vole populations of the genus Arvicola, a group of complex evolution with fossorial and semi-aquatic ecotypes. To do this, we first estimated mutation...

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