10 Works

Cortical microstructural correlates of astrocytosis in autosomal dominant Alzheimer disease

Eduard Vilaplana, Elena Rodriguez-Vieitez, Daniel Ferreira, Victor Montal, Ove Almkvist, Anders Wall, Alberto Lleo, Eric Westman, Caroline Graff, Juan Fortea & Agneta Nordberg
Objective To study the macrostructural and microstructural MRI correlates of brain astrocytosis, measured with 11C-deuterium-L-deprenyl (11C-DED)–PET, in familial autosomal dominant Alzheimer disease (ADAD). Methods The total sample (n = 31) comprised ADAD mutation carriers (n = 10 presymptomatic, 39.2 ± 10.6 years old; n = 3 symptomatic, 55.5 ± 2.0 years old) and noncarriers (n = 18, 44.0 ± 13.7 years old) belonging to families with mutations in either the presenilin-1 or amyloid precursor protein...

HDL particle size and cholesterol content in Heart Failure. Supplementary Material

Albert Teis, German Cediel, Nuria Amigo, Josep Julve, Julia Aranyo, Joan Andres, Carlos Puig-Jove, Esmeralda Castellblanco, Francisco Gual-Capllonch, Elena Ferrer-Sistach, Nuria Vallejo, Gladys Juncà, Jorge López-Ayerbe, Marta De Antonio, Mar Domingo, Evelyn Santiago-Vacas, Pau Codina, Didac Mauricio, Josep Lupón, Nuria Alonso & Antonio Bayes-Genis
Supplementary material corresponding to the article entitled Particle Size and Cholesterol Content of circulating HDL correlate with Cardiovascular Death in Chronic Heart Failure.

Solidarity Purchasing Groups in Italy: A critical assessment of their effects on the marginalisation of their suppliers.

Lara Ivana Maestripieri, Toa Giroletti & Antonello Podda
Over the last twenty years, Alternative Food Networks (AFN) have become increasingly successful at reducing the length of the chain that connects food production and consumption in an attempt to counteract the impact of the contradictions of the industrial food system and its supermarket-dominated distribution. Their grassroots actions, aimed at overcoming pre-existing socio-economic structures, are in line with social innovations, which have the objective of promoting the social participation of consumers and producers in food...

Dataset and scripts from: Predicting temperature mortality and selection in natural Drosophila populations

Enrico Rezende, Francisco Bozinovic, András Szilágyi & Mauro Santos
The study develops and validates a theoretical model to predict thermal mortality under natural conditions, based on measurements of mortality performed in the laboratory at multiple constant temperatures. The theoretical model first fits a thermal tolerance landscape, which describes how survival probability is affected by both temperature and exposure time, to the empirical measurements of mortality obtained in the laboratory under controlled conditions. Then, employing a numerical approximation to the analytical solution based on differential...

Estimation of the relative abundance of species in artificial mixtures of insects using low-coverage shotgun metagenomics

Lidia Garrido-Sanz, Miquel Àngel Senar & Josep Piñol
Amplicon metabarcoding is an established technique to analyse the taxonomic composition of communities of organisms using high-throughput DNA sequencing, but there are doubts about its ability to quantify the relative proportions of the species, as opposed to the species list. Here, we bypass the enrichment step and avoid the PCR-bias, by directly sequencing the extracted DNA using shotgun metagenomics. This approach is common practice in prokaryotes, but not in eukaryotes, because of the low number...

Effects of soil salinity on the expression of direct and indirect defences in wild cotton (Gossypium hirsutum)

Luis Abdala-Roberts, Teresa Quijano-Medina, Ted Turlings, Paula Sosenski, Luca Grandi, Jose Cervera & Xoaquin Moreira
Previous studies have reported effects of abiotic factors on herbivore-induced plant defences based on effects on single plant traits. However, plants commonly express multiple defences simultaneously and these traits are often correlated. Thus, a fuller understanding of abiotic-context dependency in plant defence requires measuring multiple traits and addressing their patterns of correlated expression. We evaluated the effects of soil salinity on the induction of direct (phenolic compounds, gossypol gland density) and indirect (volatile organic compounds,...

Nurses coping with daily stressors

Fermín Martínez-Zaragoza, Gemma Benavides-Gil, Tatiana Rovira, Silvia Edo, Rosa García-Sierra, Ángel Solanes-Puchol, Jordi Fernández-Castro & Beatriz Martín-Del-Río
Background: During their workday, nurses face a variety of stressors that are dealt with using different coping strategies. One criticism of the contextual models of work stress is that they fail to focus on individual responses like coping with stress. Neverthless, little is know about the momentary determinants of coping in nurses. Objectives: To identify the momentary predictors of problem-focused approaching coping and emotion-focused approaching coping, as well as those for seeking social support and...

Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways

Aimin Liu, Buxin Zhang, Wei Zhao, Yuanhui Tu, Qingxing Wang & Jing Li
Psoriasis is a chronic inflammatory skin disease that affects approximately 2% of worldwide population, and causing long-term troubles to the patients. Therefore, it is urgent to develop safe and effective therapeutic drugs. Catalpol is a natural iridoid glucoside, that has several remarkable pharmacological effects, however, whether catalpol can alleviated psoriasis has not been explored. The goal of the present work is to study the role of catalpol in psoriasis in vivo and in vitro. Imiquimod-induced...

Are leaf, stem and hydraulic traits good predictors of individual tree growth? (FUN2FUN project)

Jordi Martinez-Vilalta, Teresa Rosas, Maurizio Mencuccini, Carles Batlles, Íngrid Regalado, Sandra Saura-Mas & Frank Sterck
A major foundation of trait-based ecology is that traits have an impact on individual performance. However, trait-growth relationships have not been extensively tested in trees, especially outside tropical ecosystems. In addition, measuring traits directly related to physiological processes (‘hard traits’) remains difficult and the differences between inter- and intraspecific relationships are seldom explored. Here, we use individual-level data on a set of hydraulic, leaf and stem traits to explore which traits are the best predictors...

Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways

Aimin Liu, Buxin Zhang, Wei Zhao, Yuanhui Tu, Qingxing Wang & Jing Li
Psoriasis is a chronic inflammatory skin disease that affects approximately 2% of worldwide population, and causing long-term troubles to the patients. Therefore, it is urgent to develop safe and effective therapeutic drugs. Catalpol is a natural iridoid glucoside, that has several remarkable pharmacological effects, however, whether catalpol can alleviated psoriasis has not been explored. The goal of the present work is to study the role of catalpol in psoriasis in vivo and in vitro. Imiquimod-induced...

Registration Year

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Affiliations

  • Autonomous University of Barcelona
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  • State Administration of Traditional Chinese Medicine of the People's Republic of China
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  • Chinese Academy of Tropical Agricultural Sciences
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  • Henan University
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  • Hebei Normal University
    2
  • North West Agriculture and Forestry University
    2
  • Sun Yat-sen University
    2
  • West China Hospital of Sichuan University
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  • Zhejiang University
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  • First People's Hospital of Yunnan Province
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