Supplemental material, sj-pdf-10-pal-10.1177_08258597221138674 for Clinical Practice Guidelines on Palliative Sedation Around the World: A Systematic Review by Martyna Tomczyk, Cécile Jaques and Ralf J. Jox in Journal of Palliative Care

Supplemental material, sj-pdf-12-pal-10.1177_08258597221138674 for Clinical Practice Guidelines on Palliative Sedation Around the World: A Systematic Review by Martyna Tomczyk, Cécile Jaques and Ralf J. Jox in Journal of Palliative Care

Supplemental material, sj-pdf-13-pal-10.1177_08258597221138674 for Clinical Practice Guidelines on Palliative Sedation Around the World: A Systematic Review by Martyna Tomczyk, Cécile Jaques and Ralf J. Jox in Journal of Palliative Care

Objective: The principal aim of this study was to identify, systematically and transparently, clinical practice guidelines (CPGs) on palliative sedation from around the world. Methods: A systematic search was performed using 5 databases, grey literature search tools, citation tracking, and contact with palliative care experts across the world. Current CPGs accredited by an international, national, or regional authority, published in English, German, French, or Italian, were subjected to content analysis. Results: In total, 35 CPGs...

Additional file 1. Full study protocol

Additional file 2: Fig. S2. Scatterplot and regression line (with 95% confidence intervals) to describe the relationship of hs-CRP with characteristics of study participants. Relationship between hs-CRP and A) age, B) sex, C) BMI and D) polygenic risk score (PRS). For linear regressions, linear regression equation, R-squared and P-value are shown.

Additional file 4: Fig. S4. Distribution of polygenic risk score (PRS) values. Density distribution of standardized PRS values by subcohort (CoLaus|PsyCoLaus and UKB) and across all participants (combined).

Supplementary Material 1

Supplementary Material 2

Candida species are the most commonly isolated opportunistic fungal pathogens in humans. These species exhibit very different infection strategies, since they acquired pathogenesis independently throughout evolution. Candida albicans causes most of the diagnosed infections, closely followed by Candida glabrata. C. albicans is well studied, and many genes have been shown to be important for infection and colonization of the host. It is, however, less clear how C. glabrata infects the host. With the help of...

Additional file 1: Table S1: Patients’ characteristics. Table S2: Detail of patient current treatment. Table S3: Clinical data at inclusion. Figure S1: Carry-over effect. Figure S2: plasma total homocysteine (tHcy) before and after one month treatment with 100 mg/kg/day) (A, D) or 250 mg/kg/day (B, E) in pnrCBS patients (A, B) and cblC patients (B, E) and the corresponding difference (ΔtHcy) for each pnrCBS (C) and cblC (F) patient. Figure S3: SAM (A, B), SAH...

Additional file 1. Individual radiomics features for the free-breathing and data-driven gating PET/CT data sets. Individual radiomics features values for the free-breathing (flow) and data-driven gating (DDG) PET/CT reconstruction of each pulmonary lesion. The radiomics features table is the output from the QuantImage platform (see Cid et al. (2017)).

Abstract This paper presents a synchronic analysis of the diseases during the emergence of COVID-19, the management and impact of the lockdown, and how the media narrated these events in working-class neighborhoods of the metropolitan areas of Buenos Aires and Gran Resistencia from March to November 2020. We resorted to quantitative methods on secondary sources to describe poverty and syndemics and conducted week-by-week ethnographic and media research on 38 neighborhoods with water shortages and critical...

Additional file 1: Supplementary Methods, Results, Tables and Figures.

Abstract Background Ventilator-associated pneumonia caused by Pseudomonas aeruginosa (PA) in hospitalised patients is associated with high mortality. The effectiveness of the bivalent, bispecific mAb MEDI3902 (gremubamab) in preventing PA nosocomial pneumonia was assessed in PA-colonised mechanically ventilated subjects. Methods EVADE (NCT02696902) was a phase 2, randomised, parallel-group, double-blind, placebo-controlled study in Europe, Turkey, Israel, and the USA. Subjects ≥ 18 years old, mechanically ventilated, tracheally colonised with PA, and without new-onset pneumonia, were randomised (1:1:1)...

Supplemental Material for A Retrospective Study of the Role of Perioperative Serum Albumin and the Albumin-Bilirubin Grade in Predicting Post-Liver Transplant Length of Stay by Ryan Wang, Daniel Katz, Hung-Mo Lin, Yuxia Ouyang, Jonathan Gal, Sumanth Suresh, Ismail Labgaa, Parissa Tabrizian, Samuel Demaria, Jeron Zerillo, and Natalie K. Smith in Seminars in Cardiothoracic and Vascular Anesthesia

IntroductionSerum albumin’s association with liver transplant outcomes has been investigated with mixed findings. This study aimed to evaluate perioperative albumin level, independently and as part of the albumin–bilirubin (ALBI) grade, as a predictor of post-liver transplant hospital and intensive care unit (ICU) length of stay (LOS).MethodsAdult liver-only transplant recipients at our institution from September 2011 to May 2019 were included in this retrospective study. Repeat transplants were excluded. Demographic, laboratory, and hospital course data were...

IntroductionSerum albumin’s association with liver transplant outcomes has been investigated with mixed findings. This study aimed to evaluate perioperative albumin level, independently and as part of the albumin–bilirubin (ALBI) grade, as a predictor of post-liver transplant hospital and intensive care unit (ICU) length of stay (LOS).MethodsAdult liver-only transplant recipients at our institution from September 2011 to May 2019 were included in this retrospective study. Repeat transplants were excluded. Demographic, laboratory, and hospital course data were...

Massive uterine bleeding occurring after delivery is in most cases unpredictable and can have fatal consequences. This article presents the technique of combining the twisting of uterus on a 90° rotation on its axis and positioning a sling around the cervix, allowing to decrease incoming blood flow from uterine and ovarian arteries. The aim of this easy-to-use procedure is to enable surgeons and anaesthesiologists to respectively ensure the presence of an experienced surgeon and to...

This study aimed to assess satisfaction of patients affected by various fluid regimes during uncomplicated labor; to identify factors possibly associated with the level of satisfaction; to compare obstetrical and neonatal outcomes between the intervention groups. Between October and December 2014, 40 women were included in the study set at the Poitiers University Hospital, France. Women were randomly allocated to two study arms: 20 to strict and 20 to liberal fluid regime group. Women’s satisfaction...

The intrinsic connectivity of the salience network (SN) plays an important role in social behavior, however the directional influence that individual nodes have on each other has not yet been fully determined. In this study, we used spectral Dynamic Causal Modeling to characterize the effective connectivity patterns in the SN for 44 healthy older adults and for 44 patients with behavioral variant frontotemporal dementia (bvFTD) who have focal SN dysfunction. We examined the relationship of...

Background: Little is known about publication agreements between industry and academic investigators in trial protocols and the consistency of these agreements with corresponding statements in publications. We aimed to investigate (i) the existence and types of publication agreements in trial protocols, (ii) the completeness and consistency of the reporting of these agreements in subsequent publications, and (iii) the frequency of co-authorship by industry employees. Methods and Findings: We used a retrospective cohort of randomized clinical...

Additional file 2. SPIRIT checklist

Abstract Background Quality and reproducibility of radiomics studies are essential requirements for the standardisation of radiomics models. As recent data-driven respiratory gating (DDG) [18F]-FDG has shown superior diagnostic performance in lung cancer, we evaluated the impact of DDG on the reproducibility of radiomics features derived from [18F]-FDG PET/CT in comparison to free-breathing flow (FB) imaging. Methods Twenty four lung nodules from 20 patients were delineated. Radiomics features were derived on FB flow PET/CT and on...

Additional file 3: Fig. S3. Principal component analysis (PCA) of combined genotyping data. A) PCA plot of the first ten PCs of the genotyping data. Samples are colored by cohort. B) Histogram explaining the variance of each PC component. In the histogram, the variance explained by each eigenvalue is labeled on top.