Additional file 2. SPIRIT checklist

Abstract Background Surgery and radiotherapy are well-established standards of care for unilateral stage 0 and I early-stage glottic cancer (ESGC). Based on comparative studies and meta-analyses, functional and oncological outcomes after both treatment modalities are similar. Historically, radiotherapy (RT) has been performed by irradiation of the whole larynx. However, only the involved vocal cord is being treated with recently introduced hypofractionated concepts that result in 8 to 10-fold smaller target volumes. Retrospective data argues for...

Additional file 3. Differences and concordance among free-breathing and data-driven gating PET/CT for all radiomics features calculated separately based on pulmonary lesions localisation. The relative difference in percentage (DIFF%) and the concordance bias coefficient (Cb) are presented for each of the 141 radiomics features derived separately on each group “superior” and “inferior” depending on their anatomical localisation: lesions in the superior lobes versus the inferior regions. Non-reproducible features are marked with a star.

Supplemental material, sj-pdf-3-pal-10.1177_08258597221138674 for Clinical Practice Guidelines on Palliative Sedation Around the World: A Systematic Review by Martyna Tomczyk, Cécile Jaques and Ralf J. Jox in Journal of Palliative Care

Supplemental material, sj-pdf-4-pal-10.1177_08258597221138674 for Clinical Practice Guidelines on Palliative Sedation Around the World: A Systematic Review by Martyna Tomczyk, Cécile Jaques and Ralf J. Jox in Journal of Palliative Care

Supplemental material, sj-pdf-5-pal-10.1177_08258597221138674 for Clinical Practice Guidelines on Palliative Sedation Around the World: A Systematic Review by Martyna Tomczyk, Cécile Jaques and Ralf J. Jox in Journal of Palliative Care

Supplemental material, sj-pdf-5-pal-10.1177_08258597221138674 for Clinical Practice Guidelines on Palliative Sedation Around the World: A Systematic Review by Martyna Tomczyk, Cécile Jaques and Ralf J. Jox in Journal of Palliative Care

Supplemental material, sj-pdf-15-pal-10.1177_08258597221138674 for Clinical Practice Guidelines on Palliative Sedation Around the World: A Systematic Review by Martyna Tomczyk, Cécile Jaques and Ralf J. Jox in Journal of Palliative Care

This study aimed to assess satisfaction of patients affected by various fluid regimes during uncomplicated labor; to identify factors possibly associated with the level of satisfaction; to compare obstetrical and neonatal outcomes between the intervention groups. Between October and December 2014, 40 women were included in the study set at the Poitiers University Hospital, France. Women were randomly allocated to two study arms: 20 to strict and 20 to liberal fluid regime group. Women’s satisfaction...

IDH1/2 mutations, intervening in epigenetic procedures, are frequently encountered in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Knowledge of the genetics, immunophenotypes, and mutational kinetics of IDH1/2-mutated AML can contribute to the understanding of AML clonal architecture and inform therapeutics and monitoring. We retrospectively analyzed 50 IDH1/2-mutated AML/MDS-EB cases of our institution, to identify recurrent co-mutations, immunophenotypes, patterns of co-variance of IDH1/2 allele burdens with those of recurrent co-mutations, frequency of persistent IDH1/2 mutation...

Candida species are the most commonly isolated opportunistic fungal pathogens in humans. Candida albicans causes most of the diagnosed infections, closely followed by Candida glabrata. C. albicans is well studied, and many genes have been shown to be important for infection and colonization of the host. It is however less clear how C. glabrata infects the host. With the help of fungal RNA enrichment, we here investigated for the first time the transcriptomic profile of...

Additional file 1: Supplementary Table 1. Characteristics of the final cohort were compared with the excluded patients.

Additional file 1: Table 1. Participant characteristics. Figure 1. CONSORT flow diagram. Figure 2. Psychopathology and family burden. Figure 3. Response status at 16 weeks. Figure 4. Negative effects questionnaire. Supplemental Table 1. Detailed comorbidities. Supplemental Table 2. Psychopathology and family burden. Supplemental Table 3. Kidscreen-52. Supplemental Timeline. Supplemental Assumptions.