Supplementary information files for: Data-driven surrogate modelling and multi-variable optimization of trickle bed and packed bubble column reactors for CO2 capture via enhanced weathering Enhanced weathering (EW) of minerals could potentially absorb atmospheric CO2 at gigaton scale per year and store it as bicarbonate and carbonate in the ocean. However, this process must be accelerated by engineered reactors, in which optimal reaction conditions maximise the CO2 capture rate and minimise the energy and water consumption....

Supplement 1-Phase diagram of BIC

Additional file 2.

Additional file 1. Supplementary studies on the mechanisms of ALKBH5 on BTB integrity and list of antibodies used in this study.

Abstract Background The biological phenotype of tumours evolves during neoadjuvant chemotherapy (NAC). Accurate prediction of pathological complete response (pCR) to NAC in the early-stage or posttreatment can optimize treatment strategies or improve the breast-conserving rate. This study aimed to develop and validate an autosegmentation-based serial ultrasonography assessment system (SUAS) that incorporated serial ultrasonographic features throughout the NAC of breast cancer to predict pCR. Methods A total of 801 patients with biopsy-proven breast cancer were retrospectively...

Additional file 2. Bioinformatic analysis results of m6A-seq data after sliencing Alkbh5 in TM4 cell line.

Supplemental Material for A novel strategy to reduce the recirculation of venovenous extracorporeal membrane oxygenation: Inferior vena cava closure technology by Liusheng Hou, Jianwei Li, Wanyi Wang, Hongkai Liang, Jian Zhang, Binfei Li and Yuan Yong in Perfusion

Abstract Background It is highly desirable to develop new therapeutic strategies for gastric cancer given the low survival rate despite improvement in the past decades. Cadherin 17 (CDH17) is a membrane protein highly expressed in cancers of digestive system. Nanobody represents a novel antibody format for cancer targeted imaging and drug delivery. Nanobody targeting CHD17 as an imaging probe and a delivery vehicle of toxin remains to be explored for its theragnostic potential in gastric...

Abstract Background It would be very helpful to stratify patients and direct patient selection if risk factors for quality of life were identified in a particular population. Nonetheless, it is still challenging to forecast the health-related quality of life among individuals with spinal metastases. The goal of this study was to stratify patient’s populations for whom the assessment of quality of life should be encouraged by developing and validating a nomogram to predict the quality...

Additional file 1. The details of algorithm design, network training and testing.

Monocarboxylate transporters (MCTs) play vital roles in carbon source assimilation, drug resistance and virulence. However, the underlying function of MCTs in fungal pathogenesis and development has not been investigated in detail. In this study, we identified and characterized the monocarboxylate transporter gene MCT1 of Colletotrichum gloeosporioides, which is the causal agent of Glomerella leaf spot of apple. Mct1 is localized to the mitochondria and may mediate the uptake of lactate to the cell. However, MCT1...

Additional file 2: Table S2. Differentially expressed genes.

No description supplied

A new naphthoquinone, patulumnaphthoquinone A (1) and three new glycosides, patulumside B (2), patulumside C (3) and patulumside D (4) were isolated from the 30% ethanol extract of the fresh ripe fruits of Hypericum patulum Thunb. using column chromatography techniques. The structures of these compounds including absolute configurations were elucidated on the basis of HRESIMS, NMR spectroscopic analyses, calculated electronic circular dichroism spectra and comparison with the literatures.

Additional file 3: Table S3. The genes corresponding to the 21 significant pathways.

Detailed discussions of Eqs. (7) and (8) in the paper are demonstrated

Imaging systems consisting of flat phase element such as diffractive optical element, holographic optical element, and metasurface have important applications in many fields. However, there is still a lack of generalized and efficient design methods of these systems, especially for systems with nonsymmetric configurations. We proposed a design method of imaging system consisting of flat phase elements based on confocal properties. The description of the generalized phase function for realizing point-to-point stigmatic imaging are derived....

Brewing water plays a crucial role in flavor and potential healthy functions of tea infusion. In this study, seven water samples with different physicochemical properties were selected to brew green tea. Results showed that the brewing water with higher minerals level and pH value would reduce the yield of catechins in tea infusion, which in turn caused the decrease of antioxidant activity to a large extent. Besides, it was found that EGCG, as a major...

Ascorbic acid (AA) determination is of high importance in the diagnosis and treatment of diseases. Herein, we report a new ratiometric electrochemical sensor for ascorbic acid using a glassy carbon electrode (GCE) modified with a copper nanoparticle@resin nanosphere nanocomposite (CuNPs@RNS). The ratiometric strategy was established by immobilizing an internal reference (thionine) on the modified electrode using cyclic voltammetry (CV). The performance of the modified electrodes as well as the newly established ratiometric strategy was explored....

Supplemental material, sj-pdf-1-ajs-10.1177_03635465231152884 for Bony Remodeling of Adolescent Displaced Clavicle Fractures: A FACTS Study by Andrew T. Pennock, Tracey P. Bastrom, Kelly E. Boutelle, Alyssa N. Carroll, Eric W. Edmonds, Jeffrey J. Nepple, Samuel G. Polinsky, David D. Spence, Benton E. Heyworth, Crystal Perkins, Samuel C. Willimon, Donald S. Bae, Michael T. Busch, Henry B. Ellis, Katelyn Hergott, Mininder S. Kocher, Ying Li, Nirav K. Pandya, Coleen S. Sabatini and Philip L. Wilson in The...

The mitochondrial genome of Parasitus fimetorum was sequenced to study the Parasitidae tRNA gene secondary structure in Parasitiformes. tRNAscan-SE and ARWEN identified and inferred the secondary structures of 22 tRNA genes of Parasitus fimetorum, which were compared to 22 tRNA genes in sequenced Parasitidae mitochondrial genomes. The results showed that most tRNA genes of Parasitidae had a typical cloverleaf secondary structure; the base substitutions or mismatches occurred during the folding process, and the stem region...

As a type of lung cancer, non-small cell lung cancer (NSCLC) has the characteristics of high mortality and high recurrence rate, which poses a great threat to human life and health. Due to the high risk of surgical treatment and the slow recovery of wounds, non-coding RNAs, especially lncRNAs are used as new potential clinical prognostic markers to prevent and treat cancer in advance. This study aims to explore the role of FAM138B in NSCLC...

Myotubularin related protein 7 (MTMR7), a key member of the MTMR family, depicts phosphatase activity and is involved in myogenesis and tumor growth. We have previously identified MTMR7 in the proteomic profile of mouse spermatogonial stem cell (SSC) maturation and differentiation, implying that MTMR7 is associated with neonatal testicular development. In this study, to further explore the distribution and function of MTMR7 in mouse testis, we studied the effect of Mtmr7 knockdown on neonatal testicular...

Breast cancer remains a general-threat event in the health of women. Currently, increasing records indicate that long non-coding RNA maternally expressed 3 (MEG3) plays a central role in breast cancer. The current research focused on the function of MEG3 in paclitaxel (PTX)-resistance and human breast cancer growth. Levels of MEG3, microRNA (miR)-4513, and phenazine biosynthesis-like domain-containing protein (PBLD) were evaluated using quantitative real-time polymerase chain reaction (qRT-PCR) or western blot assays. 3-(4.5-dimethylghiazol-2-yl)-2,5-diphenyltetrazolium Bromide (MTT) assay...

ObjectiveThis study aims to compare the efficacy and safety of activated recombinant factor VII (rFVIIa) and prothrombin complex concentrate (PCC) in the treatment of bleeding complications following surgery requiring cardiopulmonary bypass (CPB) in children.Design/MethodsThis is a retrospective chart review of a single institution comprising patients aged 0 to 18 years old with congenital heart disease. Patients must have received either PCC or rFVIIa after coming off CPB. Our primary efficacy endpoint is time in the...