1,037 Works
Additional file 14 of Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)
Bing Zhang, Zhuoting Chen, Qixue Sun & Jianxiu Liu
Additional file 14: Table S7: Phosphoproteins and phosphopeptides previously identified in fast growing bermudagrass stolons.
A new polysaccharide from leaves of Sabia parviflora
Sijing Wu, Hui Li, Manshu Li, Bang Xu, Chengxiong Liu & Kun Zou
A new polysaccharide (SPT1) was isolated from Sabia parviflora Wall. ex Roxb., and the structure was identified by GPC, 1D and 2D NMR spectroscopy, SEM and AFM. The results showed that the average molecular weight (Mn) of SPT1 was 4.057 × 103 Da, and it was composed of α-glucose with a connection mode of 1→6. The SEM showed that the particle size of SPT1 was 1–200 μm and there were small gaps between the crystals....
A new polysaccharide from leaves of Sabia parviflora
Sijing Wu, Hui Li, Manshu Li, Bang Xu, Chengxiong Liu & Kun Zou
A new polysaccharide (SPT1) was isolated from Sabia parviflora Wall. ex Roxb., and the structure was identified by GPC, 1D and 2D NMR spectroscopy, SEM and AFM. The results showed that the average molecular weight (Mn) of SPT1 was 4.057 × 103 Da, and it was composed of α-glucose with a connection mode of 1→6. The SEM showed that the particle size of SPT1 was 1–200 μm and there were small gaps between the crystals....
Associations of lipid measures with total occlusion in patients with established coronary artery disease: a cross-sectional study
Tianyu Li, Deshan Yuan, Peizhi Wang, Sida Jia, Ce Zhang, Pei Zhu, Ying Song, Xiaofang Tang, Xueyan Zhao, Zhan Gao, Yuejin Yang, Runlin Gao, Bo Xu & Jinqing Yuan
Abstract Background Total occlusion is the most severe coronary lesion, indicating heavy ischemic burden and poor prognosis. The lipid profile is central to the development of atherosclerotic coronary lesions. Evidence on the optimal lipid measure to be monitored and managed in patients with established coronary artery disease (CAD) is inconclusive. Methods Total cholesterol (TC), total triglyceride (TG), low-density lipoprotein cholesterol (LDL-c), nonhigh-density lipoprotein cholesterol (non-HDL-c), lipoprotein (a) [Lp(a)], apolipoprotein B (apoB), non-HDL-c/HDL-c, and apoB/apoA-1 were...
sj-docx-3-cre-10.1177_02692155221135729 - Supplemental material for Effect of respiratory muscle training in patients with chronic kidney disease: A systematic review and meta-analysis of randomized controlled trials
Fan Zhang, Hui Wang, Yan Bai, Liuyan Huang & Huachun Zhang
Supplemental material, sj-docx-3-cre-10.1177_02692155221135729 for Effect of respiratory muscle training in patients with chronic kidney disease: A systematic review and meta-analysis of randomized controlled trials by Fan Zhang, Hui Wang, Yan Bai, Liuyan Huang and Huachun Zhang in Clinical Rehabilitation
Effect of respiratory muscle training in patients with chronic kidney disease: A systematic review and meta-analysis of randomized controlled trials
Fan Zhang, Hui Wang, Yan Bai, Liuyan Huang & Huachun Zhang
ObjectiveThis systematic review and meta-analysis aimed to evaluate the effect of respiratory muscle training on respiratory muscle strength, lung function, cardiopulmonary fitness, and quality of life for chronic kidney disease patients.MethodsPubMed, Embase, Web of Science Core Collection, and Cochrane Central Register of Controlled Trials published randomized controlled trials that evaluated the effect of respiratory muscle training for chronic kidney disease patients from inception to December 2021, and rerun on September 2022. The quality of included...
Data for: Both Conifer II and Gnetales are characterized by a high frequency of ancient mitochondrial gene transfer to the nuclear genome
Sheng-Long Kan, Ting-Ting Shen, Jin-Hua Ran & Xiao-Quan Wang
Background: Mitochondrial gene transfer/loss is common in land plants, and therefore the fate of missing mitochondrial genes has attracted more and more attention. The gene content of gymnosperm mitochondria varies greatly, supplying a system for studying the evolutionary fate of missing mitochondrial genes. Results: Here we studied the tempo and pattern of mitochondrial gene loss/transfer in gymnosperms represented by all 13 families, using high-throughput sequencing of both DNA and cDNA. All 41 mitochondrial protein-coding genes...
The predictive value of diabetic retinopathy on subsequent diabetic nephropathy in patients with type 2 diabetes: a systematic review and meta-analysis of prospective studies
Yu Li, Xiaoxuan Su, Qing Ye, Xiaodan Guo, Bo Xu, Tianjun Guan & Anqun Chen
This systematic review and meta-analysis aimed to assess the predictive value of diabetic retinopathy (DR) on further diabetic nephropathy (DN) risk in patients with type 2 diabetes (T2D) based on the prospective cohort studies. PubMed, Embase, and the Cochrane Library were systematically searched for eligible prospective cohort studies through March 2020. The predictive value of DR was assessed using sensitivity, specificity, positive likelihood ratio (PLR) and negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and...
Construction of a novel risk model based on the random forest algorithm to distinguish pancreatic cancers with different prognoses and immune microenvironment features
Yalan Lei, Rong Tang, Jin Xu, Bo Zhang, Jiang Liu, Chen Liang, Qingcai Meng, Jie Hua, Xianjun Yu, Wei Wang & Si Shi
Immune-related long noncoding RNAs (irlncRNAs) are actively involved in regulating the immune status. This study aimed to establish a risk model of irlncRNAs and further investigate the roles of irlncRNAs in predicting prognosis and the immune landscape in pancreatic cancer. The transcriptome profiles and clinical information of 176 pancreatic cancer patients were retrieved from The Cancer Genome Atlas (TCGA). Immune-related genes (irgenes) downloaded from ImmPort were used to screen 1903 immune-related lncRNAs (irlncRNAs) using Pearson’s...
Alterations of oral microbiota in patients with panic disorder
Zunli Xie, Weiqing Jiang, Mingzhu Deng, Wei Wang, Xian Xie, Xia Feng, Yinping Shi, Xueyan Zhang, Dong Song, Ziyu Yuan & Yonggang Wang
The main characteristics of panic disorder (PD) include recurrent panic attacks and persistent worry, accompanied by other physical and cognitive symptoms. While recent studies have revealed that gut bacteria play an important role in anxiety and depression, little is known about the relationship between oral microbiota and PD. Therefore, the objective of this study was to explore a possible correlation between oral microbiota and PD. We conducted 16S rRNA sequencing to compare differences in the...
Long non-coding RNA LINC00649 regulates YES-associated protein 1 (YAP1)/Hippo pathway to accelerate gastric cancer (GC) progression via sequestering miR-16-5p
Hongyan Wang, Xin Di, Yingjie Bi, Shidong Sun & Tao Wang
Although long non-coding RNA (LncRNA) LINC00649 is reported to be closely associated with acute myeloid leukemia (AML), prostate cancer and colorectal cancer, its role in regulating other types of cancer, such as gastric cancer (GC), has not been studied. This study analyzed the expression status of LINC00649 in GC tissues and cells by performing Real-Time qPCR analysis, and we found that LINC00649 tended to be enriched in cancerous tissues and cells but not in their...
A medication-wide association study to identify medications associated with incident clinically significant diabetic retinopathy
Ruilin Xiong, Wei Wang, Xianwen Shang, Yixiong Yuan, Yifan Chen, Lei Zhang, Katerina V Kiburg, Zhuoting Zhu & Mingguang He
Background:Diabetic retinopathy, a common microvascular complication of diabetes mellitus, is one of the leading causes of vision loss worldwide. Although some oral drugs have been suggested to affect the risk of diabetic retinopathy, systematic evaluation about the associations between medications and diabetic retinopathy is still absent.Objective:To comprehensively investigate associations of systemic medications with incident clinically significant diabetic retinopathy (CSDR).Design:Population-based cohort study.Methods:From 2006 to 2009, more than 26 000 participants residing in New South Wales were...
A medication-wide association study to identify medications associated with incident clinically significant diabetic retinopathy
Ruilin Xiong, Wei Wang, Xianwen Shang, Yixiong Yuan, Yifan Chen, Lei Zhang, Katerina V Kiburg, Zhuoting Zhu & Mingguang He
Background:Diabetic retinopathy, a common microvascular complication of diabetes mellitus, is one of the leading causes of vision loss worldwide. Although some oral drugs have been suggested to affect the risk of diabetic retinopathy, systematic evaluation about the associations between medications and diabetic retinopathy is still absent.Objective:To comprehensively investigate associations of systemic medications with incident clinically significant diabetic retinopathy (CSDR).Design:Population-based cohort study.Methods:From 2006 to 2009, more than 26 000 participants residing in New South Wales were...
Characterization of quality differences of Ophiopogonis Radix from different origins by TLC, HPLC, UHPLC-MS and multivariate statistical analyses
Ling Jiang, Yixing Qiu, Zhuliang Chen, Lu Luo, Hongxia Tang, Xudong Zhou, Hanwen Yuan, Wei Wang & Pingan Liu
Ophiopogonis Radix is normally used as a traditional medicine and healthy food in China. Thin-layer chromatography (TLC), total saponin content analysis, high-performance liquid chromatographic (HPLC) fingerprinting, ultra-high-performance liquid chromatographic (UHPLC) tandem mass (MS) spectra and multivariate statistical analyses were used to analyze differences in quality of Ophiopogonis Radix from three main producing areas in China. The TLC spots of samples obtained from Zhejiang were clearer and darker than samples from Sichuan and Shandong. Additionally, HPLC...
The estimation of protein equivalents of total nitrogen in Chinese CAPD patients: an explanatory study
Chunyan Su, Tao Wang, Peiyu Wang, Xinhong Lu & Wen Tang
The protein equivalent of total nitrogen appearance (PNA) formula, based on the urea nitrogen appearance (UNA), is popularly used by stable continuous ambulatory peritoneal dialysis (CAPD) patients to estimate dietary daily protein intake (DPI). However, we found that the estimated DPI was higher than that directly evaluated from the dietary records of most of our CAPD patients. Therefore, in the present study, we tried to determine possible bias in PNA estimation by UNA with a...
sj-docx-1-taj-10.1177_20406223231156826 – Supplemental material for Characterization of serum polyunsaturated fatty acid profile in patients with inflammatory bowel disease
Jingjing Jiang, Lu Chen, Rui Sun, Ting Yu, Shuyu Jiang & Hong Chen
Supplemental material, sj-docx-1-taj-10.1177_20406223231156826 for Characterization of serum polyunsaturated fatty acid profile in patients with inflammatory bowel disease by Jingjing Jiang, Lu Chen, Rui Sun, Ting Yu, Shuyu Jiang and Hong Chen in Therapeutic Advances in Chronic Disease
Longitudinal association between dietary protein intake and survival in peritoneal dialysis patients
Shu-Hong Bi, Xiaoxiao Wang, Wen Tang, Tao Wang, Baohua Li & Chunyan Su
Decreased dietary protein intake (DPI) may lead to protein-energy malnutrition and may be associated with increased mortality risk. We hypothesized that longitudinal changes in dietary protein intake have independent associations with survival in peritoneal dialysis (PD) patients. 668 stable PD patients were selected in the study from January 2006 to January 2018 and were followed up until December 2019. Their three-day dietary records were collected at the baseline (the sixth month after PD) and thereafter...
Ginkgo biloba Golden Leaf Extract (GGLE) Inhibits Melanoma Cell Invasion and Angiogenesis Through Inhibition of Angiogenin
Ping Chen, Tao Wang & Qi Chen
The popular dietary supplements of Ginkgo biloba (Ginkgo) products have been reported to have anti-cancer activities in multiple cellular and animal studies, with the benefits yet to be proven with clinical trials. The mechanisms of action are not clear, forming a barrier to investigation in Gingko-specific benefits to cancer patients, especially when combined with other therapies. Here we reported on the discovery of a novel mechanism by which a Ginkgo golden leaf extract (GGLE) inhibited...
Ginkgo biloba Golden Leaf Extract (GGLE) Inhibits Melanoma Cell Invasion and Angiogenesis Through Inhibition of Angiogenin
Ping Chen, Tao Wang & Qi Chen
The popular dietary supplements of Ginkgo biloba (Ginkgo) products have been reported to have anti-cancer activities in multiple cellular and animal studies, with the benefits yet to be proven with clinical trials. The mechanisms of action are not clear, forming a barrier to investigation in Gingko-specific benefits to cancer patients, especially when combined with other therapies. Here we reported on the discovery of a novel mechanism by which a Ginkgo golden leaf extract (GGLE) inhibited...
Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques
Pingchao Li, Qian Wang, Yizi He, Chenchen Yang, Zhengyuan Zhang, Zijian Liu, Bo Liu, Li Yin, Yilan Cui, Peiyu Hu, Yichu Liu, Pingqian Zheng, Wei Wang, Linbing Qu, Caijun Sun, Suhua Guan, Liqiang Feng & Ling Chen
Prolonged infection and possible evolution of SARS-CoV-2 in patients living with uncontrolled HIV-1 infection highlight the importance of an effective vaccination regimen, yet the immunogenicity of COVID-19 vaccines and predictive immune biomarkers have not been well investigated. Herein, we report that the magnitude and persistence of antibody and cell-mediated immunity (CMI) elicited by an Ad5-vectored COVID-19 vaccine are impaired in SIV-infected macaques with high viral loads (> 105 genome copies per ml plasma, SIVhi) but...
Palladium-catalyzed cross-coupling of benzene sulfonhydrazides and benzyltrimethylammonium salts: Synthesis of diarylmethanes
Weijie Yu, Juelin Wan, Puqing Chen, Kuang Zhao, Haijin Huang, Tao Wang & Jin Luo
A palladium-catalyzed cross-coupling of benzene sulfonyl hydrazides with benzyltrimethylammonium salts via C–S bond and C–N bond cleavage is reported. This reaction proceeds under mild reaction conditions and provides a new strategy for the synthesis of various diarylmethanes with broad functional group tolerance in moderate to good yields.
AQUATIC SPORTS REHABILITATION ON FUNCTIONAL RECOVERY OF KNEE JOINT INJURY
Qin Li, Shan Chen, Yuanyuan Zang, Xiaoyan Zhang & Hong Chen
ABSTRACT Introduction Knee joint injury is a common sports injury and how to speed up the recovery process is a concern for all athletes. Objective Determine whether aquatic sports rehabilitation nursing can accelerate the rehabilitation process of knee joint injuries. Methods Thirty patients with knee ligament or meniscal injury were divided into an aquatic sports group and a control group. The control group assumed general recovery measures, while the aquatic exercise group was added another...
Identification of genetic biomarkers associated with pharmacokinetics and pharmacodynamics of apixaban in Chinese healthy volunteers
Guangyan Mu, Qiufen Xie, Zhiyan Liu, Hanxu Zhang, Xianmin Meng, Jinfang Song, Shuang Zhou, Zhe Wang, Zining Wang, Xia Zhao, Jie Jiang, Maoxing Liao, Jiachun Bao, Fan Zhang, Qian Xiang & Yimin Cui
Apixaban is a superior direct oral anticoagulant exihibiting interindividual variability in concentration and response in the real world. The present study aimed to identify genetic biomarkers associated with pharmacokinetics (PK) and pharmacodynamics (PD) of apixaban in healthy Chinese subjects. This multicenter study included 181 healthy Chinese adults taking a single dose of 2.5 mg or 5 mg apixaban and assessed their PK and PD parameters. Genome-wide single nucleotide polymorphism (SNP) genotyping was performed using the...
Identification of genetic biomarkers associated with pharmacokinetics and pharmacodynamics of apixaban in Chinese healthy volunteers
Guangyan Mu, Qiufen Xie, Zhiyan Liu, Hanxu Zhang, Xianmin Meng, Jinfang Song, Shuang Zhou, Zhe Wang, Zining Wang, Xia Zhao, Jie Jiang, Maoxing Liao, Jiachun Bao, Fan Zhang, Qian Xiang & Yimin Cui
Apixaban is a superior direct oral anticoagulant exihibiting interindividual variability in concentration and response in the real world. The present study aimed to identify genetic biomarkers associated with pharmacokinetics (PK) and pharmacodynamics (PD) of apixaban in healthy Chinese subjects. This multicenter study included 181 healthy Chinese adults taking a single dose of 2.5 mg or 5 mg apixaban and assessed their PK and PD parameters. Genome-wide single nucleotide polymorphism (SNP) genotyping was performed using the...
Convective heat transfer coefficient of steel member in localized fire condition
Jinggang Zhou, Xuanyi Zhou, Beihua Cong & Wei Wang
At present, values adopted from specifications are mostly used to define the convective heat transfer coefficient ch in localized fire researches. In this paper, the specific scenario of the steel column surrounded by fire plume is selected as a typical case to explore the surface ch change rules of the steel column. This paper conducts a two-way coupling simulation analysis of the fire and the thermal models by means of CFD codes. First, the validity...
Affiliations
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Institute of Botany1,037
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Shanghai Jiao Tong University857
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Chinese Academy of Medical Sciences & Peking Union Medical College750
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University of Chinese Academy of Sciences702
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Zhejiang University655
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Fudan University642
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Huazhong University of Science and Technology636
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Nanjing Medical University619
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Capital Medical University552
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Central South University531