683 Works

Additional file 6 of Evolution of the CBL and CIPK gene families in Medicago: genome-wide characterization, pervasive duplication, and expression pattern under salt and drought stress

Xiao-Xia Zhang, Xiao-Long Ren, Xiao-Tong Qi, Zhi-Min Yang, Xiao-Lei Feng, Tian Zhang, Hui-Jie Wang, Peng Liang, Qi-Ying Jiang, Wen-Jun Yang, Yuan Fu, Min Chen, Zhi-Xi Fu & Bo Xu
Additional file 6: Table S4. CIPK protein sequences used to build phylogenetic tree.

Additional file 8 of Evolution of the CBL and CIPK gene families in Medicago: genome-wide characterization, pervasive duplication, and expression pattern under salt and drought stress

Xiao-Xia Zhang, Xiao-Long Ren, Xiao-Tong Qi, Zhi-Min Yang, Xiao-Lei Feng, Tian Zhang, Hui-Jie Wang, Peng Liang, Qi-Ying Jiang, Wen-Jun Yang, Yuan Fu, Min Chen, Zhi-Xi Fu & Bo Xu
Additional file 8: Figure S3. Synteny analysis of CBL and CIPK genes among four allelic chromosomes in M. sativa spp. sativa. CBL genes are in red, and CIPK genes are in gray. Red lines represent the collinearity of duplicated CBL genes, and gray lines indicate the collinearity of duplicated CIPK genes. Four sets of chromosomes in chromosome circles are represented by four different colors, light green for the first set of chromosomes (MsaX.1), light blue...

Prognostic value of creatinine-to-cystatin c ratio in patients with type 2 diabetes mellitus: a cohort study

Wen Wei, Shanggang Li, Jin Liu, Yong Liu, Kaihong Chen, Shiqun Chen, Mei Tu & Hong Chen
Abstract Background The serum creatinine-to-cystatin C ratio (Scr/Scys) has been suggested as a surrogate marker of muscle mass and a predictor of adverse outcomes in many diseases. However, the prognostic value of Scr/Scys in patients with type 2 diabetes mellitus (T2DM) is unknown. The aim of this study is to assess the prognostic value of Scr/Scys in patients with T2DM. Methods In this retrospective observational study, we enrolled 3668 T2DM patients undergoing coronary angiography (CAG)....

Self-assembly of DNA nanostructure containing cell-specific aptamer as a precise drug delivery system for cancer therapy in non-small cell lung cancer

Ning Wang, Chang Yu, Tingting Xu, Dan Yao, Lingye Zhu, Zhifa Shen & Xiaoying Huang
Abstract Background As the most common subtype in lung cancer, the precise and efficient treatment for non-small cell lung cancer (NSCLC) remains an outstanding challenge owing to early metastasis and poor prognosis. Chemotherapy, the most commonly used treatment modality, is a difficult choice for many cancer patients due to insufficient drug accumulation in tumor sites and severe systemic side-effects. In this study, we constructed a cell-specific aptamer-modified DNA nanostructure (Apt-NS) as a targeting drug delivery...

Additional file 2 of STEAP3 can predict the prognosis and shape the tumor microenvironment of clear cell renal cell carcinoma

Jiyue Wu, Qing Bi, Xiang Zheng, Huawei Cao, Changzhen Hao, Zejia Sun & Wei Wang
Additional file 2: Table S2: Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways analysis of the STEAP3-related genes.

Additional file 1 of Self-assembly of DNA nanostructure containing cell-specific aptamer as a precise drug delivery system for cancer therapy in non-small cell lung cancer

Ning Wang, Chang Yu, Tingting Xu, Dan Yao, Lingye Zhu, Zhifa Shen & Xiaoying Huang
Additional file 1: Scheme S1. The self-assembly process from single-strand DNA to a structural unit. The detail base sequences of three single-strand DNA, including S6 (aptamer), PP (palindrome probe), and Linker, are displayed in the pattern diagram. Figure S1. 8% PAGE image showing the influence of palindrome sequences on the synthesis of DNA nanostructure. CP (common probe) was instead of PP (palindrome probe). C-NS represented the synthetic products from self-assembly system in the absence of...

Additional file 2 of Interaction of miR-200a-3p with YAP regulates cell proliferation and metastasis differentially in HPV-positive and HPV-negative cervical cancer cells

Hong Chen, Lingling Gu, Min Zhang, Huifen Chen, Hong Liao, Xueping Cao, Lu Yu & Jun Zhang
Additional file 2: Fig. 2H. Full-length blots in Figure 2H C33A (left) and Siha (right) cells. The red solid lines are the figures in the manuscript. Fig. 2J. Full-length blots in Figure 2J C33A (left) and Siha (right) cells. The red solid lines are the figures in the manuscript. Supplementary Fig. S2. Full-length blots in Supplementary Fig S2. The red solid lines are the figures in the manuscript.

Additional file 5 of Combining QTL mapping and RNA-Seq Unravels candidate genes for Alfalfa (Medicago sativa L.) leaf development

Xueqian Jiang, Xijiang Yang, Fan Zhang, Tianhui Yang, Changfu Yang, Fei He, Ting Gao, Chuan Wang, Qingchuan Yang, Zhen Wang & Junmei Kang
Additional file 5: Table S3. List of 2,061 up-regulated genes (‘sativa’ Vs ‘falcata’).

Additional file 6 of Combining QTL mapping and RNA-Seq Unravels candidate genes for Alfalfa (Medicago sativa L.) leaf development

Xueqian Jiang, Xijiang Yang, Fan Zhang, Tianhui Yang, Changfu Yang, Fei He, Ting Gao, Chuan Wang, Qingchuan Yang, Zhen Wang & Junmei Kang
Additional file 6: Table S4. List of 1,709 down-regulated genes (‘sativa’ Vs ‘falcata’).

Additional file 6 of Combining QTL mapping and RNA-Seq Unravels candidate genes for Alfalfa (Medicago sativa L.) leaf development

Xueqian Jiang, Xijiang Yang, Fan Zhang, Tianhui Yang, Changfu Yang, Fei He, Ting Gao, Chuan Wang, Qingchuan Yang, Zhen Wang & Junmei Kang
Additional file 6: Table S4. List of 1,709 down-regulated genes (‘sativa’ Vs ‘falcata’).

Additional file 7 of Combining QTL mapping and RNA-Seq Unravels candidate genes for Alfalfa (Medicago sativa L.) leaf development

Xueqian Jiang, Xijiang Yang, Fan Zhang, Tianhui Yang, Changfu Yang, Fei He, Ting Gao, Chuan Wang, Qingchuan Yang, Zhen Wang & Junmei Kang
Additional file 7: Table S5. The information of the seven candidates.

Additional file 5 of Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop

Yongzhen Mo, Yumin Wang, Yian Wang, Xiangying Deng, Qijia Yan, Chunmei Fan, Shuai Zhang, Shanshan Zhang, Zhaojian Gong, Lei Shi, Qianjin Liao, Can Guo, Yong Li, Guiyuan Li, Zhaoyang Zeng, Weihong Jiang, Wei Xiong & Bo Xiang
Additional file 5: Supplemental Table 5. The potential circPVT1-interacting proteins in CNE2 cells identified by LC-MS/MS spectrometry after pull-down with the biontin-labeled circPVT1 probe.

Additional file 8 of Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop

Yongzhen Mo, Yumin Wang, Yian Wang, Xiangying Deng, Qijia Yan, Chunmei Fan, Shuai Zhang, Shanshan Zhang, Zhaojian Gong, Lei Shi, Qianjin Liao, Can Guo, Yong Li, Guiyuan Li, Zhaoyang Zeng, Weihong Jiang, Wei Xiong & Bo Xiang
Additional file 8: Supplemental Table 8. Clinicopathological data of 3 NPC tissues measured by RNA pull-down.

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop

Yongzhen Mo, Yumin Wang, Yian Wang, Xiangying Deng, Qijia Yan, Chunmei Fan, Shuai Zhang, Shanshan Zhang, Zhaojian Gong, Lei Shi, Qianjin Liao, Can Guo, Yong Li, Guiyuan Li, Zhaoyang Zeng, Weihong Jiang, Wei Xiong & Bo Xiang
Abstract Background Circular RNAs (circRNAs) act as gene expression regulators and are involved in cancer progression. However, their functions have not been sufficiently investigated in nasopharyngeal carcinoma (NPC). Methods The expression profiles of circRNAs in NPC cells within different metastatic potential were reanalyzed. Quantitative reverse transcription PCR and in situ hybridization were used to detect the expression level of circPVT1 in NPC cells and tissue samples. The association of expression level of circPVT1 with clinical...

Additional file 3 of Pseudomonas aeruginosa biofilm dispersion by the mouse antimicrobial peptide CRAMP

Yang Zhang, Peng Cheng, Shiyuan Wang, Xiaofen Li, Lianci Peng, Rendong Fang, Jing Xiong, Hui Li, Cui Mei, Jiye Gao, Zhenhui Song, Dengfeng Xu, Lizhi Fu, Chenghong Li, Xueqing Wu, Yuzhang He & Hongwei Chen
Additional file 3. Differentially expressed protein data.

sj-docx-1-isp-10.1177_00207640221141784 – Supplemental material for Social anxiety and depression symptoms in Chinese left-behind children after the lifting of COVID-19 lockdown: A network analysis

Kuiliang Li, Lei Ren, Lei Zhang, Chang Liu, Mengxue Zhao, Xiaoqing Zhan, Ling Li, Xi Luo & Zhengzhi Feng
Supplemental material, sj-docx-1-isp-10.1177_00207640221141784 for Social anxiety and depression symptoms in Chinese left-behind children after the lifting of COVID-19 lockdown: A network analysis by Kuiliang Li, Lei Ren, Lei Zhang, Chang Liu, Mengxue Zhao, Xiaoqing Zhan, Ling Li, Xi Luo and Zhengzhi Feng in International Journal of Social Psychiatry

Social anxiety and depression symptoms in Chinese left-behind children after the lifting of COVID-19 lockdown: A network analysis

Kuiliang Li, Lei Ren, Lei Zhang, Chang Liu, Mengxue Zhao, Xiaoqing Zhan, Ling Li, Xi Luo & Zhengzhi Feng
Background:Returning to social life after the lifting of COVID-19 lockdown may increase risk of social anxiety, which is highly co-morbid with depression. However, few studies have reported the association between them.Aims:To explore the complex relationship between social anxiety and depression symptoms in left-behind children after the lifting of the COVID-19 lockdown.Methods:A cross-sectional survey was conducted 6 months after the lockdown removal. A total of 3,107 left-behind children completed the survey with a mean age of...

Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease

Alexandra Pokhilko, Gaia Brezzo, Lahiru Handunnetthi, Raphael Heilig, Rachel Lennon, Colin Smith, Stuart M Allan, Alessandra Granata, Sanjay Sinha, Tao Wang, Hugh S Markus, Alexandra Naba, Roman Fischer, Tom Van Agtmael, Karen Horsburgh & M Zameel Cader
The extracellular matrix (ECM) is a key interface between the cerebrovasculature and adjacent brain tissues. Deregulation of the ECM contributes to a broad range of neurological disorders. However, despite this importance, our understanding of the ECM composition remains very limited mainly due to difficulties in its isolation. To address this, we developed an approach to extract the cerebrovascular ECM from mouse and human post-mortem normal brain tissues. We then used mass spectrometry with off-line high-pH...

Additional file 1 of Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus strains circulating in China from 2020 to 2021

Hong Zhuang, Leilei Sun, Xiaobo Wang, Min Xiao, Long Zeng, Haoran Wang, Hongfu Yang, Feng Lin, Chuang Wang, Liting Qin & Chengbao Wang
Additional file 1: Table S1. Information of PEDV strains obtained in this study. The information including strain name, collection date, collection region, S gene length, virus isolation and accession number.

Additional file 11 of Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)

Bing Zhang, Zhuoting Chen, Qixue Sun & Jianxiu Liu
Additional file 11: Table S4: Proteins with both acetylation and succinylation modifications.

Additional file 13 of Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)

Bing Zhang, Zhuoting Chen, Qixue Sun & Jianxiu Liu
Additional file 13: Table S6: KOBAS enrichment analysis of the succinylated proteins.

Additional file 14 of Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)

Bing Zhang, Zhuoting Chen, Qixue Sun & Jianxiu Liu
Additional file 14: Table S7: Phosphoproteins and phosphopeptides previously identified in fast growing bermudagrass stolons.

Self-Supervised Deep Learning Two-Photon Microscopy

Yuezhi He, Jing Yao, Lina Liu, Yufeng Gao, Jia Yu, Shiwei Ye, Hui Li & Wei Zheng
Artificial neural networks (ANNs) have shown great proficiency in transforming low-resolution microscopic images into high-resolution images. However, training data remains a challenge, as large-scale open-source databases of microscopic images are rare, particularly three-dimensional (3D) data. Moreover, the long training times and the need for expensive computational resources have become a burden to the research community. We introduced a deep-learning-based self-supervised volumetric imaging approach, which we termed “Self-Vision”. The self-supervised approach requires no training data, apart...

Integrated physiological and transcriptional dissection reveals the core genes involving nutrient transport and osmoregulatory substance biosynthesis in allohexaploid wheat seedlings under salt stress

Jun-fan Chen, Ying Liu, Tian-yu Zhang, Zheng-fu Zhou, Jin-yong Huang, Ting Zhou & Ying-peng Hua
Abstract Background Soil salinization has become a global problem restricting the seed yield and quality of crops, including wheat (Triticum aestivum L.). Salinity significantly alters plant morphology and severely disrupts physiological homeostasis. Salt tolerance of wheat has been widely studied whereas core ion transporters responsive to salt stress remain elusive. Results In this study, the wheat seedlings were subjected to salinity toxicity for morpho-physiological and transcriptomic analysis of wheat salt tolerance. There was a inversely...

Additional file 1 of Integrated physiological and transcriptional dissection reveals the core genes involving nutrient transport and osmoregulatory substance biosynthesis in allohexaploid wheat seedlings under salt stress

Jun-fan Chen, Ying Liu, Tian-yu Zhang, Zheng-fu Zhou, Jin-yong Huang, Ting Zhou & Ying-peng Hua
Additional file 1: Supplementary Table S1. Overview of the transcriptome sequencing data in this study. SupplementaryFigure S1. Expression correlation of in shoot and root samples ofwheat plants under salt stress. After7 d of wheat seed germination, the wheat seedlings were transferred to asolution containing 100 mM NaCl for 10 d. The heatmap showed the FPKM values ofgenes. SupplementaryFigure S2. The primary metabolic pathway enrichment map of DEGs inthe shoots of wheat plants under salt stress....

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