97 Works

Additional file 3 of Using a WeChat mini-program-based lactation consultant intervention to increase the consumption of mother’s own milk by preterm infants in the neonatal intensive care unit: a study protocol for a cluster randomized controlled trial

Jie Huo, Xinping Wu, Chuanli Gu, Zhangbin Yu, Jun Zhang, Xiaohui Chen, Jingai Zhu, Feng Liu, Beibei Liu, Qianqian Li & Shuping Han
Additional file 3.

Longitudinal Link Between Bullying Victimization and Bullying Perpetration: A Multilevel Moderation Analysis of Perceived School Climate

Keith L. Kaufman, David S. Lee, Jeffrey J. Milroy, Anita Raj, Qian Nie, Chunyan Yang, Meg Stomski, Zhanfeng Zhao, Zhaojun Teng & Cheng Guo
Existing theories and empirical studies have evidenced the association between bullying victimization and bullying perpetration. However, it is still unclear what factors mitigate or alter this risk linkage between bullying victimization and bullying perpetration to reduce bullying incidents. Guided by the social-ecological theory, this study used a longitudinal design to examine the moderating role of school climate in the association between bullying victimization and bullying perpetration at both the within-person and between-person levels among Chinese...

Fermitin family homolog 2 (Kindlin-2) affects vascularization during the wound healing process by regulating the Wnt/β-catenin signaling pathway in vascular endothelial cells

Jianghui Ying, Qiang Wang, Lu Lu, Jiaqi Liu, Rong Guo, Hao Hu, Hua Jiang & Fazhi Qi
Kindlin-2 is a member of the FERM-containing cytoskeletal protein family that regulates cell–matrix interactions. Previous studies have shown that Kindlin-2 recruits focal adhesion proteins and regulates integration by binding to the focal adhesion region of the integrin β-segment. Although Kindlin-2 has been reported to be involved in various skin diseases and many kinds of tumors, its role in the skin wound healing process remains unclear. The aim of the present study was to investigate the...

miR-199a-3p plays an anti-tumorigenic role in lung adenocarcinoma by suppressing anterior gradient 2

Hui Liu, Yanfeng Wang, Yi Wang, Daoyuan Wu & He Zhang
Previous studies have explored the association between protein-coding genes and microRNAs (miRNAs) in lung adenocarcinoma (LUAD). However, the influence of the miR-199a-3p/anterior gradient 2 (AGR2) axis in LUAD has not yet been fully explored. Therefore, this study aimed to examine the underlying roles of AGR2 and miR-199a-3p in the development of LUAD. The expression levels of miR-199a-3p and AGR2 in LUAD tissues and cells were detected via quantitative reverse transcription-polymerase chain reaction (qRT-PCR). A luciferase...

Celebrating the Work of J. Keith Murnighan

Donald Conlon, Max Bazerman, Deepak Malhotra & Madan Pillutla

Data from: Trait plasticity and tradeoffs shape intraspecific variation in competitive response in a foundation tree species

Olivia Cope, Richard Lindroth, Andrew Helm, Ken Keefover-Ring & Eric Kruger
The ability to tolerate neighboring plants (i.e., degree of competitive response) is a key determinant of plant success in high-competition environments. Plant genotypes adjust their functional trait expression under high levels of competition, which may help explain intraspecific variation in competitive response. However, the relationships between traits and competitive response are not well understood, especially in trees. In this study, we investigated among-genotype associations between tree trait plasticity and competitive response. We manipulated competition intensity...

The genetic architecture and evolution of life history divergence among perennials in the Mimulus guttatus species complex

Jennifer Coughlan, Maya Wilson Brown & John Willis
Ecological divergence is a main source of trait divergence between closely related species. Despite its importance in generating phenotypic diversity, the genetic architecture of most ecologically relevant traits is poorly understood. Differences in elevation can impose substantial selection for phenotypic divergence of both complex, correlated suites of traits (such as life history), as well as novel adaptations. Here, we use the Mimulus guttatus species complex to assess if divergence in elevation is accompanied by trait...

Connectivity and edge effects increase bee colonization in an experimentally fragmented landscape

Sean Griffin & Nick Haddad
Though landscape corridors increase dispersal of many animals and plants, it remains unknown whether increased dispersal increases colonization and establishment of new populations in connected fragments. Working in experimentally fragmented landscapes, we tested how two aspects of habitat fragments altered by corridors- connectivity and edge-to-area ratio- determine patterns of colonization by a solitary, cavity-nesting bee (Megachile rotundata). We found that though higher connectivity initially increased rates of nest-site occupation, higher edge-to-area ratio ultimately increased patch...

A General Approach to Recovering Market Expectations from Futures Prices with an Application to Crude Oil

Christiane Baumeister & Lutz Kilian
Futures markets are a potentially valuable source of information about price expectations. Exploiting this information has proved difficult in practice, because time-varying risk premia often render the futures price a poor measure of the market expectation of the price of the underlying asset. Although this expectation in principle may be recovered by adjusting the futures price by the estimated risk premium, a common problem is that there are as many measures of the market expectation...

Stickleback sensory morphology 2015 & 2017 measurements and analysis files

Robert Mobley
The peripheral sensory systems, whose morphological attributes help determine the acquisition of distinct types of information, provide a means to quantitatively compare multiple modalities of a species’ sensory ecology. We used morphological metrics to characterize multiple sensory modalities—the visual, olfactory, and mechanosensory lateral line sensory systems—for Gasterosteus aculeatus, the three‐spined stickleback, to compare how sensory systems vary in animals that evolve in different ecological conditions. We hypothesized that the dimensions of sensory organs and correlations...

Drought-driven wildfire impacts on structure and dynamics in a wet Central Amazonian forest

Aline Pontes-Lopes, Camila V. J. Silva, Jos Barlow, Lorena M. Rincón, Wesley A. Campanharo, Cássio A. Nunes, Catherine T. De Almeida, Celso H. L. Silva Junior, Henrique L. G. Cassol, Ricardo Dalagnol, Scott C. Stark, Paulo M.L.A. Graça & Luiz E. O. C. Aragão
While climate and human-induced forest degradation is increasing in the Amazon, fire impacts on forest dynamics remain understudied in the wetter regions of the basin, which are susceptible to large wildfires only during extreme droughts. To address this gap, we installed burned and unburned plots immediately after a wildfire in the northern Purus-Madeira (central Amazon) during the 2015 El-Niño. We measured all individuals ≥10cm in diameter at breast height, and conducted recensuses to track the...

Emergence rates of stink bugs and parasitoids under four heat wave conditions

Marianna Szucs & Olivia Simaz
Heat waves are becoming more frequent with climate change and their impact on lower and higher trophic levels can differ. Higher trophic levels, such as predators and parasitoids, are predicted to be more strongly affected by heat waves than herbivores because they may have smaller thermal windows and because of altered ecological interactions with lower trophic levels. We tested the effects of heat waves of varying intensity (36-42˚C), imposed for four hours during five consecutive...

Data from: Temporal dynamics of free‐living nitrogen fixation in the switchgrass rhizosphere

Darian Smercina, Sarah E. Evans, Maren L. Friesen & Lisa K. Tiemann
Here we present data associated with the manuscript, Temporal dyanmics of free-living nitrogen fixation in the switchgrass rhizosphere. Free-living nitrogen fixation (FLNF) represents an important terrestrial N source and is gaining interest for its potential to contribute plant available N to bioenergy cropping systems. Switchgrass, a cellulosic bioenergy crop, may be reliant on FLNF when particularly when grown on low N marginal lands. These potential contributions of FLNF to switchgrass and the controls on this...

Additional file 2 of Using a WeChat mini-program-based lactation consultant intervention to increase the consumption of mother’s own milk by preterm infants in the neonatal intensive care unit: a study protocol for a cluster randomized controlled trial

Jie Huo, Xinping Wu, Chuanli Gu, Zhangbin Yu, Jun Zhang, Xiaohui Chen, Jingai Zhu, Feng Liu, Beibei Liu, Qianqian Li & Shuping Han
Additional file 2.

Additional file 3 of Using a WeChat mini-program-based lactation consultant intervention to increase the consumption of mother’s own milk by preterm infants in the neonatal intensive care unit: a study protocol for a cluster randomized controlled trial

Jie Huo, Xinping Wu, Chuanli Gu, Zhangbin Yu, Jun Zhang, Xiaohui Chen, Jingai Zhu, Feng Liu, Beibei Liu, Qianqian Li & Shuping Han
Additional file 3.

Proteomic signatures predict preeclampsia in individual cohorts but not across cohorts – implications for clinical biomarker studies

Mohammad S. Ghaemi, Adi L. Tarca, Roberto Romero, Natalie Stanley, Ramin Fallahzadeh, Athena Tanada, Anthony Culos, Kazuo Ando, Xiaoyuan Han, Yair J. Blumenfeld, Maurice L. Druzin, Yasser Y. El-Sayed, Ronald S. Gibbs, Virginia D. Winn, Kevin Contrepois, Xuefeng B. Ling, Ronald J. Wong, Gary M. Shaw, David K. Stevenson, Brice Gaudilliere, Nima Aghaeepour & Martin S. Angst
Early identification of pregnant women at risk for preeclampsia (PE) is important, as it will enable targeted interventions ahead of clinical manifestations. The quantitative analyses of plasma proteins feature prominently among molecular approaches used for risk prediction. However, derivation of protein signatures of sufficient predictive power has been challenging. The recent availability of platforms simultaneously assessing over 1000 plasma proteins offers broad examinations of the plasma proteome, which may enable the extraction of proteomic signatures...

Resolution of acute cervical insufficiency after antibiotics in a case with amniotic fluid sludge

Lami Yeo, Roberto Romero, Tinnakorn Chaiworapongsa, Robert Para, Jeffrey Johnson, David Kmak, Eunjung Jung, Bo Hyun Yoon & Chaur-Dong Hsu
Cervical insufficiency generally refers to a condition in which there is mid-trimester cervical dilatation or protruding chorioamniotic membranes in the absence of uterine contractions. Such condition is a risk factor for spontaneous mid-trimester abortion or early preterm birth, and is associated with adverse neonatal outcomes. Both intra-amniotic infection and inflammation ascertained by amniocentesis have been identified in patients with cervical insufficiency, and are poor prognostic factors. A subset of patients with intra-amniotic inflammation will have...

Fermitin family homolog 2 (Kindlin-2) affects vascularization during the wound healing process by regulating the Wnt/β-catenin signaling pathway in vascular endothelial cells

Jianghui Ying, Qiang Wang, Lu Lu, Jiaqi Liu, Rong Guo, Hao Hu, Hua Jiang & Fazhi Qi
Kindlin-2 is a member of the FERM-containing cytoskeletal protein family that regulates cell–matrix interactions. Previous studies have shown that Kindlin-2 recruits focal adhesion proteins and regulates integration by binding to the focal adhesion region of the integrin β-segment. Although Kindlin-2 has been reported to be involved in various skin diseases and many kinds of tumors, its role in the skin wound healing process remains unclear. The aim of the present study was to investigate the...

Anti-neoplastic characteristics and potential targets of calycosin against bisphenol A-related osteosarcoma: bioinformatics analysis

Qijin Pan, Ka Wu, Jiachang Tan, Yu Li, Xiao Liang & Min Su
Environmentally, bisphenol A (BPA) is a well-known pollutant caused human health risk, including osteosarcoma (OS). OS, a deadly bone neoplasia, may occur in children and adults. However, the anti-OS pharmacotherapy prescribes limitedly in clinical practice. Interestingly, previous experimental evidences indicate calycosin-exerting potential anti-OS actions. Thus, in this report, we aimed to further characterize and detail the therapeutic targets and molecular mechanisms of calycosin-anti-BPA-related OS by using network pharmacology and molecular docking analyses. In results, the...

miR-199a-3p plays an anti-tumorigenic role in lung adenocarcinoma by suppressing anterior gradient 2

Hui Liu, Yanfeng Wang, Yi Wang, Daoyuan Wu & He Zhang
Previous studies have explored the association between protein-coding genes and microRNAs (miRNAs) in lung adenocarcinoma (LUAD). However, the influence of the miR-199a-3p/anterior gradient 2 (AGR2) axis in LUAD has not yet been fully explored. Therefore, this study aimed to examine the underlying roles of AGR2 and miR-199a-3p in the development of LUAD. The expression levels of miR-199a-3p and AGR2 in LUAD tissues and cells were detected via quantitative reverse transcription-polymerase chain reaction (qRT-PCR). A luciferase...

Uncovering antiobesity-related hypertension targets and mechanisms of metformin, an antidiabetic medication

Lu Yang, Jianxin Yang, Xiao Liang, Wenjun Huang, Xiaoxi Zhang & Rong Li
Metformin, a common clinical drug used to treat diabetes mellitus, is found with potential antiobese actions as reported in increasing evidences. However, the detailed mechanisms of metformin-antiobesity-related hypertension remain unrevealed. We have utilized the bioinformatics strategy, including network pharmacology and molecular docking analyses, to uncover pharmacological targets and molecular pathways of bioactive compounds against clinical disorders, such as cancers, coronavirus disease 2019. In this report, the in-silico approaches using network pharmacology and molecular docking was...

List of papers reviewed to uncover trends in the use of model systems in infectious disease ecology & evolutionary biology

Nina Wale
Ever since biologists began studying the ecology and evolution of infectious diseases (EEID), laboratory-based ‘model systems’ have been important for developing and testing theory. Yet what EEID researchers mean by ‘model systems’ and what they want from them is unclear. This uncertainty hinders our ability to maximally exploit these systems, identify knowledge gaps, and establish effective new model systems. Here, we borrow a definition of model systems from the biomolecular sciences to assess how EEID...

Anthropogenic noise alters parental behavior and nestling development, but not fledging condition

Meelyn Mayank Pandit, James Eapen, Gabriela Pineda-Sabilon, Margaret Caulfield, Alexander Moreno, Jay Wilhelm, Jessica Ruyle, Eli Bridge & Darren Proppe
Anthropogenic noise is a ubiquitous feature of the American landscape, and is a known stressor for many bird species, leading to negative effects in behavior, physiology, reproduction, and ultimately fitness. While a number of studies have examined how anthropogenic noise affects avian fitness, there are few that simultaneously examine how anthropogenic noise impacts the relationship between parental care behavior and nestling fitness. We conducted Brownian noise playbacks for six hours a day during the nesting...

Pastoralist cattle observations (vigilance and grouping behaviors)

Jacalyn Beck
Fear of predators fundamentally shapes the ecology of prey species and drives both inter- and intra-specific interactions. Extensive research has examined the consequences of predation risk from large carnivores on the behavior of wild ungulate prey species. However, many large carnivores not only hunt wild prey but also depredate domestic livestock, especially in pastoralist systems where livestock share land and resources with large carnivores. Northern Tanzania is a hotspot for human-carnivore conflict driven by livestock...

Gene modules lists of soybean in response to Fusarium virguliforme colonization

Amy Baetsen-Young, Huan Chen, Shin-Han Shiu & Brad Day
The broad host range of Fusarium virguliforme represents a unique comparative system to identify and define differentially-induced responses between an asymptomatic monocot host, maize (Zea mays), and a symptomatic eudicot host, soybean (Glycine max). Using a temporal, comparative transcriptome-based approach, we observed that early gene expression profiles of root tissue from infected maize suggest that pathogen tolerance coincides with the rapid induction of senescence dampening transcriptional regulators, including ANACs and Ethylene Responsive Factors. In contrast,...

Registration Year

  • 2021
    97

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Affiliations

  • Michigan State University
    97
  • Zhejiang University
    23
  • Huazhong University of Science and Technology
    21
  • Chinese Academy of Sciences
    20
  • West China Hospital of Sichuan University
    18
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    18
  • Shanghai Jiao Tong University
    16
  • Peking University
    15
  • Tongji University
    15
  • Fudan University
    14