53 Works

Data from: Estimating animal density without individual recognition using information derivable exclusively from camera traps

Yoshihiro Nakashima, Keita Fukasawa & Hiromitsu Samejima
1. Efficient and reliable methods for estimating animal density are essential to wildlife conservation and management. Camera trapping is an increasingly popular tool in this area of wildlife research , with further potential arising from technological improvements, such as video recording functions that allow for behavioural observation of animals. This information may be useful in the estimation of animal density, even without individual recognition. Although several models applicable to species lacking individual markings (i.e. unmarked...

Additional file 1 of Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis

Takayasu Suzuka, Takuya Kotani, Takashi Saito, Shogo Matsuda, Takako Sato & Tohru Takeuchi
Additional file 1. Experimental protocol. For induction of skin fibrosis, 8-week-old female Balb/c mice were subcutaneously injected with 100 μg/100 μL of bleomycin daily for 3 weeks. mASCs were administered 1 week after the start of bleomycin administration and evaluated at 3 weeks. mASCs: mouse adipose-derived mesenchymal stem cells.

Additional file 2 of Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis

Takayasu Suzuka, Takuya Kotani, Takashi Saito, Shogo Matsuda, Takako Sato & Tohru Takeuchi
Additional file 2. Experimental data. Genes of GREM-1 and IL-6 were not affected by hep-ASCs. For the skin mRNA expression levels of gremlin-1 (GREM-1), and interleukin (IL)-6 which may induce GREM-1, there was no significant difference between the groups. n = 7 in each group. Data are shown as mean ± SEM.

Additional file 2 of Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma

Taisuke Imamura, Yukiyasu Okamura, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Sumiko Ohnami, Takeshi Nagashima, Keiichi Hatakeyama, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama & Ken Yamaguchi
Additional file 2: Supplementary Table 1. Mutations identified in MUC16.

Additional file 1 of Visualization of clonal expansion after massive depletion of cells carrying the bovine leukemia virus (BLV) integration sites during the course of disease progression in a BLV naturally-infected cow: a case report

Susumu Saito, Kazuyoshi Hosomichi, Meripet Polat Yamanaka, Tetsuya Mizutani, Shin-nosuke Takeshima & Yoko Aida
Additional file 1. Probes for NGS and PCR primers.

Additional file 2 of Visualization of clonal expansion after massive depletion of cells carrying the bovine leukemia virus (BLV) integration sites during the course of disease progression in a BLV naturally-infected cow: a case report

Susumu Saito, Kazuyoshi Hosomichi, Meripet Polat Yamanaka, Tetsuya Mizutani, Shin-nosuke Takeshima & Yoko Aida
Additional file 2: Figure S1. Visualization of paired-end short read sequences of Stages I, II, and III mapped to the BLV reference FLK-BLV sequence (NCBI accession number EF600696). Horizontal lines in the schematic structure of the biotinylated probe targeting region at the top indicate biotinylated probes used in this study.

Data from: Sperm allocation in relation to female size in a semelparous salmonid

Yuya Makiguchi, Masaki Ichimura, Takenori Kitayama, Yuuki Kawabata, Takashi Kitagawa, Takahito Kojima & Trevor E. Pitcher
To maximize reproductive success, males have to adaptively tailor their sperm expenditure in relation to the quality of potential mates because they require time to replenish their sperm supply for subsequent mating opportunities. Therefore, in mating contexts where males must choose among females in a short period of time, as is the case with semelparous species (which die after one intensely competitive short duration breeding season), selection on sperm allocation can be expected to be...

Data from: Methods for invasive species control are transferable across invaded areas

Takashi Haramura, Michael R. Crossland, Hirohiko Takeuchi & Richard Shine
Cane Toads (Rhinella marina) are invasive pests in many parts of the world, including the Japanese island of Ishigaki. Extensive research in Australia has identified promising new methods for control, but also has shown that toads exhibit geographic variation in many traits (suggesting that methods developed in one location may not work in another). Can the approaches developed in Australia play a useful role for controlling this invasive species in Japan? Our experimental trials on...

Additional file 1 of Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma

Taisuke Imamura, Yukiyasu Okamura, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Sumiko Ohnami, Takeshi Nagashima, Keiichi Hatakeyama, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama & Ken Yamaguchi
Additional file 1: Supplementary Fig. 1. Mutation signature in the sample with multiple mutations. Supplementary Fig. 2. The distribution of TMB in HCCs. Supplementary Fig. 3. The mutational mapping of MMs in CTNNB1 and MUC16. Supplementary Fig. 4. Drug sensitivity screens in Cancer Cell Line Encyclopedia.

Additional file 2 of Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma

Taisuke Imamura, Yukiyasu Okamura, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Sumiko Ohnami, Takeshi Nagashima, Keiichi Hatakeyama, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama & Ken Yamaguchi
Additional file 2: Supplementary Table 1. Mutations identified in MUC16.

Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma

Taisuke Imamura, Yukiyasu Okamura, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Sumiko Ohnami, Takeshi Nagashima, Keiichi Hatakeyama, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama & Ken Yamaguchi
Abstract Background Multiple mutation (MM) within a single gene has recently been reported as a mechanism involved in carcinogenesis. The present study investigated the clinical significance of MMs in hepatocellular carcinoma (HCC). Methods Two hundred twenty-three surgically resected HCCs were subjected to gene expression profiling and whole-exome sequencing. Results MMs in individual genes were detected in 178 samples (MM tumors: 79.8%). The remaining samples all carried a single mutation (SM tumors: 20.2%). Recurrence-free survival in...

Additional file 2 of Clinical impact of cardiac magnetic resonance in patients with suspected coronary artery disease associated with chronic kidney disease (AQUAMARINE-CKD study): study protocol for a randomized controlled trial

Teruo Noguchi, Hideki Ota, Naoya Matsumoto, Yoshiaki Morita, Akira Oshita, Eiji Kawasaki, Tomohiro Kawasaki, Kensuke Moriwaki, Shingo Kato, Kazuki Fukui, Tomoya Hoshi, Hiroaki Watabe, Tomoaki Kanaya, Yasuhide Asaumi, Yu Kataoka, Fumiyuki Otsuka, Kensuke Takagi, Shuichi Yoneda, Kenichiro Sawada, Takamasa Iwai, Hideo Matama, Satoshi Honda, Masashi Fujino, Hiroyuki Miura, Kunihiro Nishimura … & Kei Takase
Additional file 2: Supplementary Table 1. Standardized protocol for non-contrast T1-weighted imaging to assess coronary plaques: recommended protocol for CMR coronary plaque imaging.

Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly

Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge & Naoki Morimoto
This study systematically and comprehensively analysed 129 thumb polydactylies in 122 patients using a duplicating range concept based on the level of skin and skeletal bifurcation. Numerical levels were defined along the longitudinal axis of the ulnar thumb duplicate from distal to proximal: level 0 (thumb tip) to level 6 (carpometacarpal joint). The relationships between duplication range and morphological parameters were evaluated. Nail asymmetry was associated with skin bifurcation levels 0 to 2. Proximal phalangeal...

sj-jpg-1-jhs-10.1177_17531934221126864 - Supplemental material for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly

Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge & Naoki Morimoto
Supplemental material, sj-jpg-1-jhs-10.1177_17531934221126864 for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly by Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge and Naoki Morimoto in Journal of Hand Surgery (European Volume)

Effectiveness and safety of the direct oral anticoagulant in acute distal deep vein thrombosis: From the prospective multicenter observational study, J’xactly, in Japan

Makoto Mo, Ikuo Fukuda, Mashio Nakamura, Norikazu Yamada, Morimasa Takayama, Hideaki Maeda, Takeshi Yamashita, Takanori Ikeda, Tsutomu Yamazaki, Yasuo Okumura & Atsushi Hirayama
ObjectivesWe assessed the effectiveness and safety of rivaroxaban in patients with isolated distal deep vein thrombosis (IDDVT).MethodsSymptomatic venous thromboembolism (VTE) and major bleeding were assessed.ResultsOf 1016 patients with acute symptomatic/asymptomatic DVT and/or pulmonary embolism treated with rivaroxaban, 288 had IDDVT and 294 had proximal DVT (pDVT). The IDDVT group had fewer patients on the higher rivaroxaban dose (30 mg/day) (42.7% vs. 66.0%) and a shorter treatment duration (135.5 vs 369.5 days) than the pDVT group....

Data from: Initial hydraulic failure followed by late-stage carbon starvation leads to drought-induced death in tree, Trema orientalis

Yuri Kono, Atsushi Ishida, Shin-Taro Saiki, Kenichi Yoshimura, Masako Dannoura, Kenichi Yazaki, Fuku Kimura, Jin Yoshimura & Shin-Ichi Aikawa
Drought-induced tree death has become a serious problem in global forest ecosystems. Two nonexclusive hypotheses, hydraulic failure and carbon starvation, have been proposed to explain tree die-offs. To clarify the mechanisms, we investigated the physiological processes of drought-induced tree death in saplings with contrasting Huber values (sapwood area/total leaf area). First, hydraulic failure and reduced respiration were found in the initial process of tree decline, and in the last stage carbon starvation leaded to tree...

sj-jpg-1-jhs-10.1177_17531934221126864 - Supplemental material for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly

Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge & Naoki Morimoto
Supplemental material, sj-jpg-1-jhs-10.1177_17531934221126864 for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly by Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge and Naoki Morimoto in Journal of Hand Surgery (European Volume)

sj-jpg-4-jhs-10.1177_17531934221126864 - Supplemental material for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly

Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge & Naoki Morimoto
Supplemental material, sj-jpg-4-jhs-10.1177_17531934221126864 for Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly by Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge and Naoki Morimoto in Journal of Hand Surgery (European Volume)

Additional file 2 of Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis

Takayasu Suzuka, Takuya Kotani, Takashi Saito, Shogo Matsuda, Takako Sato & Tohru Takeuchi
Additional file 2. Experimental data. Genes of GREM-1 and IL-6 were not affected by hep-ASCs. For the skin mRNA expression levels of gremlin-1 (GREM-1), and interleukin (IL)-6 which may induce GREM-1, there was no significant difference between the groups. n = 7 in each group. Data are shown as mean ± SEM.

Use of the duplication range concept for understanding morphology and predicting prognosis in thumb polydactyly

Susumu Saito, Aiko Makino, Hiroki Yamanaka, Itaru Tsuge & Naoki Morimoto
This study systematically and comprehensively analysed 129 thumb polydactylies in 122 patients using a duplicating range concept based on the level of skin and skeletal bifurcation. Numerical levels were defined along the longitudinal axis of the ulnar thumb duplicate from distal to proximal: level 0 (thumb tip) to level 6 (carpometacarpal joint). The relationships between duplication range and morphological parameters were evaluated. Nail asymmetry was associated with skin bifurcation levels 0 to 2. Proximal phalangeal...

Additional file 3 of Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma

Taisuke Imamura, Yukiyasu Okamura, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Sumiko Ohnami, Takeshi Nagashima, Keiichi Hatakeyama, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama & Ken Yamaguchi
Additional file 3: Supplementary Table 2. Gene expression raw data.

Additional file 3 of Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma

Taisuke Imamura, Yukiyasu Okamura, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Sumiko Ohnami, Takeshi Nagashima, Keiichi Hatakeyama, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama & Ken Yamaguchi
Additional file 3: Supplementary Table 2. Gene expression raw data.

Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma

Taisuke Imamura, Yukiyasu Okamura, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Sumiko Ohnami, Takeshi Nagashima, Keiichi Hatakeyama, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama & Ken Yamaguchi
Abstract Background Multiple mutation (MM) within a single gene has recently been reported as a mechanism involved in carcinogenesis. The present study investigated the clinical significance of MMs in hepatocellular carcinoma (HCC). Methods Two hundred twenty-three surgically resected HCCs were subjected to gene expression profiling and whole-exome sequencing. Results MMs in individual genes were detected in 178 samples (MM tumors: 79.8%). The remaining samples all carried a single mutation (SM tumors: 20.2%). Recurrence-free survival in...

Visualization of clonal expansion after massive depletion of cells carrying the bovine leukemia virus (BLV) integration sites during the course of disease progression in a BLV naturally-infected cow: a case report

Susumu Saito, Kazuyoshi Hosomichi, Meripet Polat Yamanaka, Tetsuya Mizutani, Shin-nosuke Takeshima & Yoko Aida
Abstract Bovine leukemia virus (BLV) infects cattle, integrates into host DNA as a provirus, and induces malignant B-cell lymphoma. Previous studies have addressed the impact of proviral integration of BLV on BLV-induced leukemogenesis. However, no studies have monitored sequential changes in integration sites in which naturally infected BLV individuals progress from the premalignant stage to the terminal disease. Here, we collected blood samples from a single, naturally infected Holstein cow at three disease progression stages...

Supplemental Material—Effectiveness and safety of the direct oral anticoagulant in acute distal deep vein thrombosis: From the prospective multicenter observational study, J’xactly, in Japan

Makoto Mo, Ikuo Fukuda, Mashio Nakamura, Norikazu Yamada, Morimasa Takayama, Hideaki Maeda, Takeshi Yamashita, Takanori Ikeda, Tsutomu Yamazaki, Yasuo Okumura & Atsushi Hirayama
Supplemental Material for Effectiveness and safety of the direct oral anticoagulant in acute distal deep vein thrombosis: From the prospective multicenter observational study, J’xactly, in Japan by Makoto Mo, Ikuo Fukuda, Mashio Nakamura, Norikazu Yamada, Morimasa Takayama, Hideaki Maeda, Takeshi Yamashita, Takanori Ikeda, Tsutomu Yamazaki, Yasuo Okumura, Atsushi Hirayama, and on behalf of the J’xactly Investigators in Phlebology.

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