Abstract Background In order to reduce work-related upper limb disorders, the Swedish Work Environment Authority introduced an occupational health surveillance targeting hand-intensive work. A process model, aimed at supporting the employers as well as the occupational health service provider (i.e., ergonomist) in the work process with the occupational health surveillance, was developed. The objective of this qualitative study was to explore ergonomists’ experiences of the execution of occupational health surveillance for hand-intensive work when following...

Additional file 2. Data base searches.

Additional file 3. Guidelines for data charting

Additional file 5. Table of included articles (author(s), year of publication, reference, country, aims and research questions, methodology, type of data material, length of data collection period, number of participants)

Low socioeconomic status based both on educational level and income has been associated with asthma and respiratory symptoms, but changes over time in these associations have rarely been studied. The aim was to study the associations between educational or income inequality and asthma and respiratory symptoms among women and men over a 20-year period in northern Sweden. The study was performed within the Obstructive Lung disease in Northern Sweden (OLIN) research program. Mailed questionnaire surveys...

We consider the model-free feature screening problem that aims to discard non-informative features before downstream analysis. Most of the existing feature screening approaches have at least quadratic computational cost with respect to the sample size n, thus may suffer from a huge computational burden when n is large. To alleviate the computational burden, we propose a scalable model-free sure independence screening approach. This approach is based on the so-called sliced-Wasserstein dependency, a novel metric that...

Social sustainability has increasingly become a goal for urban policy and planning, and for local and regional developmental strategies. Neighbourhoods are a common spatial scale for studying social sustainability and there is a growing focus on social sustainability in urban neighbourhoods for both researchers and policymakers. This paper is based on a qualitative case study of a neighbourhood defined by the municipality as at-risk of negative social development in a municipality in northern Sweden. The...

This study investigates the evolutionary history of Pinus densata on the Qinghai-Tibetan Plateau (QTP) and genomic heterogeneity across a zone of species transition to understand contemporary dynamics of selection and evolution of species barriers. We analyzed the genetic diversity in a range-wide collection of P. densata and representative populations of its progenitors P. tabuliformis and P. yunnanensis using 40,000 exome probe capture sequencing.

Supplemental material, sj-pdf-1-ijb-10.1177_13670069221139155 for A longitudinal study of episodic memory recall in multilinguals by Mariana Vega-Mendoza, Daniel Eriksson Sörman, Maria Josefsson and Jessica K. Ljungberg in International Journal of Bilingualism

Microspore transfers the developmental fate into embryogenesis in vitro regulated by determinant factors of stress-induced. However, the key regulators of microspore embryogenesis (ME) are still largely undiscovered to reveal the mechanism of cell fate transition. Here, we report that Phospholipase C (PLC) is involved at the early stages of ME in Nicotiana tabacum. NtPLC2/3/4 are expressed at the initial stages of ME. The expression levels of NtPLC2/3 are transient activated after 3 days in culture,...

Supplemental material, sj-docx-1-sph-10.1177_19417381221147305 for A Longitudinal Case-Control Study of a Female Athlete Preinjury and After ACL Reconstruction: Hop Performance, Knee Muscle Strength, and Knee Landing Mechanics by Josefine E. Naili, Jonas L. Markström and Charlotte K. Häger in Sports Health: A Multidisciplinary Approach

Additional file 3: Figure s2. Bland–Altman plots. Legend Bland–Altman plots illustrating the relationship between the difference between R1 (FE-PE2I) and F (H2O) relative regional cerebral blood flow (on the y-axis), and the mean of R1 and F (on the x-axis) in the frontal, parietal and temporal lobes and the cingulate cortex, the putamen and the caudate, respectively. The mean of the difference is indicated by the bold black line. The upper and lower limits of...

Metabarcoding of environmental DNA constitutes a state-of-the-art tool for environmental studies. One fundamental principle implicit in most metabarcoding studies is that individual sample amplicons can still be identified after being pooled with others – based on their unique combinations of tags – during the so-called demultiplexing step that follows sequencing. Nevertheless, it has been recognized that tags can sometimes be changed (i.e. tag jumping), which ultimately leads to sample crosstalk. Here, using four DNA metabarcoding...

Fast-adapting type 1 (FA-1) and slow-adapting type 1 (SA-1) first-order neurons in the human tactile system have distal axons that branch in the skin and form many transduction sites, yielding receptive fields with many highly sensitive zones or ‘subfields’. We previously demonstrated that this arrangement allows FA-1 and SA-1 neurons to signal the geometric features of touched objects, specifically the orientation of raised edges scanned with the fingertips. Here we show that such signaling operates...

Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular hallmarks of tumour hypoxia remain poorly understood, with limited comprehension of its associations with specific mutational processes, non-coding driver genes and evolutionary features. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we quantify hypoxia in 1188 tumours spanning...

Additional file 2: Figure s1. Correlation plots of R1 (FE-PE2I) and F (H2O): cingulate, putamen and caudate. Legend Right: Cingulate cortex, Middle: Putamen, Left: Caudate. Values are averaged over the left and right hemispheres. HC Healthy controls (open squares), Pat Patients (filled red dots).

Additional file 4: Table s1. Difference in rCBFR measured as F (H2O) and R1 (FE-PE2I) between patients and healthy controls (T-test results). Legend Measures are averaged left and right hemisphere rCBFR values. rCBFR: relative regional cerebral blood flow. HC Healthy controls; rCBFR relative regional cerebral blood flow. F relative regional cerebral blood flow measured with [15O]H2O PET. R1 relative regional cerebral blood flow measured with [18F]FE-PE2I.

Additional file 1: Table s3. Test of normally distributed differences between R1 and F. Legend R1 relative regional cerebral blood flow measured with [18F]FE-PE2I, F relative regional cerebral blood flow measured with [15O]H2O PET.

Supplemental material, sj-docx-1-tpp-10.1177_20451253231151514 for Incidence of hyperthyroidism in patients with bipolar or schizoaffective disorder with or without lithium: 21-year follow-up from the LiSIE retrospective cohort study by Ingrid Lieber, Michael Ott, Robert Lundqvist, Mats Eliasson and Ursula Werneke in Therapeutic Advances in Psychopharmacology

Background:Lithium-associated hyperthyroidism is much rarer than lithium-associated hypothyroidism. Yet, it may be of substantial clinical significance for affected individuals. For instance, lithium-associated hyperthyroidism could destabilise mood, mimic manic episodes and impact physical health. Only few studies have explored incidence rates of lithium-associated hyperthyroidism. Even fewer studies have compared incidence rates according to lithium exposure history.Objectives:To determine the impact of lithium treatment on the incidence rate of hyperthyroidism in patients with bipolar or schizoaffective disorder and...

This dataset contains the concentration of eleven antibiotics (trimethoprim, oxytetracycline, ciprofloxacin, azithromycin, cefotaxime, doxycycline, sulfamethoxazole, erythromycin, clarithromycin, ofloxacin, norfloxacin), three decongestants (naphazoline, oxymetazoline, xylometazoline) and the antiviral drug oseltamivir's active metabolite, oseltamivir carboxylate, measured at 21 locations within the River Thames catchment in England. The measurements were taken weekly during November 2009, once in March 2010 and once in May 2011, with the aim to quantify pharmaceutical usage during the influenza pandemic of 2009 and...

Additional file 2: Table S1. Proportion of repetitive elements in the genome. Table S2. Comparative analysis of repeat sequences in two species. Table S3. List of 41 TEs shared in the two species (copy number >500). Table S4. Annotations of Class I retrotransposon transcript (TPM>1). Table S5. Retrotransposon transcript quantification matrix (TPM normalization) of L. migratoria. Table S6. Retrotransposon transcript quantification matrix (TPM normalization) of A. rhodopa. Table S7. Abundance of piRNAs corresponding to 41...

To examine the association between surgical waiting times (SWTs) and all-cause mortality (ACM) in non-metastatic patients with RCC, in relation to tumour stage. This nation-wide population-based cohort study included 9,918 M0 RCC patients registered in the National Swedish Kidney Cancer Register, between 2009 and 2021, followed-up for ACM until 9 December 2021, and having measured SWTs. The associations between primarily SWTs from date of radiological diagnosis to date of surgery (WRS) and secondarily SWTs from...

Additional file 2: Supplementary tables and figures. Figure S1. Pearson correlation between the 117 original metabolites. Figure S2. Sensitivity analyses of mutually adjusted ORs for the overall associations and cancer type-specific deviations. Figure S3. Sensitivity analysis of mutually adjusted ORs for the overall associations and cancer type-specific deviations with or without excluding hormone users. Figure S4. p-values of tests for departure from linearity and effect modification by BMI. Figure S5. ORs for the overall associations...

The discovery of driver mutations is one of the key motivations for cancer genome sequencing. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we describe DriverPower, a software package that uses mutational burden and functional impact evidence to identify driver mutations in coding and non-coding sites within cancer whole genomes. Using a total of 1373 genomic features...