Additional file 2: Table S2.

Additional file 2: Table S2.

Additional file 3: Table S3.

Additional file 4: Table S4.

Abstract Background AU-rich elements (AREs) are located in the 3′UTRs of 22% of human mRNAs, including most transiently expressed inflammatory mediators. By default, AREs mark mRNAs for decay and translational inhibition, but this activity can be temporarily inhibited in case of infection to allow the onset of inflammation. Morbidity and mortality in COVID-19 patients have been associated with dysregulated inflammation, a process that may include aberrant ARE activity. Results RNA-seq data from available transcriptomic studies...

Background: Cases of undiagnosed pneumonia have emerged, and sequencing of respiratory samples indicated the presence of SARS-CoV-2 causing COVID-19. Patients with higher viral load and lower Ct values tend to have progressive disease and severe lung injury. The objective of this study is to describe the clinical manifestation and disease outcomes of COVID-19 patients in relation to their Ct values. Methods: A retrospective, single-center observational study was performed, including patients admitted to King Faisal Specialist...

Supplemental material, sj-docx-1-pch-10.1177_21501351221139834 for Does Secondary Antibiotic Prophylaxis Improve Clinical Outcomes in Adult Rheumatic Heart Disease Patients Post-Valve Replacement? by Abdulrazaq S Al-Jazairi, Ahlam M Althobaiti, Josef Marek, Edward B Devol, Zohair Al Halees, Dania Mohty and Bahaa M Fadel in World Journal for Pediatric and Congenital Heart Surgery

Additional file 1. List of KSA panel members.

Additional file 2. Prioritized questions for the adolopment of the 2021 American College of Rheumatology (ACR) Guideline for the Treatment of Rheumatoid Arthritis (RA) in Saudi Arabia.

Additional file 2. Prioritized questions for the adolopment of the 2021 American College of Rheumatology (ACR) Guideline for the Treatment of Rheumatoid Arthritis (RA) in Saudi Arabia.

Additional file 3. Evidence to Decision tables.

Proteus mirabilis is a gram-negative bacterium particularly known for its unique swarming ability. The swarming gives the bacteria ability to enhance adherence to the catheter surface and epithelium cells of the urethra to cause catheter associated urinary tract infections. P. mirabilis has evolved resistant to antibiotics. Additionally, there is an approved vaccine against P. mirabilis, thus demanding for identification of new vaccine targets. This gram-negative bacterium consists of 19,502 core proteins, out of which 19,063...

Lead (Pb) is a biologically non-essential element in the soil that brutally affects plants and other living organisms in soil; hence, its removal has become a worldwide concern. In this work, a multifunctional nanoscale zerovalent-iron assisted biochar (nFe°/BC) was used to minimize the Pb bioavailability in soil with aim of alleviating the Pb-induced toxicity in sunflower. Results revealed that nFe°/BC treatment had significantly improved plant growth (58%), chlorophyll contents (66%), intracellular permeability (60%), and ratio...

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its resulting disease, coronavirus disease 2019 (COVID-19), has spread to millions of people worldwide. Preliminary data from organ transplant recipients have shown reduced seroconversion rates after the administration of different SARS-CoV-2 vaccination platforms. However, it is unknown whether different vaccination platforms provide different levels of protection against SARS-CoV-2. To answer this question, we prospectively studied 431 kidney and liver transplant recipients (kidney: n = 230;...

Additional file 1: Table S1.

Additional file 1: Table S1.

Abstract Background AU-rich elements (AREs) are located in the 3′UTRs of 22% of human mRNAs, including most transiently expressed inflammatory mediators. By default, AREs mark mRNAs for decay and translational inhibition, but this activity can be temporarily inhibited in case of infection to allow the onset of inflammation. Morbidity and mortality in COVID-19 patients have been associated with dysregulated inflammation, a process that may include aberrant ARE activity. Results RNA-seq data from available transcriptomic studies...

Abstract Background The 2021 American College of Rheumatology (ACR) rheumatoid arthritis (RA) guideline considers the specific context of the United States which differs from that of Saudi Arabia in many aspects that may impact recommendations. The objective of this project was to adapt a set of prioritized recommendations from the 2021 ACR guideline for the treatment of rheumatoid arthritis RA for the context of Saudi Arabia, by the Saudi Society for Rheumatology (SSR). Methods The...

Supplemental material, sj-docx-1-pch-10.1177_21501351221139834 for Does Secondary Antibiotic Prophylaxis Improve Clinical Outcomes in Adult Rheumatic Heart Disease Patients Post-Valve Replacement? by Abdulrazaq S Al-Jazairi, Ahlam M Althobaiti, Josef Marek, Edward B Devol, Zohair Al Halees, Dania Mohty and Bahaa M Fadel in World Journal for Pediatric and Congenital Heart Surgery

Supplemental material, sj-pdf-2-pch-10.1177_21501351221139834 for Does Secondary Antibiotic Prophylaxis Improve Clinical Outcomes in Adult Rheumatic Heart Disease Patients Post-Valve Replacement? by Abdulrazaq S Al-Jazairi, Ahlam M Althobaiti, Josef Marek, Edward B Devol, Zohair Al Halees, Dania Mohty and Bahaa M Fadel in World Journal for Pediatric and Congenital Heart Surgery

Lead (Pb) is a biologically non-essential element in the soil that brutally affects plants and other living organisms in soil; hence, its removal has become a worldwide concern. In this work, a multifunctional nanoscale zerovalent-iron assisted biochar (nFe°/BC) was used to minimize the Pb bioavailability in soil with aim of alleviating the Pb-induced toxicity in sunflower. Results revealed that nFe°/BC treatment had significantly improved plant growth (58%), chlorophyll contents (66%), intracellular permeability (60%), and ratio...

A majority of SARS-CoV-2 recoverees develop only mild-to-moderate symptoms, while some remain completely asymptomatic. Although viruses, including SARS-CoV-2, may evade host immune responses by epigenetic mechanisms including DNA methylation, little is known about whether these modifications are important in defence against and healthy recovery from COVID-19 in the host. To this end, epigenome-wide DNA methylation patterns from COVID-19 convalescents were compared to uninfected controls from before and after the pandemic. Peripheral blood mononuclear cell (PBMC)...

Supplementary Table 1: Demographic Parameters of Present Study Cohort Supplementary Table 2: Multivariant Cox regression analysis of selected SNPs Supplementary Table 3: Spearman correlation of selected genes in HNC patients

Abstract Background The 2021 American College of Rheumatology (ACR) rheumatoid arthritis (RA) guideline considers the specific context of the United States which differs from that of Saudi Arabia in many aspects that may impact recommendations. The objective of this project was to adapt a set of prioritized recommendations from the 2021 ACR guideline for the treatment of rheumatoid arthritis RA for the context of Saudi Arabia, by the Saudi Society for Rheumatology (SSR). Methods The...

Additional file 3. Evidence to Decision tables.