32 Works

Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes

Wei Zhang, Rong-Hui Du, Bei Li, Xiao-Shuang Zheng, Xing-Lou Yang, Ben Hu, Yan-Yi Wang, Geng-Fu Xiao, Bing Yan, Zheng-Li Shi & Peng Zhou
In December 2019, a novel coronavirus (2019-nCoV) caused an outbreak in Wuhan, China, and soon spread to other parts of the world. It was believed that 2019-nCoV was transmitted through respiratory tract and then induced pneumonia, thus molecular diagnosis based on oral swabs was used for confirmation of this disease. Likewise, patient will be released upon two times of negative detection from oral swabs. However, many coronaviruses can also be transmitted through oral–fecal route by...

Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes

Wei Zhang, Rong-Hui Du, Bei Li, Xiao-Shuang Zheng, Xing-Lou Yang, Ben Hu, Yan-Yi Wang, Geng-Fu Xiao, Bing Yan, Zheng-Li Shi & Peng Zhou
In December 2019, a novel coronavirus (2019-nCoV) caused an outbreak in Wuhan, China, and soon spread to other parts of the world. It was believed that 2019-nCoV was transmitted through respiratory tract and then induced pneumonia, thus molecular diagnosis based on oral swabs was used for confirmation of this disease. Likewise, patient will be released upon two times of negative detection from oral swabs. However, many coronaviruses can also be transmitted through oral–fecal route by...

Enhancing crop domestication through genomic selection, a case study of intermediate wheatgrass

Jared Crain, Prabin Bajgain, James Anderson, Xiaofei Zhang, Lee DeHaan & Jesse Poland
Perennial grains could simultaneously provide food for humans and a host of ecosystem services, including reduced erosion, minimized nitrate leaching, and increased carbon capture. Yet most of the world’s food and feed is supplied by annual grains. Efforts to domesticate intermediate wheatgrass (Thinopyrumn intermedium, IWG) as a perennial grain crop have been ongoing since the 1980’s. Currently, there are several breeding programs within North America and Europe working toward developing IWG into a viable crop....

Shape matters: The relationship between cell geometry and diversity in phytoplankton

Alexey Ryabov, Onur Kerimoglu, Irina Olenina, Leonilde Roselli, Alberto Basset, Elena Stanca, Elena Litchman & Bernd Blasius
We compiled the most comprehensive data set of phytoplankton and other marine protists in terms of sizes, shapes, genus, and species names. Samples were obtained from seven globally distributed marine areas: Baltic Sea, North Atlantic (Scotland), Mediterranean Sea (Greece and Turkey), Indo-Pacific (the Maldives), South-western Pacific (Australia), Southern Atlantic (Brazil). See details in Ryabov et al Ecology Letters 'Shape matters: the relationship between cell geometry and diversity in phytoplankton', https://doi.org/10.1111/ele.13680

Genomic prediction enables rapid selection of high-performing genets in an intermediate wheatgrass (Thinopyrum intermedium) breeding program

Jared Crain, Lee DeHaan & Jesse Poland
In an era of constrained and depleted natural resources, perennial grains could provide sustainable food production in addition to beneficial ecosystem services like reduced erosion and increased atmospheric carbon capture. One such perennial, intermediate wheatgrass (IWG; Thinopyrum intermedium) has been undergoing continuous breeding for domestication and improvement to develop a perennial grain crop since the 1980’s. However, as a perennial species, IWG has required 2-5 years per selection generation. Therefore, starting in 2017 genomic selection...

Data from: Adaptive genetic potential and plasticity of trait variation in the foundation prairie grass Andropogon gerardii across the US Great Plains’ climate gradient: Implications for climate change and restoration

Loretta C. Johnson, Matthew Galliart, Sofia Sabates, Hannah Tetreault, Angel DeLaCruz, Johnny Bryant, Jacob Alsdurf, Mary Knapp, Nora Bello, Sara Baer, Brian Maricle, David Gibson, Jesse Poland, Paul St. Amand, Natalie Unruh, Olivia Parrish & Loretta Johnson
Plant response to climate depends on a species’ adaptive potential. To address this, we used reciprocal gardens to detect genetic and environmental plasticity effects on phenotypic variation and combined with genetic analyses. Four reciprocal garden sites were planted with three regional ecotypes of Andropogon gerardii, a dominant Great Plains prairie grass, using dry, mesic, wet ecotypes originating from western KS to Illinois that span 500 to 1,200 mm rainfall year-1. We aimed to answer: (1)...

Frequent burning causes large losses of carbon from deep soil layers in a temperate savanna

Adam Francis Pellegrini, Kendra K. McLauchlan, Sarah E. Hobbie, Michelle C. Mack, Abbey L. Marcotte, David M. Nelson, Steven Perakis, Peter B. Reich & Kyle Whittinghill
1. Fire activity is changing dramatically across the globe, with uncertain effects on ecosystem processes, especially belowground. Fire‐driven losses of soil carbon (C) are often assumed to occur primarily in the upper soil layers because the repeated combustion of aboveground biomass limits organic matter inputs into surface soil. However, C losses from deeper soil may occur if frequent burning reduces root biomass inputs of C into deep soil layers or stimulates losses of C via...

Prolonged shedding of severe acute respiratory syndrome coronavirus 2 in patients with COVID-19

Qian Li, Xiao-Shuang Zheng, Xu-Rui Shen, Hao-Rui Si, Xi Wang, Qi Wang, Bei Li, Wei Zhang, Yan Zhu, Ren-Di Jiang, Kai Zhao, Hui Wang, Zheng-Li Shi, Hui-Lan Zhang, Rong-Hui Du & Peng Zhou
Following acute infection, individuals COVID-19 may still shed SARS-CoV-2 RNA. However, limited information is available regarding the active shedding period or whether infectious virus is also shed. Here, we monitored the clinical characteristics and virological features of 38 patients with COVID-19 (long-term carriers) who recovered from the acute disease, but still shed viral RNA for over 3 months. The median carrying history of the long-term carriers was 92 days after the first admission, and the...

Prolonged shedding of severe acute respiratory syndrome coronavirus 2 in patients with COVID-19

Qian Li, Xiao-Shuang Zheng, Xu-Rui Shen, Hao-Rui Si, Xi Wang, Qi Wang, Bei Li, Wei Zhang, Yan Zhu, Ren-Di Jiang, Kai Zhao, Hui Wang, Zheng-Li Shi, Hui-Lan Zhang, Rong-Hui Du & Peng Zhou
Following acute infection, individuals COVID-19 may still shed SARS-CoV-2 RNA. However, limited information is available regarding the active shedding period or whether infectious virus is also shed. Here, we monitored the clinical characteristics and virological features of 38 patients with COVID-19 (long-term carriers) who recovered from the acute disease, but still shed viral RNA for over 3 months. The median carrying history of the long-term carriers was 92 days after the first admission, and the...

Tranilast attenuates neuropathic pain during type-2 diabetes by inhibiting hypoxia-induced pro-inflammatory cytokines in Zucker diabetic fatty rat model

Wei Zhang, Jun Ma, Shan Wang, Tao Huang & Min Xia
The modulatory effect of tranilast on neuropathic pain in type-2 diabetes (T2DM) remains unclear. We monitored interleukin (IL)-1β, nuclear factor-κB (NF-κB) and tumour necrosis factor-α (TNF-α) levels during the progression of T2DM induced neuropathic pain in rats, and assessed the impact of tranilast treatment of increasing concentrations (0, 200 and 400 mg/kg/day via oral gavage in 1% NaHCO3 delivered as 100 mg/kg twice a day) on the levels of cytokine production, as well as on...

Functional consequences of phenotypic variation between locally adapted populations: swimming performance and ventilation in extremophile fish

Michael Tobler, Lenin Arias-Rodriguez & Henry Camarillo
Natural selection drives the evolution of traits to optimize organismal performance, but optimization of one aspect of performance can often influence other aspects of performance. Here, we asked how phenotypic variation between locally adapted fish populations affects locomotion and ventilation, testing for functional trade-offs and trait-performance correlations. Specifically, we investigated two populations of livebearing fish (Poecilia mexicana) that inhabit distinct habitat types (hydrogen-sulfide-rich springs and adjacent nonsulfidic streams). For each individual, we quantified different metrics...

Trends in prevalence and incidence of scabies from 1990 to 2017: findings from the global Burden of disease study 2017

Wei Zhang, Yujiao Zhang, Lina Luo, Wenyong Huang, Xiaoping Shen, Xian Dong, Wen Zeng & Hongguang Lu
Scabies remains a significant public health concern globally, affecting people of all ages, races, and socioeconomic groups. The epidemic characteristics of scabies are yet unravelled, especially in high-income countries and elderly population. In this study, we sought to investigate incidence and prevalence and their trends of scabies worldwide from 1990 to 2017 via the Global Burden of Disease (GBD) Study 2017. The prevalence and incidence of scabies tend to a moderate increase after age 70....

The sunflower (Helianthus annuusL.) genome reflects a recent history of biased accumulation of transposable elements

S. Evan Staton, Bradley H. Bakken, Benjamin K. Blackman, Mark A. Chapman, Nolan C. Kane, Shunxue Tang, Mark C. Ungerer, Steven J. Knapp, Loren H. Rieseberg & John M. Burke
Aside from polyploidy, transposable elements are the major drivers of genome size increases in plants. Thus, understanding the diversity and evolutionary dynamics of transposable elements in sunflower (Helianthus annuus L.), especially given its large genome size (∼3.5 Gb) and the well‐documented cases of amplification of certain transposons within the genus, is of considerable importance for understanding the evolutionary history of this emerging model species. By analyzing approximately 25% of the sunflower genome from random sequence...

Susceptibility of swine cells and domestic pigs to SARS-CoV-2

David A. Meekins, Igor Morozov, Jessie D. Trujillo, Natasha N. Gaudreault, Dashzeveg Bold, Mariano Carossino, Bianca L. Artiaga, Sabarish V. Indran, Taeyong Kwon, Velmurugan Balaraman, Daniel W. Madden, Heinz Feldmann, Jamie Henningson, Wenjun Ma, Udeni B. R. Balasuriya & Juergen A. Richt
The emergence of SARS-CoV-2 has resulted in an ongoing global pandemic with significant morbidity, mortality, and economic consequences. The susceptibility of different animal species to SARS-CoV-2 is of concern due to the potential for interspecies transmission, and the requirement for pre-clinical animal models to develop effective countermeasures. In the current study, we determined the ability of SARS-CoV-2 to (i) replicate in porcine cell lines, (ii) establish infection in domestic pigs via experimental oral/intranasal/intratracheal inoculation, and...

Data on universities offering undergraduate degrees that train students for soil science careers at universities in the USA and its territories

Eric C. Brevik, Holly Dolliver, Susan Edinger-Marshall, Danny Itkin, Jodi Johnson-Maynard, Garrett Liles, Monday Mbila, Colby Moorberg, Yaniria Sanchez-De Leon, Joshua J. Steffan, April Ulery & Karen Vaughan
Several soil science education studies over the last 15 years have focused on the number of students enrolled in soil science programs. However, no studies have quantitatively addressed the number of undergraduate soil science preparatory programs that exist in the United States, which means we do not have solid data concerning whether overall program numbers are declining, rising, or holding steady. This also means we do not have complete data on the same trends for...

Retracted article: Tranilast attenuates neuropathic pain during type-2 diabetes by inhibiting hypoxia-induced pro-inflammatory cytokines in Zucker diabetic fatty rat model

Wei Zhang, Jun Ma, Shan Wang, Tao Huang & Min Xia
We, the Editors and Publisher of the journalArchives of Physiology and Biochemistry, have retracted the following article: Wei Zhang, Jun Ma, Shan Wang, Tao Huang & Min Xia (2020) Tranilast attenuates neuropathic pain during type-2 diabetes by inhibiting hypoxia-induced pro-inflammatory cytokines in Zucker diabetic fatty rat model, Archives of Physiology and Biochemistry, DOI: 10.1080/13813455.2020.1854309 Since publication, the authors informed the Publisher and Editor that the authors had not received ethics approval from the Institutional Animal...

Assembly of Aegilops comosa chromosomes

Mahmoud Said, Kateřina Holušová, András Farkas, László Ivanizs, Eszter Gaál, Petr Cápal, Michael Abrouk, Mihaela Martis-Thiele, Balázs Kalapos, Jan Bartoš, Bernd Friebe, Jaroslav Doležel & István Molnár
We sequenced and assembled seven chromosomes of Aegilops comosa. The assembly with Meraculous resulted in ~ 50k - 186k scaffolds per chromosome with N50 size 6.4kb - 20.2kb. The scaffold sequences were used for development of molecular markers specific for cDNAs sequences mapped on Ae. comosa chromosomes Pairwise alignment of wheat cDNA-sequences and the chromosomal scaffolds of Ae. comosa identified candidate sequences. In order to analyze the structure and homeology of Aegilops chromosomes, forty-three mapped...

Acylation of the antimicrobial peptide CAMEL for cancer gene therapy

Jingjing Song, Panpan Ma, Sujie Huang, Juanli Wang, Huan Xie, Bo Jia & Wei Zhang
Obtaining ideal gene delivery vectors is still a major goal in cancer gene therapy. CAMEL, a short hybrid antimicrobial peptide, can kill cancer cells by membrane lysis. In this study, we constructed a series of non-viral vectors by attaching fatty acids with different chain lengths to the N-terminus of CAMEL. Our results showed that the cellular uptake and transfection efficiency of acyl-CAMEL started to significantly increase from a chain length of 12 carbons. C18-CAMEL was...

Pathogen genetic control of transcriptome variation in the Arabidopsis thaliana – Botrytis cinerea pathosystem

Nicole Soltis, Celine Caseys, Wei Zhang, Jason Corwin, Susanna Atwell & Daniel Kliebenstein
In plant-pathogen relations, disease symptoms arise from the interaction of the host and pathogen genomes. Host-pathogen functional gene interactions are well described while little is known about how the pathogen genetic variation modulates both organisms’ transcriptomes. To model and generate hypotheses on a generalist pathogen control of gene expression regulation, we used the Botrytis cinerea - Arabidopsis thaliana pathosystem and the genetic diversity of a collection of 96 B. cinerea isolates. We performed expression-based genome-wide...

Bridging the flux gap: sap flow measurements reveal species-specific patterns of water-use in a tallgrass prairie

Kimberly O'Keefe, David Bell, Katherine McCulloh & Jesse Nippert
Predicting the hydrological consequences following changes in grassland vegetation type (i.e., woody encroachment) requires an understanding of water flux dynamics at high spatiotemporal resolution for predominant species within grassland communities. However, grassland fluxes are typically measured at the leaf or landscape scale, which inhibits our ability to predict how individual species contribute to changing ecosystem fluxes. We used external heat balance sap flow sensors and a hierarchical Bayesian state-space modeling approach to bridge this “flux-gap”...

Trends in prevalence and incidence of scabies from 1990 to 2017: findings from the global Burden of disease study 2017

Wei Zhang, Yujiao Zhang, Lina Luo, Wenyong Huang, Xiaoping Shen, Xian Dong, Wen Zeng & Hongguang Lu
Scabies remains a significant public health concern globally, affecting people of all ages, races, and socioeconomic groups. The epidemic characteristics of scabies are yet unravelled, especially in high-income countries and elderly population. In this study, we sought to investigate incidence and prevalence and their trends of scabies worldwide from 1990 to 2017 via the Global Burden of Disease (GBD) Study 2017. The prevalence and incidence of scabies tend to a moderate increase after age 70....

Trends in Prevalence and Incidence of Scabies from 1990 to 2017: Findings from the Global Burden of Disease Study 2017

Wei Zhang, Yujiao Zhang, Lina Luo, Wenyong Huang, Xiaoping Shen, Xian Dong, Wen Zeng & Hongguang Lu
Scabies remains a significant public health concern globally, affecting people of all ages, races, and socioeconomic groups. The epidemic characteristics of scabies are yet unraveled, especially in high-income countries and elderly population. In this study, we sought to investigate incidence and prevalence and their trends of scabies worldwide from 1990 to 2017 via the Global Burden of Disease (GBD) Study 2017. The prevalence and incidence of age-standardized rate (ASR) of scabies tend to a moderate...

Sequenced-based paternity analysis to improve breeding and identify self-incompatibility loci in intermediate wheatgrass (Thinopyrum intermedium)

Jared Crain, Steve Larson, Kevin Dorn, Traci Hagedorn, Lee DeHaan & Jesse Poland
In outcrossing species such as intermediate wheatgrass (IWG, Thinopyrum intermedium), polycrossing is often used to generate novel recombinants through each cycle of selection, but it cannot track pollen-parent pedigrees and it is unknown how self-incompatibility (SI) genes may limit the number of unique crosses obtained. This study investigated the potential of using next-generation sequencing to assign paternity and identify putative SI loci in IWG. Using a reference population of 380 individuals made from controlled crosses...

Susceptibility of swine cells and domestic pigs to SARS-CoV-2

David A. Meekins, Igor Morozov, Jessie D. Trujillo, Natasha N. Gaudreault, Dashzeveg Bold, Mariano Carossino, Bianca L. Artiaga, Sabarish V. Indran, Taeyong Kwon, Velmurugan Balaraman, Daniel W. Madden, Heinz Feldmann, Jamie Henningson, Wenjun Ma, Udeni B. R. Balasuriya & Juergen A. Richt
The emergence of SARS-CoV-2 has resulted in an ongoing global pandemic with significant morbidity, mortality, and economic consequences. The susceptibility of different animal species to SARS-CoV-2 is of concern due to the potential for interspecies transmission, and the requirement for pre-clinical animal models to develop effective countermeasures. In the current study, we determined the ability of SARS-CoV-2 to (i) replicate in porcine cell lines, (ii) establish infection in domestic pigs via experimental oral/intranasal/intratracheal inoculation, and...

A genomics resource for genetics, physiology, and breeding of West African sorghum

Jacques Faye, Fanna Maina, Eyanawa Akata, Bassirou Sine, Cyril Diatta, Aissata Mamadou, Sandeep Marla, Sophie Bouchet, Niaba Teme, Jean-Francois Rami, Daniel Fonceka, Ndiaga Cisse & Geoffrey Morris
Local landrace and breeding germplasm is a useful source of genetic diversity for regional and global crop improvement initiatives. Sorghum (Sorghum bicolor L. Moench) in West Africa has diversified across a mosaic of cultures and end-uses, and along steep precipitation and photoperiod gradients. To facilitate germplasm utilization, a West African sorghum association panel (WASAP) of 756 accessions from national breeding programs of Niger, Mali, Senegal, and Togo was assembled and characterized. Genotyping-by-sequencing was used to...

Registration Year

  • 2020
    32

Resource Types

  • Dataset
    21
  • Text
    11

Affiliations

  • Kansas State University
    32
  • Northwestern University
    11
  • Jiangsu Academy of Agricultural Sciences
    11
  • Beijing Tian Tan Hospital
    11
  • Third Hospital of Hebei Medical University
    11
  • North West Agriculture and Forestry University
    11
  • Sun Yat-sen University
    11
  • West China Hospital of Sichuan University
    11
  • Agricultural University of Hebei
    11
  • Zhejiang University
    11