17 Works

Unexpected morphological diversity in ancient dogs compared to modern relatives

Colline Brassard, Adrian Bălășescu, Rose-Marie Arbogast, Vianney Forest, Céline Bemilli, Adina Boroneant, Fabien Convertini, Muriel Gandelin, Valentin Radu, Patricia Fleming, Claude Guintard, Tracey Kreplins, Cécile Callou, Andréa Filippo, Anne Tresset, Raphaël Cornette, Anthony Herrel & Stéphanie BREHARD
Dogs are among the most variable species today, but little is known about the morphological variability in the early phases of their history. The Neolithic transition to farming may have resulted in an early morphological diversification as a result of changes in the anthropic environment or intentional selection on specific morphologies. Here, we explore the variability and modularity in mandible form by comparing 525 dog mandibles from European archaeological sites ranging from 8,100 to 3,000...

Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Abstract Background The palate is a structure separating the oral and nasal cavities and its integrity is essential for feeding and breathing. The total or partial opening of the palate is called a cleft palate and is a common malformation in mammals with environmental or hereditary aetiologies. Generally, it compromises life expectancy in the absence of surgical repair. A new form of non-syndromic cleft palate arose recently in Limousine cattle, with animals referred to the...

Modelling the effects of antimicrobial metaphylaxis and pen size on bovine respiratory disease in high and low risk fattening cattle

Sébastien Picault, Pauline Ezanno, Kristen Smith, David Amrine, Brad White & Sébastien Assié
Abstract Bovine respiratory disease (BRD) dramatically affects young calves, especially in fattening facilities, and is difficult to understand, anticipate and control due to the multiplicity of factors involved in the onset and impact of this disease. In this study we aimed to compare the impact of farming practices on BRD severity and on antimicrobial usage. We designed a stochastic individual-based mechanistic BRD model which incorporates not only the infectious process, but also clinical signs, detection...

Additional file 3 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 3: Figure S1. Results of the homozygosity mapping on all the bovine chromosomes. LRT: likelihood-ratio test; BTA: Bos taurus chromosome.

Additional file 1 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 1: Table S1. List of the disorders in animals (except man, mouse, rat and zebrafish) which include “cleft palate” as a clinical sign. All the data originate from OMIA (Online Mendelian Inheritance in Animals, www.omia.org ). All the cattle disorders are written in bold. AR: autosomal recessive; AD: autosomal dominant; UK: unknown.

Additional file 1 of Modelling the effects of antimicrobial metaphylaxis and pen size on bovine respiratory disease in high and low risk fattening cattle

Sébastien Picault, Pauline Ezanno, Kristen Smith, David Amrine, Brad White & Sébastien Assié
Additional file 1. Additional information on the processes involved in the model (section 1) and the whole content of the model (section 2).

Additional file 2 of Modelling the effects of antimicrobial metaphylaxis and pen size on bovine respiratory disease in high and low risk fattening cattle

Sébastien Picault, Pauline Ezanno, Kristen Smith, David Amrine, Brad White & Sébastien Assié
Additional file 2. BRD model in EMULSION format. BRD model expressed within the modelling language used by the EMULSION simulation engine (based on YAML format).

Modelling the effects of antimicrobial metaphylaxis and pen size on bovine respiratory disease in high and low risk fattening cattle

Sébastien Picault, Pauline Ezanno, Kristen Smith, David Amrine, Brad White & Sébastien Assié
Abstract Bovine respiratory disease (BRD) dramatically affects young calves, especially in fattening facilities, and is difficult to understand, anticipate and control due to the multiplicity of factors involved in the onset and impact of this disease. In this study we aimed to compare the impact of farming practices on BRD severity and on antimicrobial usage. We designed a stochastic individual-based mechanistic BRD model which incorporates not only the infectious process, but also clinical signs, detection...

Additional file 1 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 1: Table S1. List of the disorders in animals (except man, mouse, rat and zebrafish) which include “cleft palate” as a clinical sign. All the data originate from OMIA (Online Mendelian Inheritance in Animals, www.omia.org ). All the cattle disorders are written in bold. AR: autosomal recessive; AD: autosomal dominant; UK: unknown.

Additional file 3 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 3: Figure S1. Results of the homozygosity mapping on all the bovine chromosomes. LRT: likelihood-ratio test; BTA: Bos taurus chromosome.

Additional file 1 of Modelling the effects of antimicrobial metaphylaxis and pen size on bovine respiratory disease in high and low risk fattening cattle

Sébastien Picault, Pauline Ezanno, Kristen Smith, David Amrine, Brad White & Sébastien Assié
Additional file 1. Additional information on the processes involved in the model (section 1) and the whole content of the model (section 2).

Additional file 2 of Modelling the effects of antimicrobial metaphylaxis and pen size on bovine respiratory disease in high and low risk fattening cattle

Sébastien Picault, Pauline Ezanno, Kristen Smith, David Amrine, Brad White & Sébastien Assié
Additional file 2. BRD model in EMULSION format. BRD model expressed within the modelling language used by the EMULSION simulation engine (based on YAML format).

Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Abstract Background The palate is a structure separating the oral and nasal cavities and its integrity is essential for feeding and breathing. The total or partial opening of the palate is called a cleft palate and is a common malformation in mammals with environmental or hereditary aetiologies. Generally, it compromises life expectancy in the absence of surgical repair. A new form of non-syndromic cleft palate arose recently in Limousine cattle, with animals referred to the...

Additional file 4 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 4: Table S3. Frequency analysis of the MYH3 mutations in 834,792 animals from 14 commercial breeds based on genotyping with EuroG10k v8 and EuroGMD SNP chips. The two mutations are totally linked, thus the frequency is the same for both mutations. freq_WTall: frequency of the WT allele; freq_MUTall: frequency of the mutated allele.

Additional file 4 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 4: Table S3. Frequency analysis of the MYH3 mutations in 834,792 animals from 14 commercial breeds based on genotyping with EuroG10k v8 and EuroGMD SNP chips. The two mutations are totally linked, thus the frequency is the same for both mutations. freq_WTall: frequency of the WT allele; freq_MUTall: frequency of the mutated allele.

Additional file 2 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 2: Table S2. Characteristics of the 26 Limousine CP-affected animals described in this study.

Additional file 2 of Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle

Anne Vaiman, Sébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte & Amandine Duchesne
Additional file 2: Table S2. Characteristics of the 26 Limousine CP-affected animals described in this study.

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