Additional file 3. Heatwave characteristics for period 2020 – 2039 using data simulated from RCP 4.5 projections.

Additional file 1. Detailed study methodology.

Abstract Background Adolescents who have acquired HIV perinatally (ALHIV) face unique challenges in taking lifelong antiretroviral therapy (ART), but little is known about what factors affect their adherence over the course of their lifelong treatment journey. Methods We conducted a qualitative study with ALHIV who had periods of poor adherence to ART in KwaZulu-Natal, South Africa using Participant-generated Visual Methodologies (PVM). Participants used photography to represent their perspectives and experiences. Results 14 individuals participated in...

Additional file 2. Additional tables.

Additional file 1. Table S1. Search strategy in MEDLINE. Table S2. Critical appraisal results of included quasi-experimental studies (quantitative studies). Table S3. Critical appraisal results of included randomized controlled trial (quantitative study). Table S4. Critical appraisal results of included qualitative studies and mixed methods study (qualitative component).

Abstract Background Good health decisions depend on one’s ability to think critically about health claims and make informed health choices. Young people can learn these skills through school-based interventions, but learning resources need to be low-cost and built around lessons that can fit into existing curricula. As a first step to developing and evaluating digital learning resources that are feasible to use in Kenyan secondary schools, we conducted a context analysis to explore interest in...

Additional file 3: Supplementary Table S3. Comparison between the Gibbs Framework and the GRIPP-2(SF).

Additional file 1.

Additional file 1.

Additional file 1: Appendix 1. Search strategy.

Additional file 1.

Abstract Background Air pollution is a global, public health emergency. The effect of living in areas with very poor air quality on adolescents’ physical health is largely unknown. The aim of this study was to investigate the prevalence of adverse respiratory health outcomes among adolescents living in a known air pollution hotspot in South Africa. Methods Ambient air quality data from 2005 to 2019 for the two areas, Secunda and eMbalenhle, in the Highveld Air...

Additional file 1.

Abstract Background PrEP literacy is influenced by many factors including the types of information available and how it is interpreted. The level of PrEP literacy may influence acceptability and uptake. Methods We conducted 25 in-depth interviews in a HIV vaccine trial preparedness cohort study. We explored what participants knew about PrEP, sources of PrEP knowledge and how much they know about PrEP. We used the framework approach to generate themes for analysis guided by the...

Additional file 2. Heatwave characteristics from 2014 - 2019 as defined using threshold of 12.8 oC and duration of two days or more.

Additional file 2. Heatwave characteristics from 2014 - 2019 as defined using threshold of 12.8 oC and duration of two days or more.

Additional file 2: Supplementary Table S2. Results of application of Gibbs Framework and GRIPP-2(SF) to publications from Project MIND.

Additional file 2: Supplementary Table S2. Results of application of Gibbs Framework and GRIPP-2(SF) to publications from Project MIND.

Additional file 3: Supplementary Table S3. Comparison between the Gibbs Framework and the GRIPP-2(SF).

Additional file 5. COREQ checklist.

Additional file 4. Heatwave characteristics for period 2020 – 2039 using data simulated from RCP 8.5 projections.

Abstract Background Adolescents who have acquired HIV perinatally (ALHIV) face unique challenges in taking lifelong antiretroviral therapy (ART), but little is known about what factors affect their adherence over the course of their lifelong treatment journey. Methods We conducted a qualitative study with ALHIV who had periods of poor adherence to ART in KwaZulu-Natal, South Africa using Participant-generated Visual Methodologies (PVM). Participants used photography to represent their perspectives and experiences. Results 14 individuals participated in...

Abstract Background Interventions aimed at reducing risky sexual behavior are considered an important strategy for averting Human Immunodeficiency Virus (HIV) infection among youth (15–24 years) who continue to be at risk of the disease. Enhancing intervention success requires a comprehensive understanding of the barriers and facilitators to interventions targeting youth. However, there is lack of a systematic review of both quantitative and qualitative studies to comprehensively identify and synthesize barriers and facilitators to HIV prevention...

Abstract Background Interventions aimed at reducing risky sexual behavior are considered an important strategy for averting Human Immunodeficiency Virus (HIV) infection among youth (15–24 years) who continue to be at risk of the disease. Enhancing intervention success requires a comprehensive understanding of the barriers and facilitators to interventions targeting youth. However, there is lack of a systematic review of both quantitative and qualitative studies to comprehensively identify and synthesize barriers and facilitators to HIV prevention...

Background: Rape is a common traumatic event which may result in the development of posttraumatic stress disorder (PTSD), yet few studies have investigated risk biomarkers in sexually traumatised individuals. Adiponectin is a novel cytokine within inflammatory and cardiometabolic pathways with evidence of involvement in PTSD. Objective: This prospective exploratory study in a sample of female rape survivors investigated the association of single nucleotide polymorphisms (SNPs) in the adiponectin gene (ADIPOQ) and posttraumatic stress symptom (PTSS)...