Supplemental Material for Patient and stakeholder perspectives on impacts of the COVID-19 pandemic on HIV and mental health care delivery in South Africa by Alexandra L Rose, Yvonne A Ochieng, Helen E Jack, Anu Sangraula, Nonceba Ciya, Yuche Jacobs, Sibabalwe Ndamase, Kristen S Regenauer, Imani Brown, Abigail C Hines, Kim Johnson, Ingrid V Bassett, John A Joska, Jessica F Magidson and Bronwyn Myers in International Journal of STD & AIDS

When profiling blood samples by RNA-sequencing (RNA-seq), RNA from haemoglobin (Hgb) can account for up to 70% of the transcriptome. Due to considerations of sequencing depth and power to detect biological variation, Hgb RNA is typically depleted prior to sequencing by hybridisation-based methods; an alternative approach is to deplete reads arising from Hgb RNA bioinformatically. In the present study, we compared the impact of these two approaches on the outcome of differential gene expression analysis...

Abstract Background Tuberculosis (TB)-associated mortality in South Africa remains high. This review aimed to systematically assess risk factors associated with death during TB treatment in South African patients. Methods We conducted a systematic review of TB research articles published between 2010 and 2018. We searched BioMed Central (BMC), PubMed®, EBSCOhost, Cochrane, and SCOPUS for publications between January 2010 and December 2018. Searches were conducted between August 2019 and October 2019. We included randomised control trials...

Additional file 4: Supplementary Material 4. Interview Consent Form Sample.

Abstract Introduction The COVID-19 pandemic underlined that guidelines and recommendations must be made more accessible and more understandable to the general public to improve health outcomes. The objective of this study is to evaluate, quantify, and compare the public’s understanding, usability, satisfaction, intention to implement, and preference for different ways of presenting COVID-19 health recommendations derived from the COVID-19 Living Map of Recommendations and Gateway to Contextualization (RecMap). Methods and analysis This is a protocol...

Additional file 2: A: Medline search strategy used for the Cochrane (parent) review on Health care worker perceptions and experiences of PHC integration [15]

Abstract Background Integrated delivery of primary health care (PHC) services is a health reform recommended for achieving ambitious targets of the Sustainable Development Goals and Universal Health Coverage, responding to growing challenges of managing non-communicable and multimorbidity. However, more evidence is needed on effective implementation of PHC integration in different country settings. Objective This rapid review synthesized qualitative evidence on implementation factors affecting integration of non-communicable disease (NCD) into PHC, from the perspective of implementers....

Additional file 4: Supplemental results.1. README. 2. Prevalence range across districts. 3. Prevalence range between sexes. 4. Prevalence range between ages. 5. Age-specific district ranges.

Abstract Background Diabetes and hypertension are increasingly important population health challenges in Eswatini. Prior to this project, healthcare for these conditions was primarily provided through physician-led teams at tertiary care facilities and accessed by only a small fraction of people living with diabetes or hypertension. This trial tests and evaluates two community-based healthcare service models implemented at the national level, which involve health care personnel at primary care facilities and utilize the country’s public sector...

Abstract Background Diabetes and hypertension are increasingly important population health challenges in Eswatini. Prior to this project, healthcare for these conditions was primarily provided through physician-led teams at tertiary care facilities and accessed by only a small fraction of people living with diabetes or hypertension. This trial tests and evaluates two community-based healthcare service models implemented at the national level, which involve health care personnel at primary care facilities and utilize the country’s public sector...

Abstract Background Voices of under-resourced communities are recognised as important yet are often unheard in decisions about healthcare resource allocation. Deliberative public engagement can serve as an effective mechanism for involving communities in establishing nutrition priorities. This study sought to identify the priorities of community members of a South African township, Soweto, and describe the underlying values driving their prioritisation process, to improve nutrition in the first 1000 days of life. Methods We engaged 54...

Additional file 3. Resources for IINDIAGO intervention.

Additional file 2. IINDIAGO matrix: Expanded COM-B: TDF domains, theoretical constructs and relevance to GDM women (identified barriers & enablers): Self-care.

Background: Understanding stakeholders’ (parents’, communities’ and health workers’) perspectives of communication about childhood vaccination, including their preferences for its format, delivery and content, is an important step towards designing better communication strategies and ensuring more informed parents. Our objectives were to explore stakeholders’ views, experiences and preferences for childhood vaccination communication in Cameroon. Methods: In 2014, in the Central and North West Regions of Cameron, we gathered qualitative data for our case study using the...

Additional file 1: Supplementary Material 1. SPIRIT Checklist.

Additional file 3: Supplementary Material 3. Survey Consent Form Sample.

Additional file 4: Supplementary Material 4. Interview Consent Form Sample.

Additional file 1: Box 1. Anthropometry data cleaning criteria. Figure S1. Directed Acyclic Graph representing the hypothesized relationships, 2012–2014, South Africa. Figure S2. Study cohort profile of HIV exposed uninfected infants from 6-weeks to 18-months postpartum, 2012–2014, South Africa. Table S1. Proportion of underweight children from 6-weeks to 18-months postpartum by in-utero antiretroviral exposure status, 2012–2014, South Africa. Table S2. Proportion of stunted children from 6-weeks to 18-months postpartum by in-utero antiretroviral exposure status, 2012–2014,...

Additional file 2: A: Medline search strategy used for the Cochrane (parent) review on Health care worker perceptions and experiences of PHC integration [15]

Additional file 5: Table:CERQual assessments for seven main findings of the PHC Integration rapid review.

Abstract Background Clinical trial participants have a right to be informed throughout the entire process of human subject research. As part of this pillar of research ethics, participants and other stakeholders should be made aware of research findings after a trial has been completed. Though participants have both a right, and a desire to be informed of research outcomes, studies show that they rarely receive communication about study findings. Our aim was (1) to understand...

Additional file 1: Supplementary material. Description of data: Complete list of outcomes and variables for which data were sought; PRISMA 2020 checklist. Supplementary Table 1. Newcastle-Ottawa quality assessment scale for cohort studies, South Africa, 2010-2018 (n=21). Supplementary Table 2. Cochrane risk of bias tool for randomised trials, South Africa, 2010-2018 (n=2). Supplementary Table 3. Newcastle-Ottawa quality assessment scale for case control studies, South Africa, 2010-2018 (n=1). Supplementary Table 4. Demographic risk factors for TB mortality....

Abstract Background Disruptions in essential health services during the COVID-19 pandemic have been reported in several countries. Yet, patterns in health service disruption according to country responses remain unclear. In this paper, we investigate associations between the stringency of COVID-19 containment policies and disruptions in 31 health services in 10 low- middle- and high-income countries in 2020. Methods Using routine health information systems and administrative data from 10 countries (Chile, Ethiopia, Ghana, Haiti, Lao People’s...

Additional file 1.

Additional file 1: Supplementary File 1. List of Included Studies.