8 Works

Data from: Genetic background and GxE interactions modulate the penetrance of a naturally occurring wing mutation in Drosophila melanogaster

Joseph Lachance, Lawrence Jung & John R. True
Many genes involved in producing complex traits are incompletely penetrant. One such example is vesiculated, an X-linked gene in Drosophila melanogaster that results in wing defects. To examine the genetic architecture of a complex trait (wings containing vesicles), we placed a naturally occurring variant into multiple autosomal backgrounds and quantified penetrance and expressivity at a range of developmental temperatures. We found significant epistasis, genotype-by-environment interactions, and maternal effects. Sex and temperature effects were modulated by...

Data from: How climate extremes—not means—define a species' geographic range boundary via a demographic tipping point

Heather J. Lynch, Marc Rhainds, Justin M. Calabrese, Stephen Cantrell, Chris Cosner & William F. Fagan
Species’ geographic range limits interest biologists and resource managers alike; however, scientists lack strong mechanistic understanding of the factors that set geographic range limits in the field, especially for animals. There exists a clear need for detailed case studies that link mechanisms to spatial dynamics and boundaries because such mechanisms allow us to predict whether climate change is likely to change a species’ geographic range and, if so, how abundance in marginal populations compares to...

Data from: Ecological causes of decelerating diversification in carnivoran mammals

Antonin Machac, David Storch & John J. Wiens
Clade diversification is a central topic in macroevolutionary studies. Recently, it has been shown that diversification rates appear to decelerate over time in many clades. What causes this deceleration remains unclear, but it has been proposed that competition for limited resources between sympatric, ecologically similar species slows diversification. Employing carnivoran mammals as a model system, we test this hypothesis using a comprehensive time-calibrated phylogeny. We also explore several conceptually related explanations including limited geographic area...

Data from: Assessment of coyote-wolf-dog admixture using ancestry-informative diagnostic SNPs

Javier Monzón, Roland Kays & Daniel E. Dykhuizen
The evolutionary importance of hybridization as a source of new adaptive genetic variation is rapidly gaining recognition. Hybridization between coyotes and wolves may have introduced adaptive alleles into the coyote gene pool that facilitated an expansion in their geographic range and dietary niche. Furthermore, hybridization between coyotes and domestic dogs may facilitate adaptation to human-dominated environments. We genotyped 63 ancestry-informative single nucleotide polymorphisms in 427 canids in order to examine the prevalence, spatial distribution, and...

Data from: Fossil grebes from the Truckee Formation (Miocene) of Nevada and a new phylogenetic analysis of Podicipediformes (Aves)

Daniel T. Ksepka, Amy M. Balanoff, Michael A. Bell & Michel D. Houseman
Podicipediformes is a cosmopolitan clade of foot-propelled diving birds that, despite inhabiting marine and lacustrine environments, have a poor fossil record. In this contribution, we describe three new grebe fossils from the diatomite beds of the Late Miocene Truckee Formation (10.2 ± 0.2 Ma) of Nevada (USA). Two postcranial skeletons and an associated set of wing elements indicate that at least two distinct grebe species occupied the large, shallow Lake Truckee during the Miocene. Phylogenetic...

Data from: Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double-strand breaks

Yan Liu, William A. Gaines, Tracy Callender, Valeria Busygina, Ashwini Oke, Patrick Sung, Jennifer C. Fung & Nancy M. Hollingsworth
Interhomolog recombination plays a critical role in promoting proper meiotic chromosome segregation but a mechanistic understanding of this process is far from complete. In vegetative cells, Rad51 is a highly conserved recombinase that exhibits a preference for repairing double strand breaks (DSBs) using sister chromatids, in contrast to the conserved, meiosis-specific recombinase, Dmc1, which preferentially repairs programmed DSBs using homologs. Despite the different preferences for repair templates, both Rad51 and Dmc1 are required for interhomolog...

Data from: Two decades of genetic profiling yields first evidence of natal philopatry and long-term fidelity to parturition sites in sharks

Kevin A. Feldheim, Samuel H. Gruber, Joseph D. DiBattista, Elizabeth A. Babcock, Steven A. Kessel, Andrew P. Hendry, Ellen K. Pikitch, Mary V. Ashley & Demian D. Chapman
Sharks are a globally threatened group of marine fishes that often breed in their natal region of origin. There has even been speculation that female sharks return to their exact birthplace to breed (“natal philopatry”), which would have important conservation implications. Genetic profiling of lemon sharks (Negaprion brevirostris) from 20 consecutive cohorts (1993-2012) at Bimini, Bahamas showed that certain females faithfully gave birth at this site for nearly two decades. At least six females born...

Data from: Measurement, variation, and scaling of osteocyte lacunae: a case study in birds

Michael D. D'Emic, Roger B. J. Benson & Roger B.J. Benson
Basic issues surrounding osteocyte biology are still poorly understood, including the variability of osteocyte morphology within and among bones, individuals, and species. Several studies have suggested that the volume or shape of osteocytes (or their lacunae) are related to bone and/or organismal growth rate or metabolism, but the nature of this relationship, if any, is unclear. Furthermore, several studies have linked osteocyte lacuna volume with genome size or growth rate and suggested that osteocyte lacuna...

Registration Year

  • 2013

Resource Types

  • Dataset


  • Stony Brook University
  • North Carolina State University
  • University of Pennsylvania
  • Field Museum of Natural History
  • University of California System
  • North Carolina Museum of Natural Sciences
  • McGill University
  • King Abdullah University of Science and Technology
  • Charles University
  • University of Miami