17 Works

Data from: Comparing radiomic classifiers and classifier ensembles for detection of peripheral zone prostate tumors on T2-weighted MRI: a multi-site study

Satish E. Viswanath, Prathyush V. Chirra, Michael C. Yim, Neil M. Rofsky, Andrei S. Purysko, Mark A. Rosen, Nicolas B. Bloch & Anant Madabhushi
Background: For most computer-aided diagnosis (CAD) problems involving prostate cancer detection via medical imaging data, the choice of classifier has been largely ad hoc, or been motivated by classifier comparison studies that have involved larger synthetic datasets. More significantly, it is currently unknown how classifier choices and trends generalize across multiple institutions, due to heterogeneous acquisition and intensity characteristics (especially when considering MR imaging data). In this work, we empirically evaluate and compare a number...

Data from: Competitive growth in a social fish

Cymone Reed, Rebecca Branconi, John Majoris, Cara Johnson & Peter Buston
Many animal societies have dominance hierarchies in which social rank is correlated with size. In such societies, the growth and size of individuals can be a strategic response to their social environment: in fishes, individuals may decrease their growth rate to remain small and retain a subordinate position; in mammals, individuals may increase their growth rate to become large and attain a dominant position — a strategy called competitive growth. Here, we investigate whether the...

Data from: Early predictors of outcomes of hospitalization for cirrhosis and assessment of the impact of race and ethnicity at safety-net hospitals

, Samuel Akinyeye, Zachary Fricker, Moinuddin Syed, Eric Orman, Lauren Nephew, Eduardo Vilar Gomez, James Slaven, Naga Chalasani, Maya Balakrishnan, Michelle Long, Bashar Attar & Marwan Ghabril
Background. Safety-net hospitals provide care for racially/ethnically diverse and disadvantaged urban populations. Their hospitalized patients with cirrhosis are relatively understudied and may be vulnerable to poor outcomes and racial/ethnic disparities. Aims. To examine the outcomes of patients with cirrhosis hospitalized at regionally diverse safety-net hospitals and the impact of race/ethnicity. Methods. A study of patients with cirrhosis hospitalized at 4 safety-net hospitals in 2012 was conducted. Demographic, clinical factors, and outcomes were compared between centers...

Data from: Sex-biased lncRNAs inversely correlate with sex-opposite gene co-expression networks in diversity outbred mouse liver

Tisha Melia & David J. Waxman
Sex differences in liver gene expression are determined by pituitary growth hormone secretion patterns, which regulate sex-dependent liver transcription factors and establish sex-specific chromatin states. Hypophysectomy (hypox) identifies two major classes of liver sex-biased genes, defined by their sex-dependent positive or negative responses to pituitary hormone ablation; however, the mechanisms that underlie each hypox-response class are unknown. Here, we sought to discover candidate regulatory long noncoding RNAs (lncRNAs) controlling responsiveness to hypophysectomy. We characterized gene...

Data from: Trails-as-transects: phenology monitoring across heterogeneous microclimates in Acadia National Park, Maine

Caitlin McDonough MacKenzie, Abraham J. Miller-Rushing & Richard B. Primack
Climate‐driven shifts in phenology, which are being observed worldwide, affect ecosystem services, trophic interactions, and community composition, presenting challenges to managers in protected areas. Resource management benefits from local, species‐specific phenology information. However, phenology monitoring programs in heterogeneous landscapes typically require serendipitous historical records or many years of contemporary data before trends in phenological responses to changes in climate can be analyzed. Here, we used a trails‐as‐transects approach to rapidly accumulate monitoring data across environmental...

Persistence of an endangered native duck, feral mallards, and multiple hybrid swarms across the main Hawaiian Islands

Caitlin Wells, Philip Lavretsky, Michael Sorenson, Jeffrey Peters, Jeffrey DaCosta, Stephen Turnbull, Kimberly Uyehara, Christopher Malachowski, Bruce Dugger, John Eadie & Andrew Engilis
Interspecific hybridization is recognized as an important process in the evolutionary dynamics of both speciation and the reversal of speciation. However, our understanding of the spatial and temporal patterns of hybridization that erode versus promote species boundaries is incomplete. The endangered, endemic koloa maoli (or Hawaiian duck, Anas wyvilliana) is thought to be threatened with genetic extinction through ongoing hybridization with an introduced congener, the feral mallard (A. platyrhynchos). We investigated spatial and temporal variation...

Data from: Primary dermal fibroblasts and pectoralis muscle show similar patterns of oxidative stress in tropical and temperate birds despite differing life-histories

Ana Jimenez, Ursula Beattie & Haviland Wright
Tropical birds have a “slower pace of life,” with lower rates of whole-animal metabolism, smaller metabolically active organs, and lower cellular metabolic rates than their temperate counterparts. Oxidative stress is a physiological mechanism that may dictate differing life-histories such as those found between tropical and temperate birds. Oxygen is required to make ATP, resulting in the production of reactive oxygen species (ROS). If left unchecked, ROS can structurally alter proteins, induce mutations in DNA, and...

Airborne polychlorinated biphenyl congeners limits of detection using polyurethane foam passive air samplers

Andres Martinez, Andrew M Awad, Nicholas J Herkert, Wendy J Heiger-Bernays, Madeleine K Scammell & Keri C Hornbuckle
Determination of LOQ for individual PCB congeners obtained from 13 and 5 blank PUFs for sampling periods 1-3 and sampling period 4, respectively, analyzed as samples

Data from: Patterns, dynamics and consequences of microplastic ingestion by the temperate coral, Astrangia poculata

Randi D. Rotjan, Koty H. Sharp, Anna E. Gauthier, Rowan Yelton, Eliya M Baron Lopez, Jessica Carilli, Jonathan C. Kagan & Juanita Urban-Rich
Microplastics (less than 5 mm) are a recognized threat to aquatic food webs because they are ingested at multiple trophic levels and may bioaccumulate. In urban coastal environments, high densities of microplastics may disrupt nutritional intake. However, behavioural dynamics and consequences of microparticle ingestion are still poorly understood. As filter or suspension feeders, benthic marine invertebrates are vulnerable to microplastic ingestion. We explored microplastic ingestion by the temperate coral Astrangia poculata. We detected an average...

Causal links between parietal alpha activity and spatial auditory attention

Yuqi Deng, Robert MG Reinhart, Inyong Choi & Barbara G Shinn-Cunningham
Both visual and auditory spatial selective attention result in lateralized alpha (8-14 Hz) oscillatory power in parietal cortex: alpha increases in the hemisphere ipsilateral to attentional focus. Brain stimulation studies suggest a causal relationship between parietal alpha and suppression of the representation of contralateral visual space. However, there is no evidence that parietal alpha controls auditory spatial attention. Here, we performed high definition transcranial alternating current stimulation (HD-tACS) on human subjects performing an auditory task...

Airborne polychlorinated biphenyl congeners effective volumes collected using polyurethane foam passive air samplers from New Bedford, MA, 2015-2016

Andres Martinez, Andrew M Awad, Nicholas J Herkert, Wendy J Heiger-Bernays, Madeleine K Scammell & Keri C Hornbuckle
Individual PCB congener effective volume (m3) (Herkert et al., 2016)

Data from: Phenological mismatch with trees reduces wildflower carbon budgets

J. Mason Heberling, Caitlin McDonough MacKenzie, Jason D. Fridley, Susan Kalisz & Richard B. Primack
Interacting species can respond differently to climate change, causing unexpected consequences. Many understory wildflowers in deciduous forests leaf out and flower in the spring when light availability is highest before overstory canopy closure. Therefore, different phenological responses by understory and overstory species to increased spring temperature could have significant ecological implications. Pairing contemporary data with historical observations initiated by Henry David Thoreau (1850s), we found that overstory tree leaf out is more responsive to increased...

How do red-eyed treefrog embryos sense motion in predator attacks? Assessing the role of vestibular mechanoreception

Julie Jung, Su J. Kim, Sonia M. Pérez Arias, James G. McDaniel & Karen M. Warkentin
The widespread ability to alter hatching timing in response to environmental cues can serve as a defense against threats to eggs. Arboreal embryos of red-eyed treefrogs, Agalychnis callidryas, hatch up to 30% prematurely to escape predation. This escape-hatching response is cued by physical disturbance of eggs during attacks, including vibrations or motion, and thus depends critically on mechanosensory ability. Predator-induced hatching appears later in development than flooding-induced, hypoxia-cued hatching; thus, its onset is not constrained...

Airborne polychlorinated biphenyl congeners masses from New Bedford, MA, 2015-2016 measured in the polyurethane foam passive air samplers

Andres Martinez, Andrew M Awad, Nicholas J Herkert, Wendy J Heiger-Bernays, Madeleine K Scammell & Keri C Hornbuckle
Individual PCB congener mass detected in polyurethane foam passive air sampler (i.e., PUF-PAS) using GC-MS/MS

Airborne polychlorinated biphenyl congener concentrations collected using polyurethane foam passive air samplers from New Bedford, MA, 2015-2016

Andres Martinez, Andrew M Awad, Nicholas J Herkert, Wendy J Heiger-Bernays, Madeleine K Scammell & Keri C Hornbuckle
Individual PCB congener in air using polyurethane foam passive air sampler (i.e., PUF-PAS)

Airborne polychlorinated biphenyl congener concentrations from New Bedford, MA, 2015-2016

Andres Martinez, Andrew M Awad, Nicholas J Herkert, Wendy J Heiger-Bernays, Madeleine K Scammell & Keri C Hornbuckle
We report the levels of airborne PCB concentrations at 18 locations for three consecutive periods, from July to November of 2015, and one extra period from July to August of 2016 in New Bedford, Fairhaven, Dartmouth, and Acushnet, MA, USA. Measurements were obtained using polyurethane foam passive air samplers (PUF-PAS), deployed for ~40 days. Effective volumes for individual PCB congeners were calculated from a previously published model and included here. Further, the limit of detection...

Data from: Lifestyle and socio-economic inequalities in diabetes prevalence in South Africa: a decomposition analysis

Chipo Mutyambizi, Frederik Booysen, Andrew Stokes, Milena Pavlova & Wim Groot
Background: Inequalities in diabetes are widespread and are exacerbated by differences in lifestyle. Many studies that have estimated inequalities in diabetes make use of self-reported diabetes which is often biased by differences in access to health care and diabetes awareness. This study adds to this literature by making use of a more objective standardised measure of diabetes in South Africa. The study estimates socio-economic inequalities in undiagnosed diabetes, diagnosed diabetes (self-reported), as well as total...

Registration Year

  • 2019

Resource Types

  • Dataset
  • Collection


  • Boston University
  • University of Iowa
  • University of Maine
  • University of Pennsylvania
  • Boston Biomedical (United States)
  • New England Aquarium
  • Oregon State University
  • Roger Williams University
  • Indiana University
  • University of Tennessee at Knoxville