3 Works

Data from: Systems biology of tissue-specific response to Anaplasma phagocytophilum reveals differentiated apoptosis in the tick vector Ixodes scapularis

Nieves Ayllón, Margarita Villar, Ruth C. Galindo, Katherine M. Kocan, Radek Sima, Juan A. López, Jesús Vázquez, Pilar Alberdi, Alejandro Cabezas-Cruz, Petr Kopáček & José De La Fuente
Anaplasma phagocytophilum is an emerging pathogen that causes human granulocytic anaplasmosis. Infection with this zoonotic pathogen affects cell function in both vertebrate host and the tick vector, Ixodes scapularis. Global tissue-specific response and apoptosis signaling pathways were characterized in I. scapularis nymphs and adult female midguts and salivary glands infected with A. phagocytophilum using a systems biology approach combining transcriptomics and proteomics. Apoptosis was selected for pathway-focused analysis due to its role in bacterial infection...

Data from: Colonization of the Mediterranean Basin by the vector biting midge species Culicoides imicola: an old story

Stephanie Jacquet, Claire Garros, Eric Lombaert, Catherine Walton, Johana Restrepo, Xavier Allene, Thierry Baldet, Catherine Cetre-Sossah, Alexandra Chaskopoulou, Jean-Claude Delecolle, Amelie Desvars, Mouloud Djerbal, Moussa Fall, Laetitia Gardes, Michel De Garine-Wichatitsky, Maria Goffredo, Yuval Gottlieb, Assane Gueye Fall, Muo Kasina, Karien Labuschagne, Youssef Lhor, Javier Lucientes, Thibaud Martin, Bruno Mathieu, Miguel Miranda … & J.-C. Delecolle
Understanding the demographic history and genetic make-up of colonizing species is critical for inferring population sources and colonization routes. This is of main interest for designing accurate control measures in areas newly colonized by vector species of economically important pathogens. The biting midge Culicoides imicola is a major vector of orbiviruses to livestock. Historically, the distribution of this species was limited to the Afrotropical region. Entomological surveys first revealed the presence of C. imicola in...

Data from: Gut microbiome composition and metabolomic profiles of wild western lowland gorillas (Gorilla gorilla gorilla) reflect host ecology

Andres Gomez, Klara Petrzelkova, Carl J. Yeoman, Klara Vlckova, Jakub Mrázek, Ingrid Koppova, Franck Carbonero, Alexander Ulanov, David Modry, Angelique Todd, Manolito Torralba, Karen Nelson, H. Rex Gaskins, Brenda Wilson, Rebecca M. Stumpf, Bryan A. White, Steven R. Leigh & Karen E. Nelson
The metabolic activities of gut microbes significantly influence host physiology; thus, characterizing the forces that modulate this micro-ecosystem is key to understanding mammalian biology and fitness. To investigate the gut microbiome of wild primates and determine how these microbial communities respond to the host's external environment, we characterized faecal bacterial communities and, for the first time, gut metabolomes of four wild lowland gorilla groups in the Dzanga-Sangha Protected Areas, Central African Republic. Results show that...

Registration Year

  • 2015
    3

Resource Types

  • Dataset
    3

Affiliations

  • Institute of Parasitology
    3
  • Kenya Agricultural and Livestock Research Organization
    1
  • University of Zaragoza
    1
  • Institute of Animal Physiology and Genetics
    1
  • Oklahoma State University
    1
  • United States Department of Agriculture
    1
  • French National Institute for Agricultural Research
    1
  • University of Manchester
    1
  • French National Centre for Scientific Research
    1
  • Spanish National Research Council
    1