19 Works

Additional file 1 of Barriers and recommendations for a cervical cancer screening program among women in low-resource settings in Lagos Nigeria: a qualitative study

Tope Olubodun, Mobolanle Rasheedat Balogun, Abimbola Kofoworola Odeyemi, Oluwakemi Ololade Odukoya, Adedoyin Oyeyimika Ogunyemi, Oluchi Joan Kanma-Okafor, Ifeoma Peace Okafor, Ayodeji Bamidele Olubodun, Oluwatoyin Olanrewaju Progress Ogundele, Babatunde Ogunnowo & Akin Osibogun
Focus group discussion topic guide.

Barriers and recommendations for a cervical cancer screening program among women in low-resource settings in Lagos Nigeria: a qualitative study

Tope Olubodun, Mobolanle Rasheedat Balogun, Abimbola Kofoworola Odeyemi, Oluwakemi Ololade Odukoya, Adedoyin Oyeyimika Ogunyemi, Oluchi Joan Kanma-Okafor, Ifeoma Peace Okafor, Ayodeji Bamidele Olubodun, Oluwatoyin Olanrewaju Progress Ogundele, Babatunde Ogunnowo & Akin Osibogun
Abstract Background Cervical cancer is the fourth most common cancer in women globally despite being a largely treatable and preventable malignancy. Developing countries account for over 80% of all new cases. Women residing in low-resource settings such as those residing in slums have a higher risk of cervical cancer, and lower uptake of cervical cancer screening. Diverse barriers influence the uptake of cervical cancer screening among women in low-resource settings. Objectives This qualitative study was...

Synthesis and in vitro anticancer activities of substituted N-(4’-Nitrophenyl)-L-prolinamides

Adejoke Osinubi, Josephat Izunobi, Xiaoguang Bao, Olayinka Asekun, Jiehong Kong, Chunshan Gui & Oluwole Familoni
Prolinamides are present in secondary metabolites and have wide-ranging biological properties as well as antimicrobial and cytotoxic activities. N-(4’-substituted phenyl)-L-prolinamides 4a–4w were synthesised in two steps, starting from the condensation of p-fluoronitrobenzene 1a–1b with L-proline 2a–2b, under aqueous–alcoholic basic conditions to afford N-aryl-L-prolines 3a–3c, which underwent amidation via a two-stage, one-pot reaction involving SOCl2 and amines, to furnish L-prolinamides in 20–80% yield. The cytotoxicities of 4a–4w against four human carcinoma cell lines (SGC7901, HCT-116, HepG2...

Barriers and recommendations for a cervical cancer screening program among women in low-resource settings in Lagos Nigeria: a qualitative study

Tope Olubodun, Mobolanle Rasheedat Balogun, Abimbola Kofoworola Odeyemi, Oluwakemi Ololade Odukoya, Adedoyin Oyeyimika Ogunyemi, Oluchi Joan Kanma-Okafor, Ifeoma Peace Okafor, Ayodeji Bamidele Olubodun, Oluwatoyin Olanrewaju Progress Ogundele, Babatunde Ogunnowo & Akin Osibogun
Abstract Background Cervical cancer is the fourth most common cancer in women globally despite being a largely treatable and preventable malignancy. Developing countries account for over 80% of all new cases. Women residing in low-resource settings such as those residing in slums have a higher risk of cervical cancer, and lower uptake of cervical cancer screening. Diverse barriers influence the uptake of cervical cancer screening among women in low-resource settings. Objectives This qualitative study was...

Additional file 1 of High prevalence of resistance to third-generation cephalosporins detected among clinical isolates from sentinel healthcare facilities in Lagos, Nigeria

Emelda E. Chukwu, Oluwatoyin B. Awoderu, Christian A. Enwuru, Ebelechukwu E. Afocha, Rahman G. Lawal, Rahaman A. Ahmed, Ishola Olanrewaju, Chika K. Onwuamah, Rosemary A. Audu & Folasade T. Ogunsola
Additional file 1. Antimicrobial Resistance Surveillance, Checklist for evaluation of competency of study centers.

Additional file 1 of Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Additional file 1. HPLC chromatogram of ethanolic leaf extract of cannabis.

Additional file 1 of Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Additional file 1. HPLC chromatogram of ethanolic leaf extract of cannabis.

Additional file 1 of Barriers and recommendations for a cervical cancer screening program among women in low-resource settings in Lagos Nigeria: a qualitative study

Tope Olubodun, Mobolanle Rasheedat Balogun, Abimbola Kofoworola Odeyemi, Oluwakemi Ololade Odukoya, Adedoyin Oyeyimika Ogunyemi, Oluchi Joan Kanma-Okafor, Ifeoma Peace Okafor, Ayodeji Bamidele Olubodun, Oluwatoyin Olanrewaju Progress Ogundele, Babatunde Ogunnowo & Akin Osibogun
Focus group discussion topic guide.

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Udofia A. Inemesit, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Abstract Background Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular function and sperm quality modulation with cannabis in rats. Methodology Twenty-five male Wistar rats were randomly grouped into five: A, B, C, and D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90...

Data from: Assessment of markers of antimalarial drug resistance in Plasmodium falciparum isolates from pregnant women in Lagos, Nigeria

Chimere Obiora Agomo, Wellington Aghoghovwia Oyibo, Colin J. Sutherland, Rachel Hallet & Mary Oguike
Background: The use of antimalarial drugs for prevention and treatment is a major strategy in the prevention of malaria in pregnancy. Although sulphadoxine-pyrimethamine (SP) is currently recommended for intermittent preventive treatment of malaria during pregnancy in Nigeria, previously used drugs for prophylaxis such as chloroquine (CQ) and pyrimethamine are accessible as they are purchased over the counter. This study describes the markers of absence or presence of resistance to quinoline (Pfcrt and Pfmdr 1) and...

Data from: Improving spatial predictions of taxonomic, functional and phylogenetic diversity

Manuela D'Amen, Ruben G. Mateo, Julien Pottier, Wilfried Thuiller, Luigi Maiorano, Loïc Pellissier, Charlotte Ndiribe, Nicolas Salamin & Antoine Guisan
1. In this study, we compare two community modelling approaches to determine their ability to predict the taxonomic, functional and phylogenetic properties of plant assemblages along a broad elevation gradient and at a fine resolution. The first method is the standard stacking individual species distribution modelling (SSDM) approach, which applies a simple environmental filter to predict species assemblages. The second method couples the SSDM and macroecological modelling (MEM - SSDM-MEM) approaches to impose a limit...

On Computational Solution of the Dynamic and Static Behaviour of a Coupled Thermoelastic Timoshenko Beam

Theddeus Tochukwu AKANO & Akintoye O. OYELADE
The Timoshenko beam theory caters for transverse shear deformations, which are more pronounced in short beams. Previous works were examined, and Hamilton’s principle was used in deriving the governing equation. This research considers two dimensions (2-D): heat and displacement response. A more comprehensive mathematical expression that incorporates this 2-D model on the vibration of a coupled Timoshenko thermoelastic beam and axial deformation effect is formulated. The significance of this model will be expressed through its...

Nonlinear Vibration of Multi-Walled Carbon Nanotubes with Initial Curvature Resting on Elastic Foundations in a Nonlinear Thermo-Magnetic Environment

Gbeminiyi Musibau SOBAMOWO, James A. AKANMU, Olurotimi A. ADELEYE, Samuel AKINGBADE & Ahmed Amao YINUSA
The present work focuses on nonlinear dynamics models of multi-walled carbon nanotubes with initial curvature resting on Winkler-Pasternak elastic foundations in a nonlinear thermomagnetic environment using nonlocal elasticity theory. The derived systems of nonlinear vibration models are solved with the aid of the Galerkin decomposition and the homotopy perturbation method. Effects of temperature, magnetic field, multi-layer, and other thermomechanical parameters on the dynamic responses of the slightly curved multi-walled carbon nanotubes are investigated and discussed....

Additional file 1 of Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Udofia A. Inemesit, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Additional file 1. HPLC chromatogram of ethanolic leaf extract of cannabis.

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Abstract Background Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular function and sperm quality modulation with cannabis in rats. Methodology Twenty-five male Wistar rats were randomly grouped into five: A, B, C, and D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90...

Additional file 1 of High prevalence of resistance to third-generation cephalosporins detected among clinical isolates from sentinel healthcare facilities in Lagos, Nigeria

Emelda E. Chukwu, Oluwatoyin B. Awoderu, Christian A. Enwuru, Ebelechukwu E. Afocha, Rahman G. Lawal, Rahaman A. Ahmed, Ishola Olanrewaju, Chika K. Onwuamah, Rosemary A. Audu & Folasade T. Ogunsola
Additional file 1. Antimicrobial Resistance Surveillance, Checklist for evaluation of competency of study centers.

High prevalence of resistance to third-generation cephalosporins detected among clinical isolates from sentinel healthcare facilities in Lagos, Nigeria

Emelda E. Chukwu, Oluwatoyin B. Awoderu, Christian A. Enwuru, Ebelechukwu E. Afocha, Rahman G. Lawal, Rahaman A. Ahmed, Ishola Olanrewaju, Chika K. Onwuamah, Rosemary A. Audu & Folasade T. Ogunsola
Abstract Background Antimicrobial resistance (AMR) in bacterial pathogens is a worldwide concern that demands immediate attention. Most information on AMR originates from high-income countries and little is known about the burden in Africa, particularly Nigeria. Using four sentinel sites (General hospitals) in Lagos State, this study sought to estimate the burden of AMR. Methods This is a hospital-based surveillance using secondary health care centres. Four sites were randomly selected and included in the study. Clinical...

High prevalence of resistance to third-generation cephalosporins detected among clinical isolates from sentinel healthcare facilities in Lagos, Nigeria

Emelda E. Chukwu, Oluwatoyin B. Awoderu, Christian A. Enwuru, Ebelechukwu E. Afocha, Rahman G. Lawal, Rahaman A. Ahmed, Ishola Olanrewaju, Chika K. Onwuamah, Rosemary A. Audu & Folasade T. Ogunsola
Abstract Background Antimicrobial resistance (AMR) in bacterial pathogens is a worldwide concern that demands immediate attention. Most information on AMR originates from high-income countries and little is known about the burden in Africa, particularly Nigeria. Using four sentinel sites (General hospitals) in Lagos State, this study sought to estimate the burden of AMR. Methods This is a hospital-based surveillance using secondary health care centres. Four sites were randomly selected and included in the study. Clinical...

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Abstract Background Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular function and sperm quality modulation with cannabis in rats. Methodology Twenty-five male Wistar rats were randomly grouped into five: A, B, C, and D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90...

Registration Year

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Affiliations

  • University of Lagos
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  • Al Jouf University
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  • University of Ilorin
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  • Damanhour University
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  • Landmark University
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  • Princess Nourah bint Abdulrahman University
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