Data from: Combining landscape genomics and ecological modelling to investigate local adaptation of indigenous Ugandan cattle to East Coast fever
Elia Vajana, Mario Barbato, Licia Colli, Marco Milanesi, Estelle Rochat, Enrico Fabrizi, Christopher Mukasa, Marcello Del Corvo, Charles Masembe, Vincent B. Muwanika, Fredrick Kabi, Tad Stewart Sonstegard, Heather Jay Huson, Riccardo Negrini, NextGen Consortium, Stéphane Joost & Paolo Ajmone-Marsan
East Coast fever (ECF) is a fatal sickness affecting cattle populations of eastern, central, and southern Africa. The disease is transmitted by the tick Rhipicephalus appendiculatus, and caused by the protozoan Theileria parva parva, which invades host lymphocytes and promotes their clonal expansion. Importantly, indigenous cattle show tolerance to infection in ECF-endemically stable areas. Here, the putative genetic bases underlying ECF-tolerance were investigated using molecular data and epidemiological information from 823 indigenous cattle from Uganda....