3,643 Works

Additional file 8 of The global, regional, and national early-onset colorectal cancer burden and trends from 1990 to 2019: results from the Global Burden of Disease Study 2019

Hongfeng Pan, Zeyi Zhao, Yu Deng, Zhifang Zheng, Ying Huang, Shenghui Huang & Pan Chi
Additional file 8: Table S3. Mortality of early-onset colorectal cancer in 1990 and 2019 with AAPC from 2009 and 2019 at countries/territories level, both sexes.

Additional file 9 of The global, regional, and national early-onset colorectal cancer burden and trends from 1990 to 2019: results from the Global Burden of Disease Study 2019

Hongfeng Pan, Zeyi Zhao, Yu Deng, Zhifang Zheng, Ying Huang, Shenghui Huang & Pan Chi
Additional file 9: Table S4. DALY of early-onset colorectal cancer in 1990 and 2019 with AAPC from 2009 and 2019 at countries/territories level, both sexes.

Additional file 1 of CD206+CD68+ mono-macrophages and serum soluble CD206 level are increased in antineutrophil cytoplasmic antibodies associated glomerulonephritis

Xiao-Ning An, Zhao-Nan Wei, Yin-Yin Xie, Jing Xu, Yan Shen, Li-Yan Ni, Hao Shi, Ping-Yan Shen, Wen Zhang & Yong-Xi Chen
Additional file 1: Table S1. Clinical and laboratory presentation of kidney-function adjusted controls. Table S2. PCR primer sequence. Table S3. Clinical and laboratory presentation of disease controls. Figure S1. The original images of Fig. 4E. Figure S2. The original images of Fig. 4G. Figure S3. The original picture of Fig. 4J.

Change lifestyle modification plan/transtheoretical model in non-alcoholic simple fatty liver disease: a pilot randomized study

Lijuan Li, Kun Hou, Mengya Yuan, Yan Zhang & Yang Zhang
Abstract Background Non-alcoholic simple fatty liver disease patients have very low compliance with almost all types of physical activities. A transtheoretical model-oriented lifestyle modification plan awakens the patient’s consciousness in the pre-intention stage. Aim to evaluate whether a management by stages of change plan based on the Transtheoretical Model and Stages of Change promoted behavior change for patients with non-alcoholic simple fatty liver disease. Methods Patients with simple fatty liver diagnosed from July to December...

Additional file 4 of Effectiveness of WeChat-group-based parental health education in preventing unintentional injuries among children aged 0–3: randomized controlled trial in Shanghai

Yuheng Feng, Xueqi Ma, Qi Zhang, Ruo Jiang, Jun Lu, Kaiyue Chen, Huiping Wang, Qinghua Xia, Jicui Zheng, Jingwei Xia & Xiaohong Li
Additional file 4: Table S1. Theclassification and focus of the 30 articles.

Effectiveness of WeChat-group-based parental health education in preventing unintentional injuries among children aged 0–3: randomized controlled trial in Shanghai

Yuheng Feng, Xueqi Ma, Qi Zhang, Ruo Jiang, Jun Lu, Kaiyue Chen, Huiping Wang, Qinghua Xia, Jicui Zheng, Jingwei Xia & Xiaohong Li
Abstract Background Unintentional injuries to children are a major public health problem. The online social media is a potential way to implement health education for caregivers in online communities. Using WeChat, a free and popular social media service in China, this study evaluated the effectiveness of social online community-based parental health education in preventing unintentional injuries in children aged 0–3. Methods We recruited 365 parents from two community health centers in Shanghai and allocated them...

Single-shot lensfree on-chip quantitative phase microscopy with partially coherent LED-illumination

Yang Chen, Xuejuan Wu, Linpeng Lu, Jiahao Wei, Yumin Wu, Qian Chen & Chao Zuo
We propose a single-shot lens-free phase retrieval (SSLFPR) method in a lens-free on-chip microscopy (LFOCM) system based on a partially coherent light emitting diode (LED) illumination. The finite bandwidth (~23.95 nm) of LED illumination is divided into a series of quasi-monochromatic components according to the LED spectrum measured by a spectrometer. When the ‘virtual wavelength scanning’ phase retrieval method is combined with the dynamic phase support constraint, the resolution loss caused by the spatio-temporal partial...

Additional file 1 of Phylogenomics, plastome structure and species identification in Mahonia (Berberidaceae)

Ruchang Tong, Chaoxia Gui, Yu Zhang, Na Su, Xiaoqi Hou, Meng Liu, Zhaoping Yang, Bing Kang, Zhaoyang Chang, Florian Jabbour & Liang Zhao
Additional file 1: Fig. S1. Visualization of alignment of M. bealei RC601 and six outgroups. Mahonia bealei RC601 was used as a reference sequence. Blue represents coding regions, pink represents non-coding regions and gray arrows points at genes. Fig. S2. Comparison of the LSC, IR and SSC boundary regions of plastomes of M. bealei RC601 and six outgroups. Fig. S3. Structural variation between plastomes of ten species of Mahonia revealed by Mauve. Fig. S4. Phylogenetic...

Additional file 1 of Impact of antiretroviral therapy (ART) duration on ART adherence among men who have sex with men (MSM) living with HIV in Jinan of China

Kedi Jiao, Meizhen Liao, Guangmei Liu, Yanmei Bi, Xiuhong Zhao, Qian Chen, Jing Ma, Yu Yan, Chunxiao Cheng, Yijun Li, Wenwen Jia, Lina Wang, Yanwen Cao, Zhonghui Zhao, Xuan Yang, Jing Meng, Jianzhuo Li, Xinrui Li, Chunmei Wang, Dianmin Kang & Wei Ma
Additional file 1. Table S1: Comparison of information about ART missing doses among MSM living with HIV on short-term and long-term ART in Jinan of China (N = 171). Table S2: Comparison of information about ART side effects among MSM living with HIV on short-term and long-term ART in Jinan of China (N = 361). Table S3: Comparison of information about pre-ART adherence education among MSM living with HIV on short-term and long-term ART in...

Comparative chloroplast genome analyses of Amomum: insights into evolutionary history and species identification

Lu Gong, Xiaoxia Ding, Wan Guan, Danchun Zhang, Jing Zhang, Junqi Bai, Wen Xu, Juan Huang, Xiaohui Qiu, Xiasheng Zheng, Danyan Zhang, Shijie Li, Zhihai Huang & He Su
Abstract Background Species in genus Amomum always have important medicinal and economic values. Classification of Amomum using morphological characters has long been a challenge because they exhibit high similarity. The main goals of this study were to mine genetic markers from cp genomes for Amomum species identification and discover their evolutionary history through comparative analysis. Results Three species Amomum villosum, Amomum maximum and Amomum longipetiolatum were sequenced and annotated for the complete chloroplast (cp) genomes,...

The Association Between Child Abuse and Aggressive Behavior: A Three-Level Meta-Analysis

Guangming Ran, Qiongzhi Zhang, Qi Zhang, Jun Li & Jing Chen
Child abuse is considered to be an essential factor in the development of aggressive behavior. The intensity of the positive relations between child abuse and aggressive behavior differed considerably among researches despite the fact that abundant studies have observed this relation. According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach, a three-level meta-analysis was employed to obtain reliable estimates for the sizes of effects and investigate some potential moderators of the...

sj-docx-1-tam-10.1177_17588359221136759 – Supplemental material for Immune checkpoint inhibitors plus chemotherapy in patients with locally advanced or metastatic pulmonary sarcomatoid carcinoma: a multicentric real-world study

Fei Zhou, Haoyue Guo, Xiaolong Zhou, Huikang Xie, Tian Tian, Wencheng Zhao, Guanghui Gao, Anwen Xiong, Lei Wang, Wei Li, Xiaoxia Chen, Yan Zhang, Jue Fan, Fengying Wu, Yongchang Zhang & Caicun Zhou
Supplemental material, sj-docx-1-tam-10.1177_17588359221136759 for Immune checkpoint inhibitors plus chemotherapy in patients with locally advanced or metastatic pulmonary sarcomatoid carcinoma: a multicentric real-world study by Fei Zhou, Haoyue Guo, Xiaolong Zhou, Huikang Xie, Tian Tian, Wencheng Zhao, Guanghui Gao, Anwen Xiong, Lei Wang, Wei Li, Xiaoxia Chen, Yan Zhang, Jue Fan, Fengying Wu, Yongchang Zhang and Caicun Zhou in Therapeutic Advances in Medical Oncology

sj-docx-2-tam-10.1177_17588359221136759 – Supplemental material for Immune checkpoint inhibitors plus chemotherapy in patients with locally advanced or metastatic pulmonary sarcomatoid carcinoma: a multicentric real-world study

Fei Zhou, Haoyue Guo, Xiaolong Zhou, Huikang Xie, Tian Tian, Wencheng Zhao, Guanghui Gao, Anwen Xiong, Lei Wang, Wei Li, Xiaoxia Chen, Yan Zhang, Jue Fan, Fengying Wu, Yongchang Zhang & Caicun Zhou
Supplemental material, sj-docx-2-tam-10.1177_17588359221136759 for Immune checkpoint inhibitors plus chemotherapy in patients with locally advanced or metastatic pulmonary sarcomatoid carcinoma: a multicentric real-world study by Fei Zhou, Haoyue Guo, Xiaolong Zhou, Huikang Xie, Tian Tian, Wencheng Zhao, Guanghui Gao, Anwen Xiong, Lei Wang, Wei Li, Xiaoxia Chen, Yan Zhang, Jue Fan, Fengying Wu, Yongchang Zhang and Caicun Zhou in Therapeutic Advances in Medical Oncology

Additional file 1 of Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage

Qixing Li, Yanpeng Li, Bibo Liang, Rui Xu, Bingze Xu, Erik Lönnblom, Hui Feng, Jing’an Bai, Roma Stawikowska, Changrong Ge, Aiping Lu, Gregg B. Fields, Lianbo Xiao & Rikard Holmdahl
Additional file 1: Supplementary Table S1. Cyclic human COL2 peptide sequences (ACC10 and their corresponding arginine peptides). Amino acids differing from mouse are indicated in italic. Supplementary Table S2. Detailed information of antibody response to ACC10 in different sera subset. Supplementary Table S3. Information of other antigen peptides. Supplementary Table S4. Triple-helical COL2 peptide sequences. Supplementary Table S5. Peptides to which private sera have specific responses. Fig. S1. Some characteristics from patients with promiscuous or...

Realization of all-optical higher-order spatial differentiators based on cascaded operations

yichang Shou, Yan Wang, Lili Miao, Shizhen Chen & Hailu Luo
Cascaded operations play an important role in traditional electronic computing systems for the realization of advanced strategies. Here, we introduce the idea of cascaded operations into all-optical spatial analog computing. The single function of the first-order operation is difficult to meet the requirements of practical applications in image recognition. The all-optical second-order spatial differentiators are implemented by cascading two first-order differential operation units, and the image edge detection of amplitude and phase objects are demonstrated....

Additional file 1 of Screening of ulcerative colitis biomarkers and potential pathways based on weighted gene co-expression network, machine learning and ceRNA hypothesis

Ying Li, Mengyao Tang, Feng Jun Zhang, Yihan Huang, Jing Zhang, Junqi Li, Yunpeng Wang, Jinguang Yang & Shu Zhu
Additional file 1. The Supplementary Material for this article can be found online at Mendeley Data, V1, DOI: https://doi.org/10.17632/58hf8kz9tm.1

Additional file 1 of mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A

Liang Zhao, Huizhao Su, Xiaomeng Liu, Hongquan Wang, Yukuan Feng, Yan Wang, Haiqiang Chen, Luo Dai, Shihui Lai, Siqi Xu, Chong Li, Jihui Hao & Bo Tang
Additional file 1. Additional methods. Fig. S1. mTOR senses the availability of methionine. Fig. S2. mTORC1 signaling pathway mediated Myc expression to promote HCC tumorigenesis. Fig. S3. Negative correlation of MYC and SIRT4 expression. Fig. S4. Myc regulates SIRT4 stability through proteasome degradation. Fig. S5. Characterization of the interaction between SIRT4 and TRIM32. Fig. S6. SIRT4 suppresses Myc promoted HCC tumorigenesis. Fig. S7. The effect of SIRT4 on histone methylation through regulating methionine metabolism. Fig....

Additional file 1 of mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A

Liang Zhao, Huizhao Su, Xiaomeng Liu, Hongquan Wang, Yukuan Feng, Yan Wang, Haiqiang Chen, Luo Dai, Shihui Lai, Siqi Xu, Chong Li, Jihui Hao & Bo Tang
Additional file 1. Additional methods. Fig. S1. mTOR senses the availability of methionine. Fig. S2. mTORC1 signaling pathway mediated Myc expression to promote HCC tumorigenesis. Fig. S3. Negative correlation of MYC and SIRT4 expression. Fig. S4. Myc regulates SIRT4 stability through proteasome degradation. Fig. S5. Characterization of the interaction between SIRT4 and TRIM32. Fig. S6. SIRT4 suppresses Myc promoted HCC tumorigenesis. Fig. S7. The effect of SIRT4 on histone methylation through regulating methionine metabolism. Fig....

Additional file 2 of mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A

Liang Zhao, Huizhao Su, Xiaomeng Liu, Hongquan Wang, Yukuan Feng, Yan Wang, Haiqiang Chen, Luo Dai, Shihui Lai, Siqi Xu, Chong Li, Jihui Hao & Bo Tang
Additional file 2: Table S1. Detected gene levels upon methionine restriction in livers of HCC mouce models.

mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A

Liang Zhao, Huizhao Su, Xiaomeng Liu, Hongquan Wang, Yukuan Feng, Yan Wang, Haiqiang Chen, Luo Dai, Shihui Lai, Siqi Xu, Chong Li, Jihui Hao & Bo Tang
Abstract Background Exploiting cancer metabolism during nutrient availability holds immense potential for the clinical and therapeutic benefits of hepatocellular carcinoma (HCC) patients. Dietary methionine is a metabolic dependence of cancer development, but how the signal transduction integrates methionine status to achieve the physiological demand of cancer cells remains unknown. Methods Low or high levels of dietary methionine was fed to mouse models with patient-derived xenograft or diethyl-nitrosamine induced liver cancer. RNA sequence and metabolomics were...

Supplementary document for Multiband tunable exciton-induced transparencies: Exploiting both strong and intermediate coupling in a nanocube-hexagonal-nanoplate heterodimer J-aggregates hybrid - 6066463.pdf

Zhiwei Hu, Ximin Cui, Yang Li, Xiaobo Han & huatian hu
Supplement to manuscript

Additional file 1 of Conteltinib (CT-707) in patients with advanced ALK-positive non-small cell lung cancer: a multicenter, open-label, first-in-human phase 1 study

Puyuan Xing, Qian Zhao, Li Zhang, Hanping Wang, Dingzhi Huang, Pei Hu, Yinghui Sun & Yuankai Shi
Additional file 1: Table S1. In vitro potency of crizotinib and conteltinib (CT-707). Table S2. Intracranial response of conteltinib (CT-707) in ALK-positive patients with brain metastasis.

Two-stage treatment for severe spinal kyphotic deformity secondary to tuberculosis: halo-pelvic traction followed by a posterior-only approach correction

Longtao Qi, Yao Zhao, Beiyu Xu, Chunde Li & Yu Wang
Abstract Background and purpose Several surgical procedures are used to treat tuberculous kyphosis. However, the treatment of extreme spinal kyphosis is challenging, and associated with various complications. Halo traction has been used as an adjunctive method in the treatment of severe spinal deformities. However, there are few reports about the effectiveness of halo-pelvic traction (HPT) for the treatment of extreme spinal kyphosis secondary to tuberculosis. This study evaluated the effectiveness of halo-pelvic traction followed by...

Two-stage treatment for severe spinal kyphotic deformity secondary to tuberculosis: halo-pelvic traction followed by a posterior-only approach correction

Longtao Qi, Yao Zhao, Beiyu Xu, Chunde Li & Yu Wang
Abstract Background and purpose Several surgical procedures are used to treat tuberculous kyphosis. However, the treatment of extreme spinal kyphosis is challenging, and associated with various complications. Halo traction has been used as an adjunctive method in the treatment of severe spinal deformities. However, there are few reports about the effectiveness of halo-pelvic traction (HPT) for the treatment of extreme spinal kyphosis secondary to tuberculosis. This study evaluated the effectiveness of halo-pelvic traction followed by...

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