17 Works

Data from: Publication and reporting of clinical trial results: cross sectional analysis across academic medical centers

Ruijun Chen, Nihar R. Desai, Joseph S. Ross, Weiwei Zhang, Katherine H. Chau, Brian Wayda, Karthik Murugiah, Daniel Y. Lu, Amit Mittal & Harlan M. Krumholz
Objective: To determine rates of publication and reporting of results within two years for all completed clinical trials registered in ClinicalTrials.gov across leading academic medical centers in the United States. Design: Cross sectional analysis. Setting: Academic medical centers in the United States. Participants: Academic medical centers with 40 or more completed interventional trials registered on ClinicalTrials.gov. Methods: Using the Aggregate Analysis of ClinicalTrials.gov database and manual review, we identified all interventional clinical trials registered on...

Larval site characteristics of mosquito Aedes aegypti in Rabai, Kenya

Siyang Xia, Hany K. M. Dweck, Joel Lutomiah, Rosemary Sang, Carolyn S. McBride, Noah H. Rose, Diego Ayala & Jeffrey R. Powell
This dataset is described and analyzed in the paper: "Xia, S., Dweck, H. K. M., Lutomiah, J., Sang, R., McBride, C. S., Rose, N. H., Ayala, D., & Powell, J. R. (2021). Larval sites of the mosquito Aedes aegypti formosus in forest and domestic habitats in Africa and the potential association with oviposition evolution. Ecology and Evolution, 00, 1– 17. https://doi.org/10.1002/ece3.8332" The mosquito Ae. aegypti is a major vector of several arboviral diseases. In Africa,...

Supplementary document for Multidimensional quantitative characterization of the tumor microenvironment by multicontrast nonlinear microscopy - 6044388.pdf

Yanping Li, Binglin Shen, Yuan Lu, Jinhui Shi, Zewei Zhao, Huixian Li, Rui Hu, Junle Qu & Liwei Liu
Supplementary Materials

Multidimensional quantitative characterization of the tumor microenvironment by multicontrast nonlinear microscopy

Yanping Li, Binglin Shen, Yuan Lu, Jinhui Shi, Zewei Zhao, Huixian Li, Rui Hu, Junle Qu & Liwei Liu
Characterization of tumor microenvironment features, such as its microstructures, biomolecular metabolism and functional dynamics, may provide essential pathologic information about the tumor, tumor margin, and adjacent normal tissue for early and intraoperative diagnosis. However, it can be particularly challenging to obtain faithful and comprehensive pathological information simultaneously from unperturbed tissues due to the complexity of the microenvironment in organisms. Super-multiplex nonlinear optical imaging system emerged and matured as an attractive tool for acquisition and elucidation...

Data from: Data sharing through an NIH central database repository: a cross-sectional survey of BioLINCC users

Joseph S. Ross, Jessica D. Ritchie, Emily Finn, Nihar R. Desai, Richard L. Lehman, Harlan M. Krumholz & Cary P. Gross
Objective To characterise experiences using clinical research data shared through the National Institutes of Health (NIH)'s Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC) clinical research data repository, along with data recipients’ perceptions of the value, importance and challenges with using BioLINCC data. Design and setting Cross-sectional web-based survey. Participants All investigators who requested and received access to clinical research data from BioLINCC between 2007 and 2014. Main outcome measures Reasons for BioLINCC data...

Larval site characteristics of mosquito Aedes aegypti in La Lope, Gabon

Siyang Xia, Hany K. M. Dweck, Joel Lutomiah, Rosemary Sang, Carolyn S. McBride, Noah H. Rose, Diego Ayala & Jeffrey R. Powell
This dataset is described and analyzed in the paper: "Xia, S., Dweck, H. K. M., Lutomiah, J., Sang, R., McBride, C. S., Rose, N. H., Ayala, D., & Powell, J. R. (2021). Larval sites of the mosquito Aedes aegypti formosus in forest and domestic habitats in Africa and the potential association with oviposition evolution. Ecology and Evolution, 00, 1– 17. https://doi.org/10.1002/ece3.8332" The mosquito Ae. aegypti is a major vector of several arboviral diseases. In Africa,...

Supplementary document for Multidimensional quantitative characterization of the tumor microenvironment by multicontrast nonlinear microscopy - 5944886.pdf

Yanping Li, Binglin Shen, Yuan Lu, Jinhui Shi, Zewei Zhao, Huixian Li, Rui Hu, Junle Qu & Liwei Liu
Supplement 1

Supplementary document for Multidimensional quantitative characterization of the tumor microenvironment by multicontrast nonlinear microscopy - 5944886.pdf

Yanping Li, Binglin Shen, Yuan Lu, Jinhui Shi, Zewei Zhao, Huixian Li, Rui Hu, Junle Qu & Liwei Liu
Supplement 1

Data from: Sharing of clinical trial data among trialists: a cross sectional survey

Vinay Rathi, Kristina Dzara, Cary P. Gross, Iain Hrynaszkiewicz, Steven Joffe, Harlan M. Krumholz, Kelly M. Strait & Joseph S. Ross
Objective: To investigate clinical trialists’ opinions and experiences of sharing of clinical trial data with investigators who are not directly collaborating with the research team. Design and setting: Cross sectional, web based survey. Participants: Clinical trialists who were corresponding authors of clinical trials published in 2010 or 2011 in one of six general medical journals with the highest impact factor in 2011. Main outcome measures: Support for and prevalence of data sharing through data repositories...

Data from: Effect of IV glyburide on adjudicated edema endpoints in the GAMES-RP Trial

W. Taylor Kimberly, Matthew B. Bevers, Rüdiger Von Kummer, Andrew M. Demchuk, Javier M. Romero, Jordan J. Elm, Holly E. Hinson, Bradley J. Molyneaux, J. Marc Simard & Kevin Navin Sheth
Objective: In this secondary analysis of the GAMES-RP trial, we report the effect of IV glyburide on adjudicated, edema-related endpoints. Methods: Blinded adjudicators assigned designations for hemorrhagic transformation, neurological deterioration, malignant edema and edema-related death to patients from the GAMES-RP Phase II randomized controlled trial of IV glyburide for large hemispheric infarct. Rates of these endpoints were compared between treatment arms in the per-protocol sample. In those participants with malignant edema, the effects of treatment...

Top 100-Ranked Clinical Journals' Preprint Policies as of April 23, 2020

Dorothy Massey, Joshua Wallach, Joseph Ross, Michelle Opare & Harlan Krumholz
Objective: To determine the top 100-ranked (by impact factor) clinical journals' policies toward publishing research previously published on preprint servers (preprints). Design: Cross sectional. Main outcome measures: Editorial guidelines toward preprints, journal rank by impact factor. Results: 86 (86%) of the journals examined will consider papers previously published as preprints (preprints), 13 (13%) determine their decision on a case-by-case basis, and 1 (1%) does not allow preprints. Conclusions: We found wide acceptance of publishing preprints...

Supplementary document for Multidimensional quantitative characterization of the tumor microenvironment by multicontrast nonlinear microscopy - 6044388.pdf

Yanping Li, Binglin Shen, Yuan Lu, Jinhui Shi, Zewei Zhao, Huixian Li, Rui Hu, Junle Qu & Liwei Liu
Supplementary Materials

Interdependent phenotypic and biogeographic evolution driven by biotic interactions

Ignacio Quintero & Michael J Landis
Biotic interactions are hypothesized to be one of the main processes shaping trait and biogeographic evolution during lineage diversification. Theoretical and empirical evidence suggests that species with similar ecological requirements either spatially exclude each other, by preventing the colonization of competitors or by driving coexisting populations to extinction, or show niche divergence when in sympatry. However, the extent and generality of the effect of interspecific competition in trait and biogeographic evolution has been limited by...

Supplementary document for Multidimensional quantitative characterization of the tumor microenvironment by multicontrast nonlinear microscopy - 6044388.pdf

Yanping Li, Binglin Shen, Yuan Lu, Jinhui Shi, Zewei Zhao, Huixian Li, Rui Hu, Junle Qu & Liwei Liu
Supplementary Materials

Multidimensional quantitative characterization of the tumor microenvironment by multicontrast nonlinear microscopy

Yanping Li, Binglin Shen, Yuan Lu, Jinhui Shi, Zewei Zhao, Huixian Li, Rui Hu, Junle Qu & Liwei Liu
Characterization of tumor microenvironment features, such as its microstructures, biomolecular metabolism and functional dynamics, may provide essential pathologic information about the tumor, tumor margin, and adjacent normal tissue for early and intraoperative diagnosis. However, it can be particularly challenging to obtain faithful and comprehensive pathological information simultaneously from unperturbed tissues due to the complexity of the microenvironment in organisms. Super-multiplex nonlinear optical imaging system emerged and matured as an attractive tool for acquisition and elucidation...

Multidimensional quantitative characterization of the tumor microenvironment by multicontrast nonlinear microscopy

Yanping Li, Binglin Shen, Yuan Lu, Jinhui Shi, Zewei Zhao, Huixian Li, Rui Hu, Junle Qu & Liwei Liu
Characterization of tumor microenvironment features, such as its microstructures, biomolecular metabolism and functional dynamics, may provide essential pathologic information about the tumor, tumor margin, and adjacent normal tissue for early and intraoperative diagnosis. However, it can be particularly challenging to obtain faithful and comprehensive pathological information simultaneously from unperturbed tissues due to the complexity of the microenvironment in organisms. Super-multiplex nonlinear optical imaging system emerged and matured as an attractive tool for acquisition and elucidation...

Supplementary document for Multidimensional quantitative characterization of the tumor microenvironment by multicontrast nonlinear microscopy - 5944886.pdf

Yanping Li, Binglin Shen, Yuan Lu, Jinhui Shi, Zewei Zhao, Huixian Li, Rui Hu, Junle Qu & Liwei Liu
Supplement 1

Registration Year

  • 2022
    9
  • 2020
    3
  • 2019
    1
  • 2018
    1
  • 2016
    2
  • 2012
    1

Resource Types

  • Dataset
    8
  • Text
    6
  • Collection
    3

Affiliations

  • Yale New Haven Hospital
    17
  • Yale University
    12
  • Sun Yat-sen University
    9
  • Lanzhou Veterinary Research Institute
    9
  • Chinese University of Hong Kong
    9
  • Fudan University
    9
  • Zhongda Hospital Southeast University
    9
  • La Trobe University
    9
  • Shenzhen University
    9
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    9