456 Works

Phytochemical Analysis and Anti-Inflammatory Activity of Nepeta cataria Accessions

Data from: Assessing support for Blaberoidea phylogeny suggests optimal locus

Dominic Evangelista, Sabrina Simon, Megan M. Wilson, Akito Y. Kawahara, Manpreet K. Kohli, Jessica L. Ware, Benjamin Wipfler, Olivier Béthoux, Grandcolas Philippe & Frédéric Legendre
Phylogenomics seeks to use next-generation data to robustly infer an organism’s evolutionary history. Yet, the practical caveats of phylogenomics motivates investigation of improved efficiency, particularly when quality of phylogenies are questionable. To achieve improvements, one goal is to maintain or enhance the quality of phylogenetic inference while severely reducing dataset size. We approach this by assessing which kinds of loci in phylogenomic alignments provide the majority of support for a phylogenetic inference of cockroaches in...

Data from: Multiple factors affect the evolution of repertoire size across birds

Gavin Leighton & Tucker Birmingham
Changes in signaling repertoires across species allow for insight into the macroevolutionary forces that control signaling systems. Signaling systems are theorized to be affected by both the social and ecological environments of species. With respect to social variables, increased social complexity is thought to lead to increased vocal complexity. Although ecology can affect signaling systems in numerous ways, one potential effect of ecology is that more cluttered habitats should lead to greater reliance on non-visual...

Preconception alcohol exposure increases the susceptibility to diabetes in the offspring

Ali Al-Yasari, Shaima Jabbar, Miguel Cabrera, Bénédicte Rousseau & Dipak Sarkar
Preconception alcohol exposure in mothers has recently been shown to increase stress responses and anxiety behaviors in their offspring during the adult period. One hypothesis is that alcohol-induced genetic modifications in germ cells of the mother could have been transmitted to the offspring to manifest the endophenotypes. In this study, transcriptome analysis of germ cells of female rats given binge-like alcohol identified altered stress gene regulation networks involving glucose metabolism and diabetes mellitus. Endocrine tests...

Data from: Pleistocene climatic changes drive diversification across a tropical savanna

Sally Potter, Alexander T. Xue, Jason G. Bragg, Dan F. Rosauer, Emily J. Roycroft & Craig Moritz
Spatial responses of species to past climate change depend on both intrinsic traits (climatic niche breadth, dispersal rates) and the scale of climatic fluctuations across the landscape. New capabilities in generating and analysing population genomic data, along with spatial modelling, have unleashed our capacity to infer how past climate changes have shaped populations, and by extension, complex communities. Combining these approaches, we uncover lineage diversity across four co-distributed lizards from the Australian Monsoonal Tropics and...

Epidemiology and clinical course of COVID-19 in Shanghai, China

Yinzhong Shen, Fang Zheng, Danfeng Sun, Yun Ling, Jun Chen, Feng Li, Tao Li, Zhiping Qian, Yuyi Zhang, Qingnian Xu, Li Liu, Qin Huang, Fei Shan, Lie Xu, Jun Wu, Zhaoqin Zhu, Zhigang Song, Shenyang Li, Yuxin Shi, Jianliang Zhang, Xueyun Wu, Joshua B. Mendelsohn, Tongyu Zhu & Hongzhou Lu
Background: Novel coronavirus pneumonia (COVID-19) is prevalent around the world. We aimed to describe epidemiological features and clinical course in Shanghai. Methods: We retrospectively analysed 325 cases admitted at Shanghai Public Health Clinical Center, between January 20 and February 29, 2020. Results: 47.4% (154/325) had visited Wuhan within 2 weeks of illness onset. 57.2% occurred in 67 clusters; 40% were situated within 53 family clusters. 83.7% developed fever during the disease course. Median times from...

Data from: Costs and benefits of non-random seed release for long distance dispersal in wind-dispersed plant species

Jelle Treep, Monique De Jager, Leandra S. Kuiper, Tomer Duman, Gabriel G. Katul & Merel B. Soons
The dispersal ability of plants is a major factor driving ecological responses to global change. In wind-dispersed plant species, non-random seed release in relation to wind speeds has been identified as a major determinant of dispersal distances. However, little information is available about the costs and benefits of non-random abscission and the consequences of timing for dispersal distances. We asked: 1) To what extent is non-random abscission able to promote long-distance dispersal and what is...

Attitudes about marijuana use, potential risks, and legalization: a single-center survey of pregnant women

June H. Ng, Komal K. Rice, Cande V. Ananth & Justin S. Brandt
There is an association between recreational marijuana use in pregnancy and legalization. As more states legalize marijuana, its use in pregnancy may increase. The objective of this study was to evaluate pregnant women’s knowledge and opinions about marijuana use, potential risks, and legalization. A cross-sectional survey of pregnant women at a regional perinatal center in New Jersey was performed from January-December 2019. Pregnant subjects were invited to complete a voluntary, anonymous 23-question survey about marijuana...

SARS-CoV-2 spike produced in insect cells elicits high neutralization titres in non-human primates

Tingting Li, Qingbing Zheng, Hai Yu, Dinghui Wu, Wenhui Xue, Hualong Xiong, Xiaofen Huang, Meifeng Nie, Mingxi Yue, Rui Rong, Sibo Zhang, Yuyun Zhang, Yangtao Wu, Shaojuan Wang, Zhenghui Zha, Tingting Chen, Tingting Deng, Yingbin Wang, Tianying Zhang, Yixin Chen, Quan Yuan, Qinjian Zhao, Jun Zhang, Ying Gu, Shaowei Li … & Ningshao Xia
The current coronavirus disease 2019 (COVID-19) pandemic was the result of the rapid transmission of a highly pathogenic coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), for which there is no efficacious vaccine or therapeutic. Toward the development of a vaccine, here we expressed and evaluated as potential candidates four versions of the spike (S) protein using an insect cell expression system: receptor binding domain (RBD), S1 subunit, the wild-type S ectodomain (S-WT), and the...

SARS-CoV-2 spike produced in insect cells elicits high neutralization titres in non-human primates

Tingting Li, Qingbing Zheng, Hai Yu, Dinghui Wu, Wenhui Xue, Hualong Xiong, Xiaofen Huang, Meifeng Nie, Mingxi Yue, Rui Rong, Sibo Zhang, Yuyun Zhang, Yangtao Wu, Shaojuan Wang, Zhenghui Zha, Tingting Chen, Tingting Deng, Yingbin Wang, Tianying Zhang, Yixin Chen, Quan Yuan, Qinjian Zhao, Jun Zhang, Ying Gu, Shaowei Li … & Ningshao Xia
The current coronavirus disease 2019 (COVID-19) pandemic was the result of the rapid transmission of a highly pathogenic coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), for which there is no efficacious vaccine or therapeutic. Toward the development of a vaccine, here we expressed and evaluated as potential candidates four versions of the spike (S) protein using an insect cell expression system: receptor binding domain (RBD), S1 subunit, the wild-type S ectodomain (S-WT), and the...

Data from: Temporal scale-dependence of plant-pollinator networks

Benjamin Schwarz, Diego Vázquez, Paul CaraDonna, Tiffany Knight, Gita Benadi, Carsten Dormann, Benoit Gauzens, Elena Motivans, Julian Resasco, Nico Blüthgen, Laura Burkle, Qiang Fang, Christopher Kaiser-Bunbury, Ruben Alarcón, Justin Bain, Natacha Chacoff, Shuang-Quan Huang, Gretchen LeBuhn, Molly MacLeod, Theodora Petanidou, Claus Rasmussen, Michael Simanonok, Amibeth Thompson, Daniel Cariveau, Michael Roswell … & Jochen Fründ
The study of mutualistic interaction networks has led to valuable insights into ecological and evolutionary processes. However, our understanding of network structure may depend upon the temporal scale at which we sample and analyze network data. To date, we lack a comprehensive assessment of the temporal scale-dependence of network structure across a wide range of temporal scales and geographic locations. If network structure is temporally scale-dependent, networks constructed over different temporal scales may provide very...

Data from: Ecological mechanisms and phylogeny shape invertebrate stoichiometry: a test using detritus-based communities across Central and South America

Angélica L. González, Régis Céréghino, Olivier Dézerald, Vinicius F. Farjalla, Céline Leroy, Barbara A. Richardson, Michael J. Richardson, Gustavo Q. Romero & Diane S. Srivastava
1. Stoichiometric differences among organisms can affect trophic interactions and rates of nutrient cycling within ecosystems. However, we still know little about either the underlying causes of these stoichiometric differences, or the consistency of these differences across large geographic extents. 2. Here we analyze elemental (carbon, nitrogen, phosphorus) composition of 872 aquatic macroinvertebrates (71 species) inhabiting tank bromeliads (n = 140) from five distantly located sites across Central and South America to (1) test phylogenetic,...

Data from: Prey diversity, prey composition, and predator population dynamics in experimental microcosms

Owen L. Petchey
1. Food‐web complexity‐stability relations are central to ecology, and many empirical studies show greater food‐web complexity leads to lower population stability. Here, predator population variability decreased with increasing prey diversity in aquatic microcosm experiments, an example of greater food‐web complexity leading to greater population stability. 2. Prey diversity as well as different sets of prey species within each level of prey diversity produced differences in predator population dynamics, demonstrating the importance of both prey composition...

Long non-coding RNA XIST promotes the progression of esophageal squamous cell carcinoma through sponging miR-129-5p and upregulating CCND1 expression

Haoran Wang, Haomiao Li, Yongkui Yu, Qingfeng Jiang, Ruixiang Zhang, Haibo Sun, Wenqun Xing & Yin Li
Long non-coding RNA (lncRNA) X inactive specific transcript (XIST) has been identified as an oncogenic lncRNA in a series of human cancers, including esophageal squamous cell carcinoma (ESCC). In this study, we aimed to further explore the underlying mechanism of XIST on ESCC progression. qRT-PCR assay was used to determine the levels of XIST and miR-129-5p. Western blot analysis was performed to assess cyclin D1 (CCND1) expression. Bioinformatic analysis was performed using starBase v2.0 software....

Data from: Differential effect of selection against LINE retrotransposons among vertebrates inferred from whole-genome data and demographic modeling

Alexander T Xue, Robert P. Ruggiero, Michael J. Hickerson & Stéphane Boissinot
Variation in LINE composition is one of the major determinants for the substantial size and structural differences among vertebrate genomes. In particular, the larger genomes of mammals are characterized by hundreds of thousands of copies from a single LINE clade, L1, whereas nonmammalian vertebrates possess a much greater diversity of LINEs, yet with orders of magnitude less in copy number. It has been proposed that such variation in copy number among vertebrates is due to...

Profitability Analysis of Traditional African Vegetable Seeds Production in Kenya

Henry Myungi, Alaik Laizer, Philipo J. Lukumay, Justus Ochieng, Godfrey Ngoteya, Fekadu Dinssa, James E. Simon, Ramu Govindasamy, Christine Ndinya & Martins Odendo

Access to Multicultural/Multiethnic Grey Literature: A Networked Approach Asian American Resources

Marjorie H. Li
Multicultural/multiethnic GL is a concept first introduced and defined at the GL'95. Multi-cultural/ multiethnic GL, although considered primary resources, have been fragmented and scattered or buried within other reports and documents making them difficult to identify and access. If these materials are to be of any real value, they must be located, organized, and made accessible to the communities they represent as well as to the general public. GL`95 presentations focused on the opportunities presented...

Multicultural/multiethnic grey literature : An Asian-American perspective

Marjorie H. Li
Grey literature while very useful and extremely valuable, unfortunately, may never find its way into the usual review channels. Quite often it is this body of literature - commissioned reports, theses, publications of political activist groups, associations and organizations' newsletters an pamphlets, and ethnic print and non-print media - that are the most useful in recording the history and culture of peoples who have suffered discrimination and exclusion. The Asian-American, as well as the African-American...

Comparison of yield and nutrition of roselle (Hibiscus sabdariffa) genotypes in central New Jersey

Mara Sanders, Albert O. Ayeni & James E. Simon

Additional file 1 of Transcutaneous electrical acupoint stimulation for high-normal blood pressure: study protocol for a randomized controlled pilot trial

Yu Wang, Guang-Xia Shi, Zhong-Xue Tian, Jun-Hong Liu, You-Sheng Qi, Jian-Feng Tu, Jing-Wen Yang, Li-Qiong Wang & Cun-Zhi Liu
Additional file 1. Completed Standard Protocol Items: Recommendation for Interventional Trials (SPIRIT) 2013 Checklist: items addressed in this clinical trial protocol.

Folic acid-modified ROS-responsive nanoparticles encapsulating luteolin for targeted breast cancer treatment

Yu Wang, Qianmei Wang, Wei Feng, Qian Yuan, Xiaowei Qi, Sheng Chen, Pu Yao, Qing Dai, Peiyuan Xia, Dinglin Zhang & Fengjun Sun
Luteolin (Lut) is a natural flavonoid polyphenolic compound with multiple pharmacological activities, such as anti-oxidant, anti-inflammatory, and anti-tumor effects. However, the poor aqueous solubility and low bioactivity of Lut restrict its clinical translation. Herein, we developed a reactive oxygen species (ROS)-responsive nanoplatforms to improve the bioactivity of Lut. Folic acid (FA) was employed to decorate the nanoparticles (NPs) to enhance its targeting ability. The size of Lut-loaded ROS-responsive nanoparticles (Lut/Oxi-αCD NPs) and FA-modified Lut/Oxi-αCD NPs...

Economies of scale shape energetics of solitary and group living spiders and their webs

Samantha Straus, Angélica Gonzalez, Philip Matthews & Leticia Avilés
Metabolic scaling, whereby larger individuals use less energy per unit mass than smaller ones, may apply to the combined metabolic rate of group-living organisms as group size increases. Spiders that form groups in high disturbance environments can serve to test the hypothesis that economies of scale benefit social groups. Using solitary and group-living spiders, we tested the hypothesis that spiders exhibit negative allometry between body or colony mass and the standing mass of their webs...

The economics of direct nitrogen reduction technologies

Gal Hochman

Data from: A population genetic assessment of taxonomic species: the case of Lake Malawi cichlid fishes

Catarina Pinho, Vera Cardoso & Jody Hey
Organisms sampled for population level research are typically assigned to species by morphological criteria. But if those criteria are limited to one sex or life stage, or the organisms come from a complex of closely related forms, the species assignments may misdirect analyses. The impact of such sampling can be assessed from the correspondence of genetic clusters, identified only from patterns of genetic variation, to the species identified using only phenotypic criteria. We undertook this...

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