182 Works

Stop smoking advice by practice assistants after routine cervical screening in general practice: A qualitative exploration of potential barriers and enablers

Marthe B. L. Mansour, Matty R. Crone, Henk C. van Weert, Niels H. Chavannes & Kristel M. van Asselt
Cervical screening could be an appropriate routine moment to provide female smokers with tailored stop smoking advice. In Dutch general practice, cervical smears are performed by practice assistants. This study was performed in preparation for a randomised trial to identify potential barriers and enablers for a brief stop smoking strategy performed by trained practice assistants after routine cervical screening. Between December 2016 and March 2017 three focus group meetings were held with ten practice assistants,...

Additional file 1 of Exogenous ABA and IAA modulate physiological and hormonal adaptation strategies in Cleistocalyx operculatus and Syzygium jambos under long-term waterlogging conditions

El-Hadji Malick Cisse, Juan Zhang, Da-Dong Li, Ling-Feng Miao, Li-Yan Yin & Fan Yang
Additional file 1.

Additional file 5 of Exogenous ABA and IAA modulate physiological and hormonal adaptation strategies in Cleistocalyx operculatus and Syzygium jambos under long-term waterlogging conditions

El-Hadji Malick Cisse, Juan Zhang, Da-Dong Li, Ling-Feng Miao, Li-Yan Yin & Fan Yang
Additional file 5.

Additional file 1 of A 72-channel receive array coil allows whole-heart cine MRI in two breath holds

Hugo Klarenberg, Mark Gosselink, Bram F. Coolen, Tim Leiner, Aart J. Nederveen, Adrianus J. Bakermans, Hildo J. Lamb, S. Matthijs Boekholdt, Martijn Froeling & Gustav J. Strijkers
Additional file 1: Figure S1. Full cardiac cycle animations at apical (slice 3), mid-ventricular (slice 7) and basal (slice 11) short-axis field of views in a male participant. Table S1. Repeated measure comparison of left and right ventricular quantitative variables. Table S2. Linear regression intra-observer contour tracing SENSE=2 16-channel array cine data (Y = a + bx).

Factors associated with formal and informal resource utilization in nursing home patients with and without dementia: cross-sectional analyses from the COSMOS trial

Maarja Vislapuu, Line Iden Berge, Renira C. Angeles, Egil Kjerstad, Janne Mannseth, Wilco P. Achterberg & Bettina S. Husebo
Abstract Objectives To investigate the association between clinical, demographic, and organizational factors and formal (health professionals) and informal (relatives) resource utilization in nursing home patients with and without dementia. Methods Baseline data from the multicomponent cluster randomized control COSMOS trial including 33 Norwegian nursing homes and 723 residents with and without dementia. Nursing home staff (n = 117) participated as proxy raters to approximate formal and informal resource use in daily care. Measurements The primary...

Study protocol of the GLOW study: maximising treatment options for recurrent glioblastoma patients by whole genome sequencing-based diagnostics—a prospective multicenter cohort study

Mark P. van Opijnen, Marike L. D. Broekman, Filip Y. F. de Vos, Edwin Cuppen, Jacobus J. M. van der Hoeven, Myra E. van Linde, Annette Compter, Laurens V. Beerepoot, Martin J. van den Bent, Maaike J. Vos, Helle-Brit Fiebrich, Johan A. F. Koekkoek, Ann Hoeben, Kuan H. Kho, Chantal M. L. Driessen, Hanne-Rinck Jeltema, Pierre A. J. T. Robe & Sybren L. N. Maas
Abstract Background Glioblastoma (GBM), the most common glial primary brain tumour, is without exception lethal. Every year approximately 600 patients are diagnosed with this heterogeneous disease in The Netherlands. Despite neurosurgery, chemo -and radiation therapy, these tumours inevitably recur. Currently, there is no gold standard at time of recurrence and treatment options are limited. Unfortunately, the results of dedicated trials with new drugs have been very disappointing. The goal of the project is to obtain...

Additional file 2 of Structural tissue damage and 24-month progression of semi-quantitative MRI biomarkers of knee osteoarthritis in the IMI-APPROACH cohort

Frank W. Roemer, Mylène Jansen, Anne C. A. Marijnissen, Ali Guermazi, Rafael Heiss, Susanne Maschek, Agnes Lalande, Francisco J. Blanco, Francis Berenbaum, Lotte A. van de Stadt, Margreet Kloppenburg, Ida K. Haugen, Christoph H. Ladel, Jaume Bacardit, Anna Wisser, Felix Eckstein, Floris P. J. G. Lafeber, Harrie H. Weinans & Wolfgang Wirth
Additional file 2.

Additional file 6 of Immune-related 3-lncRNA signature with prognostic connotation in a multi-cancer setting

Shimaa Sherif, Raghvendra Mall, Hossam Almeer, Adviti Naik, Abdulaziz Al Homaid, Remy Thomas, Jessica Roelands, Sathiya Narayanan, Mahmoud Gasim Mohamed, Shahinaz Bedri, Salha Bujassoum Al-Bader, Kulsoom Junejo, Davide Bedognetti, Wouter Hendrickx & Julie Decock
Additional file 6: Prognostic value of ICR classifier across solid cancers. Forest plot showing HRs for death (overall survival) and corresponding 95%-confidence interval for the continuous ICR score and number of patients for each TCGA cancer cohort and RAQA breast cancer cohort. Significant positive HRs are visualized in blue and significant negative HRs are visualized in red. ICR enabled (HR < 1, p-value < 0.05) cancer types are indicated with orange asterisks and ICR disabled...

Additional file 8 of Immune-related 3-lncRNA signature with prognostic connotation in a multi-cancer setting

Shimaa Sherif, Raghvendra Mall, Hossam Almeer, Adviti Naik, Abdulaziz Al Homaid, Remy Thomas, Jessica Roelands, Sathiya Narayanan, Mahmoud Gasim Mohamed, Shahinaz Bedri, Salha Bujassoum Al-Bader, Kulsoom Junejo, Davide Bedognetti, Wouter Hendrickx & Julie Decock
Additional file 8: Survival curves of 3 ir-lncRNA signature. Overall survival Kaplan-Meier curves in which the 3 ir-lncRNAs signature did not show any significant prognostic value. Dichotomization cutoff of ‘high’ (red) and ‘low’ (cyan) subgroups was based on the optimal cut-off point as determined by a 5-fold cross-validation analysis. Censor points are indicated by vertical lines. P-values were determined by logrank test.

Additional file 8 of Immune-related 3-lncRNA signature with prognostic connotation in a multi-cancer setting

Shimaa Sherif, Raghvendra Mall, Hossam Almeer, Adviti Naik, Abdulaziz Al Homaid, Remy Thomas, Jessica Roelands, Sathiya Narayanan, Mahmoud Gasim Mohamed, Shahinaz Bedri, Salha Bujassoum Al-Bader, Kulsoom Junejo, Davide Bedognetti, Wouter Hendrickx & Julie Decock
Additional file 8: Survival curves of 3 ir-lncRNA signature. Overall survival Kaplan-Meier curves in which the 3 ir-lncRNAs signature did not show any significant prognostic value. Dichotomization cutoff of ‘high’ (red) and ‘low’ (cyan) subgroups was based on the optimal cut-off point as determined by a 5-fold cross-validation analysis. Censor points are indicated by vertical lines. P-values were determined by logrank test.

Additional file 1 of Absence of Epstein-Barr virus DNA in anti-citrullinated protein antibody-expressing B cells of patients with rheumatoid arthritis

Sanne Kroos, Arieke S. B. Kampstra, René E. M. Toes, Linda M. Slot & Hans U. Scherer
Additional file 1: Supplementary figure 1. Gating strategy of the isolated ACPA-expressing and IgG memory B cell pools.

Additional file 1 of Absence of Epstein-Barr virus DNA in anti-citrullinated protein antibody-expressing B cells of patients with rheumatoid arthritis

Sanne Kroos, Arieke S. B. Kampstra, René E. M. Toes, Linda M. Slot & Hans U. Scherer
Additional file 1: Supplementary figure 1. Gating strategy of the isolated ACPA-expressing and IgG memory B cell pools.

Additional file 2 of Absence of Epstein-Barr virus DNA in anti-citrullinated protein antibody-expressing B cells of patients with rheumatoid arthritis

Sanne Kroos, Arieke S. B. Kampstra, René E. M. Toes, Linda M. Slot & Hans U. Scherer
Additional file 2: Supplementary figure 2. BNRF1 is undetectable in SF antigen-specific ACPA-expressing B cells. Left: B2M copies in DNA of SF IgG memory B cells and ACPA-expressing B cells as detected by qPCR. Right: no detection of BNRF1 by qPCR in DNA of SF IgG memory B cells, ACPA-expressing B cells and CD40L feeder cells only. Each dot represents a pool of 20 cells isolated directly into lysis buffer, from one donor. qPCR experiments...

Treatment and low-density lipoprotein cholesterol levels in patients with hypercholesterolaemia or mixed dyslipidaemia at high or very high cardiovascular risk: a population-based cross-sectional study in the Netherlands

Edith M. Heintjes, Anastassia Anastassopoulou, Josephina Kuiper, Aikaterini Bilitou, Fernie J.A. Penning-van Beest, Ron M.C. Herings, Maarten J. Postma & J. Wouter Jukema
Objective: To describe treatment patterns, low-density lipoprotein cholesterol (LDL-C) levels and healthcare resource utilization (HCRU) in the Netherlands in 2018 of patients with hypercholesterolaemia or mixed dyslipidaemia at high or very high cardiovascular (CV) risk. Methods: From the PHARMO Database Network adult patients with a diagnosis for hypercholesterolaemia or mixed dyslipidaemia or treated with lipid lowering therapy (LLT) between 2009 and 2018 were selected and the proportion at high or very high CV risk according...

Additional file 5 of Immune-related 3-lncRNA signature with prognostic connotation in a multi-cancer setting

Shimaa Sherif, Raghvendra Mall, Hossam Almeer, Adviti Naik, Abdulaziz Al Homaid, Remy Thomas, Jessica Roelands, Sathiya Narayanan, Mahmoud Gasim Mohamed, Shahinaz Bedri, Salha Bujassoum Al-Bader, Kulsoom Junejo, Davide Bedognetti, Wouter Hendrickx & Julie Decock
Additional file 5: Spearman correlation coefficients of ir-lncRNAs with immune checkpoint expression in TCGA-BRCA.

Additional file 1 of Plasma proteome profiling identifies changes associated to AD but not to FTD

R. Babapour Mofrad, M. del Campo, C. F. W. Peeters, L. H. H. Meeter, H. Seelaar, M. Koel-Simmelink, I. H. G. B. Ramakers, H. A. M. Middelkoop, P. P. De Deyn, J. A. H. R. Claassen, J. C. van Swieten, C. Bridel, J. J. M. Hoozemans, P. Scheltens, W. M. van der Flier, Y. A. L. Pijnenburg & Charlotte E. Teunissen
Additional file 1. Table S1. Distribution of diagnoses over the different centers.

Additional file 1 of Five years’ experience with value-based quality improvement teams: the key factors to a successful implementation in hospital care

Kirsten Daniels, Marc B. V. Rouppe van der Voort, Douwe H. Biesma & Paul B. van der Nat
Additional file 1: Appendix A. Interview guide.

Additional file 2 of Five years’ experience with value-based quality improvement teams: the key factors to a successful implementation in hospital care

Kirsten Daniels, Marc B. V. Rouppe van der Voort, Douwe H. Biesma & Paul B. van der Nat
Additional file 2: Appendix B. Composition of value-based quality improvement (VBQI) teams.

Additional file 4 of In-hospital initiation of PCSK9 inhibitor and short-term lipid control in patients with acute myocardial infarction

Bowen Lou, Hui Liu, Yongbai Luo, Gulinigaer Tuerhong Jiang, Haoyu Wu, Chen Wang, Yue Wu, Bo Zhou, Zuyi Yuan, Jianqing She & Junhui Liu
Additional file 4: Table. S2. Summary of triple therapy-based PSM.

Weekly scarlet fever case data from The dynamics of scarlet fever in The Netherlands, 1906–1920: a historical analysis

Scott A. McDonald, Maarten van Wijhe, Brechje de Gier, Hester Korthals Altes, Bart J. M. Vlaminckx, Susan Hahné & Jacco Wallinga
Weekly scarlet fever case counts for the analysis period.

Supplementary material from \"The dynamics of scarlet fever in The Netherlands, 1906–1920: a historical analysis\"

Scott A. McDonald, Maarten van Wijhe, Brechje de Gier, Hester Korthals Altes, Bart J. M. Vlaminckx, Susan Hahné & Jacco Wallinga
Background. Scarlet fever, an infectious disease caused by Streptococcus pyogenes, largely disappeared in developed countries during the twentieth century. In recent years, scarlet fever is on the rise again, and there is a need for a better understanding of possible factors driving transmission. Methods. Using historical case notification data from the three largest cities in the Netherlands (Amsterdam, Rotterdam and The Hague) from 1906 to 1920, we inferred the transmission rate for scarlet fever using...

Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

Pål Møller, Toni Seppälä, James G. Dowty, Saskia Haupt, Mev Dominguez-Valentin, Lone Sunde, Inge Bernstein, Christoph Engel, Stefan Aretz, Maartje Nielsen, Gabriel Capella, Dafydd Gareth Evans, John Burn, Elke Holinski-Feder, Lucio Bertario, Bernardo Bonanni, Annika Lindblom, Zohar Levi, Finlay Macrae, Ingrid Winship, John-Paul Plazzer, Rolf Sijmons, Luigi Laghi, Adriana Della Valle, Karl Heinimann … & Mark A. Jenkins
Abstract Objective To compare colorectal cancer (CRC) incidences in carriers of pathogenic variants of the MMR genes in the PLSD and IMRC cohorts, of which only the former included mandatory colonoscopy surveillance for all participants. Methods CRC incidences were calculated in an intervention group comprising a cohort of confirmed carriers of pathogenic or likely pathogenic variants in mismatch repair genes (path_MMR) followed prospectively by the Prospective Lynch Syndrome Database (PLSD). All had colonoscopy surveillance, with...

Additional file 2 of Identified or conflicted: a latent class and regression tree analysis explaining how identity constructs cluster within smokers

E. Meijer, W. A. Gebhardt, C. van Laar, N. H. Chavannes & B. van den Putte
Additional file 2: Scores on the explanatory variables in lower, middle and higher SES-groups.

Additional file 1 of Microcirculatory alterations in critically ill COVID-19 patients analyzed using artificial intelligence

Matthias Peter Hilty, Emanuele Favaron, Pedro David Wendel Garcia, Yavuz Ahiska, Zuhre Uz, Sakir Akin, Moritz Flick, Sesmu Arbous, Daniel A. Hofmaenner, Bernd Saugel, Henrik Endeman, Reto Andreas Schuepbach & Can Ince
Additional file 1. Supplementary information.

Additional file 1 of Glycemic control is independently associated with rapid progression of coronary atherosclerosis in the absence of a baseline coronary plaque burden: a retrospective case–control study from the PARADIGM registry

Ki-Bum Won, Byoung Kwon Lee, Fay Y. Lin, Martin Hadamitzky, Yong-Jin Kim, Ji Min Sung, Edoardo Conte, Daniele Andreini, Gianluca Pontone, Matthew J. Budoff, Ilan Gottlieb, Eun Ju Chun, Filippo Cademartiri, Erica Maffei, Hugo Marques, Pedro de Araújo Gonçalves, Jonathon A. Leipsic, Sang-Eun Lee, Sanghoon Shin, Jung Hyun Choi, Renu Virmani, Habib Samady, Kavitha Chinnaiyan, Daniel S. Berman, Jagat Narula … & Hyuk-Jae Chang
Additional file 1: Table S1 Comparison of the annual plaque volume changes for each coronary plaque subtype according to statin use Additional file 2: Table S2 Association of the serum hemoglobin A1C level (per 1% increase) with the annual plaque volume changes for each coronary plaque subtype Additional file 3: Table S3 Univariate logistic regression analysis for the associations of clinical variables with the risk of RPP

Registration Year

  • 2022
    182

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Affiliations

  • Leiden University Medical Center
    182
  • University Medical Center Utrecht
    48
  • Shanghai Jiao Tong University
    33
  • Erasmus MC
    27
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    27
  • University of Science and Technology of China
    27
  • Utrecht University
    27
  • Universitätsklinikum Erlangen
    26
  • University Medical Center Groningen
    22
  • Sun Yat-sen University
    21