64 Works

Fluid-preserved fishes are one solution for assessing historical change in fish trophic level

Rachel Welicky, Terry Rolfe, Karrin Leazer, Katherine Pearson Masklenikov, Luke Tornabene, Gordon Holtgrieve & Chelsea Wood
There are few resources available for assessing historical change in fish trophic dynamics, but specimens held in natural history collections could serve as this resource. In contemporary trophic ecology studies, trophic and source information can be obtained from compound-specific stable nitrogen isotope analysis (CSIA-AA-N). Can this method yield reliable trophic information from chemically-altered fish specimens held in natural history collections? We tested whether CSIA-AA-N can be used on fluid-preserved specimens by experimentally subjecting specimens to...

Dissociable control of unconditioned responses and associative fear learning by parabrachial CGRP neurons

Anna Bowen, Jane Chen, Y. Waterlily Huang, Nathan Baertsch, Sekun Park & Richard Palmiter
Parabrachial CGRP neurons receive diverse threat-related signals and contribute to multiple phases of adaptive threat responses in mice, with their inactivation attenuating both unconditioned behavioral responses to somatic pain and fear-memory formation. Because CGRPPBN neurons respond broadly to multi-modal threats, it remains unknown how these distinct adaptive processes are individually engaged. We show that while three partially separable subsets of CGRPPBN neurons broadly collateralize to their respective downstream partners, individual projections accomplish distinct functions: hypothalamic...

Data from: Evaluating tooth strontium and barium as indicators of weaning age in Pacific walruses

Casey Clark, Lara Horstmann & Nicole Misarti
A dataset of calcium-normalized 88Sr and 137Ba concentrations from laser ablation transects across the cementum layer of 107 (female: n = 84, male: n = 23) Pacific walrus (Odobenus rosmarus divergens) teeth. Dataset includes spreadsheets containing elapsed time of laser ablation transect in seconds (ElapsedTime_s; laser transect speed = 5μm/s), calcium-normalized strontium concentrations (Sr_ppm_m88; values below limit of detection replaced with 1/2*limit of detection, see methods), and calcium-normalized barium concentrations (Ba_ppm_m137; values below limit of...

The Pacific lamprey genomic divergence, association mapping, temporal Willamette Falls, spatial rangewide datasets

Jon Hess, Jeramiah Smith, Nataliya Timoshevskaya, Cyndi Baker, Christopher Caudill, David Graves, Matthew Keefer, Andrew Kinziger, Mary Moser, Laurie Porter, Greg Silver, Steven Whitlock & Shawn Narum
High rates of dispersal can breakdown coadapted gene complexes. However, concentrated genomic architecture (i.e., genomic islands of divergence) can suppress recombination to allow evolution of local adaptations despite high gene flow. Pacific lamprey (Entosphenus tridentatus) is a highly dispersive anadromous fish. Observed trait diversity and evidence for genetic basis of traits suggests it may be locally adapted. We addressed whether concentrated genomic architecture could influence local adaptation for Pacific lamprey. Using two new whole genome...

Data from: Adaptation via pleiotropy and linkage: association mapping reveals a complex genetic architecture within the stickleback Eda locus

Sophie Archambeault, Luis Bärtschi, Aurélie Merminod & Catherine Peichel
Genomic mapping of the loci associated with phenotypic evolution has revealed genomic “hotspots”, or regions of the genome that control multiple phenotypic traits. This clustering of loci has important implications for the speed and maintenance of adaptation and could be due to pleiotropic effects of a single mutation or tight genetic linkage of multiple causative mutations affecting different traits. The threespine stickleback (Gasterosteus aculeatus) is a powerful model for the study of adaptive evolution because...

Early life exposure to environmental contaminants (BDE-47, TBBPA, and BPS) produced persistent gut dysbiosis in adult male mice

Julia Yue Cui, Matthew Gomez, Alexander Suvorov, Xiaojian Shi, Haiwei Gu & Sridhar Mani
The gut microbiome is a pivotal player in toxicological responses. We investigated the effects of maternal exposure to 3 human health-relevant toxicants (BDE-47, TBBPA, and BPS) on the composition and metabolite levels (bile acids [BAs] and short chain fatty acids [SCFAs]) of the gut microbiome in adult pups. CD-1 mouse dams were orally exposed to vehicle (corn oil, 10ml/kg), BDE-47 (0.2 mg/kg), TBBPA (0.2 mg/kg), or BPS (0.2 mg/kg) once daily from gestational day 8...

Genetic structures across a biogeographical barrier reflect dispersal potential of four Southeast Asian mangrove plant species

Alison Wee, Annika Noreen, Junya Ono, Koji Takayama, Prakash Kumar, Hugh Tan, Mohd Saleh, Tadashi Kajita, Edward Webb, Alison K. S. Wee, Annika M. E. Noreen, Prakash P. Kumar, Hugh T. W. Tan, Mohd N. Saleh & Edward L. Webb
Aim Biogeographic barriers restrict the movement of individuals, resulting in population divergence, genetic differentiation, endemism and speciation. Yet, some barriers demonstrate unequal effect across species depending on species dispersal, which manifests in varying genetic structure. We test the hypotheses that the genetic structure of four coastal mangrove species would reflect differences in dispersal potential across the Malay Peninsula, a major biogeographic barrier in the Indo-West Pacific region. Location Twelve sites from the east and west...

Model output for: Attributing causes of future climate change in the California Current System with multi-model downscaling

Evan Howard, Hartmut Frenzel, Fayçal Kessouri, Lionel Renault, Daniele Bianchi, James McWilliams & Curtis Deutsch
Regional Ocean Modeling System outputs from dynamic downscaling of Coupled Model Intercomparison Project climate forcings in the California Current system, including projections with full climate forcings, as well as attribution experiments with only changes in wind, heat fluxes and other properties changing stratification, and boundary biogeochemical forcings. Output variables include euphotic zone integrated net primary productivity, and incident photosytnehtically available radiation, and ocean temperature, salinity, vertical velocity, and dissolved oxygen and nitrate concentrations at select...

Morphometric variation at different spatial scales: coordination and compensation in the emergence of organismal form

Philipp Mitteroecker, Silvester Bartsch, Nicole Grunstra, Anne Le Maitre, Fred Bookstein & Corinna Erkinger
It is a classic aim of quantitative and evolutionary biology to infer genetic architecture and potential evolutionary responses to selection from the variance-covariance structure of measured traits. But a meaningful genetic or developmental interpretation of raw covariances is difficult, and classic concepts of morphological integration do not directly apply to modern morphometric data. Here we present a new morphometric strategy based on the comparison of morphological variation across different spatial scales. If anatomical elements vary...

Mind the gap: natural cleft palates reduce biting performance in bats

Abigail Curtis, Jessica Arbour & Sharlene Santana
Novel morphological traits pose interesting evolutionary paradoxes when they become widespread in a lineage while being deleterious in others. Cleft palate is a rare congenital condition in mammals in which the incisor-bearing premaxilla bones of the upper jaw develop abnormally. However, ∼50% of bat species have natural, nonpathological cleft palates. We used the family Vespertilionidae as a model and linear and geometric morphometrics within a phylogenetic framework to (1) explore evolutionary patterns in cleft morphology,...

Selection on a small genomic region underpins differentiation in multiple color traits between two warbler species

Silu Wang, Sievert Rohwer, Devin De Zwaan, David Toews, Irby Lovette, Jacqueline Mackenzie & Darren Irwin
Speciation is one of the most important processes in biology, yet the study of the genomic changes underlying this process is in its infancy. North American warbler species Setophaga townsendi and S. occidentalis hybridize in a stable hybrid zone, following a period of geographic separation. Genomic differentiation accumulated during geographic isolation can be homogenized by introgression at secondary contact, while genetic regions that cause low hybrid fitness can be shielded from such introgression. Here we...

Central processing of leg proprioception in Drosophila: Physiology and behavior data

Sweta Agrawal, John Tuthill, Evyn Dickinson, Anne Sustar, Pralaksha Gurung, David Shepherd & James Truman
Proprioception, the sense of self-movement and position, is mediated by mechanosensory neurons that detect diverse features of body kinematics. Although proprioceptive feedback is crucial for accurate motor control, little is known about how downstream circuits transform limb sensory information to guide motor output. Here, we investigate neural circuits in Drosophila that process proprioceptive information from the fly leg. We identify three cell-types from distinct developmental lineages that are positioned to receive input from proprioceptor subtypes...

Population genomic response to geographic gradients by widespread and endemic fishes of the Arabian Peninsula

Joseph DiBattista, Pablo Saenz-Agudelo, Marek Piatek, Fernando Cagua, Brian Bowen, John Choat, Luiz Rocha, Michelle Gaither, Jean-Paul Hobbs, Tane Sinclair-Taylor, Jennifer McIlwain, Mark Priest, Camrin Braun, Nigel Hussey, Steven Kessel & Michael Berumen
Genetic structure within marine species may be driven by local adaptation to their environment, or alternatively by historical processes, such as geographic isolation. The gulfs and seas bordering the Arabian Peninsula offer an ideal setting to examine connectivity patterns in coral reef fishes with respect to environmental gradients and vicariance. The Red Sea is characterized by a unique marine fauna, historical periods of desiccation and isolation, as well as environmental gradients in salinity, temperature, and...

Phase resolution of heterozygous sites in diploid genomes is important to phylogenomic analysis under the multispecies coalescent model

Ziheng Yang, Jun Huang, Tomas Flouri, Jeremy Bennett & Adam Leache
Genome sequencing projects routinely generate haploid consensus sequences from diploid genomes, which are effectively chimeric sequences with the phase at heterozygous sites resolved at random. The impact of phasing errors on phylogenomic analyses under the multispecies coalescent (MSC) model is largely unknown. Here we conduct a computer simulation to evaluate the performance of four phase-resolution strategies (the true phase resolution, the diploid analytical integration algorithm which averages over all phase resolutions, computational phase resolution using...

Registration Year

  • 2020
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Affiliations

  • University of Washington
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  • Smithsonian Institution
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  • Monash University
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