88,778 Works

HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms-0

Maria Persico, Arnaud Ceol, Caius Gavrila, Robert Hoffmann, Arnaldo Florio & Gianni Cesareni
Copyright information:Taken from "HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms"BMC Bioinformatics 2005;6(Suppl 4):S21-S21.Published online 1 Dec 2005PMCID:PMC1866386. out in the protein table by entering in the form one of the following: a protein name, a Uniprot or a PDB identifier, a keyword, an InterPro domain or a gene ontology term (top part of the form). Alternatively the search can be carried out on the interaction table...

Comparison of precision of predicted residues using DPA vs

Dengming Ming, Judith D Cohn & Michael E Wall
Fast DPA (see also Fig. 9). The y-axis indicates the fraction of proteins with a precision at least as high as the value on the x-axis (y-values should be read from the top of each step).Copyright information:Taken from "Fast dynamics perturbation analysis for prediction of protein functional sites"http://www.biomedcentral.com/1472-6807/8/5BMC Structural Biology 2008;8():5-5.Published online 30 Jan 2008PMCID:PMC2276503.

QDs consist of a metalloid core and a cap/shell that shields the core and renders the QD bioavailable

Ron Hardman
Copyright information:Taken from "A Toxicologic Review of Quantum Dots: Toxicity Depends on Physicochemical and Environmental Factors"Environmental Health Perspectives 2005;114(2):165-172.Published online 20 Sep 2005PMCID:PMC1367826.This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI. The further addition of biocompatible coatings or functional groups can give the QD a desired bioactivity.

Scattergram of the information content versus the score for the KDEL (see Table 2) retrieving motif

Norman E. Davey, Denis C. Shields & Richard J. Edwards
Copyright information:Taken from "SLiMDisc: short, linear motif discovery, correcting for common evolutionary descent"Nucleic Acids Research 2006;34(12):3546-3554.Published online 19 Jul 2006PMCID:PMC1524906.© 2006 The Author(s) Each blue point on the scattergram is a motif which has been considered by SLiMDisc. The points in green are the top three motifs ranked by the method. The actual SLiM for this dataset is the motif described by the regular expression [KRHQSAP][DENQT]EL.

Factors impacting on recovery from the intensive care unit

L Robert Broomhead & Stephen J Brett
Copyright information:Taken from "Clinical review: Intensive care follow-up – what has it told us?"Critical Care 2002;6(5):411-417.Published online 15 Aug 2002PMCID:PMC137315.Copyright © 2002 BioMed Central Ltd

Trial design (HICMan-CHF)

Frank Peters-Klimm, Thomas Müller-Tasch, Dieter Schellberg, Jochen Gensichen, Christiane Muth, Wolfgang Herzog & Joachim Szecsenyi
Copyright information:Taken from "Rationale, design and conduct of a randomised controlled trial evaluating a primary care-based complex intervention to improve the quality of life of heart failure patients: HICMan (Heidelberg Integrated Case Management)"http://www.biomedcentral.com/1471-2261/7/25BMC Cardiovascular Disorders 2007;7():25-25.Published online 23 Aug 2007PMCID:PMC1995216.

A model of a non-covalent interaction between a PI3K-p110 and a Ras

Michael Hsing, Joel L Bellenson, Conor Shankey & Artem Cherkasov
Copyright information:Taken from "Modeling of cell signaling pathways in macrophages by semantic networks"BMC Bioinformatics 2004;5():156-156.Published online 19 Oct 2004PMCID:PMC528732.Copyright © 2004 Hsing et al; licensee BioMed Central Ltd. The figure was graphed from the developed SN to illustrate the relationships among different agents. The figure visualizes the agents as icons and their relationship as arrows. The left panel illustrates that a PI3K-p110 contains a "Not Bound" Ras-binding site and a "Non-Functional" catalytic domain. The right...

Overproduction of SecB does not cause significant effects on secretion and expression of Yops

Svea Dittmann, Annika Schmid, Susanna Richter, Konrad Trülzsch, Jürgen Heesemann & Gottfried Wilharm
Copyright information:Taken from "The type three secretion chaperone SycO is integrated into the Yop regulatory network and binds to the Yop secretion protein YscM1"http://www.biomedcentral.com/1471-2180/7/67BMC Microbiology 2007;7():67-67.Published online 5 Jul 2007PMCID:PMC1933539. Analogous to the experimental setup described in legend to Fig. 2, SecB was overproduced. (A) Coomassie-stained SDS-PAGE after loading of TCA-precipitated fractions of the culture supernatant. (B) Analysis of the corresponding cell lysates; Coomassie-stained gel (upper panel) and corresponding immunoblots to detect SecB, YopH, and...

The entire organization of transcription units on the genome-2

Hirokazu Kobayashi, Joe Akitomi, Nobuyuki Fujii, Kazuo Kobayashi, Md Altaf-Ul-Amin, Ken Kurokawa, Naotake Ogasawara & Shigehiko Kanaya
Copyright information:Taken from "The entire organization of transcription units on the genome"http://www.biomedcentral.com/1471-2164/8/197BMC Genomics 2007;8():197-197.Published online 28 Jun 2007PMCID:PMC1925097. predicted TUs in the 212 known operons); when we included TUs lacking or gaining one gene of known TUs, this figure rose to 85.8%. The x-axis indicates difference in gene number between predicted transcriptions units and known operons, and the y-axis indicates the number of predicted TUs.

Candidate for elective cricothyroidotomy: morbid obesity; no neck; pendulous overhanging tissue; thyroid cartilage positioned in sternal notch

Christina G Rehm, Sandra M Wanek, Eliot B Gagnon, Slone K Pearson & Richard J Mullins
Copyright information:Taken from "Cricothyroidotomy for elective airway management in critically ill trauma patients with technically challenging neck anatomy"Critical Care 2002;6(6):531-535.Published online 17 Sep 2002http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153438.Copyright © 2002 Rehm et al., licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

Alignment of SCOP families c

Richard Chung & Golan Yona
Copyright information:Taken from "Protein family comparison using statistical models and predicted structural information"BMC Bioinformatics 2004;5():183-183.Published online 25 Nov 2004PMCID:PMC544344.Copyright © 2004 Chung and Yona; licensee BioMed Central Ltd.69.1.10 and c.69.1.12

Characterization of G6PI-induced arthritis

Robert Bockermann, David Schubert, Thomas Kamradt & Rikard Holmdahl
Copyright information:Taken from "Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase"Arthritis Research & Therapy 2005;7(6):R1316-R1324.Published online 20 Sep 2005PMCID:PMC1297579.Copyright © 2005 Bockermann et al.; licensee BioMed Central Ltd. Shown are characteristics of glucose-6-phosphate isomerase (G6PI)-induced arthritis in different genetic backgrounds and major histocompatibility complex (MHC) congenics. DBA/1 mice were immunized intradermally at the base of the tail with the indicated amounts of G6PI emulsified in complete Freund's adjuvant (CFA) to establish a dynamic immunization...

Lipid hydrolysis by surface-displayed lipase in two-phase water-isooctane fermentation system

Heung-Chae Jung, Seok-Joon Kwon & Jae-Gu Pan
Copyright information:Taken from "Display of a thermostable lipase on the surface of a solvent-resistant bacterium, GM730, and its applications in whole-cell biocatalysis"BMC Biotechnology 2006;6():23-23.Published online 19 Apr 2006PMCID:PMC1459859.Copyright © 2006 Jung et al; licensee BioMed Central Ltd. (A) Cell growth of, (B) fatty acids released by, GM730 cells containing pRK415 (●), pJHC13 (▲), pJHC14 (■) and JM109/pJHC11 (◆).

Seroepidemiology of Herpes Simplex virus type 1 and 2 in Western and Southern Switzerland in adults aged 25–74 in 1992–93 : a population-based study-0

Dominique Bünzli, Vincent Wietlisbach, Fabrizio Barazzoni, Roland Sahli & Pascal RA Meylan
Copyright information:Taken from "Seroepidemiology of Herpes Simplex virus type 1 and 2 in Western and Southern Switzerland in adults aged 25–74 in 1992–93 : a population-based study"BMC Infectious Diseases 2004;4():10-10.Published online 17 Mar 2004PMCID:PMC395830.Copyright © 2004 Bünzli et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL....

Locations of RBMs 1–4 in bacterial RNase III polypeptides

Alexandre V. Pertzev & Allen W. Nicholson
Copyright information:Taken from "Characterization of RNA sequence determinants and antideterminants of processing reactivity for a minimal substrate of ribonuclease III"Nucleic Acids Research 2006;34(13):3708-3721.Published online 8 Aug 2006PMCID:PMC1540722.© 2006 The Author(s) Shown is a sequence alignment of four bacterial RNase III polypeptides, indicating the locations of secondary structural elements (highlighted in green) as determined by X-ray crystallography, and also the positions of RBMs 1–4. Noted by each motif is the site of interaction with the minimal...

Exposure assessment paradigm

Jane A. Hoppin, John L. Adgate, Monty Eberhart, Marcia Nishioka & P. Barry Ryan
Copyright information:Taken from "Environmental Exposure Assessment of Pesticides in Farmworker Homes"Environmental Health Perspectives 2006;114(6):929-935.Published online 16 Feb 2006PMCID:PMC1480520.This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI GI, gastrointestinal.

Effects of prenyltransferase inhibitors on estrogen response element-dependent luciferase activity in HELN cells transfected with estrogen receptor (ER) α or ERβ

Philippe Cestac, Guillaume Sarrabayrouse, Claire Médale-Giamarchi, Philippe Rochaix, Patrick Balaguer, Gilles Favre, Jean-Charles Faye & Sophie Doisneau-Sixou
Copyright information:Taken from "Prenylation inhibitors stimulate both estrogen receptor α transcriptional activity through AF-1 and AF-2 and estrogen receptor β transcriptional activity"Breast Cancer Research 2004;7(1):R60-R70.Published online 8 Nov 2004PMCID:PMC1064103.Copyright © 2004 Cestac et al., licensee BioMed Central Ltd. Cells, deprived of estradiol (E2) for 4 days, were co-transfected with the Renilla luciferase plasmid and either HEG0 (full-length ERα), pSG5-REβ (full-length ERβ) or pSG5 (empty vector). Five hours after transfection, cells were treated or not with...

Scattering intensity of non-physically stabilised suspensions in blood

Maryam Mobed Miremadi
For comparative purposes the scattering intensities of non-adsorbed suspensions at c2 are represented. This figure is taken from the thesis 'In-vitro and in-vivo characterization of carboxymethylchitin-coated liposomes' which can be found online here: http://www.collectionscanada.ca/obj/thesescanada/vol1/QMM/TC-QMM-42098.pdf http://digitool.library.mcgill.ca:8881/thesisfile42098.pdf

Production of amplified DNA pseudolibraries and high-throughput cDNA target amplification-0

Daniel Frey, Christian Kambach, Michel O Steinmetz & Rolf Jaussi
Copyright information:Taken from "Production of amplified DNA pseudolibraries and high-throughput cDNA target amplification"BMC Biotechnology 2007;7():31-31.Published online 12 Jun 2007PMCID:PMC1894961.nspected and bands with suitable DNA size were scored (cf. fig. 2). Species identifiers: Hs, Homo sapiens; Gg, Gallus gallus (chicken); Dm, Drsosophila melanogaster; At, Arabidopsis thaliana. Domain abbreviations: Hel, helicase; ATP, ATPase, dsrm, double-stranded RNA-binding motiv. Designations: Species identifier, protein name, short designation of target domain(s).

Relaxin-induced collagenase activity contributes to loss of disc collagen

Tabassum Naqvi, Trang T Duong, Gihan Hashem, Momotoshi Shiga, Qin Zhang & Sunil Kapila
Copyright information:Taken from "Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants"Arthritis Research & Therapy 2004;7(1):R1-R11.Published online 29 Oct 2004PMCID:PMC1064880.Copyright © 2004 Naqvi et al.; licensee BioMed Central Ltd. Conditioned medium from disc incubated with control medium (Ct), β-estradiol (Es), relaxin (R), or β-estradiol plus relaxin (Es+R) in the presence of the matrix metalloproteinase inhibitor GM6001 or its control analog was subjected to fluorescein isothiocyanate-labelled collagen...

DNA demethylation-dependent enhancement of toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription-0

Takashi Furuta, Tsuyoshi Shuto, Shogo Shimasaki, Yuko Ohira, Mary Ann Suico, Dieter C Gruenert & Hirofumi Kai
D as +1.Copyright information:Taken from "DNA demethylation-dependent enhancement of toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription"http://www.biomedcentral.com/1471-2199/9/39BMC Molecular Biology 2008;9():39-39.Published online 21 Apr 2008PMCID:PMC2387165.

Hydrogen-bond pattern and structural vulnerabilities (SEBHs) of the yeast SH3 domain and the human prion protein PrP

Jianping Chen, Han Liang & Ariel Fernández
Hydrogen-bond pattern and structural vulnerabilities (SEBHs) of the yeast SH3 domain from a 40.4 kDa protein (PDB.) []. The ribbon display is included as a visual aid. The protein backbone is shown as virtual bonds (blue) joining consecutive α-carbons in the peptide chain. Light-grey segments represent well protected backbone hydrogen bonds, and green segments represent SEBHs. The extent of solvent-exposure extent of a hydrogen bond was determined from atomic coordinates by calculating the number of...

AFM images of pollen tubes in

Juan-Zi Wu, Yi Lin, Xue-Lian Zhang, Dai-Wen Pang & Jie Zhao
The height images (A, C, E, G) and corresponding phase images (B, D, F, H) in apical region (A–D) and the subapical region (E–H) of control (CON) (A, B, E, F) and IAA-treated pollen tubes (IAA) (C, D, G, H). The growth direction of pollen tubes in all images was upright (as an arrow in A). The block-like structures are outlined with dashes in (C) and (D), and the fibrous structures are indicated with dotted...

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