262,812 Works

MOESM1 of Effect of exercise versus cognitive behavioural therapy or no intervention on anxiety, depression, fitness and quality of life in adults with previous methamphetamine dependency: a systematic review

, Jessica Stander, , Stephanie Eksteen, , & Annemarie Wessels
Additional file 1. Search strategy. Detailed search strategies, specifically developed for each database according its functions.

MOESM6 of Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response

Kenta Iijima, Junya Kobayashi &
Additional file 6: Figure S5. Forced accumulation of Vpr induced DDR in the vicinity of chromatin. aâ e Forced accumulation of Vpr induces phosphorylation of H2AX at Ser139 (a), ATM at Ser1981 (b), RPA32 at Ser33 (c), Rad17 at Ser645 (d), and accumulation of mono- and poly-ubiquitin conjugates (e), on surrounding region.

MOESM3 of Effect of exercise versus cognitive behavioural therapy or no intervention on anxiety, depression, fitness and quality of life in adults with previous methamphetamine dependency: a systematic review

, Jessica Stander, , Stephanie Eksteen, , & Annemarie Wessels
Additional file 3. The PEDro scale. The PEDro scale, including notes on administration (used for methodological appraisal of included studies).

Additional file 8: Figure S6. of A live cell assay of GPCR coupling allows identification of optogenetic tools for controlling Go and Gi signaling

Edward Ballister, Jessica Rodgers, Franck Martial & Robert Lucas
Opsin sensitivity. Selectivity comparison without normalization to rod opsin. a Log10(EC50) values from best-fitting sigmoid curves in Fig. 3d are plotted (see also Additional file 10). EC50 values were compared within each GsX by ANOVA. α = 0.0033 (reflecting Bonferroni correction, 15 comparisons). Asterisks (*) indicate significant differences. b Response amplitudes as shown in Fig. 3d were analyzed by ANOVA, comparing the responses of each Gsi, Gso, and Gst within each opsin, without prior normalization...

MOESM4 of Effect of exercise versus cognitive behavioural therapy or no intervention on anxiety, depression, fitness and quality of life in adults with previous methamphetamine dependency: a systematic review

, Jessica Stander, , Stephanie Eksteen, , & Annemarie Wessels
Additional file 4. Adapted Joanna Briggs Institute Data Extraction Form. Data extraction form, adapted from the standardized Joanna Briggs Institute data extraction form for the purposes of this review.

MOESM4 of Effect of exercise versus cognitive behavioural therapy or no intervention on anxiety, depression, fitness and quality of life in adults with previous methamphetamine dependency: a systematic review

, Jessica Stander, , Stephanie Eksteen, , & Annemarie Wessels
Additional file 4. Adapted Joanna Briggs Institute Data Extraction Form. Data extraction form, adapted from the standardized Joanna Briggs Institute data extraction form for the purposes of this review.

Additional file 1: of Effective nationwide school-based participatory extramural program on adolescent body mass index, health knowledge and behaviors

, Camille Jimenez, Jean Lim, Carmen Isasi, Arthur Blank, David Lounsbury, Lynn Fredericks, Michelle Bouchard, Myles Faith & Judith Wylie
Knowledge and Behavior Domains and Subscales. HealthCorps 2013-2014 survey items and scoring schemes for knowledge, nutrition, physical activity and mental health domains and subscales. (DOCX 28Â kb)

Macrophage polarization and activation at the interface of multi-walled carbon nanotube-induced pulmonary inflammation and fibrosis

Jie Dong & Qiang Ma
Pulmonary exposure to carbon nanotubes (CNTs) induces fibrosing lesions in the lungs that manifest rapid-onset inflammatory and fibrotic responses, leading to chronic fibrosis in animals and health concerns in exposed humans. The mechanisms underlying CNT-induced fibrogenic effects remain undefined. Macrophages are known to play important roles in immune regulation and fibrosis development through their distinct subsets. Here we investigated macrophage polarization and activation in mouse lungs exposed to multi-walled CNTs (MWCNTs). Male C57BL/6J mice were...

Chemical and Biological insights of Ouratea hexasperma (A. St.-Hil.) Baill.: a source of bioactive compounds with multifunctional properties

, Immacolata Faraone, Daniela Russo, Francisco Eduardo Aragão Catunda-Jr, , Mario Geraldo De Carvalho, Nunziatina De Tommasi & Luigi Milella
The study aimed to evaluate in vitro antioxidant, anticholinesterase and antidiabetic properties of Ouratea hexasperma (A. St.-Hil.) Baill. The inflorescence methanol extract and the ethyl acetate fraction of leaves and stems reported the highest Relative Antioxidant Capacity Index (RACI), whereas the dichloromethane fraction of leaves was the best inhibitor of α-amylase and α-glucosidase. Trans-3-O-methyl-resveratrol-2-C-β-glucoside, lithospermoside, 2,5-dimethoxy-p-benzoquinone, lup-20(30)-ene-3β,28-diol, 7-O-methylgenistein, apigenin and luteolin and amentoflavone were isolated from O. hexasperma. Resveratrol derivative was isolated for the first...

Genetic and landscape characterization of ancient autochthonous olive trees in northern Italy

Annalisa Rotondi, , , , , &
Several ancient olive plants with different genetic, agronomic and morphological characteristics are widespread in the Emilia-Romagna region. In this study, details of 206 trees located in four provinces were collected and their phytometric traits were recorded. Easily recognizable varieties were identified, while plants of uncertain genetic identity were submitted for molecular analysis with SSR markers and compared with cultivars widespread in central Italy and Emilia-Romagna. The genetic analyses showed that most of the ancient olive...

MiMA poster at 2nd Pan-GASS meeting, Feb 2018

Martin Jucker
Poster presentation about the Model of an idealized Moist Atmosphere. Presented at the 2nd Pan-GASS meeting in Lorne, Australia in February 2018.

Lenalidomide: A Review in Newly Diagnosed Multiple Myeloma as Maintenance Therapy After ASCT

Compliance with Ethical Standards
Funding: The preparation of this review was not supported by any external funding.
Conflicts of interest: Yahiya Syed is a salaried employee of Adis/Springer, is responsible for the article content and declares no relevant conflicts of interest.
Additional information about this Adis Drug Review can be found here.
Abstract
Lenalidomide (Revlimid®) is an immunomodulatory drug with multiple mechanisms of action against multiple myeloma. It is a thalidomide analogue, with improved potency and reduced toxicity compared...

pathogens_rep_set.fasta

Pu Jia, , Marc W. Cadotte, , Xiang Liu, , , &
This is a dataset about the root-associated pathogen community in a 50ha subtropical forest plot in Southern China

Deutetrabenazine: A Review in Chorea Associated with Huntington’s Disease

& Lesley J. Scott
Compliance with Ethical Standards
Funding: The preparation of this review was not supported by any external funding.
Conflicts of interest: Young-A Heo and Lesley Scott are salaried employee of Adis/Springer, are responsible for the article content and declares no relevant conflicts of interest.
Additional information about this Adis Drug Review can be found here.
Abstract
Oral deutetrabenazine (Austedo™), a reversible inhibitor of vesicular monoamine transporter type 2 (VMAT2) that is structurally related to tetrabenazine is approved for the treatment of...

Additional file 1: of Clinical utility of exome sequencing in individuals with large homozygous regions detected by chromosomal microarray analysis

Aparna Prasad, Matthew Sdano, Rena Vanzo, Patricia Mowery-Rushton, Moises Serrano, Charles Hensel &
A detailed workflow showing the variants discovery and prioritization for the individuals with ROH. (DOCX 29Â kb)

Additional file 1: of Safety and tracking of intrathecal allogeneic mesenchymal stem cell transplantation in healthy and diseased horses

Danielle Barberini, Monica Aleman, Fabio Aristizabal, Mathieu Spriet, Kaitlin Clark, Naomi Walker, Larry Galuppo, Rogério Amorim, Kevin Woolard & Dori Borjesson
Representative image of equine ASC phenotype. Equine ASC phenotype panel. Positive markers: CD44, CD29, CD90, and MHC I. Negative markers: F6B and MHC II. (JPEG 46 kb)

Additional file 2: of Safety and tracking of intrathecal allogeneic mesenchymal stem cell transplantation in healthy and diseased horses

Danielle Barberini, Monica Aleman, Fabio Aristizabal, Mathieu Spriet, Kaitlin Clark, Naomi Walker, Larry Galuppo, Rogério Amorim, Kevin Woolard & Dori Borjesson
Representative images of neurologic patients, spinal cord cross-sections, H&E stain. A) Several dilated myelin sheathes are evident that B) contain macrophages consistent with digestion chambers (arrows). C) Swollen axons are present with spheroid formation (*). D) Multifocal glial nodules (arrowhead) are present within the white matter. Scale bar = 100 μm. (JPEG 92 kb)

Additional file 4: of Clinical utility of exome sequencing in individuals with large homozygous regions detected by chromosomal microarray analysis

Aparna Prasad, Matthew Sdano, Rena Vanzo, Patricia Mowery-Rushton, Moises Serrano, Charles Hensel &
Details of rare homozygous variants discovered in 74% (39/53) of the ROH cases that has variants relevant or potentially relevant to the phenotype of the patient. (XLSX 32Â kb)

Additional file 2: of Safety and tracking of intrathecal allogeneic mesenchymal stem cell transplantation in healthy and diseased horses

Danielle Barberini, Monica Aleman, Fabio Aristizabal, Mathieu Spriet, Kaitlin Clark, Naomi Walker, Larry Galuppo, Rogério Amorim, Kevin Woolard & Dori Borjesson
Representative images of neurologic patients, spinal cord cross-sections, H&E stain. A) Several dilated myelin sheathes are evident that B) contain macrophages consistent with digestion chambers (arrows). C) Swollen axons are present with spheroid formation (*). D) Multifocal glial nodules (arrowhead) are present within the white matter. Scale bar = 100 μm. (JPEG 92 kb)

Additional file 2: of Comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in chemoprevention of hepatocellular carcinoma: a nationwide high-risk cohort study

, , , Jun-Fu Zhang, , &
List of HBV and HCV medications, diagnostic criteria of liver cirrhosis, hyperlipidemia, and alcohol consumption. (DOCX 18 kb)

Additional file 3: of Characterizing oral microbial communities across dentition states and colonization niches

Matthew Mason, Stephanie Chambers, , &
Supplemental Figure S1: Functional shifts in the core salivary microbiome during various dentition states. Figure 1a shows a Bland-Altman plot of changes in the relative abundance of core functional genes in the salivary microbiome between the different dentitions. Each point is a functional gene. Points above and below the red median line represent genes demonstrating higher abundances in the specified dentition. Red points indicate genes with significantly different abundances (p < 0.05, FDR adjusted Wald...

Additional file 3: of Endoscopic submucosal injection of adipose-derived mesenchymal stem cells ameliorates TNBS-induced colitis in rats and prevents stenosis

Eduardo Martín Arranz, María Martín Arranz, Tomás Robredo, Pablo Mancheño-Corvo, Ramón Menta, Francisco Alves, Jose Suárez De Parga, Pedro Mora Sanz, Olga De La Rosa, Dirk Büscher, Eleuterio Lombardo & Fernando De Miguel
Figure S3. The endoscopic score correlation with the colon length 2. (PPTX 37 kb)

Relational continuity with primary and secondary care doctors: a qualitative study of perceptions of users of the Catalan national health system

Sina Waibel, Ingrid Vargas, Jordi Coderch &
Abstract Background In the current context of increasingly fragmented healthcare systems where patients are seen by multiple doctors in different settings, patients’ relational continuity with one doctor is regaining relevance; however little is known about relational continuity with specialists. The aim of this study is to explore perceptions of relational continuity with primary care and secondary care doctors, its influencing factors and consequences from the viewpoint of users of the Catalan national health system (Spain)....

Additional file 1: of Retention of medical doctors at the district level: a qualitative study of experiences from Tanzania

Nathanael Sirili, , , , Amani Anaeli, , Isabel Goicolea &
Interview guide for the interviews with District Health Managers (DHSS). This semi-structured interview guide (set of questions) was used for carrying the key informant interviews with the District Health Managers from the three districts. (DOC 34 kb)

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