4,580 Works

Grafting of aspirin on to gelatin for anti-inflammatory effect in scaffold development

Mihir Ravindra Moghe
In recent times, there is an increasing interest in the field of tissue engineering for biochemical or biomedical use. A core component of tissue engineering is the scaffolds used for controlling cell growth. These scaffolds are made of a plethora of materials, each with their own distinct properties, which can be further modified by the addition of secondary substances like drug molecules.Gelatin is a commonly used biomaterial for the formation of gel scaffolds. However, due...
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Convex optimization based planning and control methods for space-robotic systems

Gaurav Misra
Space-robotic systems are arguably the most promising technologies available currently for on-orbit satellite operations including docking, berthing, and repair, which have been demonstrated in typically manned and semi-autonomous missions. Another important application of space-robotic systems is space debris mitigation. Space debris are uncooperative space objects (i.e. without any internal actuation) including defunct satellites and spent rocket stages, all of which pose tremendous risk to current operational space assets. Autonomous robotic capture, control, and stabilization of...
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Understanding and managing risk of norovirus contamination on frozen berries from farm to fork

Robyn C. Miranda
Norovirus is the leading cause of acute gastroenteritis worldwide. Consumption of frozen berries have been identified as a risk factor for norovirus illness. This dissertation studies four scenarios that affect the risk of norovirus on frozen berries: the effect of freezing and frozen storage on the survival of bacteriophage MS2 (a norovirus surrogate) on frozen strawberries and raspberries; thermal inactivation kinetics of MS2 on frozen strawberry and raspberry purées in a water bath; efficacy of...
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Evaluating the effects of training load, biomarkers, sleep, and mood status on performance outcomes in female collegiate soccer athletes

Bridget A. McFadden
Soccer is a physically demanding sport requiring frequent bouts of high intensity activity coupled with high caloric expenditures and an average distance covered of 10 km. Collegiate soccer is further characterized by a short intense preseason, combined with a season of congested match fixtures, frequent travel, and academic requirements often with minimal recovery allotted. Therefore, methods designed to track recovery needs of the athletes and promote optimal performance are essential to a successful sports science...
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"Smart" polyelectrolyte nanomedicine for cystic fibrosis pneumonia

Jessica McDonald
Bacterial biofilms build up in the sputum of cystic fibrosis patients, causing chronic respiratory infections and eventual lung failure. This mucus layer contains several bacterial species including gram-negative Pseudomonas aeruginosa and gram-positive Staphylococcus aureus, which are hard to eliminate, as multi-drug resistant strains, such as MRSA, develop. Three significant antimicrobial drugs known to fight cystic fibrosis lung infections include polymyxin B (PB), tobramycin (TB), and cathelicidin LL-37. Encapsulating such antimicrobials in self-assembling, amphiphilic polyelectrolyte surfactants...
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Screening and management of adolescent depression in a large pediatric care network

Alyssa E. McCarthy
There is low access to adolescent depression care due to lack of identification, a shortage of mental health professionals, and personal and logistical barriers to seeking treatment. Primary care has therefore been promoted as a setting to identify and manage this prevalent and impairing condition.Data for this study came from electronic health record (EHR) extraction in a large pediatric care network with an organizational recommendation to screen for depression at age 16 well visits using...
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Rooms of invention: the prison poems of Sir Thomas Wyatt and Henry Howard, Earl of Surrey

Regina Ann Masiello
This dissertation argues that Sir Thomas Wyatt’s and Henry Howard, the Earl of Surrey’s prison poems can be understood in a myriad of ways: as articulations of deep and abiding political and personal anxieties; as formal (sometimes mimetic) expressions of the suffocating limitations of incarceration; or as self-conscious continuations of prison poems (and of the profound prison tradition) which came before. But most importantly, these poems must be read as political performances, bids at self-representation,...
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Revealing the unseen river, a rivercentric landscape exploration

Sanja Martic
The thesis proposes a better understanding of what it takes to design a riverine landscape from a rivercentric perspective. The Raritan River in the City of New Brunswick is explored through this lens with two design goals in mind: improving the visibility of the Raritan riverscape in the city, and simultaneously, utilizing the Raritan riverscape to create green open space connectivity on a local as well as a regional scale.This thesis looks to answer whether...
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The effects of α-GPC supplementation on growth hormone, fat loss, and body composition in overweight adults

William G. Maldonado
In the United States, there is an increasing prevalence of obesity that is associated with health risks, and, as such, the need for effective weight loss methods is becoming increasingly more important. In the elderly, α-GPC has been shown to significantly increase growth hormone (GH) concentrations, a major stimulator of lipolysis and protein synthesis. However, very little work has been done in younger individuals. PURPOSE: to investigate if α-GPC, an acetylcholine precursor, could confer additional...
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Developing E. coli-E. coli co-cultures to overcome barriers of heterologous tryptamine biosynthesis

Xiaonan Wang, Lizelle Policarpio, Dhara Prajapati, Zhenghong Li & Haoran Zhang
Tryptamine is an alkaloid compound with demonstrated bioactivities and is also a precursor molecule to many important hormones and neurotransmitters. The high efficiency biosynthesis of tryptamine from inexpensive and renewable carbon substrates is of great research and application significance. In the present study, a tryptamine biosynthesis pathway was established in a metabolically engineered E. coli-E. coli co-culture. The upstream and downstream strains of the co-culture were dedicated to tryptophan provision and conversion totryptamine, respectively. The...
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Identification of a chlorodibenzo-p-dioxin dechlorinating Dehalococcoides mccartyi by stable isotope probing

Hang T. Dam, Weimin Sun, Lora R. McGuinness, Weimin Sun & Max M. Häggblom
Polychlorinated dibenzo-p-dioxins (PCDDs) are released into the environment from a variety of both anthropogenic and natural sources. While highly chlorinated dibenzo-p-dioxins are persistent under oxic conditions, in anoxic environments these organohalogens can be reductively dechlorinated to less chlorinated compounds that are then more amenable to subsequent aerobic degradation. Identifying the microorganisms responsible for dechlorination is an important step in developing bioremediation approaches. In this study, we demonstrated the use of a DNA-stable isotope probing (SIP)...
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Arctic tundra soil bacterial communities active at subzero temperatures detected by stable isotope probing

Preshita S. Gadkari, Lora R. McGuinness, Minna K. Männistö, Lee J. Kerkhof & Max M. Häggblom
Arctic soils store vast amounts of carbon and are subject to intense climate change. While effects of thaw on the composition and activities of Arctic tundra microorganisms has been examined extensively, little is known about the consequences of temperature fluctuations within the subzero range in seasonally frozen or permafrost soils. This study identified tundra soil bacteria active at subzero temperatures using stable isotope probing (SIP). Soils from Kilpisjärvi, Finland were amended with 13C-cellobiose and incubated...
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Visualizing particle and pore arrangements in dry-pressed spray-dried alumina (Al2O3) as a function of processing parameters

Ian Patrick Maher
Variability in green bulk density in ceramic green bodies has been a continuing issue in the ceramic processing industry. Dry-pressing of ceramic powders is a widely used process due to its low cost, high production rates, and shape forming abilities. Spray-drying is the most widely used granulation technique for large production of dry-pressed ceramics. One mechanism that can cause variation in green bulk density is inadequate cohesion of the spray-dried granules during compaction. Organic binders...
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Labor market institutions and political engagement in the U.S.

Gregory Lyon
How do lower-income individuals become involved in politics? The answer to this question—one that is at the heart of the current study and invokes core questions of political participation and inequality—is that labor unions are an important part of the answer. This study expands on the role of labor unions as foundational institutions upon which lower-income individuals are drawn into politics, have opportunities to engage with their political system, and level the participatory playing field...
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Luminescence in metal-organic frameworks: mechanisms and applications as phosphors and sensors

William P. Lustig
Luminescent metal‐organic frameworks (LMOFs) are a class of supramolecular material composed of metal ions connected by organic ligands to form crystalline frameworks that emit light when excited. In these organic‐inorganic frameworks, single metal ions or metal ion clusters serve as ‘nodes’, with rigid multidentate ligand molecules linking these nodes into an ordered three‐dimensional lattice. Luminescence can arise from the metal nodes, organic ligands, or interactions between these components. Because the properties of an LMOF depend...
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Reconfiguring space-time constraints: an exploratory research of the entanglement of urban space and digital media technologies

Weixu Lu
This dissertation research addresses the question, how do city residents make sense of urban spaces and places? Additionally, with the abundance of digital information about local places, what is the role of digital technology in reconfiguring these socio-spatial practices? In-depth interviews and contextual field inquiry data using mobile eye-tracking with participants recruited from a large American city was used to investigate the socio-spatial practices of contemporary city residents'. Findings from this research reveals the inseparability...
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Applications of biotechnology for crop enhancement in disease resistance and nutrition

Yee Chen Low
Developments in plant biotechnology are providing solutions for addressing the problems and challenges of sustainable agriculture and providing healthy food. Engineering disease resistant and nutritionally improved agricultural crops is integral to the application of plant biotechnology. In this thesis study, our core interests are on (i), studying and manipulating the economically important plant disease Fusarium head blight (FHB) by generating CRISPR-edited Arabidopsis resistant mutant plants; and (ii), producing nutritionally enhanced tomato plants with a two-in-one...
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Enabling high-quality mobile immersive computing through edge support

Luyang Liu
Emerging Mobile Immersive Computing applications, such as Virtual Reality (VR), Augmented Reality (AR), and Mixed Reality (MR), are changing the way human beings interact with the world. Such systems promise to provide unprecedented immersive experiences in the fields of video gaming, education, and healthcare. However, several key processes, such as rendering and object detection, are highly computational intensive, which make them extremely hard to run on mobile devices. Offloading these bottleneck processes to the edge...
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Towards smart and secure IoT with pervasive sensing

Jian Liu
With the advancement of mobile sensing and pervasive computing, extensive research is being carried out in various application domains of Internet of Things (IoT), such as smart home, smart healthcare, connected vehicles, and their security issues. My research work explores the power of pervasive sensing technologies to benefit people's daily lives and make impacts on society advancement, especially in the emerging areas of smart healthcare, IoT security and IoT embedded system communications. In this dissertation,...
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Developing a nanopore sequencing data processing pipeline for structure variation identification

Timothy Lin
Many genomic sequencing technologies have been developed since the Human Genome Project. These next-generation sequencing (NGS) technologies from various companies reshaped the genomics field and have improved rapidly. However, NGS has limitations for certain applications due to its short read length. The third generation of sequencing technology uses single molecule real-time sequencer that can generate long reads. Recently Oxford Nanopore entered the market with the release of its MinION sequencer. Oxford Nanopore's unique third generation...
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Defeating speaker recognition systems using adversarial examples

Zhuohang Li
Voice-user interface (VUI) has exploded in popularity due to the recent advances in automatic speech recognition (ASR). Such an interface has been integrated into various platforms, such as mobile phones, smart appliances and stand-alone voice assistants, and provides a convenient way for people to interact with them. Moreover, with such a convenient VUI, voice speaker recognition system that could be seamlessly integrated to facilitate security-related applications or personalized services has gained considerable attention recently. However,...
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Anisotropic seismic properties beneath the Northern Appalachians: a guide for past and present deformations within the upper mantle

Yiran Li
Seismic anisotropy, the directional dependence of seismic velocity, is a proxy for deformation at the depth. Within the Earth’s upper mantle, anisotropic seismic observations likely reflect the strain-induced realignment of olivine crystals, which is the major component of upper mantle peridotite. The pervasive mineralogical fabrics form by both the present-day convection of asthenosphere, and the past deformations imprinted in the lithosphere by plate motion and orogenesis. The topography and the surface geology of the Northern...
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Defending visual adversarial examples with smoothout regularization

Weitian Li
In the past decades with unexpected and rapid development of computer vision, tremendous computer vision applications like face recognition, image recognition, object detection and so on. They present their powerful abilities to made life so convenient for humans. In the trend of computer vision, deep neural networks (DNNs) occupies a very essential role. Because relative applications are deploying in many critical fields such as autonomous car, authentication and so on. However, there exist many adversarial...
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Nick Virgilio haiku archive, box 09 folder 06

Virgilio, Nicholas A. (Nicholas Anthony)
The Nicholas Virgilio Haiku Archive is primarily composed of sheets of typed haiku poems, several poems to a page, only a few ever published; some correspondence, mostly related to publishing or speaking engagements; and a small amount of personal correspondence. Virgilio lived in Camden, New Jersey and is a renowned haikuist.
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Essays on health outcomes, economic wellbeing and mismeasured discrete health variables

Ning Li
This thesis studies the labor supply effects of health shocks for aging Americans. To address the mismeasured binary health variables used in the labor supply equation, this thesis develops a new theoretical approach to the non-classical measurement error. In addition to Chapter 1 which provides an overview of the thesis, there are three primary chapters explaining the theoretical development and the empirical studies.Chapter 2 theoretically addresses the estimation bias due to the misclassification of a...
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Registration Year

  • 2019
    4,580

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    3,925
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    323
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    270
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    34
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    20
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    8