13 Works

Nanotoxicity from Ionization Enthalpy

Egon Willighagen
Data from the "Using nano-QSAR to predict the cytotoxicity of metal oxide nanoparticles" paper in Nature Nanotechnology (doi:10.1038/nnano.2011.10) showing the main finding.

A genetic switch

Egon Willighagen
Reaction acting as genetic switch, catalyzed by hydrogen peroxide. Published in Govan, J. M., McIver, A. L., Riggsbee, C. & Deiters, A. Hydrogen peroxide induced activation of gene expression in mammalian cells using boronate estrone derivatives. Angewandte Chemie International Edition n/a (2012). URL http://dx.doi.org/10.1002/anie.201203222.

A genetic switch

Egon Willighagen
Reaction acting as genetic switch, catalyzed by hydrogen peroxide. Published in Govan, J. M., McIver, A. L., Riggsbee, C. & Deiters, A. Hydrogen peroxide induced activation of gene expression in mammalian cells using boronate estrone derivatives. Angewandte Chemie International Edition n/a (2012). URL http://dx.doi.org/10.1002/anie.201203222.

Nanotoxicity from Ionization Enthalpy

Egon Willighagen
Data from the "Using nano-QSAR to predict the cytotoxicity of metal oxide nanoparticles" paper in Nature Nanotechnology (doi:10.1038/nnano.2011.10) showing the main finding.

Identification and development of adverse outcome pathways

Marvin Martens, Egon Willighagen & Chris Evelo
The vision of EU-ToxRisk is to allow the paradigm shift of toxicity assessment, from in vivo testing towards reliable, animal-free hazard and risk assessment of chemicals. EUToxRisk developed various case studies on five main topics of toxicity: liver, lung, kidney, neuronal system and developmental and reproductive toxicity. The purpose of these case studies is to provide a proof of concept for the use of AOPs by integrating new developments in in vitro and in silico...

Identification and development of adverse outcome pathways

Marvin Martens, Egon Willighagen & Chris Evelo
The vision of EU-ToxRisk is to allow the paradigm shift of toxicity assessment, from in vivo testing towards reliable, animal-free hazard and risk assessment of chemicals. EUToxRisk developed various case studies on five main topics of toxicity: liver, lung, kidney, neuronal system and developmental and reproductive toxicity. The purpose of these case studies is to provide a proof of concept for the use of AOPs by integrating new developments in in vitro and in silico...

ByteMAL Poster - 23-6-2017

Marvin Martens, Egon Willighagen & Chris Evelo
This poster was presented at byteMAL (Bioinformatics for Young inTernational researchers Expo: Maastricht-Aachen-Liège) 2017, in Maastricht on 23rd of June, 2017.

The future of regulatory toxicity assessment: Adverse Outcome Pathways

Marvin Martens, Egon Willighagen & Chris Evelo
This poster was presented at byteMAL (Bioinformatics for Young inTernational researchers Expo: Maastricht-Aachen-Liège) 2017, in Maastricht on 23rd of June, 2017.

The future of regulatory toxicity assessment: Adverse Outcome Pathways

Marvin Martens, Egon Willighagen & Chris Evelo
This poster was presented at byteMAL (Bioinformatics for Young inTernational researchers Expo: Maastricht-Aachen-Liège) 2017, in Maastricht on 23rd of June, 2017.

Pathway curation: from isolated pathway knowledge to search-click-and-grow.

Andra Waagmeester, Egon Willighagen & Martina Kutmon
We here present an approach to address the problem of aggregating all knowledge supporting or contradicting biological pathways. With the increasing accuracy and high-throughput aspects of nowadays biological experimental research, the amount of data for known pathways is exploding. However, it is hard to match past knowledge on pathways against these new data and insights. Pathways, like signalling, metabolic, and transcription pathways, are abstractions of biological interactions. They provide a way to present large quantities...

Pathway curation: from isolated pathway knowledge to search-click-and-grow.

Andra Waagmeester, Egon Willighagen & Martina Kutmon
We here present an approach to address the problem of aggregating all knowledge supporting or contradicting biological pathways. With the increasing accuracy and high-throughput aspects of nowadays biological experimental research, the amount of data for known pathways is exploding. However, it is hard to match past knowledge on pathways against these new data and insights. Pathways, like signalling, metabolic, and transcription pathways, are abstractions of biological interactions. They provide a way to present large quantities...

POSTER<< Chemistry Identifier Mapping to Pathway Databases using Ontologies: Expanding metabolomics analysis in WikiPathways with ChEBI >>POSTER

De Sl, Egon Willighagen & Https://Orcid.Org/0000-0002-5301-3142
Poster presented
at BioSB 2018 (https://www.aanmelder.nl/biosb2018#.WwrDKKSFOM8 )
and
at the 11th International Conference on Chemical Structures, May 27-31 2018, Noordwijkerhout, The Netherlands (http://www.int-conf-chem-structures.org/registration.html).

POSTER<< Chemistry Identifier Mapping to Pathway Databases using Ontologies: Expanding metabolomics analysis in WikiPathways with ChEBI >>POSTER

De Sl, Egon Willighagen & Https://Orcid.Org/0000-0002-5301-3142
Poster presented
at BioSB 2018 (https://www.aanmelder.nl/biosb2018#.WwrDKKSFOM8 )
and
at the 11th International Conference on Chemical Structures, May 27-31 2018, Noordwijkerhout, The Netherlands (http://www.int-conf-chem-structures.org/registration.html).

Resource Types

  • Image
    13

Publication Year

  • 2018
    4
  • 2017
    3
  • 2012
    4
  • 2011
    2

Registration Year

  • 2018
    4
  • 2017
    3
  • 2016
    3
  • 2012
    3

Data Centers

  • figshare Academic Research System
    13