Additional file 1: Supplemental figures 1-28.

Additional file 4. Uncropped images for the blots in Figure S3 and Figure S28.

Additional file 2: Fig. S1. Typical grapevine trunk disease (GTD) symptoms in grapevines collected in this study. A The overall condition of symptomatic grapevines with yellow spots or tiger stripes on the leaves of multiple branches. B Foliar symptoms that initially appeared as chlorotic spots and subsequently coalesced and finally became necrotic. C Internal symptoms of the same vine with foliar symptoms showing dark brown necrosis. Fig. S2. Species accumulation curves for fungal communities based...

Additional file 1: Fig. S1. The animal experimental protocol. DSS, dextran sulfate sodium; GC-K, ginsenoside compound K. Fig. S2. The frequency of Foxp3 + Treg cells among the CD4 + T cells (CD3 + CD4 + CD25 + cells) in spleen(A) and blood(B) of mice detected by flow cytometry; The frequency of IL-17a + Th17 cells among the CD4 + T cells (CD3 + CD4 + cells) in spleen(C) and blood(D) of mice detected by...

Additional file 3: Fig. S3. Combined treatment decreases oxidative phosphorylation and increases glycolytic reserve in highly aggressive TNBC cells. a. Oxygen Consumption Rate (OCR) measurements in MCF-10A and MDA-MB-231 cells treated with DXR alone or in combination with STS, using Seahorse Analyzer. Combination treatment selectively reduces basal respiration (corresponding to basal OCR), maximal respiration (corresponding to FCCP response) and spare respiratory capacity (the difference between maximal respiration and basal respiration). b. Extracellular Acidification Rate (ECAR)...

Additional file 3: Supplementarydata 1. Original pictures used to prepare the Figure 6

Additional file 4: Fig. S4. The co-expression network of the PgHDZ gene transcripts expressed in four-year-old plant roots of 42 cultivars. (a) The co-expression network of the PgHDZ gene transcripts constructed at p ≤ 5.0E-02. (b) Ten clusters of the co-expression network. (c and d) The co-expression network formation tendency of the PgHDZ gene transcripts presented by the number of nodes (c) and the number of edges (d). (e and f) Statistics of the co-expression...

Additional file 1: Fig. S1. The conserved motifs of the genes in the PgHDZ gene family determined by MEME. The height of each letter represents the conservation level of the nucleotide across the PgHDZ genes.

Additional file 3: Figure S3 Restricted cubic spline plots of the association between the TATS and the risk of NAFLD. a Analyses were adjusted for age, BMI, waist, Alt, Ast, HDL-C, HbA1c, protein intake, sex, education level, DM, and alcohol user. b Analyses were adjusted for age, BUN, smoker, waist, Alt, HbA1C, sex, TC, alcohol user, HDL-C, education level, and dietary Vitamin C intake. Solid and dashed lines represent the log-transformed odds ratios and the...

Additional file 2. Supplementary Figures.

Additional file 2: Figure S2 LASSO regression model screening potential predictors of NAFLD. a LASSO regression model cross-validation plot. Draw a vertical line at the optimum with the minimum criterion and 1se of the minimum criterion. When λ = 0.020, we get 13 variables, including TATS, for further analysis. b Coefficient profile plot of predictors. Finally, 13 variables including TSAT, were selected at the optimal lambda. LASSO, least absolute shrinkage and selection operator.

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3D RI reconstruction of MCF-7 cells.

Supplemental material, sj-pptx-1-cpa-10.1177_07067437231154993 for A Meta-Research of Randomized Controlled Trials in the Field of Mental Health: Comparing Pharmacological to Non-Pharmacological Interventions from 1955 to 2020 by Sheng Chen, PhD, Alina Lee, MSc, and Wei Wang, PhD in The Canadian Journal of Psychiatry

Blackleg, caused by the fungus Leptosphaeria maculans, is an important disease of canola. Both ascospores and pycnidiospores of the fungus can infect intact leaves under conditions of extended leaf wetness, with infection then progressing further into the stem. In western Canada, spring is typically cool and dry and additional factors may be involved for successful infection. This study was designed to assess the effect of wounding and wound age on cotyledon infection, to evaluate the...

Background. Far-field electrograms from superior vena cava (SVC) can be present in right superior pulmonary vein (RSPV) after pulmonary vein (PV) isolation. Objectives. To analyze the characteristics of far-field SVC potentials in RSPV after PV isolation and the local anatomy difference between patients with and without the potentials. Methods. Patients undergoing PV isolation were retrospectively reviewed, contrast-enhanced computed tomography (CT) was performed before procedure for observing the anatomical relationship between RSPV and SVC. The prevalence...

We previously described using a “Y” incision and rectangular patch to enlarge the aortic annulus by 2-3 valve sizes for aortic valve replacement (AVR) with bioprosthesis (1) or mechanical valve (2) in patients with trileaflet aortic valve (TAV). As we are becoming more experienced, we are able to enlarge the aortic annulus by 4 valve sizes routinely in either TAV or bicuspid aortic valve (BAV). In this video we used a case of TAV to...

Objectives: Schizophrenia is a devastating mental disease. Various microRNAs were proven to be associated with schizophrenia. Altered microRNA-144-3p (miR-144-3p) levels were found in various neurological and psychotic disorders. Beta2-subunit of Na(+)/K(+)-ATPase (ATP1B2) regulates neuronal migration and cell growth during brain development through the PI3K/Akt/mTOR pathway. The present study explored the associations of miR-144-3p and ATP1B2 with schizophrenia and their mutual interaction. Methods: A schizophrenic animal model employing repeated MK-801 administration was established and 293 T...

Additional file 1. Preparation for iTRAQ quantitative proteomics study.

Additional file 4. High correlation between the two technical replicates. The scatterplot of two technical replicates treated with 20/80/160 Gy heavy ion irradiation.

Additional file 5. String analysis of 113 overlapped differential proteins in our dataset.

Astragalus membranaceus is a traditional Chinese medicine and has been widely used in treating cardiovascular diseases (CVDs), such as asthma, edema, and chest tightness. Astragaloside IV (AS-IV), one of the major active components extracted from Astragalus membranaceus, has a series of pharmacological effects, including inhibiting inflammation, regulating energy metabolism, reducing oxidative stress and apoptosis. However, the effect of AS-IV on myocardial infarction (MI) and the underlying molecular mechanism remains unclear. The purpose of our study...

Video showing sunrise seagrass wasting disease survey via snorkeling on San Juan Island, Washington.

Video showing sunrise seagrass wasting disease survey via snorkeling on San Juan Island, Washington.

Shot-to-shot pulse evolution during the mode-locking transition of a Ti:sapphire oscillator. The upper panel shows the result obtained by detecting the unstretched pulses, and the lower one shows the TS-DFT result, which adopts the same data as those used in Fig. 1(b) of the main text. Time synchronization of these two channels has been implemented to make sure the pulse energy reaches the maximum at the same time in both cases (see Fig. 2(c) of...