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Supplementary Media for Self-Supervised Deep Learning Two-Photon Microscopy

Animation of phase distribution evolutions of the x-polarized component along the x-axis and that of the y-polarized component along the y-axis in radially polarized two dimensional STOV.

The dynamic evolution of rays in 3D geodesic lens.

The dynamic evolution of waves in 2D MFE lens.

Mouse photoreceptor mosaic imaged with AO-SLO.

Animation of the spatial polarization evolution of the focused wavepacket corresponding to the preconditioned radially polarized incident wavepacket.

Animation of phase distribution evolutions of the x-polarized component along the x-axis and that of the y-polarized component along the y-axis in radially polarized two dimensional STOV.

Additional file 6. The original blots.

laser irradiation of the CLG-SiO2 sample with wavelength of 532 nm and laser power of 60 mW at normal pressure

macroscopic laser pulling of the CLG-SiO2 sample with wavelength of 488 nm and laser power of 68 mW at the air pressure of 5 Pa

Endoscopic ultrasound (EUS)-guided natural orifice transluminal gallbladder polypectomy provides a minimally invasive alternative to cholecystectomy. The study aimed to investigate the feasibility and safety of protocol for gallbladder endoscopic mucosal resection (gEMR) under EUS guidance using a porcine model. Fifteen Bama mini pigs were randomly divided into the control (CG, n = 3) and experimental (EG, n = 12) groups. EUS-guided fine needle aspiration was performed in the CG and used to establish a gallbladder...

Additional file 1: Figure S1. Full-length blots/gels of ABCA1, MMP9, AQP4, CYP46, and beta-actin are presented. Figure S2. Full-length blots/gels of phospho-PI3K, PI3K, AKT, phospho-AKT, eNOS, phospho-eNOS and beta-actin are presented. Figure S3. Full-length blots/gels of ABCA1 and beta-actin are presented. Figure S4. Full-length blots/gels of MMP9, AQP4, CYP46 and β-actin are presented. Figure S5. Full-length blots/gels of phospho-PI3K, PI3K, AKT, phospho-AKT, eNOS, phospho-eNOS and β-actin are presented.

Additional file 1: Supplementary Fig. 1. A circular genomic map displays the distribution of all KRAB-ZFP genes across the human genome. The width of each pink bar positively correlates to the number of KRAB-ZFP genes in a cluster.

The movement of a water surface and splashed drops after a water drip dropping on the surface.

Additional file 5 Supplementary Fig. 5. Screening efficient sgRNAs for knocking out KRAB-Zfp cluster(s) by CRISPR-Cas9. (A) The sequences and detailed information of the 11 linker-targeting sgRNAs constructed in the reporter plasmid in Fig. 4A. There are two “NGG” sites within the linker regions and they were used as PAM sites for the two sets of sgRNAs. The nucleotides identical across the whole set of sgRNA targets are labeled in black and the variable nucleotides...

Additional file 8 Supplementary Fig. 8. Analyses of KRAB-Zfp related Satellite DNA cluster identified in the Kauzlaric’s paper [32]. (A) Comparison of the cluster distribution of our work and the Kauzlaric’s paper. The clusters defined by both studies are pointed with red arrows; the clusters only defined by our work are pointed with blue arrows; and the clusters only defined by the Kauzlaric’s paper are pointed with green arrows, mainly including the KRAB-Zfp related Satellite...

Additional file 3. The basics of machine operation, image acquisition and optimization and saving an image

Additional file 4. Ultrasound-guided vascular access procedures

Additional file 4. Ultrasound-guided vascular access procedures

Additional file 5. Ultrasound-guided non-vascular access and advanced procedures

Additional file 6. Focused echocardiographic examination

Additional file 7. Hemodynamic assessment of a critically ill patient using point-of-care ultrasound

Additional file 6. KEGG and GO enrichment analysis of 452 differential proteins in our dataset.

Additional file 3. The Gaussian fitting curve of log2 ratio of the intensities of two replicates of 20/0 (A), 80/0 (B) and 160/0 (C). The red and blue curves represent the experimental and Gaussian fitting curve, respectively.