The beam profile recorded for 10 s demonstrates the absence of transverse mode instability.

Animation of FIg. 3

Additional file 4 Supplementary Fig. 4. Sequence conservation analyses of various KRAB-Zfp clusters. The amino acid sequences (top) and the corresponding nucleic acid sequences (bottom) according to the linker and nearby regions are shown in the pale purple box. The related sequences are extracted from all the KRAB-Zfps arranged in the 50 clusters across the mouse genome (a), or the indicated clusters on chromosome 2 (Clusters 1, 2, 3) (b), and on chromosome 4 (Clusters...

Supplementary Material 3

Additional file 1: Supp Fig. 1. A clinico-diagnositicflowchart of the antenatal management in different cases. SuppFig. 2. The differential expression mRNAswere verified by RT-PCR in TOF patients and Controls.

Additional file 6 Supplementary Fig. 6. Specificity tests of sgRNAs in qPCR assays. qPCR results for detecting the intergenetic regions between non-target KRAB-Zfps using the genomic DNA templates extracted from the cells expressing the indicated sgRNA before and after gene editing (−Dox and + Dox). The set of data are correlated to Fig. 5B.

20 reconstructed frames from the single-shot measurement with each one corresponding to the duration of 1 millisecond for the heart motions of zebrafish.

Quantitative simulation comparison.

Quantitative simulation comparison about the robustness of proposed method.

Endoscopic ultrasound (EUS)-guided natural orifice transluminal gallbladder polypectomy provides a minimally invasive alternative to cholecystectomy. The study aimed to investigate the feasibility and safety of protocol for gallbladder endoscopic mucosal resection (gEMR) under EUS guidance using a porcine model. Fifteen Bama mini pigs were randomly divided into the control (CG, n = 3) and experimental (EG, n = 12) groups. EUS-guided fine needle aspiration was performed in the CG and used to establish a gallbladder...

We discovered that vitiligo was associated with sexual dysfunction in clinical diagnosis and treatment; however, no further analysis had been performed due to a lack of data. This study aimed to clarify the relationship between vitiligo and sexual dysfunction. We searched six databases (PubMed, Embase, Cochrane, China National Knowledge Infrastructure, China Science and Technology Journal, and Wanfang Data Knowledge Service Platform) for nearly 40 years. According to the search strategy, 91 relevant studies were retrieved,...

A well-developed root system plays a positive role in wheat yield. Here, we identified quantitative trait loci (QTL) for total root length (TRL), root average diameter (RD) and number of root tips (RTN) based on the previously developed genetic map of a recombinant inbred line (RIL) population in bread wheat and phenotype data from two individual trials. A stable and major QTL, Qtrl-AS-5A for TRL was detected explaining 17.19 to 17.78% of the phenotypic variation....

The beam profile recorded for 10 s demonstrates the absence of transverse mode instability.

Additional file 1: Figure S1. Comparison of indicators in patients with negative bacterial culture beforeand after appropriate antibiotic therapy.

Additional file 2: Figure S2. The daily alteration of the nCD64 index, PCT, and temperature in infectedpatients.

20 reconstructed frames from the single-shot measurement with each one corresponding to the duration of 1 millisecond for the heart motions of zebrafish.

Reconstruction results with 20 frames of zebrafish heart from a snapshot measurement.

Reconstruction results with 20 frames of zebrafish heart from a snapshot measurement.

Four groups of experimental data comparison about the robustness of proposed method.

Quantitative simulation comparison about the robustness of proposed method.

Video of non-DoT system simulation of scene 2 in 45 degree.

Video of non-DoT system simulation of scene 2 in 45 degree.

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Supplementary Material 3

Additional file 1: Supplementary Fig. 1. A circular genomic map displays the distribution of all KRAB-ZFP genes across the human genome. The width of each pink bar positively correlates to the number of KRAB-ZFP genes in a cluster.