Additional file 3. The MS/MS spectra of CAP and its products determined by HPLC-QTOF-MS.

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Additional file 1. Preparation for iTRAQ quantitative proteomics study.

Supplementary Material 3

Additional file 2.

Supplementary Media for Self-Supervised Deep Learning Two-Photon Microscopy

Supplementary Media for Self-Supervised Deep Learning Two-Photon Microscopy

Supplementary Media for Self-Supervised Deep Learning Two-Photon Microscopy

Additional file 1: Figure S1. Full-length blots/gels of ABCA1, MMP9, AQP4, CYP46, and beta-actin are presented. Figure S2. Full-length blots/gels of phospho-PI3K, PI3K, AKT, phospho-AKT, eNOS, phospho-eNOS and beta-actin are presented. Figure S3. Full-length blots/gels of ABCA1 and beta-actin are presented. Figure S4. Full-length blots/gels of MMP9, AQP4, CYP46 and β-actin are presented. Figure S5. Full-length blots/gels of phospho-PI3K, PI3K, AKT, phospho-AKT, eNOS, phospho-eNOS and β-actin are presented.

Additional file 1: Figure S1. Female RAGE deficiency improved glucose and insulin tolerance in normal diet mice. (A) Glucose tolerance tests (GTT) and Area under the curve (AUC) in each group. n = 6 per group. *p < 0.05 vs. female RAGE−/−-HFD-F mice; #p < 0.05 vs. female RAGE−/−-ND-F mice. (B) Insulin tolerance tests (ITT) and AUC in each group. n = 6 per group. *p < 0.05 vs. female RAGE−/−-HFD-F mice; #p < 0.05...

Additional file 3. The Gaussian fitting curve of log2 ratio of the intensities of two replicates of 20/0 (A), 80/0 (B) and 160/0 (C). The red and blue curves represent the experimental and Gaussian fitting curve, respectively.

Additional file 2. Expression profiles of circNFAT5 in different blood compartments from samples of 3 volunteers.

Capture performance of annular GPOVs

Supplementary Material 1

Multi-motor configuration of multi-DOF (degree of freedom) optical system is a major source of redundant structure, putting a limitation on the simple and miniaturized design. Thus, a novel two-DOF ultrasonic motor (USM) is proposed to provide a feasible method of application in the lens autofocus of the optical system. The proposed USM operates by one longitudinal mode and two orthogonal bending modes, which is inspired by the bionic motion principle of the earthworms. The frequency...

Endoscopic ultrasound (EUS)-guided natural orifice transluminal gallbladder polypectomy provides a minimally invasive alternative to cholecystectomy. The study aimed to investigate the feasibility and safety of protocol for gallbladder endoscopic mucosal resection (gEMR) under EUS guidance using a porcine model. Fifteen Bama mini pigs were randomly divided into the control (CG, n = 3) and experimental (EG, n = 12) groups. EUS-guided fine needle aspiration was performed in the CG and used to establish a gallbladder...

Supplementary Media for Self-Supervised Deep Learning Two-Photon Microscopy

Capture performance of annular GPOVs

Animation of the quasi-CVT optimization process for an example Voronoi-Fresnel phase with 23 cells. The distance between the Voronoi-Fresnel phase and image sensor is set at 2 mm. The sensor pixels are 240 x 160, with a pixel pitch of 3.45 microns. The phase resolution is 1.15 microns, making a manufacturable 3x unsampling ratio compared with sensor resolution. To fully characterize the optimization, the process is run for 100 iterations, although the optimal result occurs...

Supplemental material, sj-pptx-1-tag-10.1177_17562848221124029 for ‘FLARE’ of tumor marker in advanced gastric cancer treated with first-line systemic therapy by Fangyuan Zhang, Menglan Zhai, Jinru Yang, Lei Zhao, Zhenyu Lin, Jing Wang, Tao Zhang and Dandan Yu in Therapeutic Advances in Gastroenterology

Astragalus membranaceus is a traditional Chinese medicine and has been widely used in treating cardiovascular diseases (CVDs), such as asthma, edema, and chest tightness. Astragaloside IV (AS-IV), one of the major active components extracted from Astragalus membranaceus, has a series of pharmacological effects, including inhibiting inflammation, regulating energy metabolism, reducing oxidative stress and apoptosis. However, the effect of AS-IV on myocardial infarction (MI) and the underlying molecular mechanism remains unclear. The purpose of our study...

A well-developed root system plays a positive role in wheat yield. Here, we identified quantitative trait loci (QTL) for total root length (TRL), root average diameter (RD) and number of root tips (RTN) based on the previously developed genetic map of a recombinant inbred line (RIL) population in bread wheat and phenotype data from two individual trials. A stable and major QTL, Qtrl-AS-5A for TRL was detected explaining 17.19 to 17.78% of the phenotypic variation....

If the barrier pitch is larger than the double-pixel pitch, then the green stripe falls behind the CCD’s movement.

Magnified imaging larger than the size of the microspheres

Visualization 3 shows smooth motion parallax with changing perspectives so that the transition among views is continuous, rather than an observable jump.