Additional file 2: Figure S1. GO enrichment of the differentially expressed proteins in different treatment comparisons of cadmium-treated Rhizoma Polygonati.

Additional file 2: Fig. S1. Typical grapevine trunk disease (GTD) symptoms in grapevines collected in this study. A The overall condition of symptomatic grapevines with yellow spots or tiger stripes on the leaves of multiple branches. B Foliar symptoms that initially appeared as chlorotic spots and subsequently coalesced and finally became necrotic. C Internal symptoms of the same vine with foliar symptoms showing dark brown necrosis. Fig. S2. Species accumulation curves for fungal communities based...

Additional file 1: Fig. S1. The animal experimental protocol. DSS, dextran sulfate sodium; GC-K, ginsenoside compound K. Fig. S2. The frequency of Foxp3 + Treg cells among the CD4 + T cells (CD3 + CD4 + CD25 + cells) in spleen(A) and blood(B) of mice detected by flow cytometry; The frequency of IL-17a + Th17 cells among the CD4 + T cells (CD3 + CD4 + cells) in spleen(C) and blood(D) of mice detected by...

Additional file 3: Fig. S3. Combined treatment decreases oxidative phosphorylation and increases glycolytic reserve in highly aggressive TNBC cells. a. Oxygen Consumption Rate (OCR) measurements in MCF-10A and MDA-MB-231 cells treated with DXR alone or in combination with STS, using Seahorse Analyzer. Combination treatment selectively reduces basal respiration (corresponding to basal OCR), maximal respiration (corresponding to FCCP response) and spare respiratory capacity (the difference between maximal respiration and basal respiration). b. Extracellular Acidification Rate (ECAR)...

The MYC and RAS oncogenes are sufficient for transformation of normal rodent cells. This cooperativity is at least in part based on suppression of RAS-induced cellular senescence by MYC and block of MYC-induced apoptosis by RAS – thereby canceling out two main barriers against tumor development. However, it remains unclear whether MYC and RAS cooperate in this way in human cells, where MYC and RAS are not sufficient for transformation. To address this question, we...

A well-developed root system plays a positive role in wheat yield. Here, we identified quantitative trait loci (QTL) for total root length (TRL), root average diameter (RD) and number of root tips (RTN) based on the previously developed genetic map of a recombinant inbred line (RIL) population in bread wheat and phenotype data from two individual trials. A stable and major QTL, Qtrl-AS-5A for TRL was detected explaining 17.19 to 17.78% of the phenotypic variation....

We previously described using a “Y” incision and rectangular patch to enlarge the aortic annulus by 2-3 valve sizes for aortic valve replacement (AVR) with bioprosthesis (1) or mechanical valve (2) in patients with trileaflet aortic valve (TAV). As we are becoming more experienced, we are able to enlarge the aortic annulus by 4 valve sizes routinely in either TAV or bicuspid aortic valve (BAV). In this video we used a case of TAV to...

Video showing sunrise seagrass wasting disease survey via snorkeling on San Juan Island, Washington.

Video showing sunrise seagrass wasting disease survey via snorkeling on San Juan Island, Washington.

A 360° dynamic holographic video

Under and over-focus images captured during FoV scan

Additional file 8 Supplementary Fig. 8. Analyses of KRAB-Zfp related Satellite DNA cluster identified in the Kauzlaric’s paper [32]. (A) Comparison of the cluster distribution of our work and the Kauzlaric’s paper. The clusters defined by both studies are pointed with red arrows; the clusters only defined by our work are pointed with blue arrows; and the clusters only defined by the Kauzlaric’s paper are pointed with green arrows, mainly including the KRAB-Zfp related Satellite...

We previously described using a “Y” incision and rectangular patch to enlarge the aortic annulus by 2-3 valve sizes for aortic valve replacement (AVR) with bioprosthesis (1) or mechanical valve (2) in patients with trileaflet aortic valve (TAV). As we are becoming more experienced, we are able to enlarge the aortic annulus by 4 valve sizes routinely in either TAV or bicuspid aortic valve (BAV). In this video we used a case of TAV to...

Article full text The above features represent the opinions of the authors. For a full list of declarations, including funding and author disclosure statements, please see the full text online (see “read the peer-reviewed publication” opposite). © The authors, CC-BY-NC 2022

Under and over-focus images via lateral scan

Images of random phase plate captured by two CMOS imaging chips during axial scan

Additional file 6 Supplementary Fig. 6. Specificity tests of sgRNAs in qPCR assays. qPCR results for detecting the intergenetic regions between non-target KRAB-Zfps using the genomic DNA templates extracted from the cells expressing the indicated sgRNA before and after gene editing (−Dox and + Dox). The set of data are correlated to Fig. 5B.

We discovered that vitiligo was associated with sexual dysfunction in clinical diagnosis and treatment; however, no further analysis had been performed due to a lack of data. This study aimed to clarify the relationship between vitiligo and sexual dysfunction. We searched six databases (PubMed, Embase, Cochrane, China National Knowledge Infrastructure, China Science and Technology Journal, and Wanfang Data Knowledge Service Platform) for nearly 40 years. According to the search strategy, 91 relevant studies were retrieved,...

The dynamic evolution of waves in 2D MFE lens.

The dynamic evolution of rays in 3D geodesic lens.

Under and over-focus images captured during FoV scan

Images of random phase plate captured by two CMOS imaging chips during axial scan

Under and over-focus images captured during FoV scan

Additional file 3: Figure S2. KEGG pathway enrichment of the differentially expressed proteins in different treatment comparisons of cadmium-treated Rhizoma Polygonati.

Additional file 1: Fig. S1. Starvation preferentially sensitizes different breast cancer subtypes versus near normal cells to chemotherapy. a. In vitro treatment overview: cells were glucose/serum starved (STS) for 48 h (blue bar), drugs were added during the last 24h (red bar). b. MTT survival assays after 48 h treatment with STS with or without addition of doxorubicin (DXR) in near normal MCF-10A cells and the indicated breast cancer cell lines. Data are presented as...