10,078 Works

Additional file 11: Figure S5. of Comparative genomics to explore phylogenetic relationship, cryptic sexual potential and host specificity of Rhynchosporium species on grasses

Daniel Penselin, Martin Münsterkötter, Susanne Kirsten, Marius Felder, Stefan Taudien, Matthias Platzer, Kevin Ashelford, Konrad Paskiewicz, Richard Harrison, David Hughes, Thomas Wolf, Ekaterina Shelest, Jenny Graap, Jan Hoffmann, Claudia Wenzel, Nadine Wöltje, Kevin King, Bruce Fitt, Ulrich Güldener, Anna Avrova & Wolfgang Knogge
Disease phenotype of DRcSP9 mutants. Primary leaves of barley cv. ‘Ingrid’ were inoculated with spores of wild-type isolate UK7 or of the mutants and photos were taken at indicated times post inoculation. C, mock inoculation. (PPTX 382 kb)

FOAMsalinity_2014-2015_anim.gif

Matthew Martin
Sea surface salinity animation from the FOAM system (http://www.metoffice.gov.uk/research/models/ocean-models)

Additional file 14: Figure S4. of Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance

Andre Vettore, Kalpana Ramnarayanan, Gregory Poore, Kevin Lim, Choon Ong, Kie Huang, Hui Leong, Fui Chong, Tony Lim, Weng Lim, Ioana Cutcutache, John Mcpherson, Yuka Suzuki, Shenli Zhang, Thakshayeni Skanthakumar, Weining Wang, Daniel Tan, Byoung Cho, Bin Teh, Steve Rozen, Patrick Tan & N. Iyer
Top ten significantly mutated pathways in oral tongue squamous cell carcinoma (OTSCC), as determined by examination of the Molecular Signatures Database (MSigDB) by Gene Set Enrichment Analysis (GSEA) software and comparisons with well-recognized cancer-related pathways. (PPT 137 kb)

MOESM2 of F4+ ETEC infection and oral immunization with F4 fimbriae elicits an IL-17-dominated immune response

Yu Luo, Ut Nguyen, Pedro Fe Rodriguez, Bert Devriendt & Eric Cox
Additional file 2. The distribution of mRNA in intestinal tissues of control pigs. The mRNA expression in intestinal tissues of control pigs was analyzed by qPCR. The mRNA expression was normalized to the reference genes and then to jejunum without Peyer’s patches. Data are presented as the mean ± SEM (n = 3 per group). JJ = jejunum without Peyer’s patches, JP = jejunum with Peyer’s patches, IL = ileum without Peyer’s patches, IP =...

MOESM3 of F4+ ETEC infection and oral immunization with F4 fimbriae elicits an IL-17-dominated immune response

Yu Luo, Ut Nguyen, Pedro Fe Rodriguez, Bert Devriendt & Eric Cox
Additional file 3. Oral immunization with F4 fimbriae induced F4-specific serum antibodies. The piglets were immunized with 1 mg F4 fimbriae on day 0 (D0), D1 and D2. Blood was drawn on D0 before immunization and D9 after immunization. The F4-specific antibody (Ab) titer was tested in serum using ELISA. Data are presented as the mean ± SEM (n = 5 per group).

Additional file 6: of Serotonin promotes exploitation in complex environments by accelerating decision-making

Shachar Iwanir, Adam Brown, Stanislav Nagy, Dana Najjar, Alexander Kazakov, Kyung Lee, Alon Zaslaver, Erel Levine & David Biron
Movie S2. Serotonin promotes exploitation of a single patch. A wild-type animal (left), a tph-1 mutant (middle), and a transgenic animal in which serotonergic neurons were genetically silenced (right) encounter a small patch of food (D = 700–800 μm). Only the wild-type animal was able to efficiently exploit this resource. (AVI 14921 kb)

MOESM4 of F4+ ETEC infection and oral immunization with F4 fimbriae elicits an IL-17-dominated immune response

Yu Luo, Ut Nguyen, Pedro Fe Rodriguez, Bert Devriendt & Eric Cox
Additional file 4. Effect of endotoxins on IL-17A secretion. PBMCs were stimulated with endotoxin-free F4 fimbriae (5 μg/mL), F4 fimbriae (5 μg/mL) in the presence or absence of polymyxin B (PMB, 25 μg/mL) or medium for 72 h. The IL-17A concentration in the cell-free supernatant was determined by ELISA. Data are presented as the mean ± SEM (n = 3).

Additional file 8: Figure S3. of Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance

Andre Vettore, Kalpana Ramnarayanan, Gregory Poore, Kevin Lim, Choon Ong, Kie Huang, Hui Leong, Fui Chong, Tony Lim, Weng Lim, Ioana Cutcutache, John Mcpherson, Yuka Suzuki, Shenli Zhang, Thakshayeni Skanthakumar, Weining Wang, Daniel Tan, Byoung Cho, Bin Teh, Steve Rozen, Patrick Tan & N. Iyer
Copy number variation plot summary of 18 oral tongue squamous cell carcinoma patients in the discovery set. The samples are sorted according to smokers and never-smokers as indicated. Regions of gains and losses are color coded as per the legend. (PPT 662 kb)

Additional file 12: Figure S7. of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

Hsiao-Rong Chen, David Sherr, Zhenjun Hu & Charles DeLisi
Titration curves of cell viability under treatment of Triprolidine. Viability of MCF10A, MCF7 and SUM 149 cells exposed to Triprolidine with concentrations ranging from 31.25 μM to 1000 μM after 24 h incubation. The relative viability was calculated as relative viability = (experimental absorbance - background absorbance)/ (absorbance of untreated controls - background absorbance of untreated controls) × 100 % (means ± SD, n = 3). (PPTX 55 kb)

Additional file 4: Figure S2. of Comparative genomics to explore phylogenetic relationship, cryptic sexual potential and host specificity of Rhynchosporium species on grasses

Daniel Penselin, Martin Münsterkötter, Susanne Kirsten, Marius Felder, Stefan Taudien, Matthias Platzer, Kevin Ashelford, Konrad Paskiewicz, Richard Harrison, David Hughes, Thomas Wolf, Ekaterina Shelest, Jenny Graap, Jan Hoffmann, Claudia Wenzel, Nadine Wöltje, Kevin King, Bruce Fitt, Ulrich Güldener, Anna Avrova & Wolfgang Knogge
CAZyme numbers in different fungal species. GH, glycosyl hydrolases; CE, carbohydrate esterases; PL, pectate lyases; GT, glycosyl transferases; CBM, carbohydrate binding motifs (modified after [50]). (PPTX 72 kb)

Additional file 7: Figure S2. of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

Hsiao-Rong Chen, David Sherr, Zhenjun Hu & Charles DeLisi
Titration curves of cell viability under treatment of Doxorubicin. Viability of MCF10A, MCF7 and SUM 149 cells exposed to Doxorubicin with concentrations ranging from 0.5 μM to 200 μM after 24 h incubation. The relative viability was calculated as relative viability = (experimental absorbance - background absorbance)/ (absorbance of untreated controls - background absorbance of untreated controls) × 100 % (means ± SD, n = 6). (PPTX 53 kb)

Additional file 8: Figure S2. of Identification of therapeutic targets applicable to clinical strategies in ovarian cancer

Marianne Kim, Natasha Caplen, Sirisha Chakka, Lidia Hernandez, Carrie House, Georgios Pongas, Elizabeth Jordan & Christina Annunziata
Dose-effect curves and output from median effect plot for MK1775, BI6727 and Oxozeaenol. (PPT 259Â kb)

Additional file 10: Figure S4. of Identification of therapeutic targets applicable to clinical strategies in ovarian cancer

Marianne Kim, Natasha Caplen, Sirisha Chakka, Lidia Hernandez, Carrie House, Georgios Pongas, Elizabeth Jordan & Christina Annunziata
Two-way ANOVA with Tukey post-hoc comparing effect of culture conditions and cisplatin or BI6727. (PPTX 112Â kb)

Additional file 9: of Serotonin promotes exploitation in complex environments by accelerating decision-making

Shachar Iwanir, Adam Brown, Stanislav Nagy, Dana Najjar, Alexander Kazakov, Kyung Lee, Alon Zaslaver, Erel Levine & David Biron
Movie S5. Physiological activity in NSM: the pharyngeal serotonergic neuron type. NSM is activated robustly and acutely upon encountering the edge of a newly discovered patch of food. (AVI 4421 kb)

Additional file 11: Figure S6. of A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

Hsiao-Rong Chen, David Sherr, Zhenjun Hu & Charles DeLisi
Titration curves of cell viability under treatment of Fluphenazine. Viability of MCF10A, MCF7 and SUM 149 cells exposed to Fluphenazine with concentrations ranging from 3.125 μM to 100 μM after 24 h incubation. The relative viability was calculated as relative viability = (experimental absorbance - background absorbance)/ (absorbance of untreated controls - background absorbance of untreated controls) × 100 % (means ± SD, n = 3). (PPTX 55 kb)

Additional file 1: of Serotonin promotes exploitation in complex environments by accelerating decision-making

Shachar Iwanir, Adam Brown, Stanislav Nagy, Dana Najjar, Alexander Kazakov, Kyung Lee, Alon Zaslaver, Erel Levine & David Biron
Movie S1. Serotonin accelerates the response to the edge of a bacterial lawn. An example of wild-type animals (left) and tph-1(mg280) mutants (right) encountering a large lawn of bacterial food. The wild-type response to the encounter was visibly more abrupt. The movie was sped up 50x as compared to real-time. (AVI 24296 kb)

Additional file 9: Figure S3. of Identification of therapeutic targets applicable to clinical strategies in ovarian cancer

Marianne Kim, Natasha Caplen, Sirisha Chakka, Lidia Hernandez, Carrie House, Georgios Pongas, Elizabeth Jordan & Christina Annunziata
Two-way ANOVA with REGWQ post-hoc test for cisplatin dose effect. (PPTX 65Â kb)

Additional file 6: Movie S4. of Growth of human breast tissues from patient cells in 3D hydrogel scaffolds

Ethan Sokol, Daniel Miller, Anne Breggia, Kevin Spencer, Lisa Arendt & Piyush Gupta
Time-lapse microscopy depicting dynamic cellular migration in a growing organoid. The arrows indicate the direction of mass migration away from the leading edge of one duct and into another elongating duct. At the outset of the movie, the organoid had been grown for 8Â days. Images were captured every 10Â minutes. Frame rate: eight frames per second. (AVI 7540 kb)

Additional file 4: Movie S2. of Growth of human breast tissues from patient cells in 3D hydrogel scaffolds

Ethan Sokol, Daniel Miller, Anne Breggia, Kevin Spencer, Lisa Arendt & Piyush Gupta
Time-lapse microscopy depicting a rotating lobule and the behavior of leader cells. The arrow indicates the direction of rotation of the lobule on the left. Arrowheads indicate the location of leader cells extending from two elongating outgrowths. At the outset of the movie, the organoid had been grown for 8Â days. Images were captured every 10Â minutes. Frame rate: eight frames per second. (AVI 9677 kb)

Additional file 11: Figure S5. of Identification of therapeutic targets applicable to clinical strategies in ovarian cancer

Marianne Kim, Natasha Caplen, Sirisha Chakka, Lidia Hernandez, Carrie House, Georgios Pongas, Elizabeth Jordan & Christina Annunziata
Two-way ANOVA with Dunnett post-hoc comparing sequential exposure to BI6727 and MK1775. (PPTX 70Â kb)

MOESM1 of Fast virtual histology using X-ray in-line phase tomography: application to the 3D anatomy of maize developing seeds

David Rousseau, Thomas Widiez, Sylvaine Tommaso, Hugo Rositi, Jerome Adrien, Eric Maire, Max Langer, CÊcile Olivier, FrançOise Peyrin & Peter Rogowsky
Additional file 1. 3D segmentation of the maize seed at the four developmental stages.

Additional file 5: Movie S3. of Growth of human breast tissues from patient cells in 3D hydrogel scaffolds

Ethan Sokol, Daniel Miller, Anne Breggia, Kevin Spencer, Lisa Arendt & Piyush Gupta
Time-lapse microscopy depicting dynamic cellular migration in a growing organoid. The arrows indicate the direction of mass migration along two elongating ducts from the core of the organoid toward the leading edge of the ducts. At the outset of the movie, the organoid had been grown for 8Â days. Images were captured every 10Â minutes. Frame rate: eight frames per second. (AVI 5319 kb)

Additional file 3: Movie S1. of Growth of human breast tissues from patient cells in 3D hydrogel scaffolds

Ethan Sokol, Daniel Miller, Anne Breggia, Kevin Spencer, Lisa Arendt & Piyush Gupta
Confocal Z-series panning through the duct depicted in Fig. 2c (right). Z fields are separated by 1.11 μm, spanning a total of 71.94 μm. Note that the exterior of the structure is completely encapsulated by the myoepithelial layer of cells (CK14, green) and that the luminal layer is restricted to the inner layer of cells (CK8/18, red). (AVI 202753 kb)

Additional file 7: Movie S5. of Growth of human breast tissues from patient cells in 3D hydrogel scaffolds

Ethan Sokol, Daniel Miller, Anne Breggia, Kevin Spencer, Lisa Arendt & Piyush Gupta
Twenty-four-hour time-lapse movie of an organoid growing in hydrogel. Still frames from this movie are depicted in Fig. 4d. At the outset of the movie, the organoid had been grown for 8 days. Images were captured every 10 minutes. Frame rate: eight frames per second. (AVI 19903 kb)

Additional file 7: of Serotonin promotes exploitation in complex environments by accelerating decision-making

Shachar Iwanir, Adam Brown, Stanislav Nagy, Dana Najjar, Alexander Kazakov, Kyung Lee, Alon Zaslaver, Erel Levine & David Biron
Movie S3. Wild-type foraging in a complex environment. The midline of a wild-type animal (black curve, circle denotes the head) as it forages on a grid of bacterial patches (grey). Patches are circled with a blue ring if they were encountered and a yellow ring while they are being exploited. Colored areas depict individual exploitation events (as in Additional file 5: Figure S4). The movie was sped up 100x as compared to real-time. (MOV 7325...

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