10 Works

Impact of mental disorders on the risk of atrial fibrillation in patients with diabetes mellitus: a nationwide population-based study

Nan Young Bae, So-Ryoung Lee, Eue-Keun Choi, Hyun Jin Ahn, Hyo-Jeong Ahn, Soonil Kwon, Kyung-Do Han, Kyu-Na Lee, Seil Oh & Gregory Y. H. Lip
Abstract Background It is unclear whether mental disorders are an independent risk factor for atrial fibrillation (AF) in patients with diabetes. We aimed to investigate whether patients with diabetes who have mental disorders have an increased risk for AF. Methods Using the Korea National Health Insurance Service database, we enrolled 2,512,690 patients diagnosed with diabetes without AF between 2009 and 2012. We assessed five mental disorders: depression, insomnia, anxiety, bipolar disorder, and schizophrenia. Newly diagnosed...

Transient ischemic attack events and incident cardiovascular and non-cardiovascular complications: Observations from a large diversified multimorbid cohort

Gregory YH Lip, Ash Genaidy, Cara Estes, Deborah McKay & Tina Falks
Background:Transient ischemic attack (TIA) is a strong signal prompting the incidence of future cardiovascular and non-cardiovascular complications, in light of recent debate on the so-called “stroke-heart syndrome.” We aimed to investigate the relation of TIAs to incident clinical events.Methods:Patients were drawn from three health plans with a wide spectrum of age groups and a wide mix of socio-economic/disability status. Two TIA cohorts in a retrospective design were used to achieve the study specific aims: (i)...

Association between metabolically healthy obesity and risk of atrial fibrillation: taking physical activity into consideration

Ruoting Wang, Ivan Olier, Sandra Ortega-Martorell, Yingxin Liu, Zebing Ye, Gregory YH Lip & Guowei Li
Abstract The modification of physical activity (PA) on the metabolic status in relation to atrial fibrillation (AF) in obesity remains unknown. We aimed to investigate the independent and joint associations of metabolic status and PA with the risk of AF in obese population. Based on the data from UK Biobank study, we used Cox proportional hazards models for analyses. Metabolic status was categorized into metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO). PA was...

Molecular biomarkers predicting newly detected atrial fibrillation after ischaemic stroke or TIA: A systematic review

Kirsty Ward, Andy Vail, Alan Cameron, Mira Katan, Gregory YH Lip, Jesse Dawson, Craig J Smith & Amit K Kishore
Background:Several molecular biomarkers are available that predict newly detected atrial fibrillation (NDAF). We aimed to identify such biomarkers that predict NDAF after an Ischaemic stroke (IS)/Transient Ischaemic Attack (TIA) and evaluate their performance.Methods:A systematic review was undertaken in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies of patients with IS, TIA, or both, who underwent ECG monitoring for ⩾24 h, which reported molecular biomarkers and frequency of NDAF after...

Effectiveness of early rhythm control in improving clinical outcomes in patients with atrial fibrillation: a systematic review and meta-analysis

Wengen Zhu, Zexuan Wu, Yugang Dong, Gregory Y. H. Lip & Chen Liu
Abstract Background Current guidelines recommend rhythm control for improving symptoms and quality of life in symptomatic patients with atrial fibrillation (AF). However, the long-term prognostic outcomes of rhythm control compared with rate control are still inconclusive. In this meta-analysis, we aimed to assess the effects of early rhythm control compared with rate control on clinical outcomes in newly diagnosed AF patients. Methods We systematically searched the PubMed and Embase databases up to August 2022 for...

Impact of mental disorders on the risk of atrial fibrillation in patients with diabetes mellitus: a nationwide population-based study

Nan Young Bae, So-Ryoung Lee, Eue-Keun Choi, Hyun Jin Ahn, Hyo-Jeong Ahn, Soonil Kwon, Kyung-Do Han, Kyu-Na Lee, Seil Oh & Gregory Y. H. Lip
Abstract Background It is unclear whether mental disorders are an independent risk factor for atrial fibrillation (AF) in patients with diabetes. We aimed to investigate whether patients with diabetes who have mental disorders have an increased risk for AF. Methods Using the Korea National Health Insurance Service database, we enrolled 2,512,690 patients diagnosed with diabetes without AF between 2009 and 2012. We assessed five mental disorders: depression, insomnia, anxiety, bipolar disorder, and schizophrenia. Newly diagnosed...

Association between metabolically healthy obesity and risk of atrial fibrillation: taking physical activity into consideration

Ruoting Wang, Ivan Olier, Sandra Ortega-Martorell, Yingxin Liu, Zebing Ye, Gregory YH Lip & Guowei Li
Abstract The modification of physical activity (PA) on the metabolic status in relation to atrial fibrillation (AF) in obesity remains unknown. We aimed to investigate the independent and joint associations of metabolic status and PA with the risk of AF in obese population. Based on the data from UK Biobank study, we used Cox proportional hazards models for analyses. Metabolic status was categorized into metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO). PA was...

Effectiveness of early rhythm control in improving clinical outcomes in patients with atrial fibrillation: a systematic review and meta-analysis

Wengen Zhu, Zexuan Wu, Yugang Dong, Gregory Y. H. Lip & Chen Liu
Abstract Background Current guidelines recommend rhythm control for improving symptoms and quality of life in symptomatic patients with atrial fibrillation (AF). However, the long-term prognostic outcomes of rhythm control compared with rate control are still inconclusive. In this meta-analysis, we aimed to assess the effects of early rhythm control compared with rate control on clinical outcomes in newly diagnosed AF patients. Methods We systematically searched the PubMed and Embase databases up to August 2022 for...

Molecular biomarkers predicting newly detected atrial fibrillation after ischaemic stroke or TIA: A systematic review

Kirsty Ward, Andy Vail, Alan Cameron, Mira Katan, Gregory YH Lip, Jesse Dawson, Craig J Smith & Amit K Kishore
Background:Several molecular biomarkers are available that predict newly detected atrial fibrillation (NDAF). We aimed to identify such biomarkers that predict NDAF after an Ischaemic stroke (IS)/Transient Ischaemic Attack (TIA) and evaluate their performance.Methods:A systematic review was undertaken in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies of patients with IS, TIA, or both, who underwent ECG monitoring for ⩾24 h, which reported molecular biomarkers and frequency of NDAF after...

Transient ischemic attack events and incident cardiovascular and non-cardiovascular complications: Observations from a large diversified multimorbid cohort

Gregory YH Lip, Ash Genaidy, Cara Estes, Deborah McKay & Tina Falks
Background:Transient ischemic attack (TIA) is a strong signal prompting the incidence of future cardiovascular and non-cardiovascular complications, in light of recent debate on the so-called “stroke-heart syndrome.” We aimed to investigate the relation of TIAs to incident clinical events.Methods:Patients were drawn from three health plans with a wide spectrum of age groups and a wide mix of socio-economic/disability status. Two TIA cohorts in a retrospective design were used to achieve the study specific aims: (i)...

Registration Year

  • 2022
    10

Resource Types

  • Collection
    10

Affiliations

  • Liverpool Heart and Chest Hospital
    10
  • Aalborg University
    10
  • University of Modena and Reggio Emilia
    4
  • University of Birmingham
    4
  • Seoul National University
    4
  • University of Liverpool
    4
  • Sun Yat-sen University
    2
  • St Joseph's Health Centre
    2
  • Soongsil University
    2
  • Xi'an Jiaotong University
    2