2,971 Works

Multifunctional transmission polarization conversion metasurface based on dislocation induced anisotropy at terahertz frequency

Wenpeng Guo, Peng Tan, Jing Wang, Li Li, Shuai Li, Guanchao Wang, Zhongxiang Zhou & Hao Tian
Manipulating the polarization state of terahertz waves is critical for terahertz communication systems. In this study, a terahertz band polarization conversion metasurface based on dislocation-induced anisotropy is proposed. Numerical simulation results revealed that the polarization conversion of orthogonal linearly polarized light, left and right circularly polarized light, linearly polarized light to circularly polarized light, and circularly polarized light to linearly polarized light can be realized. Furthermore, the simulation revealed that multifunctional polarization conversion can be...

Following Other People’s Footsteps: A Contextual-Attraction Effect Induced by Biological Motion

Yuhui Cheng, Wenjie Liu, Xiangyong Yuan & Yi Jiang
Our visual system is bombarded with numerous social interactions that form intangible social bonds among people, as exemplified by synchronized walking in crowds. Here, we investigated whether these perceived social bonds implicitly intrude on visual perception and induce a contextual effect. Using multiple point-light walkers and a classical contextual paradigm, we tested 72 college-age adults across six experiments and found that the perceived direction of the central walker was attracted toward the direction of the...

Fault diagnosis of reciprocating compressor based on the prediction of comprehensive index extracted from the expansion process in indicator diagram

Weifeng Wu, Chengyi Li, Jing Zhang, Yin Zhang, Xiaoran Li, Yifan Yang, Zhongqing Zhu & Bingsheng Wang
The fault of vulnerable parts in the cylinder accounts for a large proportion of the fault of the reciprocating compressor. In order to find the fault of the compressor in time, parameter monitoring is usually applied to give forewarning or warning of the compressor fault. Because the setting of forewarning value relies on experiences, over protection and delayed warning events often occur. Recently, the research of fault diagnosis methods combined with artificial intelligence technology is...

Continuous variable spin-orbit total angular momentum entanglement on higher-order Poincaré sphere

Hui Guo, Na Liu, Hengxin Sun, Kui Liu & Jiangrui Gao
Optical spin–orbit coupling is an important phenomenon and have fruitful applications. Here, we investigate the spin-orbit total angular momentum entanglement in the optical parametric down-conversion process. Four pairs of entangled vector vortex modes are experimentally generated directly using a dispersion- and astigmatism-compensated single optical parametric oscillator, and for the first time, the spin-orbit quantum states are characterized on the quantum higher-order Poincaré sphere, and the relationship of spin-orbit total angular momentum Stokes entanglement is demonstrated....

Continuous variable spin-orbit total angular momentum entanglement on higher-order Poincaré sphere

Hui Guo, Na Liu, Hengxin Sun, Kui Liu & Jiangrui Gao
Optical spin–orbit coupling is an important phenomenon and have fruitful applications. Here, we investigate the spin-orbit total angular momentum entanglement in the optical parametric down-conversion process. Four pairs of entangled vector vortex modes are experimentally generated directly using a dispersion- and astigmatism-compensated single optical parametric oscillator, and for the first time, the spin-orbit quantum states are characterized on the quantum higher-order Poincaré sphere, and the relationship of spin-orbit total angular momentum Stokes entanglement is demonstrated....

Ultra-Sensitive Temperature and Pressure Sensor Based on PDMS-based FPI and Vernier-effect

Jiao Song, Simei Sun, Chao Jiang, Ning Chen, Wenbo Jiang, Changning Liu, Jie Ren & Saiyu Wang
An ultra-sensitive sensor, based on cascaded Polydimethylsiloxane (PDMS) and capillary cavities, has been realized for simultaneous temperature and gas pressure . A PDMS-based Fabry-Perot Interferometer (FPI1) with free spectral range (FSR1) of 4.40 nm was used as a sensing cavity, the sensitivity of which to temperature and pressure is 0.65 nm/℃ and 4.64 nm/MPa, respectively. A capillary-based FPI2 with FSR2=4.24 nm was used as a reference cavity, which is insensitive to neither temperature nor pressure....

Ultra-Sensitive Temperature and Pressure Sensor Based on PDMS-based FPI and Vernier-effect

Jiao Song, Simei Sun, Chao Jiang, Ning Chen, Wenbo Jiang, Changning Liu, Jie Ren & Saiyu Wang
An ultra-sensitive sensor, based on cascaded Polydimethylsiloxane (PDMS) and capillary cavities, has been realized for simultaneous temperature and gas pressure . A PDMS-based Fabry-Perot Interferometer (FPI1) with free spectral range (FSR1) of 4.40 nm was used as a sensing cavity, the sensitivity of which to temperature and pressure is 0.65 nm/℃ and 4.64 nm/MPa, respectively. A capillary-based FPI2 with FSR2=4.24 nm was used as a reference cavity, which is insensitive to neither temperature nor pressure....

Highly-time-resolved FMCW LiDAR with synchronously-nonlinearity-corrected acquisition for dynamic locomotion

Caiming Sun, Zhen chen, Shusheng Ye, Jing Lin, Wu Shi, Binghui Li, Fei Teng, Xuejin Li & Aidong Zhang
Highly-time-resolved and precise tracking for position, velocity and acceleration is urgently required when highly dynamic legged robots are walking, trotting and jumping. Frequency-modulated continuous-wave (FMCW) laser ranging is able to provide precise measurement in short distance. However, FMCW light detection and ranging (LiDAR) suffers from a low acquisition rate and poor linearity of laser frequency modulation in wide bandwidth. A sub-millisecond-scale acquisition rate and nonlinearity correction in the wide frequency modulation bandwidth have not been...

Endovascular Stent Graft Repair for Mycotic Aorto-Iliac Aneurysm Due to Brucella

Jianjun Jiang, Wenchong Shao, Shuohao Shen, Guangzhen Li, Yang Liu, Xiangjiu Ding & Qingbo Su
Purpose:Brucella aneurysms are very rare but life-threatening, and a standard treatment approach has yet to be established. The current study aimed to assess the safety and efficacy of endovascular treatment for Brucella aneurysms.Materials and Methods:The clinical data of 15 Brucella aortic-iliac aneurysm patients who underwent endovascular repair at 2 hospitals from January 2012 to December 2021 were retrospectively collected and analyzed.Results:Fifteen patients (12 men and 3 women) with a mean age of 59.3 years were...

Complex optically computed phase microscopy for label-free sub-cellular imaging

Xuan Liu, yuwei liu, Shupei Yu & Yuanwei Zhang
In this study, we investigated a complex optically computed phase microscopy (complex-OCPM) technology. Based on a low coherence interferometer and an innovative optical computation approach, the complex-OCPM imaging system achieves depth resolved quantitative phase measurement. Particularly, the complex-OCPM imaging system directly measures the complex amplitude of the optical field emerging from the sample, extracts the phase as the argument of a complex signal, and achieves a high spatial resolution in phase imaging. We evaluated the...

Direct wavefront sensing with a plenoptic sensor based on deep learning

Chen Hao, Haobo Zhang, Yi He, Ling WEI, Jinsheng Yang, Xiqi Li, Huang Linhai & Wei Kai
Traditional plenoptic wavefront sensors (PWS) suffer from the obvious step change of the slope response which leads to the poor performance of phase retrieval. In this paper, a neural network model combining the transformer architecture with U-Net model is utilized to restore wavefront directly from the plenoptic image of PWS. The results show that the averaged root mean square of residual wavefront error is less than 1/14λ (Marechal criterion), proving the proposed method successfully breaks...

Impact of atmospheric pressure variations on aerobic biodegradation test

Gangjin Liu, Balázs Frankó, Sten Strömberg, Dan Zheng, Mihaela Nistor, Jing Liu & Liangwei Deng
Biodegradation rate is an important index to evaluate the environmental risk of chemicals, which is usually determined by measuring oxygen consumption through respirometer in a biodegradation test. However, atmospheric pressure variations affect reactor oxygen concentration and oxygen volume recorded by respirometer in biodegradation test, and the parameters of reactor volume and test material amount amplify its effect. Atmospheric pressure variation >1 kPa could introduce >20% underestimation in biodegradation rate when a small amount of test...

Supplementary material from \"Patient-specific induced pluripotent stem cell properties implicate Ca2+-homeostasis in clinical arrhythmia associated with combined heterozygous RYR2 and SCN10A variants\"

Yafei Zhou, Wenjun Huang, Leiying Liu, Anmao Li, Congshan Jiang, Rui Zhou, Jie Wang, Xiaoqiu Tan, Christopher L.-H. Huang & Yanmin Zhang
We illustrate use of induced pluripotent stem cells (iPSCs) as platforms for investigating cardiomyocyte phenotypes in a human family pedigree exemplified by novel heterozygous RYR2-A1855D and SCN10A-Q1362H variants occurring alone and in combination. The proband, a four-month-old boy, presented with polymorphic ventricular tachycardia. Genetic tests revealed double novel heterozygous RYR2-A1855D and SCN10A-Q1362H variants inherited from his father (F) and mother (M), respectively. His father showed ventricular premature beats; his mother was asymptomatic. Molecular biological characterizations...

User-Generated Physician Ratings and Their Effects on Patients’ Physician Choices: Evidence from Yelp

Yiwei Chen & Stephanie Lee
Patients increasingly rely on online physician ratings to select their physicians and make health care decisions. However, it is unclear whether online physician ratings signal physician quality information and affect patients’ physician choices. By combining physician rating data from Yelp with data from Medicare, which covers a large elderly patient group, the authors find that ratings are positively associated with important measures of physician quality, including physicians’ credentials, adherence to clinical guidelines, and patients’ health...

SENP3 facilitates M1 macrophage polarization via the HIF-1α/PKM2 axis in lipopolysaccharide-induced acute lung injury

Shuangjun He, Chenyu Fan, Yiming Ji, Qian Su, Feng Zhao, Cuiying Xie, Xuelian Chen, Yang Zhang & Yi Chen
M1/M2 macrophage polarization plays a pivotal role in the development of acute lung injury (ALI). The hypoxia-inducible factor-1α/pyruvate kinase M2 (HIF-1α/PKM2) axis, which functions upstream of macrophage polarization, has been implicated in this process. The function of HIF-1α is known to be tightly regulated by SUMOylation. Upregulation of SUMO-specific peptidase 3 (SENP3), a deSUMOylation enzyme, is induced by reactive oxygen species (ROS), which are abundantly produced during ALI. To explore the links between SENP3, macrophage...

A phase Ia dose-escalation trial of Ametumumab (a fully human monoclonal antibody against epidermal growth factor receptor) in patients with advanced solid malignancies

Da Li, Hong Pan, Wei Wang, Yanan Xue, Yong Fang, Haizhou Lou, Qin Pan, Wei Jin, Yu Zheng, Weidong Han, Kongli Zhu, Xianfeng Zhao, Rong Xu, Jin Han & Hongming Pan
Background:Epidermal growth factor receptor (EGFR) is a well-known target for cancer treatment. However, the authorized anti-EGFR monoclonal antibodies generally cause several toxic effects, especially severe cutaneous toxicities as well as infusion reactions, and the clinical indications are limited. Here we developed Ametumumab, a fully human recombinant anti-EGFR monoclonal antibody.Objectives:To assess the safety, tolerability, pharmacokinetics (PK), and immunogenicity of Ametumumab.Design:A first-in-human phase Ia dose escalation study of Ametumumab in patients with advanced solid malignancies.Methods:An open-label, first-in-human...

A phase Ia dose-escalation trial of Ametumumab (a fully human monoclonal antibody against epidermal growth factor receptor) in patients with advanced solid malignancies

Da Li, Hong Pan, Wei Wang, Yanan Xue, Yong Fang, Haizhou Lou, Qin Pan, Wei Jin, Yu Zheng, Weidong Han, Kongli Zhu, Xianfeng Zhao, Rong Xu, Jin Han & Hongming Pan
Background:Epidermal growth factor receptor (EGFR) is a well-known target for cancer treatment. However, the authorized anti-EGFR monoclonal antibodies generally cause several toxic effects, especially severe cutaneous toxicities as well as infusion reactions, and the clinical indications are limited. Here we developed Ametumumab, a fully human recombinant anti-EGFR monoclonal antibody.Objectives:To assess the safety, tolerability, pharmacokinetics (PK), and immunogenicity of Ametumumab.Design:A first-in-human phase Ia dose escalation study of Ametumumab in patients with advanced solid malignancies.Methods:An open-label, first-in-human...

Association between basilar artery stenosis features, vertebral artery stenosis and perforator stroke after stenting

Rui Huang, Bo Yang, Feng Gao, Dapeng Mo, Ming Yang, Zhikai Hou, Yifan Liu, Rongrong Cui, Kaijiang Kang, Weibin Gu, Jianfeng He, Xin Lou, Zhongrong Miao & Ning Ma
Background and PurposeWe investigated the relationship between basilar artery (BA) atherosclerotic stenosis features and vertebral artery (VA) stenosis and explored whether BA stenosis features are associated with perforator stroke after stenting.MethodsPatients with BA stenosis who underwent HRMRI and DSA were recruited. Patients were divided into proximal BA stenosis and middle-or-distal BA stenosis groups, and then subgroup analyses were performed based on whether they had VA stenosis. BA plaque features were evaluated by HRMRI. Artery stenosis...

Association between basilar artery stenosis features, vertebral artery stenosis and perforator stroke after stenting

Rui Huang, Bo Yang, Feng Gao, Dapeng Mo, Ming Yang, Zhikai Hou, Yifan Liu, Rongrong Cui, Kaijiang Kang, Weibin Gu, Jianfeng He, Xin Lou, Zhongrong Miao & Ning Ma
Background and PurposeWe investigated the relationship between basilar artery (BA) atherosclerotic stenosis features and vertebral artery (VA) stenosis and explored whether BA stenosis features are associated with perforator stroke after stenting.MethodsPatients with BA stenosis who underwent HRMRI and DSA were recruited. Patients were divided into proximal BA stenosis and middle-or-distal BA stenosis groups, and then subgroup analyses were performed based on whether they had VA stenosis. BA plaque features were evaluated by HRMRI. Artery stenosis...

Higher Levels of Tumour-Infiltrating Lymphocytes (TILs) are Associated with a Better Prognosis, While CDK5 Plays a Different Role Between Nonmetastatic and Metastatic Colonic Carcinoma

Qinghua Wang, Ruihua Yin, Xiaoxiao Chen, Bin Hu, Bingjing Jiang, Wanfen Tang, Xia Zhang, Xiayun Jin, Mingliang Ying & Jianfei Fu
ObjectiveWe investigated the prognostic value of cyclin-dependent kinase 5 (CDK5) in a true population-based cohort of patients with colon cancer.Methods1. Immunohistochemical (IHC) staining was used to retrospectively analyse the expression of CDK5 in colon cancer tissue samples of 296 patients. The χ2 test, Kaplan-Meier method and Cox proportional regression model were used to analyse the difference between the patients with differential expression of CDK5 and with different stages (metastatic and nonmetastatic); 2. The number of...

Supplementary material from \"Domestication affects sex-biased gene expression evolution in the duck\"

Hongchang Gu, Liang Wang, Xueze Lv, Weifang Yang, Li Zhang, Zebin Zhang, Tao Zhu, Yaxiong Jia, Yu Chen & Lujiang Qu
Genes with sex-biased expression are thought to underlie sexually dimorphic phenotypes and are therefore subject to different selection pressures in males and females. Many authors have proposed that sexual conflict leads to the evolution of sex-biased expression, which allows males and females to reach separate phenotypic and fitness optima. The selection pressures associated with domestication may cause changes in population architectures and mating systems, which in turn can alter their direction and strength. We compared...

Changes in Patient Perceptions of the Provider Most Involved in Care During COVID-19 and Corresponding Effects on Patient Trust

Megan Ren, Hui Zhang, David Meltzer, Vineet M. Arora & Micah Prochaska
During COVID-19 routine clinical operations were disrupted, including limits on the types of providers allowed to perform in-person care and frequency of times they could enter a patient's room. Whether these changes affected patients’ trust in the care they received during hospitalization is unknown. Hospitalized patients on the general medicine service were called after discharge and asked to identify who (attending, resident, etc.) was most involved in their inpatient care, and how much trust they...

Spontaneous hepatic haemorrhage after caesarean section in a patient with uraemia and superimposed preeclampsia: a case report

Yuanyuan Chen, Kai Liu, Kangjie Song, Changtai Fang, Lianghua Zhu, Gaofei Wu, Junjing Zha & Jiaan Zha
Perinatal spontaneous hepatic haemorrhage is a very rare disease affecting pregnant women, particularly those on long-term dialysis, that has a high maternal and infant mortality rate. Most patients experience preeclampsia with haemolysis, elevated liver enzymes and low platelets syndrome. Here, the case of a 35-year-old multigravida patient with known chronic kidney disease and chronic hypertension with uraemia, who developed spontaneous hepatic haemorrhage after caesarean section, is described. The patient experienced sudden massive circulatory failure, but...

Multiplex Immunofluorescence Image Quality Checking Using DAPI Channel–referenced Evaluation

Jun Jiang, Raymond Moore, Clarissa E. Jordan, Ruifeng Guo, Rachel L. Maus, Hongfang Liu, Ellen Goode, Svetomir N. Markovic & Chen Wang
Multiplex immunofluorescence (MxIF) images provide detailed information of cell composition and spatial context for biomedical research. However, compromised data quality could lead to research biases. Comprehensive image quality checking (QC) is essential for reliable downstream analysis. As a reliable and specific staining of cell nuclei, 4′,6-diamidino-2-phenylindole (DAPI) signals were used as references for tissue localization and auto-focusing across MxIF staining–scanning–bleaching iterations and could potentially be reused for QC. To confirm the feasibility of using DAPI...

Fourier ptychographic topography

Hao Wang, Jiabei Zhu, Jangwoon Sung, Guorong Hu, Joseph Greene, Yunzhe Li, Seungbeom Park, WOOKRAE KIM, Myungjun Lee & Yusin Yang
Topography measurement is essential for surface characterization, semiconductor metrology, and inspection applications. To date, performing high-throughput and accurate topography remains challenging due to the trade-off between field-of-view (FOV) and spatial resolution. Here we demonstrate a novel topography technique based on the reflection-mode Fourier ptychographic microscopy, termed Fourier ptychograhpic topography (FPT). We show that FPT provides both a wide FOV and high resolution, and achieves nanoscale height reconstruction accuracy. Our FPT prototype is based on a...

Registration Year

  • 2023
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Affiliations

  • Sun Yat-sen University
    2,971
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    1,990
  • Shanghai Jiao Tong University
    1,988
  • Zhejiang University
    1,839
  • Fudan University
    1,830
  • Sichuan University
    1,772
  • Capital Medical University
    1,642
  • Huazhong University of Science and Technology
    1,636
  • Chinese Academy of Sciences
    1,589
  • Nanjing Medical University
    1,440