22 Works

Theoretical analysis of 60-W solar-pumped single crystal fiber laser

Pengfei Xiang, Lanling Lan, Yan Liu, Hongfei Qi, Yulong Tang & xiuhua ma
In order to improve the output power of solar-pumped single-crystal fiber (SCF) lasers, a novel solar concentrating system is proposed, which consists of a parabolic mirror, a 3D-CPC, and a hollow-core reflector. By ray tracing with TracePro, influence of the fiber’s diameter and the hollow reflector’s shape on the solar absorption efficiency is theoretically investigated. A typical Nd:YAG SCF with a core-diameter of 1 mm, length of 150 mm and doping concentration of 1 at.%...

Epidemiological and etiological characteristics of mild hand, foot and mouth disease in children under 7 years old, Nanjing, China, 2010–2019

Junjun Wang, Songning Ding, Weijia Xie, Taiwu Wang, Ying Qin, Jiandong Zheng, Xiaokun Yang, Hongting Zhao, Zhibin Peng & Tao Ma
Abstract Background Mild hand, foot and mouth disease (HFMD) cases make up a relatively high proportion of HFMD while have often been overlooked. This study aimed to investigate the epidemiological and etiological characteristics of mild HFMD in Nanjing. Methods Data on mild HFMD cases, during 2010–2019 in Nanjing, were collected from the China Information System for Disease Control and Prevention. This study mainly focused on mild cases aged < 7 years. Descriptive analysis was used...

Mechanical artifacts in optical projection tomography: classification and automatic calibration

Yan Liu, Jonathan Dong, Thanh-An Pham, Francois Marelli & Michael Unser
Optical projection tomography (OPT) is a powerful tool for biomedical studies. It achieves 3D visualization of mesoscopic biological samples with high spatial resolution using conventional tomographic-reconstruction algorithms. However, various artifacts degrade the quality of the reconstructed images due to experimental imperfections in the OPT instruments. While many efforts have been made to characterize and correct for these artifacts, they focus on one specific type of artifacts, whereas a comprehensive catalog of all sorts of mechanical...

Mechanical artifacts in optical projection tomography: classification and automatic calibration

Yan Liu, Jonathan Dong, Thanh-An Pham, Francois Marelli & Michael Unser
Optical projection tomography (OPT) is a powerful tool for biomedical studies. It achieves 3D visualization of mesoscopic biological samples with high spatial resolution using conventional tomographic-reconstruction algorithms. However, various artifacts degrade the quality of the reconstructed images due to experimental imperfections in the OPT instruments. While many efforts have been made to characterize and correct for these artifacts, they focus on one specific type of artifacts, whereas a comprehensive catalog of all sorts of mechanical...

Supracapsular scleral sutured intraocular lens implantation in anterior segment dysgenesis patients with ectopia lentis

Tian-Hui Chen, Ling-hao Song, Lei Jiang, Ye zhao, Yan Liu, Dong-jin Qian, Ze-xu Chen & Yong-Xiang Jiang
ObjectiveTo describe a new strategy to manage ectopia lentis in ASD patients assessing the visual outcomes and safety of supracapsular scleral sutured intraocular lens implantation and analyzing the accuracy of different intraocular lens (IOL) power calculation formulae.MethodsEight patients with ASD (13 eyes) were underwent supracapsular scleral suture fixation of posterior chamber (PC) IOL without capsular extirpation. The preoperative and postoperative clinical features were compared. The prediction error values from four formulae (SRK/T, Holladay 1, Hoffer...

Epidemiological and etiological characteristics of mild hand, foot and mouth disease in children under 7 years old, Nanjing, China, 2010–2019

Junjun Wang, Songning Ding, Weijia Xie, Taiwu Wang, Ying Qin, Jiandong Zheng, Xiaokun Yang, Hongting Zhao, Zhibin Peng & Tao Ma
Abstract Background Mild hand, foot and mouth disease (HFMD) cases make up a relatively high proportion of HFMD while have often been overlooked. This study aimed to investigate the epidemiological and etiological characteristics of mild HFMD in Nanjing. Methods Data on mild HFMD cases, during 2010–2019 in Nanjing, were collected from the China Information System for Disease Control and Prevention. This study mainly focused on mild cases aged < 7 years. Descriptive analysis was used...

High-yield production of protopanaxadiol from sugarcane molasses by metabolically engineered Saccharomyces cerevisiae

Yuan Zhu, Jianxiu Li, Longyun Peng, Lijun Meng, Mengxue Diao, Shuiyuan Jiang, Jianbin Li & Nengzhong Xie
Abstract Background Ginsenosides are Panax plant-derived triterpenoid with wide applications in cardiovascular protection and immunity-boosting. However, the saponins content of Panax plants is fairly low, making it time-consuming and unsustainable by direct extraction. Protopanaxadiol (PPD) is a common precursor of dammarane-type saponins, and its sufficient supply is necessary for the efficient synthesis of ginsenoside. Results In this study, a combinational strategy was used for the construction of an efficient yeast cell factory for PPD production....

Deep learning-enabled volumetric cone photoreceptor segmentation in adaptive optics optical coherence tomography images of normal and diseased eyes

Somayyeh Soltanian-Zadeh, Zhuolin Liu, Yan Liu, Ayoub Lassoued, Catherine Cukras, Donald Miller, Daniel Hammer & Sina Farsiu
Objective quantification of photoreceptor cell morphology, such as cell diameter and outer segment length, is crucial for early, accurate, and sensitive diagnosis and prognosis of retinal neurodegenerative diseases. Adaptive optics optical coherence tomography (AO-OCT) provides three-dimensional (3-D) visualization of photoreceptor cells in the living human eye. The current gold standard for extracting cell morphology from AO-OCT images involves the tedious process of 2-D manual marking. To automate this process and extend to 3-D analysis of...

Specific triacylglycerol, diacylglycerol, and lyso-phosphatidylcholine species for the prediction of type 2 diabetes: a ~ 16-year prospective study in Chinese

Junda Zhong, Chloe Y. Y. Cheung, Xiuli Su, Chi-Ho Lee, Yi Ru, Carol H. Y. Fong, Yan Liu, Cynthia K. Y. Cheung, Karen S. L. Lam, Zongwei Cai & Aimin Xu
Abstract Background Bioactive lipids play an important role in insulin secretion and sensitivity, contributing to the pathophysiology of type 2 diabetes (T2D). This study aimed to identify novel lipid species associated with incident T2D in a nested case–control study within a long-term prospective Chinese community-based cohort with a median follow-up of ~ 16 years. Methods Plasma samples from 196 incident T2D cases and 196 age- and sex-matched non-T2D controls recruited from the Hong Kong Cardiovascular...

Housekeeping gene gyrA, a potential molecular marker for Bacillus ecology study

Yan Liu, Polonca Štefanič, Youzhi Miao, Yansheng Xue, Weibing Xun, Nan Zhang, Qirong Shen, Ruifu Zhang, Zhihui Xu & Ines Mandic-Mulec
Abstract Bacillus is a genus of microorganisms (bacteria) and contains many important commercial species used in industry, agriculture and healthcare. Many different Bacilli are relatively well understood at the single-cell level; however, molecular tools that determine the diversity and ecology of Bacillus community are limited, which limits our understanding of how the Bacillus community works. In the present study, we investigated the potential of the housekeeping gene gyrA as a molecular marker for determining the...

Theoretical analysis of 60-W solar-pumped single crystal fiber laser

Pengfei Xiang, Lanling Lan, Yan Liu, Hongfei Qi, Yulong Tang & xiuhua ma
In order to improve the output power of solar-pumped single-crystal fiber (SCF) lasers, a novel solar concentrating system is proposed, which consists of a parabolic mirror, a 3D-CPC, and a hollow-core reflector. By ray tracing with TracePro, influence of the fiber’s diameter and the hollow reflector’s shape on the solar absorption efficiency is theoretically investigated. A typical Nd:YAG SCF with a core-diameter of 1 mm, length of 150 mm and doping concentration of 1 at.%...

Deep learning-enabled volumetric cone photoreceptor segmentation in adaptive optics optical coherence tomography images of normal and diseased eyes

Somayyeh Soltanian-Zadeh, Zhuolin Liu, Yan Liu, Ayoub Lassoued, Catherine Cukras, Donald Miller, Daniel Hammer & Sina Farsiu
Objective quantification of photoreceptor cell morphology, such as cell diameter and outer segment length, is crucial for early, accurate, and sensitive diagnosis and prognosis of retinal neurodegenerative diseases. Adaptive optics optical coherence tomography (AO-OCT) provides three-dimensional (3-D) visualization of photoreceptor cells in the living human eye. The current gold standard for extracting cell morphology from AO-OCT images involves the tedious process of 2-D manual marking. To automate this process and extend to 3-D analysis of...

Theoretical analysis of 60-W solar-pumped single crystal fiber laser

Pengfei Xiang, Lanling Lan, Yan Liu, Hongfei Qi, Yulong Tang & xiuhua ma
In order to improve the output power of solar-pumped single-crystal fiber (SCF) lasers, a novel solar concentrating system is proposed, which consists of a parabolic mirror, a 3D-CPC, and a hollow-core reflector. By ray tracing with TracePro, influence of the fiber’s diameter and the hollow reflector’s shape on the solar absorption efficiency is theoretically investigated. A typical Nd:YAG SCF with a core-diameter of 1 mm, length of 150 mm and doping concentration of 1 at.%...

Mechanical artifacts in optical projection tomography: classification and automatic calibration

Yan Liu, Jonathan Dong, Thanh-An Pham, Francois Marelli & Michael Unser
Optical projection tomography (OPT) is a powerful tool for biomedical studies. It achieves 3D visualization of mesoscopic biological samples with high spatial resolution using conventional tomographic-reconstruction algorithms. However, various artifacts degrade the quality of the reconstructed images due to experimental imperfections in the OPT instruments. While many efforts have been made to characterize and correct for these artifacts, they focus on one specific type of artifacts, whereas a comprehensive catalog of all sorts of mechanical...

Deep learning-enabled volumetric cone photoreceptor segmentation in adaptive optics optical coherence tomography images of normal and diseased eyes

Somayyeh Soltanian-Zadeh, Zhuolin Liu, Yan Liu, Ayoub Lassoued, Catherine Cukras, Donald Miller, Daniel Hammer & Sina Farsiu
Objective quantification of photoreceptor cell morphology, such as cell diameter and outer segment length, is crucial for early, accurate, and sensitive diagnosis and prognosis of retinal neurodegenerative diseases. Adaptive optics optical coherence tomography (AO-OCT) provides three-dimensional (3-D) visualization of photoreceptor cells in the living human eye. The current gold standard for extracting cell morphology from AO-OCT images involves the tedious process of 2-D manual marking. To automate this process and extend to 3-D analysis of...

Theoretical analysis of 60-W solar-pumped single crystal fiber laser

Pengfei Xiang, Lanling Lan, Yan Liu, Hongfei Qi, Yulong Tang & xiuhua ma
In order to improve the output power of solar-pumped single-crystal fiber (SCF) lasers, a novel solar concentrating system is proposed, which consists of a parabolic mirror, a 3D-CPC, and a hollow-core reflector. By ray tracing with TracePro, influence of the fiber’s diameter and the hollow reflector’s shape on the solar absorption efficiency is theoretically investigated. A typical Nd:YAG SCF with a core-diameter of 1 mm, length of 150 mm and doping concentration of 1 at.%...

Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Abstract Background The importance of fathers’ engagement in care and its critical role in the offspring’s cognitive and emotional development is now well established. Yet, little is known on the underlying neurobiology due to the lack of appropriate animal models. In the socially monogamous and bi-parental prairie vole (Microtus ochrogaster), while 60–80% of virgin males show spontaneous paternal behaviors (Paternal), others display pup-directed aggression (Attackers). Here we took advantage of this phenotypic dichotomy and used...

Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Abstract Background The importance of fathers’ engagement in care and its critical role in the offspring’s cognitive and emotional development is now well established. Yet, little is known on the underlying neurobiology due to the lack of appropriate animal models. In the socially monogamous and bi-parental prairie vole (Microtus ochrogaster), while 60–80% of virgin males show spontaneous paternal behaviors (Paternal), others display pup-directed aggression (Attackers). Here we took advantage of this phenotypic dichotomy and used...

Housekeeping gene gyrA, a potential molecular marker for Bacillus ecology study

Yan Liu, Polonca Štefanič, Youzhi Miao, Yansheng Xue, Weibing Xun, Nan Zhang, Qirong Shen, Ruifu Zhang, Zhihui Xu & Ines Mandic-Mulec
Abstract Bacillus is a genus of microorganisms (bacteria) and contains many important commercial species used in industry, agriculture and healthcare. Many different Bacilli are relatively well understood at the single-cell level; however, molecular tools that determine the diversity and ecology of Bacillus community are limited, which limits our understanding of how the Bacillus community works. In the present study, we investigated the potential of the housekeeping gene gyrA as a molecular marker for determining the...

High-yield production of protopanaxadiol from sugarcane molasses by metabolically engineered Saccharomyces cerevisiae

Yuan Zhu, Jianxiu Li, Longyun Peng, Lijun Meng, Mengxue Diao, Shuiyuan Jiang, Jianbin Li & Nengzhong Xie
Abstract Background Ginsenosides are Panax plant-derived triterpenoid with wide applications in cardiovascular protection and immunity-boosting. However, the saponins content of Panax plants is fairly low, making it time-consuming and unsustainable by direct extraction. Protopanaxadiol (PPD) is a common precursor of dammarane-type saponins, and its sufficient supply is necessary for the efficient synthesis of ginsenoside. Results In this study, a combinational strategy was used for the construction of an efficient yeast cell factory for PPD production....

Specific triacylglycerol, diacylglycerol, and lyso-phosphatidylcholine species for the prediction of type 2 diabetes: a ~ 16-year prospective study in Chinese

Junda Zhong, Chloe Y. Y. Cheung, Xiuli Su, Chi-Ho Lee, Yi Ru, Carol H. Y. Fong, Yan Liu, Cynthia K. Y. Cheung, Karen S. L. Lam, Zongwei Cai & Aimin Xu
Abstract Background Bioactive lipids play an important role in insulin secretion and sensitivity, contributing to the pathophysiology of type 2 diabetes (T2D). This study aimed to identify novel lipid species associated with incident T2D in a nested case–control study within a long-term prospective Chinese community-based cohort with a median follow-up of ~ 16 years. Methods Plasma samples from 196 incident T2D cases and 196 age- and sex-matched non-T2D controls recruited from the Hong Kong Cardiovascular...

Supracapsular scleral sutured intraocular lens implantation in anterior segment dysgenesis patients with ectopia lentis

Tian-Hui Chen, Ling-hao Song, Lei Jiang, Ye zhao, Yan Liu, Dong-jin Qian, Ze-xu Chen & Yong-Xiang Jiang
ObjectiveTo describe a new strategy to manage ectopia lentis in ASD patients assessing the visual outcomes and safety of supracapsular scleral sutured intraocular lens implantation and analyzing the accuracy of different intraocular lens (IOL) power calculation formulae.MethodsEight patients with ASD (13 eyes) were underwent supracapsular scleral suture fixation of posterior chamber (PC) IOL without capsular extirpation. The preoperative and postoperative clinical features were compared. The prediction error values from four formulae (SRK/T, Holladay 1, Hoffer...

Registration Year

  • 2023
    5
  • 2022
    17

Resource Types

  • Collection
    22

Affiliations

  • Guangxi Institute of Botany
    22
  • Shanghai Jiao Tong University
    20
  • Peking University
    20
  • Guilin Medical University
    18
  • Henan University
    18
  • Sun Yat-sen University
    18
  • National Institute of Diabetes and Digestive and Kidney Diseases
    18
  • Wuhan University of Science and Technology
    18
  • Southwest Medical University
    18
  • Jilin University
    18