8 Works
Content and strength of conflict of interest policies at Scandinavian medical schools: a cross sectional study
Alice Fabbri, Shai Mulinari, Martin Johansson, Weda Ghaur, Abdullah Muhammad Khalil & Andreas Lundh
Abstract Background Concerns around staffs’ and students’ interactions with commercial entities, for example drug companies, have led several North American medical schools to implement conflict of interest (COI) policies. However, little is known about COI policies at European medical schools. We analysed the content and strength of COI policies at Scandinavian medical schools. Methods We searched the websites of medical schools in Denmark, Norway, and Sweden and emailed the Deans for additional information. Using comparable...
Family-based cognitive behavioural therapy versus family-based relaxation therapy for obsessive-compulsive disorder in children and adolescents (the TECTO trial): a statistical analysis plan for the randomised clinical trial
Markus Harboe Olsen, Julie Hagstrøm, Nicole Nadine Lønfeldt, Camilla Uhre, Valdemar Uhre, Linea Pretzmann, Sofie Heidenheim Christensen, Christine Thoustrup, Nicoline Løcke Jepsen Korsbjerg, Anna-Rosa Cecilie Mora-Jensen, Melanie Ritter, Janus Engstrøm, Jane Lindschou, Hartwig Roman Siebner, Frank Verhulst, Pia Jeppesen, Jens Richardt Møllegaard Jepsen, Signe Vangkilde, Per Hove Thomsen, Katja Hybel, Line Katrine Harder Clemmesen, Christian Gluud, Kerstin Jessica Plessen, Anne Katrine Pagsberg & Janus Christian Jakobsen
Abstract Background Obsessive-compulsive disorder (OCD) is a debilitating psychiatric disorder which affects up to 3% of children and adolescents. OCD in children and adolescents is generally treated with cognitive behavioural therapy (CBT), which, in more severely affected patients, can be combined with antidepressant medication. The TECTO trial aims to compare the benefits and harms of family-based CBT (FCBT) versus family-based psychoeducation/relaxation training (FPRT) in children and adolescents aged 8 to 17 years. This statistical analysis...
Family-based cognitive behavioural therapy versus family-based relaxation therapy for obsessive-compulsive disorder in children and adolescents (the TECTO trial): a statistical analysis plan for the randomised clinical trial
Markus Harboe Olsen, Julie Hagstrøm, Nicole Nadine Lønfeldt, Camilla Uhre, Valdemar Uhre, Linea Pretzmann, Sofie Heidenheim Christensen, Christine Thoustrup, Nicoline Løcke Jepsen Korsbjerg, Anna-Rosa Cecilie Mora-Jensen, Melanie Ritter, Janus Engstrøm, Jane Lindschou, Hartwig Roman Siebner, Frank Verhulst, Pia Jeppesen, Jens Richardt Møllegaard Jepsen, Signe Vangkilde, Per Hove Thomsen, Katja Hybel, Line Katrine Harder Clemmesen, Christian Gluud, Kerstin Jessica Plessen, Anne Katrine Pagsberg & Janus Christian Jakobsen
Abstract Background Obsessive-compulsive disorder (OCD) is a debilitating psychiatric disorder which affects up to 3% of children and adolescents. OCD in children and adolescents is generally treated with cognitive behavioural therapy (CBT), which, in more severely affected patients, can be combined with antidepressant medication. The TECTO trial aims to compare the benefits and harms of family-based CBT (FCBT) versus family-based psychoeducation/relaxation training (FPRT) in children and adolescents aged 8 to 17 years. This statistical analysis...
Healthcare use and healthcare costs for patients with advanced cancer; the international ACTION cluster-randomised trial on advance care planning
Ida J Korfage, Suzanne Polinder, Nancy Preston, Johannes JM van Delden, Sandra (A)JLM Geraerds, Lesley Dunleavy, Kristof Faes, Guido Miccinesi, Giulia Carreras, Caroline Moeller Arnfeldt, Marijke C Kars, Giuseppe Lippi, Urska Lunder, Ceu Mateus, Kristian Pollock, Luc Deliens, Mogens Groenvold, Agnes van der Heide & Judith AC Rietjens
Background:Advance care planning supports patients to reflect on and discuss preferences for future treatment and care. Studies of the impact of advance care planning on healthcare use and healthcare costs are scarce.Aim:To determine the impact on healthcare use and costs of an advance care planning intervention across six European countries.Design:Cluster-randomised trial, registered as ISRCTN63110516, of advance care planning conversations supported by certified facilitators.Setting/participants:Patients with advanced lung or colorectal cancer from 23 hospitals in Belgium, Denmark,...
Healthcare use and healthcare costs for patients with advanced cancer; the international ACTION cluster-randomised trial on advance care planning
Ida J Korfage, Suzanne Polinder, Nancy Preston, Johannes JM van Delden, Sandra (A)JLM Geraerds, Lesley Dunleavy, Kristof Faes, Guido Miccinesi, Giulia Carreras, Caroline Moeller Arnfeldt, Marijke C Kars, Giuseppe Lippi, Urska Lunder, Ceu Mateus, Kristian Pollock, Luc Deliens, Mogens Groenvold, Agnes van der Heide & Judith AC Rietjens
Background:Advance care planning supports patients to reflect on and discuss preferences for future treatment and care. Studies of the impact of advance care planning on healthcare use and healthcare costs are scarce.Aim:To determine the impact on healthcare use and costs of an advance care planning intervention across six European countries.Design:Cluster-randomised trial, registered as ISRCTN63110516, of advance care planning conversations supported by certified facilitators.Setting/participants:Patients with advanced lung or colorectal cancer from 23 hospitals in Belgium, Denmark,...
Patient-reported outcome measures in systemic lupus erythematosus by a web-based application: A randomized, crossover, agreement study
Line Uhrenholt, Simone Høstgaard, Julie F Pedersen, Robin Christensen, Lene Dreyer, Henrik C B Leffers, Peter C Taylor, Vibeke Strand, Søren Jacobsen, Anne Voss, Jon W Gregersen & Salome Kristensen
ObjectivesPatient-reported outcome measures (PROMs) are evaluated in randomized controlled trials (RCTs) in patients with systemic lupus erythematosus (SLE), but not widely used in clinical practice. However, interest in incorporating PROMs into the management of SLE is increasing as PROMs provide a unique insight into the patient’s perception of lupus disease activity. The objective was to assess agreement in PROMs answered using a web app versus an outpatient touchscreen among patients with SLE.MethodsIn a crossover RCT,...
Patient-reported outcome measures in systemic lupus erythematosus by a web-based application: A randomized, crossover, agreement study
Line Uhrenholt, Simone Høstgaard, Julie F Pedersen, Robin Christensen, Lene Dreyer, Henrik C B Leffers, Peter C Taylor, Vibeke Strand, Søren Jacobsen, Anne Voss, Jon W Gregersen & Salome Kristensen
ObjectivesPatient-reported outcome measures (PROMs) are evaluated in randomized controlled trials (RCTs) in patients with systemic lupus erythematosus (SLE), but not widely used in clinical practice. However, interest in incorporating PROMs into the management of SLE is increasing as PROMs provide a unique insight into the patient’s perception of lupus disease activity. The objective was to assess agreement in PROMs answered using a web app versus an outpatient touchscreen among patients with SLE.MethodsIn a crossover RCT,...
Content and strength of conflict of interest policies at Scandinavian medical schools: a cross sectional study
Alice Fabbri, Shai Mulinari, Martin Johansson, Weda Ghaur, Abdullah Muhammad Khalil & Andreas Lundh
Abstract Background Concerns around staffs’ and students’ interactions with commercial entities, for example drug companies, have led several North American medical schools to implement conflict of interest (COI) policies. However, little is known about COI policies at European medical schools. We analysed the content and strength of COI policies at Scandinavian medical schools. Methods We searched the websites of medical schools in Denmark, Norway, and Sweden and emailed the Deans for additional information. Using comparable...