Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease characterized by excessive fat accumulation in the liver. One of the underlying pathophysiological mechanisms is insulin resistance (IR). Traditional Chinese medicine (TCM) has showed potential benefits in the management of NAFLD. Lingguizhugan decoction (LGZG) is a representative Chinese herbal formula; however, there is still no rigorous clinical trial supporting its application. Methods/design This study will be a three-arm, dose-optimization, randomized, double-blinded, placebo-controlled...

Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease characterized by excessive fat accumulation in the liver. One of the underlying pathophysiological mechanisms is insulin resistance (IR). Traditional Chinese medicine (TCM) has showed potential benefits in the management of NAFLD. Lingguizhugan decoction (LGZG) is a representative Chinese herbal formula; however, there is still no rigorous clinical trial supporting its application. Methods/design This study will be a three-arm, dose-optimization, randomized, double-blinded, placebo-controlled...

Aim:Some obstructive sleep apnea (OSA) patients may have mandibular retrognathia (ANB > 4.7° and SNB < 76.2°). Currently, there are no studies that have compared the effectiveness of continuous positive airway pressure (CPAP) versus mandibular advancement device (MAD) in severe OSA patients with mandibular retrognathia. We explored the efficacy of CPAP versus MAD for the treatment of severe OSA patients with mandibular retrognathia.Methods:A total of 105 patients were enrolled. Outcomes were assessed by using polysomnography,...

Aim:Some obstructive sleep apnea (OSA) patients may have mandibular retrognathia (ANB > 4.7° and SNB < 76.2°). Currently, there are no studies that have compared the effectiveness of continuous positive airway pressure (CPAP) versus mandibular advancement device (MAD) in severe OSA patients with mandibular retrognathia. We explored the efficacy of CPAP versus MAD for the treatment of severe OSA patients with mandibular retrognathia.Methods:A total of 105 patients were enrolled. Outcomes were assessed by using polysomnography,...

A new type of N-isopropyl acrylamide/high-substituted hydroxypropyl cellulose/graphite carbon nitride (NIPAAm/HHPC/g-C3N4) smart hydrogel-based photocatalyst with thermally driven characteristic was successfully prepared by electron beam pre-radiation polymerization and radiation cross-linking methods. The agglomeration and loss of g-C3N4 nanosheets can be avoided effectively, and ensured high photocatalytic activity under visible light, once the g-C3N4 nanosheets are uniformly dispersed into the skeleton of a thermosensitive NIPAAm/HHPC hydrogel. NIPAAm/HHPC/g-C3N4 (NHC) hydrogel was characterized by nuclear magnetic resonance spectroscopy, Fourier-transform...

A new type of N-isopropyl acrylamide/high-substituted hydroxypropyl cellulose/graphite carbon nitride (NIPAAm/HHPC/g-C3N4) smart hydrogel-based photocatalyst with thermally driven characteristic was successfully prepared by electron beam pre-radiation polymerization and radiation cross-linking methods. The agglomeration and loss of g-C3N4 nanosheets can be avoided effectively, and ensured high photocatalytic activity under visible light, once the g-C3N4 nanosheets are uniformly dispersed into the skeleton of a thermosensitive NIPAAm/HHPC hydrogel. NIPAAm/HHPC/g-C3N4 (NHC) hydrogel was characterized by nuclear magnetic resonance spectroscopy, Fourier-transform...