4 Works

Coating formulation change leads to inferior performance of long-lasting insecticidal nets in Papua New Guinea

Nakei Bubun, Evodia Anetul, Melanie Koinari, Timothy W. Freeman & Stephan Karl
Abstract Background Long-lasting insecticidal nets (LLINs) play a key role in reducing malaria transmission in endemic countries. In a previous study, the authors demonstrated a substantial decrease in the bioefficacy of LLINs for malaria prevention delivered to Papua New Guinea (PNG) between 2013 and 2019. This coincided with a rise in malaria cases in the country. The present study was aimed at determining the underlying cause of the reduced bioefficacy observed in these LLINs. The...

orsai, the Drosophila homolog of human ETFRF1, links lipid catabolism to growth control

Magdalena Fernandez-Acosta, Juan I. Romero, Guillermo Bernabó, Giovanna M. Velázquez-Campos, Nerina Gonzalez, M. Lucía Mares, Santiago Werbajh, L. Amaranta Avendaño-Vázquez, Gerald N. Rechberger, Ronald P. Kühnlein, Cristina Marino-Buslje, Rafael Cantera, Carolina Rezaval & M. Fernanda Ceriani
Abstract Background Lipid homeostasis is an evolutionarily conserved process that is crucial for energy production, storage and consumption. Drosophila larvae feed continuously to achieve the roughly 200-fold increase in size and accumulate sufficient reserves to provide all energy and nutrients necessary for the development of the adult fly. The mechanisms controlling this metabolic program are poorly understood. Results Herein we identified a highly conserved gene, orsai (osi), as a key player in lipid metabolism in...

Coating formulation change leads to inferior performance of long-lasting insecticidal nets in Papua New Guinea

Nakei Bubun, Evodia Anetul, Melanie Koinari, Timothy W. Freeman & Stephan Karl
Abstract Background Long-lasting insecticidal nets (LLINs) play a key role in reducing malaria transmission in endemic countries. In a previous study, the authors demonstrated a substantial decrease in the bioefficacy of LLINs for malaria prevention delivered to Papua New Guinea (PNG) between 2013 and 2019. This coincided with a rise in malaria cases in the country. The present study was aimed at determining the underlying cause of the reduced bioefficacy observed in these LLINs. The...

orsai, the Drosophila homolog of human ETFRF1, links lipid catabolism to growth control

Magdalena Fernandez-Acosta, Juan I. Romero, Guillermo Bernabó, Giovanna M. Velázquez-Campos, Nerina Gonzalez, M. Lucía Mares, Santiago Werbajh, L. Amaranta Avendaño-Vázquez, Gerald N. Rechberger, Ronald P. Kühnlein, Cristina Marino-Buslje, Rafael Cantera, Carolina Rezaval & M. Fernanda Ceriani
Abstract Background Lipid homeostasis is an evolutionarily conserved process that is crucial for energy production, storage and consumption. Drosophila larvae feed continuously to achieve the roughly 200-fold increase in size and accumulate sufficient reserves to provide all energy and nutrients necessary for the development of the adult fly. The mechanisms controlling this metabolic program are poorly understood. Results Herein we identified a highly conserved gene, orsai (osi), as a key player in lipid metabolism in...

Registration Year

  • 2022
    4

Resource Types

  • Collection
    4

Affiliations

  • University of Graz
    4
  • Papua New Guinea Institute of Medical Research
    2
  • Washington University in St. Louis
    2
  • BioTechMed-Graz
    2
  • University of Birmingham
    2
  • National Scientific and Technical Research Council
    2
  • James Cook University
    2
  • Instituto de Investigaciones Biológicas Clemente Estable
    2
  • Stockholm University
    2