In this paper, the adaptive liquid (AL) lenses are introduced into the double-sided telecentric zoom system, which could greatly decrease the mechanical motion group compared with the traditional zoom system, and only one movable STO is retained. Firstly, this paper derived the Gaussian brackets used in this system, and we found the appropriate screening method to get the suitable initial structure parameters from the solution space. Then we used the lens module design method to...

Time-delay reservoir computing uses a nonlinear node associated with a feedback loop to construct a large number of virtual neurons in the neural network. The clock cycle of the computing network is usually synchronous with the delay time of the feedback loop, which substantially constrains the flexibility of hardware implementations. This work shows an asynchronous reservoir computing network based on a semiconductor laser with an optical feedback loop, where the clock cycle is 20 ns...

Time-delay reservoir computing uses a nonlinear node associated with a feedback loop to construct a large number of virtual neurons in the neural network. The clock cycle of the computing network is usually synchronous with the delay time of the feedback loop, which substantially constrains the flexibility of hardware implementations. This work shows an asynchronous reservoir computing network based on a semiconductor laser with an optical feedback loop, where the clock cycle is 20 ns...

A binocular full-color holographic three-dimensional near eye display system using single SLM is proposed. In the display system, the frequency spectrum shifting operation and color spectrum shifting operation are adopted to realize the frequency division multiplexing (FDM) and frequency superposition multiplexing (FSM) by manipulating the frequency spectrums of each color- and view-channel sub-holograms. The FDM combined with polarization multiplexing will be used to implement binocular display using single SLM, and the FSM working with a...

ObjectiveTo conduct a systematic review and meta-analysis to compare the effects of statins and placebo on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in patients with hypertension.MethodsWe used different databases such as MEDLINE and the Cochrane Library Central Register of Controlled Trials (CENTRAL) to search for randomized controlled trials published from 1 January 2000 to 1 January 2022 to retrieve relevant studies and full-text articles evaluating statins versus placebo in patients with hypertension....

ObjectiveThis study aimed to provide a general overview of mental health randomized controlled trials (RCTs) and summarize the temporal trends in terms of the number of studies, median sample sizes, and median effect sizes using data collected from the Cochrane Database of Systematic Reviews (CDSR).MethodsUsing data collected from the CDSR, the temporal trends are compared in terms of the number of studies, median sample sizes, and median effect sizes between two broad categories of interventions:...

In order to understand the research status of the relationship between health communication and doctor-patient relationship, and to explore a new path of the impact of health communication on doctor-patient relationship, this paper adopted qualitative methods to quantize the literature over the past 10 years in the Web of Science database and carried out Co-Authorship Analysis, Co-Citation Analysis and Co-Occurrence Analysis based on CiteSpace. In addition, according to the results of bibliometric research, self-designed questionnaires...

This study explored pandemic-related social support profiles and investigated their relationships with depressive symptoms among Chinese parents during the COVID-19 pandemic. The hypotheses were evaluated in an online cross-sectional survey of 1286 parents. Latent profile analysis identified two profiles of received social support (isolated and integrated support). Three convergent profiles (high, moderate, and low support) and one divergent profile were found in perceived social support. The results revealed that the distribution of age, region, income...

Light propagation in gradient media and curved spaces induce intriguing phenomena, such as focusing and self-imaging, thus deriving a wide range of applications. However, these systems are limited to excitations without orbital angular momentum, which may obliterate unforeseen results. Here, we demonstrate the reconstructions (or called imaging to some extent) of optical vortices in two dimensional (2D) gradient media and three-dimensional (3D) curved spaces. We present the evolution of optical vortices in two types of...

Light propagation in gradient media and curved spaces induce intriguing phenomena, such as focusing and self-imaging, thus deriving a wide range of applications. However, these systems are limited to excitations without orbital angular momentum, which may obliterate unforeseen results. Here, we demonstrate the reconstructions (or called imaging to some extent) of optical vortices in two dimensional (2D) gradient media and three-dimensional (3D) curved spaces. We present the evolution of optical vortices in two types of...

The United Nations International Children’s Emergency Fund (UNICEF) initiatives of Child-Friendly Cities have operated in more than 3000 cities around the world. However, the concept of making the city child-friendly has not been extensively recognized in China. This article aims to report a regeneration project in a migrant workers’ community, the Mingdong, and is used to illustrate the reactions of residents to youth participation (youth civic engagement) and the project through an international workshop. The...

Early identification and intervention of cognitive decline could be effective to prevent progression to dementia. We developed a self-delivered cognitive screening tool, Automated Memory and Executive Screening (AMES), to assess cognitive domains including memory, language, and executive function. 189 participants with diagnoses of mild cognitive impairment (MCI, n = 43), subjective cognitive decline (SCD, n = 29), objectively-defined subtle cognitive decline (obj-SCD, n = 18), and normal controls (NC, n = 99) completed the study....

Optical pulling is an attractive concept due to the counterintuitive feature, the profound mechanism underneath and promising applications. In recent ten years, optical pulling of micro-nano objects have been fully demonstrated. However, optical pulling of a macroscopic object is challenging. Herein, laser pulling of a macroscopic object is presented in rarefied gas. The pulling force is originated from the Kundsen force when a gauss laser beam irradiates a macroscopic structure composed of the absorptive bulk...

Optical pulling is an attractive concept due to the counterintuitive feature, the profound mechanism underneath and promising applications. In recent ten years, optical pulling of micro-nano objects have been fully demonstrated. However, optical pulling of a macroscopic object is challenging. Herein, laser pulling of a macroscopic object is presented in rarefied gas. The pulling force is originated from the Kundsen force when a gauss laser beam irradiates a macroscopic structure composed of the absorptive bulk...

ObjectFocus on immune-related gene pairs (IRGPs) and develop a prognostic model to predict the prognosis of patients with lung adenocarcinoma (LUAD).MethodsFirst, the LUAD patient dataset was downloaded from The Cancer Genome Atlas database, and paired analysis of immune-related genes was subsequently conducted. Then, LASSO regression was used to screen prognostic IRGPs for building a risk prediction model. Meanwhile, the Gene Expression Omnibus database was used for external validation of the model. Next, the clinical predictive...

ObjectFocus on immune-related gene pairs (IRGPs) and develop a prognostic model to predict the prognosis of patients with lung adenocarcinoma (LUAD).MethodsFirst, the LUAD patient dataset was downloaded from The Cancer Genome Atlas database, and paired analysis of immune-related genes was subsequently conducted. Then, LASSO regression was used to screen prognostic IRGPs for building a risk prediction model. Meanwhile, the Gene Expression Omnibus database was used for external validation of the model. Next, the clinical predictive...

As an interesting phenomenon in the field of surface enhanced Raman spectroscopy (SERS), the plasmon-driven catalytic reaction (PDSC) induced by plasmonic hot electrons has great value in the research of novel properties of surface plasmons and accuracy of SERS applications. In this work, a optoplasmonic sandwich hybrid structure is proposed for studying PDSC of PATP mol-ecules , which is composed of Au film, metal organic frameworks (MOFs) nanoparticles (ZIF-8) and single SiO2 microsphere (Au film@MOFs@SiO2)....

Background:Acute liver failure (ALF) is a severe liver disease with high morbidity and mortality rates. Animal models are important for research on ALF. This study aimed to establish a reproducible, Tibetan miniature pig model of D-galactosamine-induced ALF and verify it using a dual plasma molecular adsorption system (DPMAS).Methods:Tibet miniature pigs were randomly divided into four groups (A, B, C, D) after catheterization. D-galactosamine (D-gal) at 0.45, 0.40, 0.35, and 0.35 g/kg body weight, respectively, was...

Recently, the concept of core-anti-resonant reflection (CARR) has been proposed, greatly expanding the options on cladding materials and morphologies for Fabry-Perot-type (F-P) cavities. For instance, a single-layer tube made of A4 paper can be a precision resonator in terahertz (THz) band, which seemed counterintuitive before. More importantly, thanks to the involvement of paper-like materials as the cavity plates, it is possible to equip the CARR cavity with the currently popular origami functionality. Following this clue,...

Optical waveguide amplifiers are essential devices in integrated optical systems. Their gain bandwidths directly determine the operating wavelength of optical circuits. Due to the difficulty of developing wideband gain media, it has been a challenge to fabricate devices with broadband amplification capability, resulting in few reports on multi-band polymer waveguide amplifiers. Here, a polymer waveguide amplifier is demonstrated, which achieves loss compensation covering the whole (S+C)-band by using NaYF4:Tm,Yb@NaYF4@NaYF4:Er nanoparticles-doped SU-8 as the gain medium....

In this paper, 2D and 3D Plasma Photonic Crystals (PPCs) were constructed using argon-mercury glow discharge tubes. Firstly, the collisional radiative model (CRM) was established for the glow discharge process, the average electron density of plasma in the discharge tube was calculated, and the average electron density was experimentally diagnosed by microwave diagnosis. By comparing the calculated and experimental results, the variation range of the average electron density in the tube was given. Secondly, according...

Objective quantification of photoreceptor cell morphology, such as cell diameter and outer segment length, is crucial for early, accurate, and sensitive diagnosis and prognosis of retinal neurodegenerative diseases. Adaptive optics optical coherence tomography (AO-OCT) provides three-dimensional (3-D) visualization of photoreceptor cells in the living human eye. The current gold standard for extracting cell morphology from AO-OCT images involves the tedious process of 2-D manual marking. To automate this process and extend to 3-D analysis of...

Bright γ-ray sources are of great significance for fundamental research, medicine and industry. However, γ-ray production by bremsstrahlung, Compton scattering, and synchrotron radiation is often subjected to large divergence, wide size and/or low efficiency, making it difficult to achieve high-brightness γ-ray sources. Here we have found an efficient mechanism to generate γ-rays with unprecedented brilliance by use of an ultrarelativistic electron beam with nC charge incident onto a solid surface at grazing incidence. With this...

Bright γ-ray sources are of great significance for fundamental research, medicine and industry. However, γ-ray production by bremsstrahlung, Compton scattering, and synchrotron radiation is often subjected to large divergence, wide size and/or low efficiency, making it difficult to achieve high-brightness γ-ray sources. Here we have found an efficient mechanism to generate γ-rays with unprecedented brilliance by use of an ultrarelativistic electron beam with nC charge incident onto a solid surface at grazing incidence. With this...

Introduction:Brain metastasis (BM) is a significant risk factor for survival and prognosis in non-small cell lung cancer (NSCLC). While surgical resection and radiotherapy are the primary treatment modalities, the overall prognosis in NSCLC patients with BM remains poor, and all therapies lead to adverse events. East Asian herbal medicine (EAHM) has broad prospects as an adjuvant treatment, but its efficacy and safety remain controversial. We propose to conduct a systematic review and meta-analysis to summarize...