17 Works

Recommendations for the treatment of rheumatoid arthritis in Saudi Arabia: adolopment of the 2021 American College of Rheumatology guidelines

Mohammed A. Omair, Hanan Al Rayes, Joanne Khabsa, Sally Yaacoub, Sultana Abdulaziz, Ghada A. Al Janobi, Abdulaziz Al Khalaf, Bader Al Mehmadi, Mahasin Al Nassar, Faisal AlBalawi, Abdullah S. AlFurayj, Ahmed Hamdan Al-Jedai, Haya Mohammed Almalag, Hajer Yousef Almudaiheem, Ali AlRehaily, Mohammed A. Attar, Lina El Kibbi, Hussein Halabi, Manal Hasan, Jasvinder A. Singh, Liana Fraenkel & Elie A. Akl
Abstract Background The 2021 American College of Rheumatology (ACR) rheumatoid arthritis (RA) guideline considers the specific context of the United States which differs from that of Saudi Arabia in many aspects that may impact recommendations. The objective of this project was to adapt a set of prioritized recommendations from the 2021 ACR guideline for the treatment of rheumatoid arthritis RA for the context of Saudi Arabia, by the Saudi Society for Rheumatology (SSR). Methods The...

An investigation of codon usage pattern analysis in pancreatitis associated genes

Yuanyang Li, Rekha Khandia, Marios Papadakis, Athanasios Alexiou, Alexander Nikolaevich Simonov & Azmat Ali Khan
Abstract Background Pancreatitis is an inflammatory disorder resulting from the autoactivation of trypsinogen in the pancreas. The genetic basis of the disease is an old phenomenon, and evidence is accumulating for the involvement of synonymous/non-synonymous codon variants in disease initiation and progression. Results The present study envisaged a panel of 26 genes involved in pancreatitis for their codon choices, compositional analysis, relative dinucleotide frequency, nucleotide disproportion, protein physical properties, gene expression, codon bias, and interrelated...

Biosynthesized silver nanoparticles and miR34a mimics mediated activation of death receptor in MCF-7 human breast cancer cell lines

Muhammad Javed Iqbal, Umer Rashid, Zeeshan Javed, Zara Hamid, Komal Imran, Ayesha Kabeer, Shahid Raza, Zainab M. Almarhoon, Željko Reiner, Iulia-Cristina Bagiu, Radu Vasile Bagiu, Ioan Sarac, Javad Sharifi-Rad, Alibek Ydyrys, Sevgi Durna Daştan, Monica Butnariu & William C. Cho
Abstract Nano-biotechnology-based clinical applications to cure health-related issues have gained huge attention among the scientific community and hold great promise to limit cancer metastasis. In this study, green-derived silver nanoparticles were synthesized by using leaf extract of Litchi chinensis. Characterization of biosynthesized silver nanoparticles was performed by using UV–Vis spectroscopy, FTIR, XRD, EDS, and SEM analysis. The clinical application of green-drive nanoparticles was investigated by using MCF-7 cancer cell lines. MCF-7 breast cancer cell lines...

Recommendations for the treatment of rheumatoid arthritis in Saudi Arabia: adolopment of the 2021 American College of Rheumatology guidelines

Mohammed A. Omair, Hanan Al Rayes, Joanne Khabsa, Sally Yaacoub, Sultana Abdulaziz, Ghada A. Al Janobi, Abdulaziz Al Khalaf, Bader Al Mehmadi, Mahasin Al Nassar, Faisal AlBalawi, Abdullah S. AlFurayj, Ahmed Hamdan Al-Jedai, Haya Mohammed Almalag, Hajer Yousef Almudaiheem, Ali AlRehaily, Mohammed A. Attar, Lina El Kibbi, Hussein Halabi, Manal Hasan, Jasvinder A. Singh, Liana Fraenkel & Elie A. Akl
Abstract Background The 2021 American College of Rheumatology (ACR) rheumatoid arthritis (RA) guideline considers the specific context of the United States which differs from that of Saudi Arabia in many aspects that may impact recommendations. The objective of this project was to adapt a set of prioritized recommendations from the 2021 ACR guideline for the treatment of rheumatoid arthritis RA for the context of Saudi Arabia, by the Saudi Society for Rheumatology (SSR). Methods The...

An image processing and machine learning solution to automate Egyptian cotton lint grading

Oliver J Fisher, Ahmed Rady, Aly AA El-Banna, Nicholas J Watson & Haitham H Emaish
Egyptian cotton is one of the most important commodities for the Egyptian economy and is renowned globally for its quality, which is largely assessed and graded by manual inspection. This grading has several drawbacks, including significant labor requirements, low inspection efficiency, and influence from inspection conditions such as light and human subjectivity. This work proposes a low-cost solution to replace manual inspection with classification models to grade Egyptian cotton lint using images captured by a...

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Abstract Background Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular function and sperm quality modulation with cannabis in rats. Methodology Twenty-five male Wistar rats were randomly grouped into five: A, B, C, and D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90...

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Inemesit A. Udofia, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Abstract Background Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular function and sperm quality modulation with cannabis in rats. Methodology Twenty-five male Wistar rats were randomly grouped into five: A, B, C, and D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90...

Spatio-temporal forecasting of future volcanism at Harrat Khaybar, Saudi Arabia

Abdullah Alohali, Daniel Bertin, Shanaka de Silva, Shane Cronin, Robert Duncan, Saleh Qaysi & Mohammed R. Moufti
Abstract The 180,000 km2 of Arabian lava fields (“harrats” in Arabic) form one of the largest distributed basaltic provinces in the world. The most recent eruption in 1256 AD, on the outskirts of Medina, as well as shallow dike emplacement in 2009, ~ 200 km northeast of the city, suggest future volcanic threat to this area. Harrat Khaybar (~ 1.7 Ma to present) is one of the largest and most compositionally diverse Arabian lava fields;...

An image processing and machine learning solution to automate Egyptian cotton lint grading

Oliver J Fisher, Ahmed Rady, Aly AA El-Banna, Nicholas J Watson & Haitham H Emaish
Egyptian cotton is one of the most important commodities for the Egyptian economy and is renowned globally for its quality, which is largely assessed and graded by manual inspection. This grading has several drawbacks, including significant labor requirements, low inspection efficiency, and influence from inspection conditions such as light and human subjectivity. This work proposes a low-cost solution to replace manual inspection with classification models to grade Egyptian cotton lint using images captured by a...

Assessment of the ability, perception, and readiness of nurses to manage tracheostomy-related complications in Riyadh City: a cross-sectional study

Fahad Zarraq Alotaibi, Reema Alkhatabi, Lujain Allowaihiq, Hassan Alhazzani, Ghada Alshehri, Eman A. Hajr & Feras Alkholaiwi
Abstract Background Nursing staff play a key role in the bedside management of tracheostomized patients in both intensive care units and general floors. Effective provision of postoperative care to these patients by nurses is critical. This study aimed to assess the readiness of nursing staff to manage tracheostomy-related complications in Riyadh, Saudi Arabia. Methods This cross-sectional study enrolled 395 nurses in Riyadh, Saudi Arabia. A self-administered questionnaire developed by the authors was distributed to nurses...

Biosynthesized silver nanoparticles and miR34a mimics mediated activation of death receptor in MCF-7 human breast cancer cell lines

Muhammad Javed Iqbal, Umer Rashid, Zeeshan Javed, Zara Hamid, Komal Imran, Ayesha Kabeer, Shahid Raza, Zainab M. Almarhoon, Željko Reiner, Iulia-Cristina Bagiu, Radu Vasile Bagiu, Ioan Sarac, Javad Sharifi-Rad, Alibek Ydyrys, Sevgi Durna Daştan, Monica Butnariu & William C. Cho
Abstract Nano-biotechnology-based clinical applications to cure health-related issues have gained huge attention among the scientific community and hold great promise to limit cancer metastasis. In this study, green-derived silver nanoparticles were synthesized by using leaf extract of Litchi chinensis. Characterization of biosynthesized silver nanoparticles was performed by using UV–Vis spectroscopy, FTIR, XRD, EDS, and SEM analysis. The clinical application of green-drive nanoparticles was investigated by using MCF-7 cancer cell lines. MCF-7 breast cancer cell lines...

Assessment of the ability, perception, and readiness of nurses to manage tracheostomy-related complications in Riyadh City: a cross-sectional study

Fahad Zarraq Alotaibi, Reema Alkhatabi, Lujain Allowaihiq, Hassan Alhazzani, Ghada Alshehri, Eman A. Hajr & Feras Alkholaiwi
Abstract Background Nursing staff play a key role in the bedside management of tracheostomized patients in both intensive care units and general floors. Effective provision of postoperative care to these patients by nurses is critical. This study aimed to assess the readiness of nursing staff to manage tracheostomy-related complications in Riyadh, Saudi Arabia. Methods This cross-sectional study enrolled 395 nurses in Riyadh, Saudi Arabia. A self-administered questionnaire developed by the authors was distributed to nurses...

Emergence of equine influenza virus H3Nx Florida clade 2 in Arabian racehorses in Egypt

Basem Mohamed Ahmed, Mahmoud Mohamed Bayoumi, Mohamed Ali Farrag, Mahmoud Aly Elgamal, Janet Mary Daly & Haitham Mohamed Amer
Abstract Background Equine influenza is an important cause of respiratory disease in equids. The causative virus; EIV, is highly variable and can evolve by accumulation of mutations, particularly in the haemagglutinin (HA) gene. Currently, H3N8 is the sole subtype circulating worldwide with Florida clade 1 (FC1) is most prevalent in the Americas and FC2 in Asia and Europe. In Egypt, EIV was detected in two occasions: subtype H7N7 in 1989 and subtype H3N8 (FC1) in...

Emergence of equine influenza virus H3Nx Florida clade 2 in Arabian racehorses in Egypt

Basem Mohamed Ahmed, Mahmoud Mohamed Bayoumi, Mohamed Ali Farrag, Mahmoud Aly Elgamal, Janet Mary Daly & Haitham Mohamed Amer
Abstract Background Equine influenza is an important cause of respiratory disease in equids. The causative virus; EIV, is highly variable and can evolve by accumulation of mutations, particularly in the haemagglutinin (HA) gene. Currently, H3N8 is the sole subtype circulating worldwide with Florida clade 1 (FC1) is most prevalent in the Americas and FC2 in Asia and Europe. In Egypt, EIV was detected in two occasions: subtype H7N7 in 1989 and subtype H3N8 (FC1) in...

Spatio-temporal forecasting of future volcanism at Harrat Khaybar, Saudi Arabia

Abdullah Alohali, Daniel Bertin, Shanaka de Silva, Shane Cronin, Robert Duncan, Saleh Qaysi & Mohammed R. Moufti
Abstract The 180,000 km2 of Arabian lava fields (“harrats” in Arabic) form one of the largest distributed basaltic provinces in the world. The most recent eruption in 1256 AD, on the outskirts of Medina, as well as shallow dike emplacement in 2009, ~ 200 km northeast of the city, suggest future volcanic threat to this area. Harrat Khaybar (~ 1.7 Ma to present) is one of the largest and most compositionally diverse Arabian lava fields;...

An investigation of codon usage pattern analysis in pancreatitis associated genes

Yuanyang Li, Rekha Khandia, Marios Papadakis, Athanasios Alexiou, Alexander Nikolaevich Simonov & Azmat Ali Khan
Abstract Background Pancreatitis is an inflammatory disorder resulting from the autoactivation of trypsinogen in the pancreas. The genetic basis of the disease is an old phenomenon, and evidence is accumulating for the involvement of synonymous/non-synonymous codon variants in disease initiation and progression. Results The present study envisaged a panel of 26 genes involved in pancreatitis for their codon choices, compositional analysis, relative dinucleotide frequency, nucleotide disproportion, protein physical properties, gene expression, codon bias, and interrelated...

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats

Charles O. Nwonuma, Victoria C. Nwatu, Gomaa Mostafa-Hedeab, Oluyomi S. Adeyemi, Omokolade O. Alejolowo, Oluwafemi Adeleke Ojo, Sylvanus A. Adah, Oluwakemi J. Awakan, Charles E. Okolie, Nnaemeka Tobechukwu Asogwa, Udofia A. Inemesit, Godshelp O. Egharevba, Nada H. Aljarba, Saad Alkahtani & Gaber El-Saber Batiha
Abstract Background Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular function and sperm quality modulation with cannabis in rats. Methodology Twenty-five male Wistar rats were randomly grouped into five: A, B, C, and D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90...

Registration Year

  • 2022
    17

Resource Types

  • Collection
    17

Affiliations

  • King Saud University
    17
  • Bowen University
    3
  • Elizade University
    3
  • Al Jouf University
    3
  • University of Ilorin
    3
  • Damanhour University
    3
  • Landmark University
    3
  • Princess Nourah bint Abdulrahman University
    3
  • Beni-Suef University
    3
  • University of Lagos
    3