14 Works

Perceived barriers to physical activity behaviour among patients with diabetes and hypertension in Kosovo: a qualitative study

Ariana Bytyci Katanolli, Nicole Probst-Hensch, Katrina Ann Obas, Jana Gerold, Manfred Zahorka, Naim Jerliu, Qamile Ramadani, Nicu Fota & Sonja Merten
Abstract Background In a cohort of primary health care users across Kosovo (KOSCO cohort), high rates and poor control of diabetes and hypertension were observed. These conditions can be prevented and better controlled by adapting to a healthy lifestyle. Physical activity is an important target, as inactivity and related obesity were very prevalent in the KOSCO cohort. This qualitative study aims to identify individual and structural barriers to physical activity perceived by patients with diabetes...

Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study

Manuel W. Hetzel, Jean Okitawutshu, Antoinette Tshefu, Elizabeth Omoluabi, Phyllis Awor, Aita Signorell, Nina C. Brunner, Jean-Claude Kalenga, Babatunde K. Akano, Kazeem Ayodeji, Charles Okon, Ocheche Yusuf, Proscovia Athieno, Joseph Kimera, Gloria Tumukunde, Irene Angiro, Giulia Delvento, Tristan T. Lee, Mark J. Lambiris, Marek Kwiatkowski, Nadja Cereghetti, Theodoor Visser, Harriet G. Napier, Justin M. Cohen, Valentina Buj … & Christian Lengeler
Abstract Background To prevent child deaths from severe malaria, early parenteral treatment is essential. Yet, in remote rural areas, accessing facilities offering parenteral antimalarials may be difficult. A randomised controlled trial found pre-referral treatment with rectal artesunate (RAS) to reduce deaths and disability in children who arrived at a referral facility with delay. This study examined the effectiveness of pre-referral RAS treatment implemented through routine procedures of established community-based health care systems. Methods An observational...

Dietary diversity in primary schoolchildren of south-central Côte d’Ivoire and risk factors for non-communicable diseases

Sylvain G. Traoré, Kouadio B. Kouassi, Jean T. Coulibaly, Johanna Beckmann, Bomey C. Gba, Christin Lang, Kurt Z. Long, Daouda Dao, Markus Gerber, Nicole Probst-Hensch, Uwe Pühse, Jürg Utzinger & Bassirou Bonfoh
Abstract Background A balanced nutrition is important for children’s physical and cognitive development; yet, remains a challenge in many parts of low- and middle-income countries (LMICs). Early detection of nutritional deficiency and metabolic syndrome in school-aged children is necessary to prevent non-communicable diseases (NCDs) in later life. This study aimed at obtaining baseline data on health, nutritional status, and metabolic markers of NCDs among primary schoolchildren in Côte d’Ivoire. Methods A cross-sectional survey was conducted...

Patient variability in the blood-stage dynamics of Plasmodium falciparum captured by clustering historical data

Thiery Masserey, Melissa A. Penny & Tamsin E. Lee
Abstract Background Mathematical models provide an understanding of the dynamics of a Plasmodium falciparum blood-stage infection (within-host models), and can predict the impact of control strategies that affect the blood-stage of malaria. However, the dynamics of P. falciparum blood-stage infections are highly variable between individuals. Within-host models use different techniques to capture this inter-individual variation. This struggle may be unnecessary because patients can be clustered according to similar key within-host dynamics. This study aimed to...

Health care providers’ knowledge of clinical protocols for postpartum hemorrhage care in Kenya: a cross-sectional study

Junita Henry, Emma Clarke-Deelder, Dan Han, Nora Miller, Kennedy Opondo, Monica Oguttu, Thomas Burke, Jessica L. Cohen & Margaret McConnell
Abstract Background Postpartum hemorrhage (PPH) remains the leading cause of maternal death worldwide despite its often-preventable nature. Understanding health care providers’ knowledge of clinical protocols is imperative for improving quality of care and reducing mortality. This is especially pertinent in referral and teaching hospitals that train nursing and medical students and interns in addition to managing emergency and referral cases. Methods This study aimed to (1) measure health care providers’ knowledge of clinical protocols for...

Detection of Salmonella Typhi nucleic acid by RT-PCR and anti-HlyE, -CdtB, -PilL, and -Vi IgM by ELISA at sites in Ghana, Madagascar and Ethiopia

Ursula Panzner, Ondari Daniel Mogeni, Yaw Adu-Sarkodie, Trevor Toy, Hyon Jin Jeon, Gi Deok Pak, Se Eun Park, Yeetey Enuameh, Ellis Owusu-Dabo, Trinh Van Tan, Abraham Aseffa, Mekonnen Teferi, Biruk Yeshitela, Stephen Baker, Raphael Rakotozandrindrainy & Florian Marks
Abstract Background We aimed to assess the prevalence of Salmonella Typhi through DNA and IgM-antibody detection methods as a prelude to extended surveillance activities at sites in Ghana, Madagascar, and Ethiopia. Methods We performed species-specific real-time polymerase reaction (RT-PCR) to identify bacterial nucleic acid, and enzyme-linked immunosorbent assay (ELISA) for detecting HlyE/STY1498-, CdtB/STY1886-, pilL/STY4539- and Vi-antigens in blood and biopsy specimens of febrile and non-febrile subjects. We generated antigen-specific ELISA proxy cut-offs by change-point analyses,...

Detection of Salmonella Typhi nucleic acid by RT-PCR and anti-HlyE, -CdtB, -PilL, and -Vi IgM by ELISA at sites in Ghana, Madagascar and Ethiopia

Ursula Panzner, Ondari Daniel Mogeni, Yaw Adu-Sarkodie, Trevor Toy, Hyon Jin Jeon, Gi Deok Pak, Se Eun Park, Yeetey Enuameh, Ellis Owusu-Dabo, Trinh Van Tan, Abraham Aseffa, Mekonnen Teferi, Biruk Yeshitela, Stephen Baker, Raphael Rakotozandrindrainy & Florian Marks
Abstract Background We aimed to assess the prevalence of Salmonella Typhi through DNA and IgM-antibody detection methods as a prelude to extended surveillance activities at sites in Ghana, Madagascar, and Ethiopia. Methods We performed species-specific real-time polymerase reaction (RT-PCR) to identify bacterial nucleic acid, and enzyme-linked immunosorbent assay (ELISA) for detecting HlyE/STY1498-, CdtB/STY1886-, pilL/STY4539- and Vi-antigens in blood and biopsy specimens of febrile and non-febrile subjects. We generated antigen-specific ELISA proxy cut-offs by change-point analyses,...

Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study

Manuel W. Hetzel, Jean Okitawutshu, Antoinette Tshefu, Elizabeth Omoluabi, Phyllis Awor, Aita Signorell, Nina C. Brunner, Jean-Claude Kalenga, Babatunde K. Akano, Kazeem Ayodeji, Charles Okon, Ocheche Yusuf, Proscovia Athieno, Joseph Kimera, Gloria Tumukunde, Irene Angiro, Giulia Delvento, Tristan T. Lee, Mark J. Lambiris, Marek Kwiatkowski, Nadja Cereghetti, Theodoor Visser, Harriet G. Napier, Justin M. Cohen, Valentina Buj … & Christian Lengeler
Abstract Background To prevent child deaths from severe malaria, early parenteral treatment is essential. Yet, in remote rural areas, accessing facilities offering parenteral antimalarials may be difficult. A randomised controlled trial found pre-referral treatment with rectal artesunate (RAS) to reduce deaths and disability in children who arrived at a referral facility with delay. This study examined the effectiveness of pre-referral RAS treatment implemented through routine procedures of established community-based health care systems. Methods An observational...

Patient variability in the blood-stage dynamics of Plasmodium falciparum captured by clustering historical data

Thiery Masserey, Melissa A. Penny & Tamsin E. Lee
Abstract Background Mathematical models provide an understanding of the dynamics of a Plasmodium falciparum blood-stage infection (within-host models), and can predict the impact of control strategies that affect the blood-stage of malaria. However, the dynamics of P. falciparum blood-stage infections are highly variable between individuals. Within-host models use different techniques to capture this inter-individual variation. This struggle may be unnecessary because patients can be clustered according to similar key within-host dynamics. This study aimed to...

Health care providers’ knowledge of clinical protocols for postpartum hemorrhage care in Kenya: a cross-sectional study

Junita Henry, Emma Clarke-Deelder, Dan Han, Nora Miller, Kennedy Opondo, Monica Oguttu, Thomas Burke, Jessica L. Cohen & Margaret McConnell
Abstract Background Postpartum hemorrhage (PPH) remains the leading cause of maternal death worldwide despite its often-preventable nature. Understanding health care providers’ knowledge of clinical protocols is imperative for improving quality of care and reducing mortality. This is especially pertinent in referral and teaching hospitals that train nursing and medical students and interns in addition to managing emergency and referral cases. Methods This study aimed to (1) measure health care providers’ knowledge of clinical protocols for...

The use of routine health facility data for micro-stratification of malaria risk in mainland Tanzania

Sumaiyya G. Thawer, Monica Golumbeanu, Khalifa Munisi, Sijenunu Aaron, Frank Chacky, Samwel Lazaro, Ally Mohamed, Noela Kisoka, Christian Lengeler, Fabrizio Molteni, Amanda Ross, Robert W. Snow & Emilie Pothin
Abstract Background Current efforts to estimate the spatially diverse malaria burden in malaria-endemic countries largely involve the use of epidemiological modelling methods for describing temporal and spatial heterogeneity using sparse interpolated prevalence data from periodic cross-sectional surveys. However, more malaria-endemic countries are beginning to consider local routine data for this purpose. Nevertheless, routine information from health facilities (HFs) remains widely under-utilized despite improved data quality, including increased access to diagnostic testing and the adoption of...

The use of routine health facility data for micro-stratification of malaria risk in mainland Tanzania

Sumaiyya G. Thawer, Monica Golumbeanu, Khalifa Munisi, Sijenunu Aaron, Frank Chacky, Samwel Lazaro, Ally Mohamed, Noela Kisoka, Christian Lengeler, Fabrizio Molteni, Amanda Ross, Robert W. Snow & Emilie Pothin
Abstract Background Current efforts to estimate the spatially diverse malaria burden in malaria-endemic countries largely involve the use of epidemiological modelling methods for describing temporal and spatial heterogeneity using sparse interpolated prevalence data from periodic cross-sectional surveys. However, more malaria-endemic countries are beginning to consider local routine data for this purpose. Nevertheless, routine information from health facilities (HFs) remains widely under-utilized despite improved data quality, including increased access to diagnostic testing and the adoption of...

Perceived barriers to physical activity behaviour among patients with diabetes and hypertension in Kosovo: a qualitative study

Ariana Bytyci Katanolli, Nicole Probst-Hensch, Katrina Ann Obas, Jana Gerold, Manfred Zahorka, Naim Jerliu, Qamile Ramadani, Nicu Fota & Sonja Merten
Abstract Background In a cohort of primary health care users across Kosovo (KOSCO cohort), high rates and poor control of diabetes and hypertension were observed. These conditions can be prevented and better controlled by adapting to a healthy lifestyle. Physical activity is an important target, as inactivity and related obesity were very prevalent in the KOSCO cohort. This qualitative study aims to identify individual and structural barriers to physical activity perceived by patients with diabetes...

Dietary diversity in primary schoolchildren of south-central Côte d’Ivoire and risk factors for non-communicable diseases

Sylvain G. Traoré, Kouadio B. Kouassi, Jean T. Coulibaly, Johanna Beckmann, Bomey C. Gba, Christin Lang, Kurt Z. Long, Daouda Dao, Markus Gerber, Nicole Probst-Hensch, Uwe Pühse, Jürg Utzinger & Bassirou Bonfoh
Abstract Background A balanced nutrition is important for children’s physical and cognitive development; yet, remains a challenge in many parts of low- and middle-income countries (LMICs). Early detection of nutritional deficiency and metabolic syndrome in school-aged children is necessary to prevent non-communicable diseases (NCDs) in later life. This study aimed at obtaining baseline data on health, nutritional status, and metabolic markers of NCDs among primary schoolchildren in Côte d’Ivoire. Methods A cross-sectional survey was conducted...

Registration Year

  • 2022
    14

Resource Types

  • Collection
    14

Affiliations

  • University of Basel
    14
  • Swiss Tropical and Public Health Institute
    14
  • Clinton Health Access Initiative
    4
  • Massachusetts General Hospital
    2
  • Kwame Nkrumah University of Science and Technology
    2
  • Huazhong University of Science and Technology
    2
  • Kangbuk Samsung Hospital
    2
  • University of Cambridge
    2
  • Federal Ministry of Health
    2
  • World Health Organization
    2