8 Works

A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes

Huishi Toh, Chentao Yang, Giulio Formenti, Kalpana Raja, Lily Yan, Alan Tracey, William Chow, Kerstin Howe, Lucie A. Bergeron, Guojie Zhang, Bettina Haase, Jacquelyn Mountcastle, Olivier Fedrigo, John Fogg, Bogdan Kirilenko, Chetan Munegowda, Michael Hiller, Aashish Jain, Daisuke Kihara, Arang Rhie, Adam M. Phillippy, Scott A. Swanson, Peng Jiang, Dennis O. Clegg, Erich D. Jarvis … & Yury V. Bukhman
Abstract Background The Nile rat (Avicanthis niloticus) is an important animal model because of its robust diurnal rhythm, a cone-rich retina, and a propensity to develop diet-induced diabetes without chemical or genetic modifications. A closer similarity to humans in these aspects, compared to the widely used Mus musculus and Rattus norvegicus models, holds the promise of better translation of research findings to the clinic. Results We report a 2.5 Gb, chromosome-level reference genome assembly with...

Psychometric Properties of the Self-Injurious Thoughts and Behaviors Interview–Short Form Among U.S. Active Duty Military Service Members and Veterans

Ian H. Stanley, Brian P. Marx, Brooke A. Fina, Stacey Young-McCaughan, Hannah C. Tyler, Denise M. Sloan, Abby E. Blankenship, Katherine A. Dondanville, James L. Walker, Joseph W. Boffa, Craig J. Bryan, Lily A. Brown, Casey L. Straud, Jim Mintz, Chadi G. Abdallah, Sudie E. Back, Tabatha H. Blount, Bryann B. DeBeer, Julianne Flanagan, Edna B. Foa, Peter T. Fox, Steffany J. Fredman, John Krystal, Meghan E. McDevitt-Murphy, Donald D. McGeary … & Alan L. Peterson
We assessed the interrater reliability, convergent validity, and discriminant validity of the Self-Injurious Thoughts and Behaviors Interview-Short Form (SITBI-SF) in a sample of 1,944 active duty service members and veterans seeking services for posttraumatic stress disorder (PTSD) and related conditions. The SITBI-SF demonstrated high interrater reliability and good convergent and discriminant validity. The measurement properties of the SITBI-SF were comparable across service members and veterans. Approximately 8% of participants who denied a history of suicidal...

Psychometric Properties of the Self-Injurious Thoughts and Behaviors Interview–Short Form Among U.S. Active Duty Military Service Members and Veterans

Ian H. Stanley, Brian P. Marx, Brooke A. Fina, Stacey Young-McCaughan, Hannah C. Tyler, Denise M. Sloan, Abby E. Blankenship, Katherine A. Dondanville, James L. Walker, Joseph W. Boffa, Craig J. Bryan, Lily A. Brown, Casey L. Straud, Jim Mintz, Chadi G. Abdallah, Sudie E. Back, Tabatha H. Blount, Bryann B. DeBeer, Julianne Flanagan, Edna B. Foa, Peter T. Fox, Steffany J. Fredman, John Krystal, Meghan E. McDevitt-Murphy, Donald D. McGeary … & Alan L. Peterson
We assessed the interrater reliability, convergent validity, and discriminant validity of the Self-Injurious Thoughts and Behaviors Interview-Short Form (SITBI-SF) in a sample of 1,944 active duty service members and veterans seeking services for posttraumatic stress disorder (PTSD) and related conditions. The SITBI-SF demonstrated high interrater reliability and good convergent and discriminant validity. The measurement properties of the SITBI-SF were comparable across service members and veterans. Approximately 8% of participants who denied a history of suicidal...

Teaching Trauma Content in Higher Education: A Systematic Literature Review

Jessica Gladden, Bridget E. Weller, Adrian Hernandez & Andrea Hopkins
Higher education must prepare future mental health providers to work with individuals who have been exposed to trauma. This is vital to the success of students’ practice, many of whom would benefit from trauma reduction strategies in their own lives. The purpose of this systematic review is to summarize the knowledge base on teaching methods that may reduce the potential that trauma content in the classroom could cause: (a) re-traumatization; (b) vicarious traumatization; or (c)...

Estimating the optimal linear combination of predictors using spherically constrained optimization

Priyam Das, Debsurya De, Raju Maiti, Mona Kamal, Katherine A. Hutcheson, Clifton D. Fuller, Bibhas Chakraborty & Christine B. Peterson
Abstract Background In the context of a binary classification problem, the optimal linear combination of continuous predictors can be estimated by maximizing the area under the receiver operating characteristic curve. For ordinal responses, the optimal predictor combination can similarly be obtained by maximization of the hypervolume under the manifold (HUM). Since the empirical HUM is discontinuous, non-differentiable, and possibly multi-modal, solving this maximization problem requires a global optimization technique. Estimation of the optimal coefficient vector...

Estimating the optimal linear combination of predictors using spherically constrained optimization

Priyam Das, Debsurya De, Raju Maiti, Mona Kamal, Katherine A. Hutcheson, Clifton D. Fuller, Bibhas Chakraborty & Christine B. Peterson
Abstract Background In the context of a binary classification problem, the optimal linear combination of continuous predictors can be estimated by maximizing the area under the receiver operating characteristic curve. For ordinal responses, the optimal predictor combination can similarly be obtained by maximization of the hypervolume under the manifold (HUM). Since the empirical HUM is discontinuous, non-differentiable, and possibly multi-modal, solving this maximization problem requires a global optimization technique. Estimation of the optimal coefficient vector...

A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes

Huishi Toh, Chentao Yang, Giulio Formenti, Kalpana Raja, Lily Yan, Alan Tracey, William Chow, Kerstin Howe, Lucie A. Bergeron, Guojie Zhang, Bettina Haase, Jacquelyn Mountcastle, Olivier Fedrigo, John Fogg, Bogdan Kirilenko, Chetan Munegowda, Michael Hiller, Aashish Jain, Daisuke Kihara, Arang Rhie, Adam M. Phillippy, Scott A. Swanson, Peng Jiang, Dennis O. Clegg, Erich D. Jarvis … & Yury V. Bukhman
Abstract Background The Nile rat (Avicanthis niloticus) is an important animal model because of its robust diurnal rhythm, a cone-rich retina, and a propensity to develop diet-induced diabetes without chemical or genetic modifications. A closer similarity to humans in these aspects, compared to the widely used Mus musculus and Rattus norvegicus models, holds the promise of better translation of research findings to the clinic. Results We report a 2.5 Gb, chromosome-level reference genome assembly with...

Teaching Trauma Content in Higher Education: A Systematic Literature Review

Jessica Gladden, Bridget E. Weller, Adrian Hernandez & Andrea Hopkins
Higher education must prepare future mental health providers to work with individuals who have been exposed to trauma. This is vital to the success of students’ practice, many of whom would benefit from trauma reduction strategies in their own lives. The purpose of this systematic review is to summarize the knowledge base on teaching methods that may reduce the potential that trauma content in the classroom could cause: (a) re-traumatization; (b) vicarious traumatization; or (c)...

Registration Year

  • 2023
    2
  • 2022
    6

Resource Types

  • Collection
    8

Affiliations

  • Duke Medical Center
    8
  • Duke University
    4
  • Cleveland State University
    2
  • Howard Hughes Medical Institute
    2
  • National Human Genome Research Institute
    2
  • Indian Statistical Institute
    2
  • Senckenberg Society for Nature Research
    2
  • Chongqing Medical University
    2
  • The University of Texas at San Antonio
    2
  • National University of Singapore
    2