3 Works

Humor no ensino da Matemática: tarefas para a sala de aula

Luís Menezes, Helena Gomes, António Ribeiro, Ana Patrícia Martins, Pablo Flores, Floriano Viseu, Ana Maria Oliveira, Isabel Aires Matos, João Paulo Balula & Véronique Delplancq

H3K18 lactylation marks tissue-specific active enhancers

Eva Galle, Chee-Wai Wong, Adhideb Ghosh, Thibaut Desgeorges, Kate Melrose, Laura C. Hinte, Daniel Castellano-Castillo, Magdalena Engl, Joao Agostinho de Sousa, Francisco Javier Ruiz-Ojeda, Katrien De Bock, Jonatan R. Ruiz & Ferdinand von Meyenn
Abstract Background Histone lactylation has been recently described as a novel histone post-translational modification linking cellular metabolism to epigenetic regulation. Results Given the expected relevance of this modification and current limited knowledge of its function, we generate genome-wide datasets of H3K18la distribution in various in vitro and in vivo samples, including mouse embryonic stem cells, macrophages, adipocytes, and mouse and human skeletal muscle. We compare them to profiles of well-established histone modifications and gene expression...

H3K18 lactylation marks tissue-specific active enhancers

Eva Galle, Chee-Wai Wong, Adhideb Ghosh, Thibaut Desgeorges, Kate Melrose, Laura C. Hinte, Daniel Castellano-Castillo, Magdalena Engl, Joao Agostinho de Sousa, Francisco Javier Ruiz-Ojeda, Katrien De Bock, Jonatan R. Ruiz & Ferdinand von Meyenn
Abstract Background Histone lactylation has been recently described as a novel histone post-translational modification linking cellular metabolism to epigenetic regulation. Results Given the expected relevance of this modification and current limited knowledge of its function, we generate genome-wide datasets of H3K18la distribution in various in vitro and in vivo samples, including mouse embryonic stem cells, macrophages, adipocytes, and mouse and human skeletal muscle. We compare them to profiles of well-established histone modifications and gene expression...

Registration Year

  • 2022
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  • 2020
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Resource Types

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Affiliations

  • University of Granada
    3
  • Helmholtz Zentrum München
    2
  • ETH Zurich
    2
  • Polytechnic Institute of Viseu
    1
  • University of Minho
    1