8 Works

Supplementary material from \"Genomic evidence for ancient human migration routes along South America's Atlantic coast\"

Andre Luiz Campelo dos Santos, Amanda Owings, Henry Socrates Lavalle Sullasi, Omer Gokcumen, Michael DeGiorgio & John Lindo
An increasing body of archaeological and genomic evidence has hinted to a complex settlement process of the Americas by humans. This is especially true for South America, where unexpected ancestral signals have raised perplexing scenarios for the early migrations into different regions of the continent. Here, we present ancient human genomes from the archaeologically rich Northeast Brazil and compare them to ancient and present-day genomic data. We find a distinct relationship between ancient genomes from...

Convergence on reduced aggression through shared behavioral traits in multiple populations of Astyanax mexicanus

Roberto Rodriguez-Morales, Paola Gonzalez-Lerma, Anders Yuiska, Ji Heon Han, Yolanda Guerra, Lina Crisostomo, Alex C. Keene, Erik R. Duboue & Johanna E. Kowalko
Abstract Background Aggression is observed across the animal kingdom, and benefits animals in a number of ways to increase fitness and promote survival. While aggressive behaviors vary widely across populations and can evolve as an adaptation to a particular environment, the complexity of aggressive behaviors presents a challenge to studying the evolution of aggression. The Mexican tetra, Astyanax mexicanus exists as an aggressive river-dwelling surface form and multiple populations of a blind cave form, some...

Supplementary material from \"Genomic evidence for ancient human migration routes along South America's Atlantic coast\"

Andre Luiz Campelo dos Santos, Amanda Owings, Henry Socrates Lavalle Sullasi, Omer Gokcumen, Michael DeGiorgio & John Lindo
An increasing body of archaeological and genomic evidence has hinted to a complex settlement process of the Americas by humans. This is especially true for South America, where unexpected ancestral signals have raised perplexing scenarios for the early migrations into different regions of the continent. Here, we present ancient human genomes from the archaeologically rich Northeast Brazil and compare them to ancient and present-day genomic data. We find a distinct relationship between ancient genomes from...

Convergence on reduced aggression through shared behavioral traits in multiple populations of Astyanax mexicanus

Roberto Rodriguez-Morales, Paola Gonzalez-Lerma, Anders Yuiska, Ji Heon Han, Yolanda Guerra, Lina Crisostomo, Alex C. Keene, Erik R. Duboue & Johanna E. Kowalko
Abstract Background Aggression is observed across the animal kingdom, and benefits animals in a number of ways to increase fitness and promote survival. While aggressive behaviors vary widely across populations and can evolve as an adaptation to a particular environment, the complexity of aggressive behaviors presents a challenge to studying the evolution of aggression. The Mexican tetra, Astyanax mexicanus exists as an aggressive river-dwelling surface form and multiple populations of a blind cave form, some...

Barriers and Best Practices in Disclosing a Dementia Diagnosis: A Clinician Interview Study

Easton N Wollney, Melissa J Armstrong, Noheli Bedenfield, Monica Rosselli, Rosie E Curiel-Cid, Marcela Kitaigorodsky, Ximena Levy & Carma L Bylund
The vast majority of individuals with dementia want to receive a diagnosis. Research suggests, however, that only a fraction of individuals with dementia receive a diagnosis and patients and families often feel the information is poorly explained. We thus aimed to assess clinician-reported barriers to dementia disclosure and recommendations for giving a dementia diagnosis. To accomplish this, we performed telephone interviews with 15 clinicians from different specialties using a semi-structured interview guide. Transcripts were analyzed...

Barriers and Best Practices in Disclosing a Dementia Diagnosis: A Clinician Interview Study

Easton N Wollney, Melissa J Armstrong, Noheli Bedenfield, Monica Rosselli, Rosie E Curiel-Cid, Marcela Kitaigorodsky, Ximena Levy & Carma L Bylund
The vast majority of individuals with dementia want to receive a diagnosis. Research suggests, however, that only a fraction of individuals with dementia receive a diagnosis and patients and families often feel the information is poorly explained. We thus aimed to assess clinician-reported barriers to dementia disclosure and recommendations for giving a dementia diagnosis. To accomplish this, we performed telephone interviews with 15 clinicians from different specialties using a semi-structured interview guide. Transcripts were analyzed...

Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage

Qixing Li, Yanpeng Li, Bibo Liang, Rui Xu, Bingze Xu, Erik Lönnblom, Hui Feng, Jing’an Bai, Roma Stawikowska, Changrong Ge, Aiping Lu, Gregg B. Fields, Lianbo Xiao & Rikard Holmdahl
Abstract Objective To investigate the occurrence and frequency of anti-citrullinated protein antibodies (ACPA) to cyclic citrullinated type II collagen (COL2) epitope with a capacity to bind joint cartilage. Methods Luminex immunoassay was used to analyze serum antibody reactivity to 10 COL2-citrullinated peptides (ACC10) and corresponding arginine peptide controls in rheumatoid arthritis (RA), osteoarthritis (OA), and healthy individuals’ cohorts. Top ten “promiscuous” sera (cross-reactive with all ACC10) and top ten “private” sera (restrictedly reactive with one...

Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage

Qixing Li, Yanpeng Li, Bibo Liang, Rui Xu, Bingze Xu, Erik Lönnblom, Hui Feng, Jing’an Bai, Roma Stawikowska, Changrong Ge, Aiping Lu, Gregg B. Fields, Lianbo Xiao & Rikard Holmdahl
Abstract Objective To investigate the occurrence and frequency of anti-citrullinated protein antibodies (ACPA) to cyclic citrullinated type II collagen (COL2) epitope with a capacity to bind joint cartilage. Methods Luminex immunoassay was used to analyze serum antibody reactivity to 10 COL2-citrullinated peptides (ACC10) and corresponding arginine peptide controls in rheumatoid arthritis (RA), osteoarthritis (OA), and healthy individuals’ cohorts. Top ten “promiscuous” sera (cross-reactive with all ACC10) and top ten “private” sera (restrictedly reactive with one...

Registration Year

  • 2022
    8

Resource Types

  • Collection
    8

Affiliations

  • Florida Atlantic University
    8
  • Central South University
    2
  • Chengdu University of Traditional Chinese Medicine
    2
  • Second Affiliated Hospital of Chongqing Medical University
    2
  • Northwest University
    2
  • Lehigh University
    2
  • University of North Carolina at Chapel Hill
    2
  • Texas A&M University
    2
  • Ruijin Hospital
    2
  • Ministry of Education of the People's Republic of China
    2