2,046 Works

A new deletion allele of sma-4

Alexandra N. McKillop, Herong Shi & Jun Liu
sma-4 encodes the co-Smad of the BMP pathway in C. elegans, which is also known as the Sma/Mab pathway (Savage et al. 1996). Null mutations in core components of this pathway, including the BMP ligand DBL-1, the receptors SMA-6 and DAF-4, and the R-Smads SMA-2 and SMA-3, all result in a small body size phenotype without significantly compromising viability (Gumienny and Savage-Dunn 2013). However, we found that even after multiple rounds of out-crossing, two deletion...

Experimental and Theoretical Study on Screwed Connections in Cold-Formed Steel Structure

Rattanasak HONGTHONG, Apai BENCHAPHONG, Sutera BENCHANUKROM & Nirut KONKONG
This research aims to study the fastening rotation behavior of cold-formed steel screw connections by experimental testing and analytical modelling. Both the experimental test and finite element results showed the failure modes of tilting and bearing failure. The rotation failure mode of the screw connection was studied by an analytical method using a spring model with screw-plate stiffness which included the bending and shear stiffness of the screw and the bearing stiffness of the screw...

Construire avec des ressources locales : le béton de terre coulé

Sophie Nicot, Philippe Devillers & Éric Garcia Diaz
Alors qu’on utilisait la terre, la pierre ou encore le bois dans la construction depuis des millénaires, l’évolution des techniques de construction ainsi que la standardisation des matériaux et des bâtiments ont conduit à leur abandon progressif. L’utilisation de matériaux locaux peu transformés favorise le développement de pratiques architecturales plus écologiques en réduisant l’empreinte énergétique des ouvrages et en améliorant l’insertion des ouvrages dans le paysage. Le béton de terre coulé peut être comparé au...

A backup orientation system based on inverse problems technique

Aleksey V. NENAROKOMOV, Evgeny V. CHEBAKOV, Irina V. KRAINOVA, Dmitry L. REVIZNIKOV & Alena V. MORZHUKHINA

Modélisation de la durabilité des ouvrages béton : couplage carbonatation/chlorure

Lucie Schmitt
La maitrise et l’optimisation de la durabilité des structures en béton ainsi que la maintenance des ouvrages en béton existants constituent un enjeu important pour l’ensemble des acteurs de la profession. Un plan expérimental a été mis en place afin de caractériser les propriétés hydriques de quatre bétons ainsi que leur comportement vis-à-vis de la corrosion des armatures. Les propriétés discutées dans cet article sont la carbonatation et la désorption. Ces résultats vont conduire à...

Marcas Tecnológicas e Plataformas de Marca: a terceira era de Branding e a Plataformização

Herlander Elias & Júlio Ferreira

Mises en chiffres, mises en cartes, mises en ordre du monde

Matthieu Noucher, Irène Hirt & Xavier Arnauld de Sartre

Wpływ wybranych nawozów mikroelementowych firmy adob na plon i wartość browarną ziarna jęczmienia jarego

Marek Liszewski & Józef Błażewicz

Annotated checklist for fishes of the Main Nile Basin in the Sudan and Egypt based on recent specimen records (2006-2015)

Dirk Neumann, Henriette Obermaier & Timo Moritz
The results of several short ichthyological surveys on the Nile Basin in Sudan between 2006 and 2015 are presented. In attempting to represent major type localities and recently observed variability, we complement known field records with records of a reference collection of recent fish bones collected during the 1980s and records of aberrant cichlids populations in Egypt observed at El Fayum and in lakes of the Nile Delta. From 133 native species in the Republic...

The Dose, Episode 15: Health Care in America: How Doctors Can Make Life Easier for Patients

Shanoor Seervai

Anestetyka a ocenianie i kategoryzowanie sztuki

Bogusław Dziadzia

Putting a Price on Social Services: North Carolina’s Pilot Effort

Mandy Cohen, Elizabeth Cuervo Tilson, Melinda Dutton, Jocelyn Guyer, Melinda Abrams & Laurie Zephyrin

Beta maṣāḥǝft TEI-XML Data

Pietro Maria Liuzzo, Dorothea Reule & Gebreyes Beyene Solomon

Checklist of the marine fishes from metropolitan France

Philippe Béarez, Patrice Pruvost, Eric Feunteun, Samuel P. Iglésias, Patrice Francour, Romain Causse, Jeanne De Mazieres, Sandrine Tercerie & Nicolas Bailly
A list of the marine fish species occurring in the French EEZ was assembled from more than 200 references. No updated list has been published since the 19th century, although incomplete versions were available in several biodiversity information systems. The list contains 729 species distributed in 185 families. It is a preliminary step for the Atlas of Marine Fishes of France that will be further elaborated within the INPN (the National Inventory of the Natural...

A Tale of Two Systems: Primary Care Physicians in the U.S. and the Netherlands Reflect on Their Work

Noam N. Levey
Two Dutch primary care physicians chose to practice medicine in different countries. One worked in a medical office in the Netherlands; the other started a family practice near Seattle. A feature by Noam Levey of the Los Angeles Times examines their choices and vastly different feelings about medicine and health care.

Droplet bouncing on the surface with micro-structure

T. BOBINSKI, G. SOBIERAJ, M. PSARSKI, G. CELICHOWSKI & J. ROKICKI

Tools for Mos1-mediated single copy insertion (mosSCI) with excisable unc-119(+) or NeoR (G418) selection cassettes

Reta Aram, Kailynn MacGillivray, Chengyin Li & Arneet L Saltzman
Insertion of single-copy transgenes is an important tool in C. elegans genome engineering. Following the discovery that the Drosophila mariner element Mos1 could mobilize in the C. elegans germline (Bessereau et al. 2001), tools for efficient Mos1-mediated transgene insertion have been developed and widely adopted (Robert and Bessereau 2010). In parallel, the establishment of effective antibiotic selection in C. elegans offered increased versatility for genetic crosses and the advantage of injecting into phenotypically wild-type animals (Giordano-Santini et al. 2010, Semple et al. 2010). Reliable, site-specific, single-copy...

Using diffusivity and dissipation of electromagnetic waves in concrete as new non-destructive parameters for nuclear structures evaluation

Mehdi Sbartaï, Stephen Razafindratsima, Jean-Paul Balayssac, Cédric Payan, Sandrine Rakotonarivo & Vincent Garnier
Il est nécessaire d’utiliser les méthodes non-destructives pour une bonne évaluation des structures en béton. Dans ce cadre, plusieurs développements ont été effectués en Géoradar et la recherche de nouveaux observables autres que la vitesse de l’onde électromagnétique ou son atténuation, qui pourraient être plus sensibles à la dégradation du béton est d’une grande importance. Cet article présente l’analyse de la diffusion de l’onde électromagnétique dans le béton. Nous avons montré que la diffusivité D...

The Dose, Episode 14: ‘More Is Not Always Better’: One Campaign to Stop Overuse of Medical Care

Shanoor Seervai

First report of the yellowfin surgeonfish Acanthurus xanthopterus (Teleostei: Acanthuridae) in northern Peru

Sarita Campos-León, Andrey Moreno-Méndez, Philippe Béarez & Amado Solano-Sare
The yellowfin surgeonfish Acanthurus xanthopterus is distributed throughout the tropical Indo-Pacific Ocean and the eastern Pacific, from the coasts of Africa to the coasts of the Americas. In the eastern Pacific, it extends from the Gulf of California to Ecuador. Two specimens of yellowfin surgeonfish, caught in northern Peru in February 2019, are reported: the first from Puerto Morin (08°24’02”S; 78°54 03”W), and the second one from Puerto Salaverry (Punta Gorda) (08°17’00”S; 78°57’48”W). Although the...

Badania empiryczne na rzecz polityki kulturalnej. Retrospektywa

Tomasz Kukołowicz & Rafał Wiśniewski

Gazing Back and Looking Forward: Drug-Pricing Reform in 2019 and 2020

Jeremy Sharp & Ruth McDonald

La justice spatiale prend place.

Jacques Lévy, Ana Póvoas & Jean-Nicolas Fauchille
L’ouvrage Théorie de la justice spatiale (2018) est paru peu avant le déclenchement du mouvement des Gilets jaunes. L’importance des liens entre espace et justice présents dans le débat public qui s’est en suivi prouve que la dimension spatiale de la vie sociale est désormais perçue en France comme une composante non réductible aux autres, plus classiques, comme l’économique et la politique. Les concepts utiles pour penser cette dimension, proposés par le livre, répondent à...

Drug Price Moderation in Germany: Lessons for U.S. Reform Efforts

James C. Robinson, Patricia Ax & Dimitra Panteli
This issue brief details how Germany keeps medication costs low through centralized drug assessment, price negotiations, and price ceilings for noninnovative therapies – all with only modest government involvement. Insurers, providers, and patient advocacy groups all play key roles in the country’s drug pricing system.

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