7 Works

Modeling Hospital-Wide Extracorporeal Cardiopulmonary Resuscitation: Pros and Cons

Shiksha Joshi, Sandipan Shringi, Manpreet Sira & Maya Guglin
Background We aimed to analyze the potential benefits of implementing a hospital-wide extracorporeal cardiopulmonary resuscitation (ECPR) protocol. Methods We analyzed in-hospital cardiac arrests in a large, academic hospital for two consecutive years. For this model, we assumed that ECPR would be started in all adults, with no upper age limit, who have a full code status. We excluded codes lasting <15 minutes, arrests with asystole as an initial rhythm, and patients with hemorrhagic shock or...

Documentário clássico e a voz que não vemos: revisitando as noções de “voz de Deus” e “voz over”

Renan Chaves
The article revisits the notions of “voice of God” and “voice over” in the context of classic documentary film. From filmic and textual primary sources, the article seeks to demonstrate that such expressions do not support the stylistic variety and ethical perspectives in classic documentary film. So they should be problematized and acknowledge the existence of a diverse and complex field concerning the presence of the voice.

Unusual Case of Pump Thrombosis in LVAD Patient with COVID-19 — Diagnostic Challenges

William H. Frick, Ryan D. Mallory, Maya Guglin, Eve Anderson, Erin N. Lushin, Rey P. Vivo, Kashif Saleem & Roopa A. Rao
We present the first reported case of left ventricular assist device (LVAD) pump thrombosis in the setting of the coronavirus pandemic. We describe the clinical features of the case which helped to differentiate coronavirus disease 19 (COVID-19) from LVAD pump thrombosis. The patient is 56-year-old female supported by destination LVAD therapy. She was originally implanted with a HeartMate II device in 2015 and underwent two pump exchanges in 2017 and 2019 for pump thrombosis, despite...

Cangrelor: Safe and Effective for Left Ventricular Assist Device Thrombosis

Roopa Rao, Eve Anderson, Mark Jones, Muhamed Safiia & Maya Guglin
Pump thrombosis is a devastating complication of left ventricular assist device implantation as it increases the risk of mortality and morbidity. Early and effective treatment is important to prevent the progression of the clot and to avoid the surgical need for pump exchange or heart transplant. The current strategies of intensifying anticoagulation therapy are not consistently effective and carry significant bleeding risks. Cangrelor is a new pharmacological agent that has been utilized as an antiplatelet...

A Case of HeartMate 3 Outflow Graft Twisting with Extraluminal Thrombosis: Is Computed Tomography Angiography Helpful?

Karim Saleb, Marianna Zagurovskaya, Michael Sekela & Maya Guglin
Twists in the outflow graft of the HeartMateTM 3 device (Abbott) have recently been described as a sporadic, late complication. We present a case with a unique combination of external compression of the HeartMate 3 outflow graft by a surgical scar compounded by thrombus formation in the space between the band relief and the outflow graft with associated twist of the outflow graft and severe flow limitation. Computed tomography angiogram (CTA) of the chest was...

What Did We Learn about VADs in 2019?

Maya Guglin
This is our 6th annual literature review on mechanical circulatory support (MCS) devices. Our previous reports for 2014, 2015, 2016, 2017, 2018 were published as open access articles and were well received by the readers (1-5). In this paper, we summarize the most interesting and important, from our standpoint, publications from 2019. As we have done for the past two years, a section on extracorporeal membrane oxygenation (ECMO) is included and primarily addresses new developments...

A “Blinking” Left Ventricular Assist Device

Maya Guglin & Roopa Rao
Guglin M, Rao R. A ”Blinking” LVAD. The VAD Journal. 2020; 6(2):e2020627. https://doi.org/10.11589/vad/e2020627

Registration Year

  • 2021
  • 2019

Resource Types

  • Data Paper


  • Indiana University
  • University of Kentucky
  • Community Health Network
  • Saint Vincent Hospital
  • Cleveland Clinic